Role for interleukin-6 in COPD-related pulmonary hypertension.

abstract：STUDY OBJECTIVE:Factors influencing diastolic filling of the left ventricle may serve as critical determinants of both maximal cardiac output and oxygen uptake. This study was conducted to assess diastolic filling dynamics of the left ventricle during progressive upright cycle exercise in children. METHODS:Twelve boys...

journal_title：Chest

authors： Rowland T,Mannie E,Gawle L

更新日期：2001-07-01 00:00:00

abstract：:The presence of a null gene for alpha1-antitrypsin was detected in a family study by the inheritance of intermediate antitrypsin deficiency in association with a normal (PiM) phenotypic pattern. The proband, a 42-year-old man (M-phenotype), was a cigarette smoker and had physiologic evidence of pulmonary emphysema. Th...

journal_title：Chest

authors： Lieberman J,Gaidults L,Schleissner LA

更新日期：1976-10-01 00:00:00

abstract：OBJECTIVES:Tumor necrosis factor (TNF)-alpha is known to be a proinflammatory cytokine that has a pronounced negative inotropic effect and plays an important role in ischemic-reperfusion injury. METHODS:Twenty isolated rat hearts were randomly divided equally into two groups (heparin and non-heparin) and were perfused...

journal_title：Chest

authors： Pevni D,Frolkis I,Shapira I,Schwartz D,Yuhas Y,Schwartz IF,Chernichovski T,Uretzky G

更新日期：2005-09-01 00:00:00

abstract：:The accumulation of thrombin at sites of vascular injury provides one of the chief means for recruiting platelets into a growing hemostatic plug. Studies completed over the past 10 years show that platelet responses to thrombin are mediated by a subset of G protein-coupled receptors known as protease-activated recepto...

journal_title：Chest

authors： Brass LF

更新日期：2003-09-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the usefulness of routinely inserting a hollow airway exchange catheter (jet stylet) prior to tracheal extubation of adult patients with risk factors for difficult tracheal intubation. DESIGN:Prospective, 1-year study of 40 consecutive patients undergoing mechanical ventilation who had one...

journal_title：Chest

authors： Loudermilk EP,Hartmannsgruber M,Stoltzfus DP,Langevin PB

更新日期：1997-06-01 00:00:00

abstract：:A man with usual interstitial pneumonia (age of onset 58 years) was previously found to have an Ile73Thr (I73T) surfactant protein C (SFTPC) mutation. Genomic DNA from the individual and two daughters (aged 39 and 43 years) was sequenced for the I73T mutation and variations in ATP-binding cassette A3 (ABCA3). All thre...

journal_title：Chest

authors： Crossno PF,Polosukhin VV,Blackwell TS,Johnson JE,Markin C,Moore PE,Worrell JA,Stahlman MT,Phillips JA 3rd,Loyd JE,Cogan JD,Lawson WE

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:We investigated factors related to the diagnostic sensitivity of CT-guided transbronchial biopsy (TBB) using an ultrathin bronchoscope and virtual bronchoscopy (VB) navigation for small peripheral pulmonary lesions. METHOD:We have performed this procedure on 83 patients with 85 small peripheral pulmonary le...

journal_title：Chest

authors： Shinagawa N,Yamazaki K,Onodera Y,Asahina H,Kikuchi E,Asano F,Miyasaka K,Nishimura M

更新日期：2007-02-01 00:00:00

abstract：:We retrospectively evaluated the clinical effectiveness of a treatment schedule with intermittent positive pressure ventilation via nasal mask in 49 patients with acute exacerbations of COLD. According to the ability to successfully tolerate a preliminary trial with NIPPV, patients were submitted either to standard tr...

journal_title：Chest

authors： Foglio C,Vitacca M,Quadri A,Scalvini S,Marangoni S,Ambrosino N

更新日期：1992-06-01 00:00:00

abstract：STUDY OBJECTIVES:Sialomucin complex (SMC) is a heterodimeric glycoprotein, and is found on the surfaces of the mesothelia of the pleura, pericardium, and peritoneum. Sialomucins play a significant role in adhesion as well as in defense. In this study, we hypothesized that pleural mesothelial cells (PMCs) express SMC an...

journal_title：Chest

authors： Sharma RK,Mohammed KA,Nasreen N,Hardwick J,Van Horn RD,Ramirez-Icaza C,Antony VB

