Clinical significance of a multiple biomarker assay in patients with lung cancer. A study with logistic regression analysis.

abstract：:Ventilator-associated pneumonia (VAP), a major cause of ICU infection, results in high morbidity, mortality, and health-care costs. Multiple risk factors for VAP involve complex host factors and ubiquitous pathogens that require several different types of prevention strategies. Prevention efforts should focus on reduc...

journal_title：Chest

authors： Craven DE

更新日期：2006-07-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the safety and efficacy of sitaxsentan, an endothelin-A receptor antagonist, in a 12-week, open-label trial of patients with pulmonary arterial hypertension (PAH). PATIENTS:Six children and 14 adults with New York Heart Association (NYHA) functional class II, III, or IV primary pulmonary h...

journal_title：Chest

authors： Barst RJ,Rich S,Widlitz A,Horn EM,McLaughlin V,McFarlin J

更新日期：2002-06-01 00:00:00

abstract：:To study the effects of upper mantle radiation therapy on pulmonary function, forced expiratory volume in one second (FEV1), vital capacity (VC), inspiratory capacity (IC), diffusing capacity for CO (DLCO) and diffusion per unit of alveolar volume (DL/VA were determined in 28 patients with Hodgkin's disease, stages 1-...

journal_title：Chest

authors： do Pico GA,Wiley AL Jr,Rao P,Dickie HA

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Little is known about factors determining the pathogenesis and severity of asthma in Latin American countries. Costa Rica, one of the most prosperous Latin American nations, has a very high asthma prevalence. OBJECTIVE:To examine the relation between potential risk factors and childhood asthma in Costa Rica...

journal_title：Chest

authors： Celedón JC,Soto-Quiros ME,Silverman EK,Hanson L,Weiss ST

更新日期：2001-09-01 00:00:00

abstract：STUDY OBJECTIVES:We investigated the role of two leukotriene B4 (LTB4) receptors, BLT1 and peroxisome proliferator-activated receptor (PPAR)-alpha, in conferring the susceptibility to develop COPD in smokers. Proinflammatory LTB4 activities are mediated by BLT1, while the inactivation of LTB4 is promoted by PPARalpha. ...

journal_title：Chest

authors： Marian E,Baraldo S,Visentin A,Papi A,Saetta M,Fabbri LM,Maestrelli P

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The ratio of FVC to slow inspiratory vital capacity (SVC) has been reported to reflect small airways obstruction, but its validity as such is still unclear. The aim of this study was to assess the applicability of the FVC/SVC ratio as a marker of small airways function in patients with bronchiolitis oblitera...

journal_title：Chest

authors： Cohen J,Postma DS,Vink-Klooster K,van der Bij W,Verschuuren E,Ten Hacken NH,Koëter GH,Douma WR

更新日期：2007-10-01 00:00:00

abstract：:In patients with chronic obstructive pulmonary disease (COPD) studied at rest, nifedipine releases hypoxic pulmonary vasoconstriction (HPV) and worsens gas exchange. During exercise, this drug lowers pulmonary hypertension, but the effects of this lower pulmonary vascular tone on ventilation-perfusion (VA/Q) relations...

journal_title：Chest

authors： Agustí AG,Barberá JA,Roca J,Wagner PD,Guitart R,Rodriguez-Roisín R

更新日期：1990-02-01 00:00:00

abstract：:To clarify changes in beta-adrenergic receptor (BAR) density in spontaneously occurring acute asthma, BAR binding studies were performed on peripheral blood lymphocytes in eight asthmatic and ten normal subjects. Spirometry also was performed. Maximum binding capacity (Bmax) of BAR in acute asthma was significantly lo...

journal_title：Chest

authors： Hataoka I,Okayama M,Sugi M,Inoue H,Takishima T,Shirato K

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:Choices of pharmacologic therapies for pulmonary arterial hypertension (PAH) are ideally guided by high-level evidence. The objective of this guideline is to provide clinicians advice regarding pharmacologic therapy for adult patients with PAH as informed by available evidence. METHODS:This guideline was bas...

journal_title：Chest

authors： Taichman DB,Ornelas J,Chung L,Klinger JR,Lewis S,Mandel J,Palevsky HI,Rich S,Sood N,Rosenzweig EB,Trow TK,Yung R,Elliott CG,Badesch DB

