Emphysema presence, severity, and distribution has little impact on the clinical presentation of a cohort of patients with mild to moderate COPD.

abstract：BACKGROUND:The diagnostic yields with transbronchial needle aspiration (TBNA) for mediastinal nodes are highly variable. Nodal positions, as assessed on a breath-hold conventional CT scan, do not account for nodal motion. We studied nodal motion on four-dimensional (4D) CT scans. METHODS:A total of 47 mediastinal node...

journal_title：Chest

authors： Piet AH,Lagerwaard FJ,Kunst PW,van Sörnsen de Koste JR,Slotman BJ,Senan S

更新日期：2007-06-01 00:00:00

abstract：STUDY OBJECTIVES:To determine whether, in patients with bilateral pleural effusions, the main cellular and biochemical features of the pleural fluid on the right side differ from or correlate with those on the left side. We examined lactate dehydrogenase (LDH), glucose, and total protein (TP) levels, RBC count, nucleat...

journal_title：Chest

authors： Kalomenidis I,Rodriguez M,Barnette R,Gupta R,Hawthorne M,Parkes KB,Light RW

更新日期：2003-07-01 00:00:00

abstract：:In airway diseases such as asthma and COPD, specific structural changes may be observed, very likely secondary to an underlying inflammatory process. Although it is still controversial, airway remodeling may contribute to the development of these diseases and to their clinical expression and outcome. Airway remodeling...

journal_title：Chest

authors： Bergeron C,Boulet LP

更新日期：2006-04-01 00:00:00

abstract：:Atherosclerosis occurred in a coronary artery saphenous vein bypass graft. Serial angiograms are presented documenting subtotal occlusion of this graft which occurred over a nine-month period. Pathologic examination of graft material obtained at surgery demonstrated ulcerating atherosclerotic plaque. The occurrence of...

journal_title：Chest

authors： Hanlon JT,Massie B,Riches W,Wilson J,Ellis RJ,Gertz EW

更新日期：1981-01-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the usefulness of routinely inserting a hollow airway exchange catheter (jet stylet) prior to tracheal extubation of adult patients with risk factors for difficult tracheal intubation. DESIGN:Prospective, 1-year study of 40 consecutive patients undergoing mechanical ventilation who had one...

journal_title：Chest

authors： Loudermilk EP,Hartmannsgruber M,Stoltzfus DP,Langevin PB

更新日期：1997-06-01 00:00:00

abstract：STUDY OBJECTIVES:To validate capnometric recirculating gas tonometry (CRGT) for continuously monitoring gut intramucosal PCO2 (PiCO2) in a septic shock model, and to compare gastric vs esophageal PCO2 vs intramucosal-arterial PCO2 gradients. INTERVENTIONS:CRTG catheters were placed in the stomach and esophagus of six ...

journal_title：Chest

authors： Guzman JA,Lacoma FJ,Kruse JA

更新日期：1998-04-01 00:00:00

abstract：:It was previously thought that diagnostic or therapeutic ionizing radiation did not have an adverse effect on the function of cardiac pacemakers. Recently, however, some authors have reported damaging effect of the therapeutic radiation on cardiac pulse generators. An analysis of a recently-extracted pacemaker documen...

journal_title：Chest

authors： Pourhamidi AH

更新日期：1983-10-01 00:00:00

abstract：:This report describes a 25-year follow-up of angiographically proven bilateral functioning Vineberg grafts. This represents the longest angiographic follow-up found in the literature. The relevance of these grafts in present-day revascularization procedures is discussed. ...

journal_title：Chest

authors： Hughes MM

更新日期：1997-03-01 00:00:00

abstract：:A 51-year-old man developed fever, cough, and dyspnea 5 days after completing murine monoclonal anti-CD3 antibody (OKT3) treatment for acute cardiac allograft rejection. Samples of BAL fluid grew influenza A virus. Progressive pulmonary infiltrates, respiratory compromise, and hypoxia developed, and the patient ultima...

journal_title：Chest

authors： Embrey RP,Geist LJ

更新日期：1995-11-01 00:00:00

abstract：:Thoracic splenosis (post-traumatic autotransplantation of splenic tissue) is rare and generally asymptomatic. We report a patient with thoracic splenosis presenting with repeated hemoptysis. The blood supply of the hypervascular splenic transplants originated from a bronchial and an intercostal artery. Hemoptysis impr...

