Abstract:
STUDY OBJECTIVES:We sought to determine the adaptability and effectiveness of a new esophageal balloon technique to measure changes in esophageal pressure (Pes) as a reflection of pleural pressure with progressive incremental exercise testing in normal subjects. DESIGN:An 8F (0.9 cm) esophageal balloon catheter (Smart Cath; Allied Health Products; Riverside, Calif), a CP-100 pulmonary monitor (BiCore Monitoring Systems PC-100; Irvine, Calif), and a flow transducer (Var flex; Allied Health Products; Riverside, Calif) were connected to a breathing valve (model 2700; Hans-Rudolph Inc; Kansas City, Mo). This apparatus was then used to measure Pes during a graded cardiopulmonary exercise test (CPX) to symptom limitation. SETTING:University-affiliated Veterans Affairs Hospital. PARTICIPANTS:Eight nonsmoking volunteers with normal results of pulmonary function tests. INTERVENTIONS:Plots of deltaPes against pressure time product (PTP), minute ventilation (VE), and oxygen consumption (VO2) were obtained. Pes at baseline, anaerobic threshold (AT), and maximum oxygen consumption (VO2max) were obtained by comparing the Pes measurements from the computer printout to the corresponding breath-by-breath measurements on the CPX. MEASUREMENTS AND RESULTS:The flow transducer (Varflex) connection added only 20 mL of dead space to the standard mouthpiece apparatus. The mean maximum work performance was 203+/-32 W. The mean VO2max was 29+/-9 mL/kg/min. The Pes at AT was 16+/-3 cm H2O. The Pes at maximal exercise was 42+/-16 cm H2O. CONCLUSION:The small esophageal balloon was well tolerated by all subjects. Plots of deltaPes vs PTP, VE, and VO2 demonstrated a linear correlation. This apparatus could be added to the standard CPX to assess the contribution of the diaphragm and respiratory muscles in patients with dyspnea.
journal_name
Chestjournal_title
Chestauthors
Thomas AM,Turner RE,Tenholder MFdoi
10.1378/chest.112.3.829subject
Has Abstractpub_date
1997-09-01 00:00:00pages
829-32issue
3eissn
0012-3692issn
1931-3543pii
S0012-3692(16)31755-Xjournal_volume
112pub_type
杂志文章相关文献
CHEST文献大全abstract:INTRODUCTION:Managed care, both via staff model health maintenance plans and nonstaff model plans, has become a major source of health-care funding in the United States. However, very little is known about the asthma-specific products and services offered by these plans. The purpose of this study is to examine the asth...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.suppl_2.173s
更新日期:1999-10-01 00:00:00
abstract::An asymptomatic young man presented with a cardiac murmur and hypertension only in the right arm. Angiograms showed kinking of the aortic arch with a figure-eight appearance consistent with pseudocoarctation. Before the kinked segment, also demonstrated were a stenotic lesion in the aortic arch proximal to the left ca...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.5.1239
更新日期:1990-05-01 00:00:00
abstract::Myiasis refers to a parasitic infestation of vertebrate mammals by dipterous larvae (maggots) of higher flies. Infections in humans typically occur in tropical and subtropical regions, regions with limited medical access, and areas with poor hygiene and living conditions. Infestations in humans have been described in ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2015.12.022
更新日期:2016-06-01 00:00:00
abstract::In order to test the ability of magnetic resonance (MR) in the detection of pathologic flow conditions in man, we imaged 10 normal volunteers and 10 patients with congestive heart failure (CHF) with ECG-gated MR. We used a single spin-echo sequence on a transverse plane through the main vessels of the upper chest. The...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.92.4.645
更新日期:1987-10-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the diagnostic performance of volumetric capnography (VCap), which is the plot of the expired CO(2) partial pressure against the expired volume during a single breath, with the PaCO(2) to end-tidal CO(2) (EtCO(2)) gradient, in the case of suspected pulmonary embolism (PE). DESIGN:Single-cent...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.3.841
更新日期:2004-03-01 00:00:00
abstract::Mitral, aortic, and coronary arterial disease have been described in the various mucopolysaccharidoses. We report the first successful combined aortic and mitral valve replacement in an adult female patient with severe aortic and mitral stenosis due to Scheie's syndrome, a mucopolysaccharide storage disease. Both annu...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.96.1.209
更新日期:1989-07-01 00:00:00
abstract::Pancreaticopleural fistula secondary to chronic pancreatitis is a rare cause of recurrent pleural effusion. The demonstration of the fistula with endoscopic retrograde pancreatography and CT is invasive or limited. We report in two patients the use of magnetic resonance pancreatography as a noninvasive alternative to ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.3.912
