Optimizing coronary thrombolysis with i.v. administration of recombinant tissue plasminogen activator. Single bolus vs double bolus vs front-loading.

abstract：STUDY OBJECTIVE:To compare the diagnostic performance of volumetric capnography (VCap), which is the plot of the expired CO(2) partial pressure against the expired volume during a single breath, with the PaCO(2) to end-tidal CO(2) (EtCO(2)) gradient, in the case of suspected pulmonary embolism (PE). DESIGN:Single-cent...

journal_title：Chest

authors： Verschuren F,Liistro G,Coffeng R,Thys F,Roeseler J,Zech F,Reynaert M

更新日期：2004-03-01 00:00:00

abstract：STUDY OBJECTIVES:Poor dental hygiene has been linked to respiratory pathogen colonization in residents of long-term care facilities. We sought to investigate the association between dental plaque (DP) colonization and lower respiratory tract infection in hospitalized institutionalized elders using molecular genotyping....

journal_title：Chest

authors： El-Solh AA,Pietrantoni C,Bhat A,Okada M,Zambon J,Aquilina A,Berbary E

更新日期：2004-11-01 00:00:00

abstract：:We retrospectively evaluated the clinical effectiveness of a treatment schedule with intermittent positive pressure ventilation via nasal mask in 49 patients with acute exacerbations of COLD. According to the ability to successfully tolerate a preliminary trial with NIPPV, patients were submitted either to standard tr...

journal_title：Chest

authors： Foglio C,Vitacca M,Quadri A,Scalvini S,Marangoni S,Ambrosino N

更新日期：1992-06-01 00:00:00

abstract：STUDY OBJECTIVES:The objectives of this study are as follows: (1) to determine the incidence of complications from thoracentesis performed under ultrasound guidance by interventional radiologists in a tertiary referral teaching hospital; (2) to evaluate the incidence of vasovagal events without the use of atropine prio...

journal_title：Chest

authors： Jones PW,Moyers JP,Rogers JT,Rodriguez RM,Lee YC,Light RW

更新日期：2003-02-01 00:00:00

abstract：STUDY OBJECTIVES:Acute exposure to the air in swine confinement units causes bronchial hyperresponsiveness and inflammation of the airways. This study was performed to assess the longitudinal development of bronchial responsiveness in pig farmers and to establish exposure-response relationships. METHODS:A cohort of 17...

journal_title：Chest

authors： Vogelzang PF,van der Gulden JW,Folgering H,Heederik D,Tielen MJ,van Schayck CP

更新日期：2000-05-01 00:00:00

abstract：:Simple biopsy resection through the rigid bronchoscope has been described in the past. We successfully performed such resection through a flexible bronchoscope in six patients with symptomatic and relatively less vascular lesions without complications. In selected patients simple biopsy resection of endobronchial lesi...

journal_title：Chest

authors： Mehta AC,Livingston DR

更新日期：1987-05-01 00:00:00

abstract：:At the cardiac sympathetic nerve terminal the alpha 2-adrenoceptor is presynaptic and appears to be located at an extrasynaptic site. This is suggested by (1) absence of evidence of autoinhibitory feedback at physiologic stimulus levels up to about 50 percent of the maximum chronotropic response in the isolated guinea...

journal_title：Chest

authors： Korner PI,Angus JA,Lew MJ,Heinzow BG

更新日期：1983-02-01 00:00:00

abstract：:Respiratory rate is a sensitive clinical parameter in a multitude of pulmonary diseases, especially in the critical care setting. In order to validate the routine recording of the respiratory rate in the intensive care unit, we compared the values obtained from the nursing records with the breathing frequency continuo...

journal_title：Chest

authors： Krieger B,Feinerman D,Zaron A,Bizousky F

更新日期：1986-11-01 00:00:00

abstract：:The measurement of the activity of acid hydrolases and of alkaline phosphatase in bronchial aspirates obtained through bronchoscopic procedures from a series of 300 patients forms the basis for a screening program to diagnose bronchial malignant neoplasms more effectively. We define such a screening test as one permit...

journal_title：Chest

authors： Kühn SH,de Kock MA,Gevers W

更新日期：1978-08-01 00:00:00

abstract：:Histopathologic and morphometric studies of small pulmonary arteries were performed in 16 cases of secundum atrial septal defect (ASD) and severe pulmonary hypertension. Besides typical plexogenic arteriopathies found in six cases, organized microthrombi and what we call "musculoelastosis," that is, proliferation of l...

