Abstract:
:A patient is reported who had Histoplasma capsulatum endocarditis, a rare form of disseminated histoplasmosis. He also had disseminated intravascular coagulopathy and defects in cell-mediated immune responses to Histoplasma antigens. Prompt etiologic diagnosis was made by stain of tissue from a mouth ulcer and confirmed by culture of the organism from blood. An echocardiogram compared to a previous normal echocardiogram indicated changes consistent with a vegetation. Histologic examination of the resected valve demonstrated organisms. Amphotericin B administration (3.4 g) plus an aortic valve replacement resulted in cure.
journal_name
Chestjournal_title
Chestauthors
Bradsher RW,Wickre CG,Savage AM,Harston WE,Alford RHdoi
10.1378/chest.78.5.791subject
Has Abstractpub_date
1980-11-01 00:00:00pages
791-5issue
5eissn
0012-3692issn
1931-3543pii
S0012-3692(16)31124-2journal_volume
78pub_type
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