更新日期:2000-03-01 00:00:00
abstract::This study was designed to compare the efficacy of coronary thrombolysis obtained with i.v. administration of three dose regimens of recombinant tissue plasminogen activator (rtPA). Although many studies have confirmed the efficacy of thrombolytic therapy in treatment of acute myocardial infarction, few prospective st...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.109.2.510
更新日期:1996-02-01 00:00:00
abstract::Invasive thymoma recently has been shown to be sensitive to combination chemotherapy and in some cases to be relatively indolent. Two cases of extensive thymoma which responded to primary treatment with a combination of a platinum compound (carboplatin or cisplatin), doxorubicin (Adriamycin), and cyclophosphamide (or ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.110.4.1115
更新日期:1996-10-01 00:00:00
abstract::Hospitalizations for patients with acute exacerbations of COPD are associated with several adverse patient outcomes as well as with significant health-care costs. Despite many interventions targeted at reducing readmissions following an initial hospitalization, there are few strategies that have been consistently asso...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1016/j.chest.2019.06.005
更新日期:2019-10-01 00:00:00
abstract::The tendency toward "either/or" thinking (either cure or comfort) in traditional biomedical care paradigms does little to optimize care in advancing chronic illness. Calls for improved palliation in chronic lung disease mandate a review of related care gaps and current clinical practices. Although specialist palliativ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.14-2593
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:The aim of this study was to characterize the practice of routinely obtaining tracheal aspirate cultures in children with tracheostomy tubes and to analyze the appropriateness of using this information to guide antibiotic selection for treatment of subsequent lower respiratory infections. METHODS:Pediatric ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-2539
更新日期:2012-03-01 00:00:00
abstract::A 53-year-old woman with a large pericardial effusion and tamponade presented with signs of IHSS including a grade 4/6 apical systolic murmur, severe SAM, early systolic aortic valve closure and a small hypercontractile left ventricle but at most borderline left ventricular hypertrophy. Following pericardiocentesis, t...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.91.4.631
更新日期:1987-04-01 00:00:00
abstract::Pulmonary sequestration is a congenital anomaly resulting in nonfunctioning lung tissue in either the "extralobar" or "intralobar" position. Both forms derive their blood supply from the systemic circulation. Large pulmonary sequestrations can present in the newborn with potentially fatal respiratory distress. Surgica...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.97.1.244
更新日期:1990-01-01 00:00:00
abstract::The issue of tobacco industry responsibility for population health problems and compensation for their treatment has been growing since the 1960s. In 1999, the state attorneys general collectively launched the largest class action lawsuit in US history and sued the tobacco industry to recover the costs of caring for s...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.09-0982
更新日期:2010-03-01 00:00:00
abstract:STUDY OBJECTIVES:(1) To determine physician preferences in the management of warfarin-induced excessive anticoagulation (AC); and (2) to assess compliance with the American College of Chest Physicians (ACCP) guidelines for the reversal of excessive AC. DESIGN:Cross-sectional physician survey. PARTICIPANTS:Members of ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.6.1972
更新日期:2001-12-01 00:00:00
abstract::We report the findings in a patient with Klippel-Feil syndrome and associated agenesis of right upper and middle lobes, hypoplasia of the right lower lobe of the lung, and Lown-Ganong-Levine syndrome. To our knowledge, such an association has not been previously described. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.4.1157
更新日期:1992-04-01 00:00:00
abstract:STUDY OBJECTIVE:We analyzed the effects of the use of a rollator on walking distance and physiologic variables: pulmonary gas exchange, heart rate, minute ventilation (Ve), oxygen saturation, and symptoms during the 6-min walk test (6MWT) in patients with COPD. SETTING:Outpatient clinic at university hospital. PATIEN...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.126.4.1102
更新日期:2004-10-01 00:00:00