journal_title：Chest

authors： Yamaki S,Horiuchi T,Miura M,Suzuki Y,Ishizawa E,Takahashi T

更新日期：1986-05-01 00:00:00

abstract：:Beta-2-integrins belong to a family of leukocyte surface glycoproteins that are essential for immune functions of bronchoalveolar cells. The expression of three alpha chains designed as CD11a, CD11b, CD11c, a common beta chain CD18, and of a ligand for several integrins CD54 (ICAM-1) was studied on alveolar macrophage...

journal_title：Chest

authors： Striz I,Wang YM,Kalaycioglu O,Costabel U

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Solitary pulmonary nodule (SPN) evaluation based on analyses of combined wash-in (WI) and washout (WO) values obtained by helical dynamic CT (HDCT) scanning is useful for malignant SPN characterization, because this method has higher specificity and accuracy than that based on analyses of WI values only. How...

journal_title：Chest

authors： Lee KS,Yi CA,Jeong SY,Jeong YJ,Kim S,Chung MJ,Kim HY,Kim YK,Lee KH

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial infarction, and stroke. METHODS:The methods of this guideline f...

journal_title：Chest

authors： Linkins LA,Dans AL,Moores LK,Bona R,Davidson BL,Schulman S,Crowther M

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:To review statistics on smoking prevalence and to analyze whether the implementation of national tobacco control legislation had an association with the prevalence of smoking, and thereby, with the occurrence of smoking-related lung diseases. DESIGN:Smoking prevalence rates (from 1960 to 2000), lung cancer ...

journal_title：Chest

authors： Heloma A,Nurminen M,Reijula K,Rantanen J

更新日期：2004-12-01 00:00:00

abstract：STUDY OBJECTIVE:The aim of this study was to investigate the basal level as well as the tumor necrosis factor (TNF)-alpha- and interferon (IFN)-gamma-induced expression and release of the neutrophil chemoattractants interleukin (IL)-8 and growth-related oncogene (GRO)-alpha in primary bronchial epithelial cells (PBECs)...

journal_title：Chest

authors： Schulz C,Krätzel K,Wolf K,Schroll S,Köhler M,Pfeifer M

更新日期：2004-05-01 00:00:00

abstract：STUDY OBJECTIVE:To use an existing database from a large cohort study with follow-up as long as 5.5 years to assess the extended prognosis of patients who survived their hospitalizations for severe acute respiratory failure (ARF). DESIGN, SETTING, AND PATIENTS:Secondary analysis of an inception cohort of 1,722 patient...

journal_title：Chest

authors： Garland A,Dawson NV,Altmann I,Thomas CL,Phillips RS,Tsevat J,Desbiens NA,Bellamy PE,Knaus WA,Connors AF Jr,SUPPORT Investigators.

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Data on patients with cancer who have a prolonged length of stay (LOS) in the ICU are scarce. The aim of the present study was to evaluate the characteristics and the outcomes of cancer patients with life-threatening complications with an ICU stay > or = 21 days. METHODS:A cohort study performed at a 10-bed...

journal_title：Chest

authors： Soares M,Salluh JIF,Torres VBL,Leal JVR,Spector N

更新日期：2008-09-01 00:00:00

abstract：STUDY OBJECTIVE:The diagnostic value of tumor markers in pleural fluid is subject to debate. The aim of this study was to evaluate the diagnostic performance of several tumor markers in common use for detecting malignant pleural disease. DESIGN:Blinded comparison of four tumor markers in pleural fluid with a confirmat...

journal_title：Chest

authors： Porcel JM,Vives M,Esquerda A,Salud A,Pérez B,Rodríguez-Panadero F

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Combination therapy with inhaled corticosteroids (ICSs) and long-acting beta(2)-agonists (LABAs), or treatment with high doses of ICSs alone improves asthma control when therapy with low-dose ICSs is not sufficient. However, it is not known which of these treatment options is more effective in sustaining ast...

journal_title：Chest

authors： O'Byrne PM,Naya IP,Kallen A,Postma DS,Barnes PJ

更新日期：2008-12-01 00:00:00

abstract：:The adult respiratory distress syndrome (ARDS) is a devastating clinical illness characterized by refractory hypoxemia and high-permeability pulmonary edema. Reactive oxygen species such as hydrogen peroxide and hypochlorous acid may play a key role in the pathogenesis of the acute lung injury. Glutathione (GSH) is a ...

