From subclinical alveolitis to granulomatosis. Sequential evaluation of pulmonary involvement in extrathoracic sarcoidosis.

Abstract:

:Follow-up of patients with subclinical inflammatory alveolitis associated with systemic diseases may represent the best opportunity to study the mechanisms responsible for the development of interstitial lung disease. We report a seven-year sequential pulmonary evaluation of one patient with clinically isolated gastric sarcoidosis, treated by gastrectomy, without evidence of clinical, radiologic or functional lung impairment and with chronic subclinical lymphocyte alveolitis. Five years later, she developed an overt interstitial lung disease characterized by fine crackles, diffuse parenchymal opacities and impaired diffusing capacity, preceded by an expansion of polymorphonuclear neutrophils in the lower respiratory tract, raising the hypothesis that these cells may be implicated in the pathogenesis of pulmonary derangement in sarcoidosis. This observation illustrates the importance of pulmonary follow-up of unaffected patients with systemic diseases and with subclinical inflammatory alveolitis, and the potential predictive value of neutrophil alveolitis in the pulmonary outcome of these patients.

journal_name

Chest

journal_title

Chest

authors

Dugas M,Wallaert B,Tonnel AB,Voisin C

doi

10.1378/chest.96.4.931

subject

Has Abstract

pub_date

1989-10-01 00:00:00

pages

931-3

issue

4

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)40481-7

journal_volume

96

pub_type

杂志文章

相关文献

CHEST文献大全
  • A 61-Year-Old Caribbean Man With Thrush and Acute Respiratory Failure.

    abstract:CASE PRESENTATION:A 61-year-old Caribbean man presented to the ED with dyspnea that had progressed over the previous week with associated cough and high fevers. Four days prior to admission, his primary care physician noted oral thrush and obtained a chest radiograph that revealed a right middle lobe infiltrate. He was...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2017.11.001

    authors: Gong J,Melamud A,Koenig S

    更新日期:2018-07-01 00:00:00

  • Automatic objective diagnosis of lymph nodal disease by B-mode images from convex-type echobronchoscopy.

    abstract:BACKGROUND:We investigated whether artificial neural networks (ANNs) could diagnose pathology of lymph nodes by feeding B-mode images from convex-type echobronchoscopy to ANNs. METHODS:Subjects comprised 91 patients who had undergone endobronchial ultrasonography transbronchial needle aspiration at our hospital betwee...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.07-1497

    authors: Tagaya R,Kurimoto N,Osada H,Kobayashi A

    更新日期:2008-01-01 00:00:00

  • Patient-Level Trajectories and Outcomes After Low-Dose CT Screening in the National Lung Screening Trial.

    abstract:BACKGROUND:Shared decision-making is an essential element of low-dose CT (LDCT) screening for lung cancer. Understanding patient-level outcomes from the National Lung Screening Trial (NLST) is critical to effectively communicate risks and benefits of screening to patients. METHODS:We performed a secondary analysis of ...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.chest.2019.06.016

    authors: Iaccarino JM,Silvestri GA,Wiener RS

    更新日期:2019-11-01 00:00:00

  • Cost analyses of community-acquired pneumonia from the hospital perspective.

    abstract:STUDY OBJECTIVES:Community-acquired pneumonia (CAP) is a widespread disease with important implications for health-care systems worldwide. This study investigated direct costs, treatment patterns, and outcomes associated with two patient cohorts hospitalized with CAP. DESIGN:The study design was naturalistic, prospect...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.128.4.2238

    authors: Bauer TT,Welte T,Ernen C,Schlosser BM,Thate-Waschke I,de Zeeuw J,Schultze-Werninghaus G

    更新日期:2005-10-01 00:00:00

  • Value of in situ elemental microanalysis in the histologic diagnosis of silicosis.

    abstract::Pulmonary specimens obtained from ten normal subjects and 53 patients with various pulmonary diseases were studied with energy-dispersive x-ray analysis. The amount of silicon in the pulmonary tissue was determined and expressed as a silicon/sulfur (Si/S) ratio. This Si/S ratio was below 0.2 in the ten normal subjects...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.85.4.506

    authors: Funahashi A,Schlueter DP,Pintar K,Siegesmund KA

    更新日期:1984-04-01 00:00:00

  • Detection and evaluation of asymptomatic myocarditis in schoolchildren: report of four cases.