更新日期：2003-08-01 00:00:00

abstract：STUDY OBJECTIVE:To examine if the perception of dyspnea during normal pregnancy may be related to an inappropriate ventilatory response to the increased metabolic rate, due to a higher chemosensitivity. PATIENTS AND INTERVENTIONS:At weeks 12, 24, and 36 of gestation and 4 months after delivery, 11 healthy pregnant wom...

journal_title：Chest

authors： García-Rio F,Pino JM,Gómez L,Alvarez-Sala R,Villasante C,Villamor J

更新日期：1996-08-01 00:00:00

abstract：:We describe the case of a lung transplant patient with primary graft failure and an emphysematous native lung, who displayed different respiratory rates between the transplanted lung and the native lung. Inflation of the native lung delayed the next inspiratory effort relative to inflation of the denervated transplant...

journal_title：Chest

authors： Officer TM,Wheeler DR,Frost AE,Rodarte JR

更新日期：2001-08-01 00:00:00

abstract：:Forty-eight elderly patients with uncomplicated mild essential hypertension entered two drug regimens. In group 1, clonidine monotherapy (n = 15), clonidine was titrated to achieve goal blood pressure (less than 90 mm Hg diastolic) in dosages of 0.05 mg twice daily to 0.2 mg three times daily. Blood pressure decreased...

journal_title：Chest

authors： Thananopavarn C,Golub MS,Sambhi MP

更新日期：1983-02-01 00:00:00

abstract：:Patient-focused or patient-centered care is not a new concept, but its value has been overlooked in preference to the technology-based, disease-centered model that has prevailed in medicine for the last 50 years. Patient-focused care includes four broad areas of intervention: communication with patients, partnerships,...

journal_title：Chest

authors： Irwin RS,Richardson ND

更新日期：2006-07-01 00:00:00

abstract：:The neural mechanisms accompanying dynamic exercise of different intensities were analyzed in dogs and human subjects by means of autoregressive spectral analysis of heart period and arterial pressure variabilities. In the animal experiments, 8 conscious dogs were examined after implanting a solid state pressure gauge...

journal_title：Chest

authors： Rimoldi O,Furlan R,Pagani MR,Piazza S,Guazzi M,Pagani M,Malliani A

更新日期：1992-05-01 00:00:00

abstract：:Patients with regionally extensive non-small cell lung cancer (predominantly by virtue of metastases to mediastinal lymph nodes, less commonly by direct extension into the mediastinum) were treated predominantly with chest radiation therapy alone until the early 1980s. At that time, because of the high local recurrenc...

journal_title：Chest

authors： Eagan RT

更新日期：1994-12-01 00:00:00

abstract：:Between December 1985 and August 1988, there were 115 patients at 13 centers who were entered on a randomized comparison of tetracycline and bleomycin for treatment of malignant pleural effusions. Fifteen patients were not treated, primarily due to rapid progression of systemic cancer. Fifteen patients entered on a hi...

journal_title：Chest

authors： Ruckdeschel JC,Moores D,Lee JY,Einhorn LH,Mandelbaum I,Koeller J,Weiss GR,Losada M,Keller JH

更新日期：1991-12-01 00:00:00

abstract：:The purpose of our study was to determine the frequency of cardiac ectopy during the performance of flow-volume loops. The performance of an adequate flow-volume loop entails significant shifts in intrathoracic pressure and oxyhemoglobin saturation that could heighten myocardial arrhythmogenicity and lead to increased...

journal_title：Chest

authors： Fields CL,Byrd RP Jr,Ossorio MA,Roy TM,Michaels MJ,Vogel RL

更新日期：1993-04-01 00:00:00

abstract：:Proteomics is the study of the entire protein complement of the genome (the proteome) in a biological system. Proteomic studies require a multidisciplinary approach and have only been practical with the convergence of technical and methodologic improvements including the following: advances in mass spectrometry and ge...

journal_title：Chest

authors： Bowler RP,Ellison MC,Reisdorph N

更新日期：2006-08-01 00:00:00

abstract：STUDY OBJECTIVES:Black smokers have been reported to have higher serum cotinine levels than do white smokers, and have higher rates of most smoking-related diseases, despite smoking fewer cigarettes per day. Another striking racial difference is the preference for mentholated cigarettes among black smokers. The contrib...