journal_title：Chest

authors： Cordier JF,Gamondes JP,Marx P,Heinen I,Loire R

更新日期：1992-08-01 00:00:00

abstract：:Continuous measurement of mixed venous oxygen saturation (SvO2) has been suggested as an adjunct in monitoring critically ill patients. We evaluated SvO2 monitoring in 24 patients suffering from complicated myocardial infarctions. Cardiac output and arterial lactate levels were measured when there were persistent 5 pe...

journal_title：Chest

authors： Kyff JV,Vaughn S,Yang SC,Raheja R,Puri VK

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the accuracy of a flow-proportional delivery system and the pattern of inspiratory nitric oxide (NO) concentration during different flow conditions. DESIGN:Laboratory study in a lung model. SETTING:University experimental laboratory. SUBJECT:With a new delivery system, NO was administered propo...

journal_title：Chest

authors： Sydow M,Bristow F,Zinserling J,Allen SJ

更新日期：1997-08-01 00:00:00

abstract：:KL-6, a mucinous high-molecular weight glycoprotein, expressed on type II pneumonocytes, is elevated in the serum of patients with active interstitial pneumonia. Forty-seven patients with histologically confirmed sarcoidosis were analyzed by chest radiography, CT, 67Ga scintigraphy, BAL fluid (BALF), and serum KL-6. S...

journal_title：Chest

authors： Kobayashi J,Kitamura S

更新日期：1996-05-01 00:00:00

abstract：:Bronchial thermoplasty (BT) involves the application of radiofrequency energy to visible proximal airways to selectively ablate airway smooth muscle. BT is the first nonpharmacologic interventional therapy approved by the US Food and Drug Administration (FDA) for severe asthma. This approval was based on the results o...

journal_title：Chest

authors： Iyer VN,Lim KG

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Human telomere disease consists of a wide spectrum of disorders, including pulmonary, hepatic, and bone marrow abnormalities. The extent of bone marrow and liver abnormalities in patients with interstitial lung disease (ILD) and short telomeres is unknown. METHODS:The lung transplant clinic established a pr...

journal_title：Chest

authors： George G,Rosas IO,Cui Y,McKane C,Hunninghake GM,Camp PC,Raby BA,Goldberg HJ,El-Chemaly S

更新日期：2015-06-01 00:00:00

abstract：:A 69-year-old man developed a rupture of the papillary muscle on the fifth day of acute posterior myocardial infarction. The two-dimensional echocardiographic features of ruptured papillary muscle included (1) mobile mass of echos attached to normal chordae tendineae in the left ventricle, (2) absent tip of papillary ...

journal_title：Chest

authors： Erbel R,Schweizer P,Bardos P,Meyer J

更新日期：1981-05-01 00:00:00

abstract：:One hundred forty patients with pleuropulmonary amebiasis were classified radiographically in order to rationalize therapy based on the use of metronidazole. Amebic testing with gel diffusion, serial chest x-ray films, and observation of the patient's response to treatment have dominated management of the patients, 13...

journal_title：Chest

authors： Cameron EW

更新日期：1978-05-01 00:00:00

abstract：:We studied eight patients with miliary tuberculosis (TB). In all instances, tuberculomatous lesions were demonstrated in the aspirated bone marrow. We conclude that the bone marrow aspiration has great value in diagnosing miliary TB because it provides sufficient material to permit examination of serial sections as ne...

journal_title：Chest

authors： Kinoshita M,Ichikawa Y,Koga H,Sumita S,Oizumi K

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:Symptomatic malignant pleural effusions are common sequelae in patients with certain malignancies. Pleurodesis via bedside thoracostomy is the current treatment option most commonly used. To our knowledge, this is the first prospective randomized trial to examine which agent, bleomycin or talc slurry, is supe...

journal_title：Chest

authors： Zimmer PW,Hill M,Casey K,Harvey E,Low DE

更新日期：1997-08-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate renal and vasodilator effects of synthetic atrial natriuretic factor (ANF) in patients undergoing cardiopulmonary bypass (CPB) with special reference to the applicability of ANF as a diuretic and natriuretic. DESIGN:The study consisted of two parts. The first 15 consecutive patients in a un...

journal_title：Chest

authors： Hynynen M,Palojoki R,Heinonen J,Tikkanen I,Harjula AL,Fyhrquist F

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:This study investigated sites of nitric oxide (NO) gas exchange and response to inhaled corticosteroids (ICS) in patients with COPD and varying extents of emphysema. METHODS:This was a prospective, randomized, single-blind, crossover study in treated, stable, ex-smoking patients with COPD who were ICS and l...

