Acute lung disease in the immunocompromised host. Diagnostic accuracy of the chest radiograph.

Abstract:

PURPOSE:To assess the diagnostic accuracy of the chest radiograph in the evaluation of acute pulmonary complications in immunocompromised patients. METHODS:The study included the chest radiographs in 149 consecutive acute pulmonary complications seen in immunocompromised patients in whom a definitive diagnosis was made. Twenty-four complications were in patients with AIDS and 125 were in non-AIDS patients. The radiographs were separately reviewed in random order by two independent observers. The observers assessed pattern and distribution of radiographic findings and recorded their first-choice diagnosis. RESULTS:The most common complication in patients with AIDS was Pneumocystis carinii pneumonia (n = 21). In the non-AIDS patients, the most common complications included invasive aspergillosis (n = 25), drug reaction (n = 21), and Pneumocystis pneumonia (n = 20). A correct first-choice diagnosis was made in 90% of patients with AIDS and 34% of non-AIDS patients. IN AIDS patients with Pneumocystis pneumonia, the correct first-choice diagnosis was made in 41 of 42 (98%) readings by the two observers. In non-AIDS patients with invasive pulmonary aspergillosis, drug reaction, and Pneumocystis pneumonia, the correct first-choice diagnosis was made in 38%, 26%, and 43% of readings, respectively. CONCLUSION:The chest radiograph is helpful in the differential diagnosis of acute lung disease in the immunocompromised host, particularly in patients with AIDS.

journal_name

Chest

journal_title

Chest

authors

Logan PM,Primack SL,Staples C,Miller RR,Müller NL

doi

10.1378/chest.108.5.1283

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

1283-7

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)35704-X

journal_volume

108

pub_type

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