journal_title：Chest

authors： Pacht ER,Timerman AP,Lykens MG,Merola AJ

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:A serum galactomannan (GM) assay has been approved for diagnosing invasive aspergillosis (IA). However, the role of the BAL-GM assay has not been well established. Therefore, we conducted a metaanalysis to determine the overall accuracy of BAL-GM in the diagnosis of IA. METHODS:After a systematic review of ...

journal_title：Chest

authors： Guo YL,Chen YQ,Wang K,Qin SM,Wu C,Kong JL

更新日期：2010-10-01 00:00:00

abstract：:A patient is reported who had Histoplasma capsulatum endocarditis, a rare form of disseminated histoplasmosis. He also had disseminated intravascular coagulopathy and defects in cell-mediated immune responses to Histoplasma antigens. Prompt etiologic diagnosis was made by stain of tissue from a mouth ulcer and confirm...

journal_title：Chest

authors： Bradsher RW,Wickre CG,Savage AM,Harston WE,Alford RH

更新日期：1980-11-01 00:00:00

abstract：:In assessing the effectiveness of lower-limb and upper-limb nonspecific physical training, we have considered 3 objectives in this study: (1) determination of clinical and functional actual state in patients with chronic airway obstruction (CAO), before and after training; (2) determination of the tests, level of work...

journal_title：Chest

authors： Gimenez M,Predine E,Marchand M,Servera E,Ponz JL,Polu JM

更新日期：1992-05-01 00:00:00

abstract：:A 26-year-old man developed coccidioidomycosis which resulted in myocarditis associated with congestive heart failure. A pericardial effusion developed and progressed to constrictive pericarditis. A pericardiectomy was performed and revealed that the pericarditis was due to Coccidioides immitis. The patient was subseq...

journal_title：Chest

authors： Schwartz EL,Waldmann EB,Payne RM,Goldfarb D,Kinard SA

更新日期：1976-11-01 00:00:00

abstract：:The eosinophil count and concentrations of eosinophil cationic protein (ECP) were measured in bronchoalveolar lavage fluid (BALF) from patients with idiopathic pulmonary fibrosis (IPF), pulmonary fibrosis associated with a collagen vascular disorder (PF-CVD), sarcoidosis, and healthy controls. The patients with IPF an...

journal_title：Chest

authors： Fujimoto K,Kubo K,Yamaguchi S,Honda T,Matsuzawa Y

更新日期：1995-07-01 00:00:00

abstract：:Imaging and Doppler echocardiography permits assessment of right ventricular size and systolic function and of pulmonary arterial pressures, and it may facilitate detection of thromboemboli within the heart or pulmonary artery. In patients with acute pulmonary embolism of sufficient severity to appreciably increase ri...

journal_title：Chest

authors： Come PC

更新日期：1992-04-01 00:00:00

abstract：:Bronchopulmonary Kaposi's sarcoma (KS) occurs in 20 percent of AIDS patients with cutaneous involvement; however, complete endobronchial occlusion is uncommon. Moreover, bronchopulmonary KS is infrequent in the absence of cutaneous manifestations. We report a case of documented complete endobronchial obstruction by KS...

journal_title：Chest

authors： Chin R Jr,Jones DF,Pegram PS,Haponik EF

更新日期：1994-05-01 00:00:00

abstract：:We carried out a medical and environmental survey to evaluate respiratory disease at two tungsten carbide (TC) production plants. The study population of 290 subjects (19.2 percent of the total work force) was chosen to focus on those with the greatest potential exposures to cobalt, a binding agent which is probably t...

journal_title：Chest

authors： Sprince NL,Chamberlin RI,Hales CA,Weber AL,Kazemi H

更新日期：1984-10-01 00:00:00

abstract：:Previously, we have reported in 1990 that 35% of carmustine treated patients (6 of 17) who survived childhood brain tumors died of pulmonary fibrosis between 2 and 13 years after treatment. In addition, 8 patients studied in 1989 (13 to 17 years post treatment), had physiologic and biopsy or radiologic evidence of pul...

journal_title：Chest

authors： O'Driscoll BR,Kalra S,Gattamaneni HR,Woodcock AA

更新日期：1995-05-01 00:00:00

abstract：STUDY OBJECTIVES:Prior to the availability of the oral endothelin antagonist bosentan, most patients with pulmonary arterial hypertension (PAH) were treated with continuously infused prostacyclins. Many patients receiving prostacyclins would have received bosentan if it had been available at the time of their diagnosis...

journal_title：Chest

authors： Suleman N,Frost AE

更新日期：2004-09-01 00:00:00