    abstract:STUDY OBJECTIVE:Data on the prevalence of myocarditis in children are limited. Autopsy studies have shown that myocarditis is often undiagnosed. We attempted to investigate the clinical features of asymptomatic myocarditis in four schoolchildren detected during a mass ECG screening in schoolchildren. DESIGN AND SETTIN...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.116.2.340

    authors: Nakagawa M,Sato A,Okagawa H,Kondo M,Okuno M,Takamatsu T

    更新日期:1999-08-01 00:00:00

  • Intrathoracic chemothermotherapy following panpleuropneumonectomy for pleural dissemination of invasive thymoma.

    abstract::We report a case of pleural dissemination of invasive thymoma, which was successfully treated with intrathoracic chemothermotherapy following panpleuropneumonectomy. Intrathoracic chemothermotherapy in combination with surgery may be a hopeful adjuvant treatment to control pleural disseminated lesions of invasive thym...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.105.6.1884

    authors: Higashiyama M,Doi O,Kodama K,Yokouchi H

    更新日期:1994-06-01 00:00:00

  • APACHE II in surgical lung carcinoma patients.

    abstract::Recent extensive development of thoracic surgery meets the need to treat elderly patients with a wide variety of pathophysiologic alterations, even if they require continuous medical assistance and high technologic support. Methods in providing such care are still limited by imprecision in evaluation of results; in th...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.3.627

    authors: Giangiuliani G,Gui D,Bonatti P,Tozzi P,Caracciolo F

    更新日期:1990-09-01 00:00:00

  • Solid or partly solid solitary pulmonary nodules: their characterization using contrast wash-in and morphologic features at helical CT.

    abstract:BACKGROUND:Solitary pulmonary nodule (SPN) evaluation based on analyses of combined wash-in (WI) and washout (WO) values obtained by helical dynamic CT (HDCT) scanning is useful for malignant SPN characterization, because this method has higher specificity and accuracy than that based on analyses of WI values only. How...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.06-2526

    authors: Lee KS,Yi CA,Jeong SY,Jeong YJ,Kim S,Chung MJ,Kim HY,Kim YK,Lee KH

    更新日期:2007-05-01 00:00:00

  • Patent ductus arteriosus with hypoplastic lung.

    abstract::A median sternotomy approach was used for closure of patent ductus arteriosus associated with a hypoplastic right lung. The anterior approach to the left ductus is indicated if left thoracotomy is contraindicated. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.69.6.785

    authors: Rao B,Gootman N,Silbert D,Wisoff BG

    更新日期:1976-06-01 00:00:00

  • Bronchoalveolar lavage in extrapulmonary sarcoidosis.

    abstract::Twenty-one patients presenting with extrapulmonary sarcoidosis, 20 patients with pulmonary sarcoidosis, and 12 healthy volunteers were investigated. They were evaluated for roentgenographic findings, as well as for immunologic marker expression of cells in bronchoalveolar lavage (BAL) fluid. The patients presenting wi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.94.1.115

    authors: Hoogsteden HC,van Dongen JJ,Adriaansen HJ,Hooijkaas H,Delahaye M,Hop W,Hilvering C

    更新日期:1988-07-01 00:00:00

  • Medical Education During the COVID-19 Pandemic.

    abstract::All aspects of medical education were affected by the Novel Coronavirus Infectious Disease-19 (COVID-19) pandemic. Several challenges were experienced by trainees and programs alike due to the economic repercussions of the pandemic, how social distancing affected the delivery of medical education, testing and intervie...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2020.12.026

    authors: Kaul V,Gallo de Moraes A,Khateeb D,Greenstein Y,Winter G,Chae J,Stewart NH,Qadir N,Dangayach NS

    更新日期:2020-12-29 00:00:00

  • Preparing for pulmonary resection: preoperative evaluation of patients.

    abstract::Preoperative evaluation of patients being considered for pulmonary resection is a common practice for both pulmonologists and internists. Traditionally, preoperative evaluation of this population has entailed identifying patients in whom pulmonary resection carries an unacceptably high risk of morbidity and mortality....