更新日期：2014-08-01 00:00:00

abstract：:Fifteen patients (range of ages, 18 to 35 years) who survived an acute episole of the adult respiratory distress syndrome caused by mechanical or thermal injuries, sepsis, and shock were studied during 1 to 30 months after recovery. The patients had had no previous pulmonary diseases, and only two had been smokers. Al...

journal_title：Chest

authors： Yahav J,Lieberman P,Molho M

更新日期：1978-09-01 00:00:00

abstract：:A bird fancier who had only been exposed to native birds, mostly owls, developed a sever hypersensitivity pneumonitis with a very insidious onset. ...

journal_title：Chest

authors： Kokkarinen J,Tukiainen H,Seppä A,Terho EO

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:In COPD, a decreased inspiratory capacity to total lung capacity ratio (IC/TLC) is associated with dynamic hyperinflation and poor exercise capacity. The association with upper-extremity force measured by handgrip strength (HGS) and 6-min walk distance (6MWD) has not been previously described. We hypothesize...

journal_title：Chest

authors： Felipe C,Bartolome C,Miguel D,Victor PP

更新日期：2015-10-01 00:00:00

abstract：:The gas exchange and hemodynamics were evaluated before, during, and after a two-hour period of prone position in 13 moderate-severe ARDS patients. Lung computerized tomography was obtained in both the supine and prone positions in two of these patients. Average arterial oxygenation improved after prone positioning (p...

journal_title：Chest

authors： Langer M,Mascheroni D,Marcolin R,Gattinoni L

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension, which is related to right ventricular (RV) failure, indicates a poor prognosis in heart failure (HF). Increased ventilatory response and exercise oscillatory ventilation (EOV) also have a negative impact. We hypothesized that the severity classification of HF and risk prediction could...

journal_title：Chest

authors： Guazzi M,Naeije R,Arena R,Corrà U,Ghio S,Forfia P,Rossi A,Cahalin LP,Bandera F,Temporelli P

更新日期：2015-07-01 00:00:00

abstract：:Seventy-two consecutive adult asthmatic patients seen in the Pulmonary Clinic at Rhode Island Hospital were tested for atopy by prick test with 14 standard aeroallergens and by in vitro total and specific IgE determinations (FAST). A total of 58.3 percent of patients were found to be atopic by these tests. There was a...

journal_title：Chest

authors： Kalliel JN,Goldstein BM,Braman SS,Settipane GA

更新日期：1989-12-01 00:00:00

abstract：:Preclinical studies indicate that allogeneic human mesenchymal stem cells (MSC) may be useful for the treatment of several clinical disorders, including sepsis, acute renal failure, acute myocardial infarction, and more recently, acute lung injury (ALI). This article provides a brief review of the biologic qualities o...

journal_title：Chest

authors： Matthay MA,Thompson BT,Read EJ,McKenna DH Jr,Liu KD,Calfee CS,Lee JW

更新日期：2010-10-01 00:00:00

abstract：:Congenital subclavian steal consists of atresia of the proximal end of the subclavian artery, while the blood supply to the distal portion of the subclavian artery originates from the circle of Willis. It should be suspected in complicated malformations of the heart associated with marked hypoplasia or interruption of...

journal_title：Chest

authors： Garcia O,Wilkins R,Cunha D,Jesse MJ

更新日期：1975-03-01 00:00:00

abstract：:Two patients receiving positive pressure ventilation experienced marked gaseous abdominal distension. Analysis of gases from the stomach, ventilator, and room air suggested that the gastric gases came from the ventilator in one patient. The diagnosis of tracheoesophageal fistula was confirmed by esophagoscopy. Analysi...

journal_title：Chest

authors： Kovitz KL,Siebens A,Brower RG

更新日期：1993-08-01 00:00:00

abstract：:Acute hypoxemic respiratory failure (AHRF) can result from diverse lung insults. Toxic oxygen metabolites have been implicated in this clinical condition and in animal models of pulmonary edema. Hydrogen peroxide (H2O2), an oxygen metabolite, mediates tissue injury. We measured H2O2 levels by a spectrophotometric tech...

journal_title：Chest

authors： Sznajder JI,Fraiman A,Hall JB,Sanders W,Schmidt G,Crawford G,Nahum A,Factor P,Wood LD

更新日期：1989-09-01 00:00:00

abstract：:We present an unusual case of a patient with chronic hepatitis C who experienced dyspnea, fever, and cough after 2 1/2 months' treatment with interferon. His radiograph demonstrated diffuse pulmonary infiltrates and bronchoalveolar lavage fluid showed an increase in lymphocytes, especially CD8-positive cells. The lung...

