Effect of weight loss on the ECG of normotensive morbidly obese patients.

Abstract:

BACKGROUND:Morbid obesity produces a variety of ECG alterations, including leftward shifts of the P-wave, QRS, and T-wave axes; disproportionately high frequencies of low QRS voltage; left ventricular hypertrophy and left atrial abnormality; and a high frequency of T-wave flattening in the inferior and lateral leads. This study was designed to assess the effects of substantial weight loss on the ECG in morbid obesity. METHODS:We performed a resting 12-lead ECG on 60 normotensive patients (48 women and 12 men; mean +/- SD age, 37 +/- 7 years), whose body weight was twice their ideal body weight prior to and at the time of maximum weight loss after bariatric surgery. RESULTS:Mean weight decreased from 136 +/- 7 to 85 +/- 3 kg. Weight loss produced significant decreases in the frequencies of low QRS voltage; Romhilt-Estes point score > or = 5 points; SV(1) + RV(5) or V(6) > 35 mm; RV(5) or V(6) > 26 mm; RaVL > 11 mm; RaVL > or = 7.5 mm; SaVR > 14 mm; P-terminal force more negative than - 0.04 mm.s in lead V(1); and T-wave flattening in the inferior, lateral, and inferolateral leads. Weight loss significantly shifted the mean P-wave, QRS, T-wave axes rightward, and significantly reduced mean RaVL and mean SaVR voltage. CONCLUSION:Substantial weight loss is capable of reversing many of the ECG alterations associated with morbid obesity.

journal_name

Chest

journal_title

Chest

authors

Alpert MA,Terry BE,Hamm CR,Fan TM,Cohen MV,Massey CV,Painter JA

doi

10.1378/chest.119.2.507

subject

Has Abstract

pub_date

2001-02-01 00:00:00

pages

507-10

issue

2

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)38229-5

journal_volume

119

pub_type

杂志文章

相关文献

CHEST文献大全
  • The lungs and causes of death in the nocturnal oxygen therapy trial.

    abstract::Autopsy findings and a morphometric study of the lungs were compared in 18 subjects receiving nocturnal oxygen and 15 receiving continuous oxygen in the National Heart, Lung, and Blood Institute Nocturnal Oxygen Therapy Trial (about half of those who died). The emphysema score, average interalveolar wall distance, cen...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.86.2.230

    authors: Jacques J,Cooney TP,Silvers GW,Petty TL,Wright JL,Thurlbeck WM

    更新日期:1984-08-01 00:00:00

  • Bed partners' assessment of nasal continuous positive airway pressure therapy in obstructive sleep apnea.

    abstract:STUDY OBJECTIVE:This study aimed to evaluate the effects of nasal continuous positive airway pressure (nCPAP) therapy on sleep and daytime symptoms of bed partners and patients with obstructive sleep apnea (OSA). DESIGN:A cross-sectional questionnaire survey. SETTING:The sleep laboratory of a university teaching hosp...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.111.5.1261

    authors: Kiely JL,McNicholas WT

    更新日期:1997-05-01 00:00:00

  • Noninvasive pressure support ventilation in patients with acute respiratory failure.

    abstract::To further delineate indications for noninvasive pressure support ventilation (NIPSV), we proposed this noninvasive technique as an alternative to endotracheal intubation in 17 consecutive patients with acute respiratory failure from various causes. Eight patients (47 percent) were successfully ventilated with NIPSV, ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.3.907

    authors: Wysocki M,Tric L,Wolff MA,Gertner J,Millet H,Herman B

    更新日期:1993-03-01 00:00:00

  • Asthma and Cushing's syndrome.

    abstract::A female patient was treated with high-dose inhaled fluticasone propionate for her asthma. Over 2 years, she developed features of Cushing's syndrome with proximal myopathy, osteopenia, hypertension, depressive psychosis, and cushingoid appearance. She had biochemical evidence of marked adrenal suppression with a 9:00...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.117.2.593

    authors: Wilson AM,Blumsohn A,Jung RT,Lipworth BJ

    更新日期:2000-02-01 00:00:00

  • Thoracotomy for postchemotherapy resection of pulmonary residual tumor mass in patients with nonseminomatous testicular germ cell tumors: aggressive surgical resection is justified.

    abstract::In patients with disseminated nonseminomatous testicular germ cell tumors (NSTGCT), a retroperitoneal residual tumor mass (RRTM) and/or a pulmonary residual tumor mass (PRTM) are often present after successful treatment with cisplatin-based polychemotherapy. Results and complications of postchemotherapy resection of P...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.112.4.967

    authors: Gels ME,Hoekstra HJ,Sleijfer DT,Nijboer AP,Molenaar WM,Ebels T,Schraffordt Koops H