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.112.4_supplement.206s

    authors: Reilly JJ

    更新日期:1997-10-01 00:00:00

  • Response characteristics of a dual transcutaneous oxygen/carbon dioxide monitoring system.

    abstract::We tested the response characteristics of a dual transcutaneous (tc) PO2/PCO2 monitoring system in healthy subjects who breathed various gas mixtures, and we compared steady-state tc readings to simultaneous arterial blood gas analysis in 20 stable respiratory outpatients. The electrodes were simple to apply, required...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.99.5.1211

    authors: Kesten S,Chapman KR,Rebuck AS

    更新日期:1991-05-01 00:00:00

  • Pulmonary hyperinflation following Nd-YAG laser resection of an obstructing mainstem tumor.

    abstract::Nd-YAG laser resection of a completely obstructing right mainstem tumor in a 36-year-old man was complicated by right lung hyperinflation and left lung collapse and accompanying ventilatory failure. This was attributed to obstruction of the right mainstem bronchus during exhalation, but not inhalation, in a patent but...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.93.6.1302

    authors: Fairfax WR,Rollins RJ

    更新日期:1988-06-01 00:00:00

  • Diaphragmatic motion studied by m-mode ultrasonography: methods, reproducibility, and normal values.

    abstract:BACKGROUND:Although diaphragmatic motion is readily studied by ultrasonography, the procedure remains poorly codified. The aim of this prospective study was to determine the reference values for diaphragmatic motion as recorded by M-mode ultrasonography. METHODS:Two hundred ten healthy adult subjects (150 men, 60 wome...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.08-1541

    authors: Boussuges A,Gole Y,Blanc P

    更新日期:2009-02-01 00:00:00

  • Commonly Used Patient-Reported Outcomes Do Not Improve Prediction of COPD Exacerbations: A Multicenter 4½ Year Prospective Cohort Study.

    abstract:BACKGROUND:Several cross-sectional and short-term studies suggest that patient-reported outcomes (PROs) may be useful to help predict COPD exacerbations, but evidence from long-term prospective cohort studies is lacking. Our aim was to assess if PROs add to the prediction of exacerbations. METHODS:Four hundred eight p...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.chest.2017.09.003

    authors: Strassmann A,Frei A,Haile SR,Ter Riet G,Puhan MA

    更新日期:2017-12-01 00:00:00

  • Ventilation and gas exchange during sleep and exercise in severe COPD.

    abstract::Ventilation and gas exchange were studied during sleep and incremental treadmill exercise in 19 patients with severe stable COPD with the primary aim of comparing the pathophysiology of oxygen desaturation in the two conditions. A secondary aim was to determine whether exercise studies could aid in the prediction of s...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.109.2.387

    authors: Mulloy E,McNicholas WT

    更新日期:1996-02-01 00:00:00

  • The clinical use of lung MRI in cystic fibrosis: what, now, how?

    abstract::To assess airway and lung parenchymal damage non-invasively in cystic fibrosis (CF), chest MRI has been historically out of the scope of routine clinical imaging due to technical difficulties such as the low proton density and respiratory and cardiac motion. However, technological breakthroughs have recently emerged t...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2020.12.008

    authors: Dournes G,Walkup LL,Benlala I,Willmering MM,Macey J,Bui S,Laurent F,Woods JC

    更新日期:2020-12-17 00:00:00

  • Complications of flow-directed balloon-tipped catheters.

    abstract::Acute or short-term complications following the use of flow-directed balloon-tipped catheters are well recognized. Long-term sequelae are rarely reported. We report herein an early complication of pulmonary arterial rupture with infarction followed by the delayed development of a pulmonary arterial aneurysm. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.97.1.227

    authors: Smart FW,Husserl FE

    更新日期:1990-01-01 00:00:00

  • The recrudescent epidemic of retrolental fibroplasia.

    abstract::We are probably observing a recrudescent epidemic of RLF which has elicited surprisingly little attention from the medical community. Given present data, it is not unreasonable to conclude that there is a true epidemic and that its etiologic basis involves a population of infants with high susceptibility to oxygen tox...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.89.4.576

    authors: Robin ED,Burke CM

    更新日期:1986-04-01 00:00:00

  • Comparison of titanium vascular closure staples with suture repair of the thoracic aorta in swine.

    abstract:OBJECTIVE:Devices that reduce technical difficulty and anastigmatic time when repairing large vessels such as the thoracic aorta would be beneficial. The aim of this study was to determine if titanium vascular closure staples (3 mm) could be safely and quickly applied in the repair of large vessels such as the thoracic...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.118.6.1762

    authors: Deb S,Martin B,Sun L,Burris D,Wherry D,Pikoulis E,Rhee P

    更新日期:2000-12-01 00:00:00

  • Sensitivity and specificity of radioisotope right-left shunt measurements and pulse oximetry for the early detection of pulmonary arteriovenous malformations.