abstract:CASE PRESENTATION:A previously healthy 62-year-old woman was transferred to the ICU from the medical ward with acute bronchospastic respiratory failure requiring intubation and mechanical ventilation. Four weeks before, the patient was vacationing in Arizona and acquired a mildly productive cough as well as mild dyspne...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2017.04.168
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Pleural effusions frequently accumulate in patients with left-sided heart failure. However, our recent study in patients with idiopathic and heritable pulmonary arterial hypertension (PAH) demonstrated that pleural effusions frequently occur in patients with isolated right-sided heart failure (RHF). The obje...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-0227
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Pulmonary exacerbations in cystic fibrosis (CF) contribute to the burden of disease, with a negative impact on quality of life, costs, and lung function. Our aim was to evaluate whether exacerbations, defi ned by antibiotic use, were triggered by daily fl uctuations in air pollution. METHODS:In a case-cross...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.12-1005
更新日期:2013-04-01 00:00:00
abstract:STUDY OBJECTIVES:The management of stable patients with COPD depends on the severity of symptoms and airflow limitation. Regarding inflammation, corticosteroids are the only medications that are recommended for use, and only under restricted circumstances. Corticosteroids tend to undertreat or overtreat patients with C...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.2.375
更新日期:2004-08-01 00:00:00
abstract::Short-course chemotherapy (SCC) for pulmonary tuberculosis for nine months with isoniazid (INH) and rifampin (RIF) is well established. However, there is still no report on results of such therapy in pleural disease. From January 1976 through December 1984, we treated 201 patients (average age 61.6 years) for pleural ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.90.1.112
更新日期:1986-07-01 00:00:00
abstract:BACKGROUND:There is no consensus at the present time about the effect of welding on lung function decline. This study compared lung function decline between blue-collar workers exposed and not exposed to welding fumes in a French longitudinal cohort of 21,238 subjects aged 37 to 52 years at inclusion. METHODS:Medical ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.11-0647
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:There is a growing use of procalcitonin (PCT) to facilitate the diagnosis and management of severe sepsis. We investigated the impact of one to two PCT determinations on ICU day 1 on health-care utilization and cost in a large research database. METHODS:A retrospective, propensity score-matched multivariabl...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2016.06.046
更新日期:2017-01-01 00:00:00
abstract::Mucoid impaction is a complication of asthma and is frequently recurrent in patients with allergic bronchopulmonary aspergillosis (ABPA). This report describes a patient with asthma and recurrent bilateral well-circumscribed densities on chest roentgenogram in the absence of ABPA. Recognition of this clinical presenta...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.4.1023
更新日期:1990-10-01 00:00:00
abstract:BACKGROUND:COPD is a heterogeneous disease characterized by airflow obstruction and diagnosed by lung function. CT imaging is emerging as an important, noninvasive tool in phenotyping COPD. However, the use of CT imaging in defining the disease heterogeneity above lung function is not fully known. METHODS:Seventy-five...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.10-3007
更新日期:2011-09-01 00:00:00
abstract::Patients with cystic fibrosis (CF) and advanced pulmonary disease have pulmonary limitation of exercise, often associated with arterial oxygen desaturation. Improving oxygenation during exercise by providing supplemental oxygen may improve exercise performance in these patients. To test this, we performed graded exerc...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.101.1.52
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Tight glycemic control is recommended for patients in the ICU, as hyperglycemia is associated with increased morbidity and mortality. DESIGN:Observational cohort of patients admitted to a 12-bed, inner-city, medical ICU (MICU). SUBJECTS:A total of 1,185 of 1,506 patients from July 1, 1999, to December 31, ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.5.3109
更新日期:2005-11-01 00:00:00
abstract::Granular cell myoblastoma (GCM) is a rare benign neoplasm involving the tracheobronchial tree. It is believed to arise from the Schwann cell. Four cases of tracheobronchial GCM, all of which were multicentric, are presented and a conservative therapeutic approach is suggested. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.4.945
更新日期:1990-10-01 00:00:00