    更新日期:1997-10-01 00:00:00

  • Disagreements in chest roentgen interpretation.

    abstract::Each of 100 chest radiographs selected randomly from a hospital population were read by five experienced radiologists. The films were rich in abnormal findings. Disagreement analysis was performed considering the entire content of the interpretation. The disagreements were graded by a panel as to type (false negative,...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.68.3.278

    authors: Herman PG,Gerson DE,Hessel SJ,Mayer BS,Watnick M,Blesser B,Ozonoff D

    更新日期:1975-09-01 00:00:00

  • Maximal exercise testing for the selection of heart transplantation candidates: limitation of peak oxygen consumption.

    abstract:BACKGROUND:Peak exercise oxygen consumption (peak VO2), which is considered an indicator of prognosis in advanced heart failure, is currently being used as a major criterion in many centers for the selection of candidates for heart transplantation. Available studies suggest that patients with peak VO2 < 14 mL/min/kg ha...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.2.410

    authors: Ramos-Barbón D,Fitchett D,Gibbons WJ,Latter DA,Levy RD

    更新日期:1999-02-01 00:00:00

  • Acute diverticulitis following cardiac surgery.

    abstract::Gastrointestinal complications requiring surgical correction following cardiopulmonary bypass most frequently involve the upper gastrointestinal tract. Surgical diseases of the colon are quite unusual in this setting. We recently performed cardiac surgery on three patients who developed acute diverticulitis requiring ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.89.5.756

    authors: Burton NA,Albus RA,Graeber GM,Lough FC

    更新日期:1986-05-01 00:00:00

  • Expression of alveolar macrophage adhesion molecules in pulmonary sarcoidosis.

    abstract::Beta-2-integrins belong to a family of leukocyte surface glycoproteins that are essential for immune functions of bronchoalveolar cells. The expression of three alpha chains designed as CD11a, CD11b, CD11c, a common beta chain CD18, and of a ligand for several integrins CD54 (ICAM-1) was studied on alveolar macrophage...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.3.882

    authors: Striz I,Wang YM,Kalaycioglu O,Costabel U

    更新日期:1992-09-01 00:00:00

  • Trends in mechanical ventilation among patients hospitalized with acute exacerbations of COPD in the United States, 2001 to 2011.

    abstract:BACKGROUND:The use of noninvasive ventilation (NIV) in acute exacerbation of COPD has increased over time. However, little is known about patient factors influencing its use in routine clinical practice. METHODS:This was a retrospective cohort study of 723,560 hospitalizations for exacerbation of COPD at 475 hospitals...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.14-1216

    authors: Stefan MS,Shieh MS,Pekow PS,Hill N,Rothberg MB,Lindenauer PK

    更新日期:2015-04-01 00:00:00

  • Daytime sleepiness in patients with congestive heart failure and Cheyne-Stokes respiration.

    abstract:STUDY OBJECTIVE:To determine whether patients with congestive heart failure who develop Cheyne-Stokes respiration (CSR) during sleep experience excessive daytime sleepiness. This was addressed by comparing sleep quality and daytime sleepiness in three groups: patients with CHF and CSR during sleep (CSR group), patients...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.4.952

    authors: Hanly P,Zuberi-Khokhar N

    更新日期:1995-04-01 00:00:00

  • Acute electrophysiologic effects of inhaled salbutamol in humans.

    abstract:STUDY OBJECTIVES:Although inhaled beta2-agonists are in widespread use, several reports question their potential arrhythmogenic effects. The purpose of this study was to evaluate the cardiac electrophysiologic effects of a single, regular dose of an inhaled beta2-agonist in humans. DESIGN:Prospective study. SETTING:T...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.127.6.2057

    authors: Kallergis EM,Manios EG,Kanoupakis EM,Schiza SE,Mavrakis HE,Klapsinos NK,Vardas PE

    更新日期:2005-06-01 00:00:00

  • Lung health in sawmill workers exposed to pine and spruce.

    abstract::Workers exposed to a variety of wood dusts have been shown to exhibit occupational asthma, lung function deficits, and elevated levels of respiratory symptoms. Despite the popularity of pine and spruce, the health effects of exposures to these woods have not been extensively investigated. A study was undertaken to inv...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.3.642

    authors: Hessel PA,Herbert FA,Melenka LS,Yoshida K,Michaelchuk D,Nakaza M

    更新日期:1995-09-01 00:00:00

  • Naloxone and naltrexone. Application in COPD.