journal_title：Chest

authors： Clark PI,Gautam S,Gerson LW

更新日期：1996-11-01 00:00:00

abstract：:Due to concerns about the efficacy and safety of using pulmonary artery catheterization to evaluate hemodynamic status, noninvasive diagnostic testing has gained increased importance. This article focuses on both the supportive evidence and the limitations of applying the vascular pedicle width (VPW), which is the med...

journal_title：Chest

authors： Ely EW,Haponik EF

更新日期：2002-03-01 00:00:00

abstract：:The resurgence of tuberculosis (TB) in the early 1990s, including multidrug-resistant strains, led health officials to recommend the use of involuntary detention for persistently nonadherent patients. Using a series of recently published articles on the subject, this paper offers some opinions on how detention program...

journal_title：Chest

authors： Lerner BH

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The measure of sputum eosinophil counts is a useful tool in the investigation of occupational asthma (OA), but processing sputum is time consuming. Measuring the fractional concentration of exhaled nitric oxide (FENO) may be an alternative in clinical practice. The aim of this study was to assess the respect...

journal_title：Chest

authors： Lemière C,D'Alpaos V,Chaboillez S,César M,Wattiez M,Chiry S,Vandenplas O

更新日期：2010-03-01 00:00:00

abstract：INTRODUCTION:CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2) have been shown to play an important role in transepithelial migration of neutrophil granulocytes during inflammation in various tissues. This study investigated the regulation of gene expression and surface expression of CXCR1 and CXCR2...

journal_title：Chest

authors： Farkas L,Hahn MC,Schmoczer M,Jentsch N,Krätzel K,Pfeifer M,Schulz C

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) and histamine type 2 receptor blockers (H2Bs) are used for stress ulcer prophylaxis. Although the PPIs have greater potency for acid suppression, their relative effectiveness for preventing clinically important GI bleeding (CIGIB) has not been established. The goal of this study...

journal_title：Chest

authors： Lilly CM,Aljawadi M,Badawi O,Onukwugha E,Tom SE,Magder LS,Harris I

更新日期：2018-09-01 00:00:00

abstract：:Pancreaticopleural fistula secondary to chronic pancreatitis is a rare cause of recurrent pleural effusion. The demonstration of the fistula with endoscopic retrograde pancreatography and CT is invasive or limited. We report in two patients the use of magnetic resonance pancreatography as a noninvasive alternative to ...

journal_title：Chest

authors： Materne R,Vranckx P,Pauls C,Coche EE,Deprez P,Van Beers BE

更新日期：2000-03-01 00:00:00

abstract：STUDY OBJECTIVES:COPD patients run a risk of developing nocturnal oxygen desaturation. When evaluating patients with nocturnal hypoxemia, an unfamiliar hospital environment and the monitoring equipment may cause sleep disturbances. It was hypothesized that increased sleep disruption will lead to fewer instances of desa...

journal_title：Chest

authors： Brijker F,van den Elshout FJ,Heijdra YF,Folgering HT

更新日期：2001-06-01 00:00:00

abstract：:A protocol was originally designed to study breathing control during and following cardiac arrest in humans, taking advantage of the period of pulseless ventricular fibrillation (PVF) produced while testing a newly implanted cardioverter-defibrillator device. A patient aged in his 60s with New York Heart Association c...

journal_title：Chest

authors： Bartsch S,Haouzi P

更新日期：2013-10-01 00:00:00

abstract：:As seen in this CME online activity (available at http://courses.elseviercme.com/694), idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive, fibrotic lung disease of unknown cause that is associated with substantial health-care utilization and high rates of mortality. The clinical symptoms of...

journal_title：Chest

authors： Martinez FJ,Lederer DJ

更新日期：2018-10-01 00:00:00

abstract：:We studied six patients with type A botulism to determine the degree of initial respiratory compromise and to quantitate the time course and extent of recovery of the ventilatory and upper airway muscles and exercise performance. The VM weakness was identified in all patients early after botulism. Upper airway muscle ...

journal_title：Chest

authors： Wilcox PG,Morrison NJ,Pardy RL

更新日期：1990-09-01 00:00:00

abstract：:Tracheal bronchus is a common anomaly that occurs in approximately 2% of people. Two children with multiple medical problems which led to endotracheal intubation are described. The hospital course for each child was complicated by persistent right upper lobe atelectasis. The presence of a tracheal bronchus was not rec...

journal_title：Chest

authors： O'Sullivan BP,Frassica JJ,Rayder SM

更新日期：1998-02-01 00:00:00