Intermediate alpha1-antitrypsin deficiency resulting from a null gene (M-phenotype).

abstract：:A patient with Ewing's sarcoma of the left scapula received prophylactic radiotherapy to the left lung following wide excision of the tumor. While the left lung remained free of tumor, there was metastatic invasion of the right lung within ten months of the initial diagnosis of the disease. Since Ewing's sarcoma frequ...

journal_title：Chest

authors： Mintz U,Keinan Z,Wainrach B

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Disease progression in COPD is associated with a decline in exercise performance over time. We assessed whether tiotropium might mitigate this by determining its effect on treadmill endurance time (ET) over 2 years. METHODS:This was a randomized, double-blind, placebo-controlled trial of tiotropium, 18 μg d...

journal_title：Chest

authors： Cooper CB,Celli BR,Jardim JR,Wise RA,Legg D,Guo J,Kesten S

更新日期：2013-08-01 00:00:00

abstract：STUDY OBJECTIVES:Despite the success of specialist cough clinics, there is increasing recognition of a subgroup of chronic coughers in whom a diagnosis cannot be made even after thorough, systematic investigation. We call this condition chronic idiopathic cough (CIC). The aim of this study is to compare the clinical ch...

journal_title：Chest

authors： Haque RA,Usmani OS,Barnes PJ

更新日期：2005-05-01 00:00:00

abstract：STUDY OBJECTIVE:Increasing evidence indicates that routine preoperative diagnostic spirometry (pulmonary function tests [PFTs]) before elective abdominal surgery does not predict individual risk of postoperative pulmonary complications and is overutilized. This economic evaluation estimates potential savings from reduc...

journal_title：Chest

authors： De Nino LA,Lawrence VA,Averyt EC,Hilsenbeck SG,Dhanda R,Page CP

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Characterizing acute exacerbations of COPD (AECOPD) and individualizing therapy is challenging. Key exacerbation therapies include antibiotics and systemic corticosteroids. Blood eosinophils, when either low or high, may offer a simple, inexpensive distinction to predict beneficial responses to these therapi...

journal_title：Chest

authors： MacDonald MI,Osadnik CR,Bulfin L,Hamza K,Leong P,Wong A,King PT,Bardin PG

更新日期：2019-07-01 00:00:00

abstract：STUDY OBJECTIVE:To elucidate the relationship of baseline glucose control and acute stimuli with hyperglycemia during medical critical illness. DESIGN:Prospective cohort study. SETTING:Medical ICU (MICU) of a university affiliated hospital. PATIENTS:Convenience sample of 100 medical patients meeting criteria for sev...

journal_title：Chest

authors： Cely CM,Arora P,Quartin AA,Kett DH,Schein RM

更新日期：2004-09-01 00:00:00

abstract：:The acute and chronic effects of fire fighting on pulmonary function were studied in 54 fire fighters from Connecticut, 32 smokers and 22 nonsmokers. Baseline studies of maximum expiratory flow-volume curves while breathing air and a mixture of 80 percent helium and 20 percent oxygen revealed obstruction of the small ...

journal_title：Chest

authors： Loke J,Farmer W,Matthay RA,Putman CE,Smith GJ

更新日期：1980-03-01 00:00:00

abstract：:Bronchoscopy specimens from 183 known/suspected acquired immunodeficiency syndrome patients were evaluated for pathogens. In each case, transbronchial biopsies were evaluated and bronchoalveolar lavage material was cultured for viruses, fungi and mycobacteria and examined cytologically. A specimen was considered posit...

journal_title：Chest

authors： Weldon-Linne CM,Rhone DP,Bourassa R

更新日期：1990-07-01 00:00:00

abstract：:A 3-month-old infant was brought to clinic for evaluation of recurrent apparent life-threatening events (ALTEs). Two ALTE episodes occurred while the infant was sleeping in a safety car seat. The first one occurred when he was 4 weeks old. His mother noticed that he was not breathing; he appeared limp with full body c...

journal_title：Chest

authors： DelRosso LM

更新日期：2015-04-01 00:00:00

abstract：STUDY OBJECTIVE:To describe the clinical characteristics and outcome of patients with severe melioidosis requiring intensive care. DESIGN:Retrospective chart review. SETTING:Two ICUs from a tertiary-care teaching hospital. PATIENTS:Twenty-seven adult ICU patients with microbiologically documented melioidosis. INTER...

journal_title：Chest

authors： Chan KP,Low JG,Raghuram J,Fook-Chong SM,Kurup A

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To study the incidence and severity of organ dysfunction associated with sepsis. DESIGN:Comprehensive review of prospectively collected data from intensive care patients hospitalized between 1997 and 2001. SETTING:Thirty-five ICUs in nonuniversity and university hospitals located in the Paris area. PATIENT...

journal_title：Chest

authors： Guidet B,Aegerter P,Gauzit R,Meshaka P,Dreyfuss D,CUB-Réa Study Group.