journal_title：Chest

authors： Gelb AF,Flynn Taylor C,Krishnan A,Fraser C,Shinar CM,Schein MJ,Osann K

更新日期：2010-03-01 00:00:00

abstract：:Platypnea-orthodeoxia is an uncommon syndrome that may occur due to the postpneumonectomy state, cirrhosis of the liver, recurrent pulmonary embolism, and intracardiac shunting. We describe a patient who was found to have a positional change in desaturation after being admitted for dehydration. Workup revealed an atri...

journal_title：Chest

authors： Acharya SS,Kartan R

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Pulmonary artery remodeling triggered by alveolar hypoxia is considered the main mechanism of pulmonary hypertension (PH) in COPD patients. We hypothesized that the risk for PH in COPD is increased by an elevation in the proinflammatory cytokines interleukin (IL)-6, monocyte chemoattractant protein-1 (MCP-1)...

journal_title：Chest

authors： Chaouat A,Savale L,Chouaid C,Tu L,Sztrymf B,Canuet M,Maitre B,Housset B,Brandt C,Le Corvoisier P,Weitzenblum E,Eddahibi S,Adnot S

更新日期：2009-09-01 00:00:00

abstract：:A 35-year-old male homosexual, a former intravenous drug abuser, was found to be human immunodeficiency virus (HIV) positive in 1984. He developed AIDS in 1987 and began treatment with zidovudine in 1989. One year later he developed left apical pleural blebs, a pneumothorax and an exudative pleural effusion. A maligna...

journal_title：Chest

authors： Behling CA,Wolf PL,Haghighi P

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the costs, consequences, effectiveness, and safety of ciprofloxacin vs standard antibiotic care in patients with an initial acute exacerbation of chronic bronchitis (AECB) as well as recurrent AECBs over a 1-year period. DESIGN:Randomized, multicenter, parallel-group, open-label study. SETTING:O...

journal_title：Chest

authors： Grossman R,Mukherjee J,Vaughan D,Eastwood C,Cook R,LaForge J,Lampron N

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular comorbidities have a negative impact on the health status and prognosis of patients with COPD. We determined whether nocturnal noninvasive (positive) mechanical ventilation (NIMV) can improve heart rate variability (HRV), decrease circulating natriuretic peptide levels, and improve functional ...

journal_title：Chest

authors： Sin DD,Wong E,Mayers I,Lien DC,Feeny D,Cheung H,Gan WQ,Man SF

更新日期：2007-01-01 00:00:00

abstract：:To determine work-of breathing with continuous positive airway pressure (CPAP) delivery systems, we used a lung model to simulate spontaneous breathing. "Additional work" during tidal breathing was derived by comparing change in airway pressure with change in tidal volume. Seven demand-flow CPAP delivery systems were ...

journal_title：Chest

authors： Katz JA,Kraemer RW,Gjerde GE

更新日期：1985-10-01 00:00:00

abstract：:Mechanical ventilation was able to induce a decrease in cardiac output and regional blood flow, especially hepatic flow. Thus, hepatic elimination of drugs with a high hepatic-extraction ratio, which was linked to alteration in hepatic blood flow, could be reduced during mechanical ventilation. The aim of this work wa...

journal_title：Chest

authors： Richard C,Berdeaux A,Delion F,Riou B,Rimailho A,Giudicelli JF,Auzépy P

更新日期：1986-12-01 00:00:00

abstract：:We treated five patients with a past history of tuberculous pleural infection that led to chronic, quiescent, loculated empyema. Reactivation of TB was associated with formation of BPF and recovery of drug-susceptible Mycobacterium tuberculosis from sputum. All patients had recurrence of positive sputum cultures that ...

journal_title：Chest

authors： Iseman MD,Madsen LA

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Septic pulmonary embolism (SPE) is an uncommon disorder with an insidious onset and is difficult to diagnose. STUDY OBJECTIVES:To characterize the presenting features and clinical course of patients with SPE. DESIGN:Retrospective study. SETTING:Tertiary care, referral medical center. PATIENTS:Fourteen su...

journal_title：Chest

authors： Cook RJ,Ashton RW,Aughenbaugh GL,Ryu JH

更新日期：2005-07-01 00:00:00