    abstract::The narcotic antagonists naloxone and naltrexone were used as respiratory stimulants in two patients failing traditional medical therapy for COPD. Both patients demonstrated improvement while receiving the drugs, but developed respiratory failure when they were discontinued abruptly. In selected patients with COPD, na...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.1.217

    authors: Reents SB,Beck CA Jr

    更新日期:1988-01-01 00:00:00

  • Evaluation of right ventricular performance with a right ventricular ejection fraction thermodilution catheter and MRI in patients with pulmonary hypertension.

    abstract:STUDY OBJECTIVES:We sought to compare catheter studies using a right ventricular ejection fraction (REF) catheter together with echocardiography and MRI in patients with pulmonary hypertension. PATIENTS AND METHODS:We compared hemodynamic findings, echocardiography, and MRI studies in 16 patients with pulmonary hypert...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.120.2.502

    authors: Hoeper MM,Tongers J,Leppert A,Baus S,Maier R,Lotz J

    更新日期:2001-08-01 00:00:00

  • Diaphragm Weakness in the Critically Ill: Basic Mechanisms Reveal Therapeutic Opportunities.

    abstract::The diaphragm is the primary muscle of inspiration. Its capacity to respond to the load imposed by pulmonary disease is a major determining factor both in the onset of ventilatory failure and in the ability to successfully separate patients from ventilator support. It has recently been established that a very large pr...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2018.08.1028

    authors: Petrof BJ

    更新日期:2018-12-01 00:00:00

  • Development of a giant bulla after lung volume reduction surgery.

    abstract::Lung volume reduction surgery (LVRS) is being evaluated in the treatment of emphysema. The proposed mechanisms of improvement are increased elastic recoil of the lung and improved mechanical efficiency of the muscles of respiration. We report a unique patient with emphysema who developed a giant bulla 3 years subseque...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.116.6.1809

    authors: Iqbal M,Rossoff L,McKeon K,Graver M,Scharf SM

    更新日期:1999-12-01 00:00:00

  • The use of home spirometry in detecting acute lung rejection and infection following heart-lung transplantation.

    abstract::The value of home spirometry in detecting acute lung rejection and opportunistic infections was studied in 15 heart-lung transplant recipients over a six-month period. The patients measured their FEV1 and FVC twice daily at home using a portable turbine spirometer. The records were then reviewed in relation to the res...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.97.2.353

    authors: Otulana BA,Higenbottam T,Ferrari L,Scott J,Igboaka G,Wallwork J

    更新日期:1990-02-01 00:00:00

  • Toxic-oil syndrome. Gallium-67 scanning and bronchoalveolar lavage studies in patients with abnormal lung function.

    abstract::The toxic-oil syndrome (TOS) is a multisystem disorder whose etiology and pathogenesis are as yet unknown. Lung alterations persist in a significant number of TOS patients due to the underlying vascular lesion. Computer-assisted 67Ga scanning and bronchoalveolar lavage (BAL) studies were performed in 14 TOS patients w...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.88.3.398

    authors: De la Cruz JL,Oteo LA,López C,Curto LM,Burgaleta C,Campos A,Sueiro A

    更新日期:1985-09-01 00:00:00

  • Re-evaluation of bone marrow aspiration in the diagnosis of miliary tuberculosis.

    abstract::We studied eight patients with miliary tuberculosis (TB). In all instances, tuberculomatous lesions were demonstrated in the aspirated bone marrow. We conclude that the bone marrow aspiration has great value in diagnosing miliary TB because it provides sufficient material to permit examination of serial sections as ne...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.3.690

    authors: Kinoshita M,Ichikawa Y,Koga H,Sumita S,Oizumi K

    更新日期:1994-09-01 00:00:00

  • Tuberculosis in Korea. The relationship between prior therapy and drug resistance.

    abstract::A review of 121 culture-positive cases of pulmonary tuberculosis from 1979 to 1984, including both Korean and American patients, at the major US military hospital in Korea indicated that most antituberculosis drug resistance occurred in patients with a history of previous antituberculosis therapy. The 98 patients with...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.90.2.247

    authors: Etzkorn ET,Lillis PK,McAllister CK

    更新日期:1986-08-01 00:00:00

  • Effects of long-term aerosol pentamidine for Pneumocystis carinii prophylaxis on pulmonary function.

    abstract:OBJECTIVE:The purpose of the study was to evaluate the long-term effects of aerosolized pentamidine (AP) on the pulmonary function of HIV-positive individuals receiving AP for Pneumocystis carinii pneumonia (PCP) prophylaxis. DESIGN:A retrospective analysis of serial pulmonary function tests (PFTs) performed on a coho...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.114.3.742

    authors: Wei CC,Pack LL,Chan CK

    更新日期:1998-09-01 00:00:00

  • Immunosuppressive therapy in connective tissue diseases-associated pulmonary arterial hypertension.