    abstract:STUDY OBJECTIVES:To assess the effectiveness of pulse oximetry and radioisotope measurement of right-to-left (R-L) shunt for the early detection of pulmonary arteriovenous malformations (PAVMs) in patients with hereditary hemorrhagic telangiectasia (HHT). DESIGN:Patients with HHT had serial measurements of the followi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.115.1.109

    authors: Thompson RD,Jackson J,Peters AM,Doré CJ,Hughes JM

    更新日期:1999-01-01 00:00:00

  • Increasing renal blood flow: low-dose dopamine or medium-dose norepinephrine.

    abstract:BACKGROUND AND OBJECTIVES:Many clinicians believe that low-dose dopamine (LDD) [2 micro g/kg/min] increases renal blood flow (RBF) and medium-dose norepinephrine (MD-NE) [0.4 micro g/kg/min] decreases RBF. They also believe that MD-NE might induce mesenteric and/or coronary ischemia. In fact, the effects of these drugs...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.125.6.2260

    authors: Di Giantomasso D,Morimatsu H,May CN,Bellomo R

    更新日期:2004-06-01 00:00:00

  • Predictors of time to death after terminal withdrawal of mechanical ventilation in the ICU.

    abstract:BACKGROUND:Little information exists about the expected time to death after terminal withdrawal of mechanical ventilation. We sought to determine the independent predictors of time to death after withdrawal of mechanical ventilation. METHODS:We conducted a secondary analysis from a cluster randomized trial of an end-o...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.10-0289

    authors: Cooke CR,Hotchkin DL,Engelberg RA,Rubinson L,Curtis JR

    更新日期:2010-08-01 00:00:00

  • Thoracoscopy and video-assisted thoracic surgery in the treatment of lung cancer.

    abstract::The contemporary surgical repertoire for the evaluation and treatment of patients with lung cancer includes the bronchoscope, mediastinoscope, thoracoscope, and standard surgical instrumentation. The recent advances in video optics and the development of endoscopic instruments have significantly expanded the surgical ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.107.6_supplement.298s

    authors: Mentzer SJ,DeCamp MM,Harpole DH Jr,Sugarbaker DJ

    更新日期:1995-06-01 00:00:00

  • Bronchiolitis obliterans and Nocardia asteroides infection of the lung.

    abstract::This report describes a patient with right lower lung (RLL) pneumonia of a subacute nature. Sputum and bronchial washings both grew N asteroides. Open lung biopsy showed bronchiolitis obliterans. Both the clinical and radiologic picture dramatically improved during three weeks of treatment with trimethoprim and sulfam...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.6.1107

    authors: Camp M,Mehta JB,Whitson M

    更新日期:1987-12-01 00:00:00

  • Very early onset of acute amiodarone pulmonary toxicity presenting with hemoptysis.

    abstract::A case of amiodarone pulmonary toxicity (APT) occurring within days of the start of therapy and presenting with hemoptysis is reported. Both the very early onset and the presenting symptom are highly unusual in this entity. Implications in the diagnosis of APT are discussed. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.111.5.1446

    authors: Goldstein I,Topilsky M,Segev D,Isakov A,Heller I

    更新日期:1997-05-01 00:00:00

  • Perceptual and physiologic responses during treadmill and cycle exercise in patients with COPD.

    abstract:BACKGROUND:Although the cycle ergometer is the traditional mode for exercise testing in patients with respiratory disease, this preference over the treadmill does not consider perceptual responses. Our hypotheses were as follows: (1) the regression slope between breathlessness and oxygen consumption (Vo(2)) is greater ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.08-1258

    authors: Murray JA,Waterman LA,Ward J,Baird JC,Mahler DA

    更新日期:2009-02-01 00:00:00

  • Endurance exercise in the presence of heart disease.

    abstract::Although patients with heart disease have successfully completed marathon runs, the immediate cardiac effects of similar and greater distance endurance exercise competition are unknown. Two such cases are presented, demonstrating that vigorous exercise and extreme levels of fitness are not precluded in the cardiac pat...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.95.3.697

    authors: Douglas PS,Sigler A,O'Toole ML,Hiller WD

    更新日期:1989-03-01 00:00:00