journal_title：Chest

authors： Ogata K,Koga T,Yagawa K

更新日期：1994-08-01 00:00:00

abstract：:Sixty-eight patients with tricuspid atresia were seen at Indiana University during the past 30 years. Long term survivors treated without operation emerged from our review. In these, there was a combination of tricuspid atresia and transposition of the great vessels. ...

journal_title：Chest

authors： Shariatzadeh AN,King H,Girod D,Shumacker HB

更新日期：1977-04-01 00:00:00

abstract：:Twelve adult patients with ostium primum atrial septal defects (incomplete endocardial cushion defect) who underwent surgical repair of their lesions were evaluated in the late postoperative period. All had closure of the low-lying atrial septal defect, with suturing of the mitral valve cleft in 11 patients. Although ...

journal_title：Chest

authors： Goodman DJ,Harrison DC,Schroeder JS

更新日期：1975-02-01 00:00:00

abstract：:Angiosarcoma in the lung is an uncommon disorder and is usually attributable to metastasis from a primary site. Primary pulmonary angiosarcoma is extremely rare, and the prognosis of affected individuals is dismal, with most patients dying within months of presentation. Indeed, there have been no reported instances of...

journal_title：Chest

authors： Kojima K,Okamoto I,Ushijima S,Yoshinaga T,Kitaoka M,Suga M,Sasaki Y

更新日期：2003-12-01 00:00:00

abstract：:We describe a case of unsuspected infrahepatic interruption of the inferior vena cava with hemiazygos continuation in a 67-year-old man presenting with chest pain and evidence of mitral regurgitation. He had no persistent superior vena cava, with the hemiazygos draining directly into the right superior vena cava. Poly...

journal_title：Chest

authors： Dellavalle A,Ribichini F,Steffenino G

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Altitude-induced pulmonary hypertension has been suggested to cause left ventricular (LV) diastolic dysfunction due to ventricular interaction. In this study, we evaluate the effects of exercise- and altitude-induced increase in pulmonary artery pressures on LV diastolic function in an interventional setting...

journal_title：Chest

authors： Bernheim AM,Kiencke S,Fischler M,Dorschner L,Debrunner J,Mairbäurl H,Maggiorini M,Brunner-La Rocca HP

更新日期：2007-08-01 00:00:00

abstract：STUDY OBJECTIVES:Direct current (DC) shocks to the heart cause morphologic and functional myocardial damage. Previous studies have suggested that acute DC shock injury is free radical mediated and that the administration of antioxidant enzymes superoxide dismutase and catalase can reduce the level of DC shock-induced f...

journal_title：Chest

authors： Pagan-Carlo LA,Garcia LA,Hutchison JL,Buettner GR,Kerber RE

更新日期：1999-08-01 00:00:00

abstract：:Nd-YAG laser resection of a completely obstructing right mainstem tumor in a 36-year-old man was complicated by right lung hyperinflation and left lung collapse and accompanying ventilatory failure. This was attributed to obstruction of the right mainstem bronchus during exhalation, but not inhalation, in a patent but...

journal_title：Chest

authors： Fairfax WR,Rollins RJ

更新日期：1988-06-01 00:00:00

abstract：:The effects of six weeks of threshold pressure inspiratory muscle training (IMT) on inspiratory muscle performance, breathing pattern and exercise performance were studied in eight patients with severe airflow obstruction. The results indicated that IMT improved inspiratory muscle performance but did not affect exerci...

journal_title：Chest

authors： Flynn MG,Barter CE,Nosworthy JC,Pretto JJ,Rochford PD,Pierce RJ

更新日期：1989-03-01 00:00:00

abstract：:A 77-year-old man with a history of renal cell carcinoma presented with orthostatic syncope. Investigation revealed metastatic carcinoma in the left lung extending through the pulmonary veins into the left atrium obstructing the mitral orifice. On review of the literature, this case appears to be the first to describe...

journal_title：Chest

authors： Fogel RI,Balady GJ,Klein MD,Rajaii-Khorasani A

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Empirical therapy has been recommended as an initial clinical approach for treating gastroesophageal reflux-induced chronic cough (GERC). This study compared the predictive accuracy of the Gastroesophageal Reflux Disease Questionnaire (GerdQ) with the accuracy of multichannel intraluminal impedance pH monito...

journal_title：Chest

authors： Xu X,Chen Q,Liang S,Lv H,Qiu Z

更新日期：2014-06-01 00:00:00