    abstract:STUDY OBJECTIVE:Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. Immunosuppressive therapy should be better evaluated in this setting. STUDY DESIGN:Monocentric retrospective study. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.1.182

    authors: Sanchez O,Sitbon O,Jaïs X,Simonneau G,Humbert M

    更新日期:2006-07-01 00:00:00

  • Effects of nutritional status on exercise performance in advanced cystic fibrosis.

    abstract::Initial evaluation of 22 patients with cystic fibrosis (CF) on entry into a trial of home oxygen therapy was used to elucidate the possible effects of poor nutritional status on exercise performance in CF. The patients had advanced lung disease (mean FEV1, 36 percent predicted) and all had a stable resting PaO2 less t...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.90.3.375

    authors: Marcotte JE,Canny GJ,Grisdale R,Desmond K,Corey M,Zinman R,Levison H,Coates AL

    更新日期:1986-09-01 00:00:00

  • CPAP reduces inspiratory work more than dyspnea during hyperinflation with intrinsic PEEP.

    abstract::Hyperinflation with intrinsic positive end-expiratory pressure (PEEPi) loads the respiratory muscles and causes dyspnea in obstructive lung disease. Continuous positive airway pressure (CPAP) has shown some efficacy in reducing inspiratory work and dyspnea. However, in obstructive lung disease, inspiratory work and dy...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.108.2.432

    authors: Fessler HE,Brower RG,Permutt S

    更新日期:1995-08-01 00:00:00

  • Formoterol suspension aerosol. Comparison with formoterol solution aerosol for 12 weeks in asthmatic patients.

    abstract:UNLABELLED:Formoterol solution aerosol has proved to be a fast and long-acting beta 2-sympathicomimetic drug in many clinical trials. The physical stability, however, was such that storage needed to be at 4 degrees C to 8 degrees C before first use; afterwards, the aerosol could be used for another three months at room...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.102.5.1544

    authors: Maesen FP,Nakratzas G,Bantje TA,Prins J,Zweers PG

    更新日期:1992-11-01 00:00:00

  • Increasing doses of inhaled corticosteroids compared to adding long-acting inhaled beta2-agonists in achieving asthma control.

    abstract:BACKGROUND:Combination therapy with inhaled corticosteroids (ICSs) and long-acting beta(2)-agonists (LABAs), or treatment with high doses of ICSs alone improves asthma control when therapy with low-dose ICSs is not sufficient. However, it is not known which of these treatment options is more effective in sustaining ast...

    journal_title:Chest

    pub_type: 杂志文章,随机对照试验

    doi:10.1378/chest.08-1018

    authors: O'Byrne PM,Naya IP,Kallen A,Postma DS,Barnes PJ

    更新日期:2008-12-01 00:00:00

  • Bronchogenic cancer in patients under 40 years old. The experience of a Latin American country.

    abstract::Lung cancer in young patients is increasing in frequency, as documented by data from the United States, Canada, Japan, and European countries. However, to date and to our knowledge, there have not been any reports from Latin America on this topic. The published reports show that lung cancer in young patients is associ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.5.1477

    authors: Green LS,Fortoul TI,Ponciano G,Robles C,Rivero O

    更新日期:1993-11-01 00:00:00

  • When is a biopsy-proven diagnosis necessary before stereotactic ablative radiotherapy for lung cancer?: A decision analysis.

    abstract:BACKGROUND:The practice of treating a solitary pulmonary nodule (SPN) suspicious for stage I non-small cell lung cancer (NSCLC) with stereotactic ablative radiotherapy (SABR) in the absence of pathology is growing. In the absence of randomized evidence, the appropriate prior probability threshold of lung cancer of when...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.13-2924

    authors: Louie AV,Senan S,Patel P,Ferket BS,Lagerwaard FJ,Rodrigues GB,Salama JK,Kelsey C,Palma DA,Hunink MG

    更新日期:2014-10-01 00:00:00

  • Thoracoscopic lobectomy for lung cancer with a largely fused fissure.

    abstract:BACKGROUND:While isolating the pulmonary arterial branches within the fissure is a crucial step in lobectomy, a largely fused fissure usually hinders its achievement, making lobectomy with video-assisted thoracoscopic surgery (VATS) difficult to achieve. For VATS lobectomy in lung cancer patients with a largely fused f...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.123.2.619

    authors: Nomori H,Ohtsuka T,Horio H,Naruke T,Suemasu K

    更新日期:2003-02-01 00:00:00