更新日期：2005-03-01 00:00:00

abstract：:Two patients had a vessel-like aortopulmonary "window" which could be ligated without the institution of cardiopulmonary bypass. While embryologically and functionally these communications are identical to the classic aortopulmonary "window," it is suggested that the term "aortopulmonary communication" is more appropr...

journal_title：Chest

authors： Belcourt CL,Aterman K,Gillis DA,Roy DL

更新日期：1979-03-01 00:00:00

abstract：:Three patients had hypertrophic obstructive cardiomyopathy and coronary artery spasm. The clinical diagnosis of hypertrophic obstructive cardiomyopathy, in all patients, was confirmed by echocardiography and angiography. Significant spasm of the right coronary artery was demonstrated in each patient by selective coron...

journal_title：Chest

authors： Mautner RK,Thomas I,Dhurandhar R,Phillips JH

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:The new GOLD (Global Initiative for Chronic Obstructive Lung Disease) strategy recommends use of the COPD Assessment Test (CAT) or modified Medical Research Council (mMRC) scale to assess symptoms in COPD against "risk" as assessed by spirometry or exacerbation frequency. We aimed to determine the concordanc...

journal_title：Chest

authors： Pillai AP,Turner AM,Stockley RA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Much controversy persists regarding the place of statin drugs in the treatment of patients with COPD. This systematic review and meta-analysis sought to determine the clinical efficacy of statin therapy in COPD. METHODS:We searched MEDLINE, EMBASE, the Cochrane Database, and PubMed for relevant clinical stu...

journal_title：Chest

authors： Zhang W,Zhang Y,Li CW,Jones P,Wang C,Fan Y

更新日期：2017-12-01 00:00:00

abstract：:Negative pressure pulmonary edema (NPPE) is an important cause of noncardiogenic pulmonary edema but is rarely reported in the setting of bronchospasm. A 43-year-old woman with severe reactive airway disease suffered an episode of severe bronchospasm after endotracheal extubation following an otherwise uneventful gene...

journal_title：Chest

authors： Krodel DJ,Bittner EA,Abdulnour RE,Brown RH,Eikermann M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Morbid obesity produces a variety of ECG alterations, including leftward shifts of the P-wave, QRS, and T-wave axes; disproportionately high frequencies of low QRS voltage; left ventricular hypertrophy and left atrial abnormality; and a high frequency of T-wave flattening in the inferior and lateral leads. T...

journal_title：Chest

authors： Alpert MA,Terry BE,Hamm CR,Fan TM,Cohen MV,Massey CV,Painter JA

更新日期：2001-02-01 00:00:00

abstract：:Systemically bioavailable leukotriene receptor antagonists (LTRAs) can reduce the essential components of allergic inflammation in allergic rhinitis (AR) and asthma by blocking cysteinyl leukotriene (CysLT) activity, resulting in a wide range of clinical effects. CysLTs, mediators, and modulators in the pathophysiolog...

journal_title：Chest

authors： Busse W,Kraft M

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Little information is available about the prevalence of deep vein thrombosis (DVT) after discharge from cardiac surgery units and its impact on rehabilitation programs. OBJECTIVES:To estimate the rate of DVT, in relation to different thromboprophylaxis strategies, in patients with a recent coronary artery b...

journal_title：Chest

authors： Ambrosetti M,Salerno M,Zambelli M,Mastropasqua F,Tramarin R,Pedretti RF

更新日期：2004-01-01 00:00:00

abstract：:Coronary arteriovenous fistula is an uncommon, although not rare, congenital cardiac malformation, especially in the adult. Most such reported such cases have involved but a single coronary vessel. This report documents the second case of coronary arteriovenous fistulae involving the right and circumflex coronary vess...

journal_title：Chest

authors： Babb JD,Field JM

更新日期：1977-11-01 00:00:00

abstract：:To assess the value of bronchoalveolar lavage (BAL) for diagnosis, understanding, and treatment of amiodarone-associated pneumonitis, we examined the results of BAL total and differential cell counts and phenotyping of lymphocytes in 22 patients with this lung disorder and in 33 normal subjects. Overall, the total cel...

journal_title：Chest

authors： Akoun GM,Cadranel JL,Blanchette G,Milleron BJ,Mayaud CM

更新日期：1991-05-01 00:00:00

abstract：:A 62-year-old man with a long history of lung disease developed atelectasis of the right middle lung lobe, caused by a protrusion in the wall of the middle lobe bronchus. A biopsy was performed in the suspicious region. This was immediately followed by massive arterial bleeding into the airways and complicated by card...

journal_title：Chest

authors： Maxeiner H

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:We recently showed that administration of the combination of the noradrenergic drug atomoxetine plus the antimuscarinic oxybutynin (ato-oxy) prior to sleep greatly reduced OSA severity, likely by increasing upper airway dilator muscle activity during sleep. In patients with OSA who performed the ato-oxy tria...

journal_title：Chest

authors： Taranto-Montemurro L,Messineo L,Azarbarzin A,Vena D,Hess LB,Calianese NA,White DP,Wellman A,Sands SA

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVES:This multicenter, double-blind, placebo-controlled study evaluated the dose response to 6 weeks of triamcinolone acetonide inhalation aerosol (TAA, 100 microg per puff) in patients with moderately severe asthma. STUDY DESIGN:A total of 285 patients were randomly assigned to treatment with 1, 2, 4, or 8 puff...

journal_title：Chest

authors： Welch MJ,Levy S,Smith JA,Feiss G,Farrar JR

更新日期：1997-09-01 00:00:00

abstract：INTRODUCTION:Osteoporosis is a common condition in patients with end-stage lung disease, but little attention has been given to bone disease in patients with primary pulmonary hypertension (PPH). The purposes of this study were as follows: (1) to determine the prevalence of osteoporosis in patients with severe PPH befo...

journal_title：Chest

authors： Tschopp O,Schmid C,Speich R,Seifert B,Russi EW,Boehler A

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Asthma morbidity and mortality are higher in the United States for African-American (AA) children when compared to European-American (EA) children. STUDY OBJECTIVES:To explore racial differences in physiologic factors associated with pediatric asthma severity. DESIGN:Cross-sectional. METHODS:We analyzed d...

journal_title：Chest

authors： Joseph CL,Ownby DR,Peterson EL,Johnson CC

更新日期：2000-05-01 00:00:00

abstract：:The purpose of this study was to identify the strengths and limitations of using portable peak flowmeters to document suspected cases of occupational asthma that were reported to a statewide surveillance project. The New Jersey Department of Health conducts surveillance for occupational asthma as part of the federally...

journal_title：Chest

authors： Henneberger PK,Stanbury MJ,Trimbath LS,Kipen HM

更新日期：1991-12-01 00:00:00

abstract：:A patient had left ventricular pseudoaneurysm after mitral valve replacement surgery. The diagnosis was made by color flow Doppler demonstration of systolic flow between the left ventricular chamber and an echo-free space posterior to the heart which was initially interpreted as localized pleural effusion. Color Doppl...

journal_title：Chest

authors： Alam M,Rosman HS,Lewis JW,Brymer JF

更新日期：1989-01-01 00:00:00

abstract：:Lymphoid interstitial pneumonia (LIP) is regarded as both a disease and a nonneoplastic, inflammatory pulmonary reaction to various external stimuli or systemic diseases. It is an uncommon condition with incidence and prevalence rates that are largely unknown. Liebow and Carrington originally classified LIP as an idio...

journal_title：Chest

authors： Swigris JJ,Berry GJ,Raffin TA,Kuschner WG

更新日期：2002-12-01 00:00:00

abstract：:Because T-piece breathing may impair oxygenation, the best airway pressure from which to extubate ventilated patients is controversial. We compared the effects of extubation after 1 h of either CPAP 5 and T-piece/ZEEP. Once weaned from mechanical ventilation and breathing spontaneously, 106 patients were randomized to...

journal_title：Chest

authors： Jones DP,Byrne P,Morgan C,Fraser I,Hyland R

更新日期：1991-12-01 00:00:00