Increased hydrogen peroxide in the expired breath of patients with acute hypoxemic respiratory failure.

abstract：:Systemic lupus erythematosus (SLE) frequently involves the pleura with resultant pleural effusion. Previous studies have reported that detection of antinuclear antibodies (ANA) in pleural fluid using animal tissue as substrate was a sensitive and specific method for distinguishing SLE pleural effusions from other etio...

journal_title：Chest

authors： Khare V,Baethge B,Lang S,Wolf RE,Campbell GD Jr

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:To compare the systemic bioavailability (assessed by cortisol suppression) of high-dose budesonide when given by four inhaler devices and orally. Also studied are the relative systemic potencies of three inhaled steroids (budesonide, fluticasone propionate, and beclomethasone dipropionate) when given by mete...

journal_title：Chest

authors： Wales D,Makker H,Kane J,McDowell P,O'Driscoll BR

更新日期：1999-05-01 00:00:00

abstract：:We studied six patients with type A botulism to determine the degree of initial respiratory compromise and to quantitate the time course and extent of recovery of the ventilatory and upper airway muscles and exercise performance. The VM weakness was identified in all patients early after botulism. Upper airway muscle ...

journal_title：Chest

authors： Wilcox PG,Morrison NJ,Pardy RL

更新日期：1990-09-01 00:00:00

abstract：:The characteristic arteriopathy of primary pulmonary hypertension (PPH) with attendant endothelial dysfunction provides an opportunity for enhanced cellular activation in the lung. Data from many laboratories support the concept of altered eicosanoid metabolism in PPH. Rigorously quantitative measurements of the excre...

journal_title：Chest

authors： Christman BW

更新日期：1998-09-01 00:00:00

abstract：:To determine the efficacy of doxycycline as a pleural sclerosing agent, we examined the outcomes in 31 patients (aged 31 to 87 years) receiving doxycycline (500 to 1,000 mg) through a chest tube for malignant pleural effusions or persistent bronchopleural fistulae. Of the 27 patients with malignant pleural effusions, ...

journal_title：Chest

authors： Heffner JE,Standerfer RJ,Torstveit J,Unruh L

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Chronic tobacco smoke exposure results in a broad range of lung pathologies including emphysema, airway disease and parenchymal fibrosis as well as a multitude of extra-pulmonary comorbidities. Prior work using CT imaging has identified several clinically relevant subgroups of smoking related lung disease, b...

journal_title：Chest

authors： Billatos E,Ash SY,Duan F,Xu K,Romanoff J,Marques H,Moses E,Han MK,Regan EA,Bowler RP,Mason SE,Doyle TJ,San José Estépar R,Rosas IO,Ross JC,Xiao X,Liu H,Liu G,Sukumar G,Wilkerson M,Dalgard C,Stevenson C,Whitney

更新日期：2020-09-16 00:00:00

abstract：STUDY OBJECTIVE:We undertook the present study to investigate the perception of dyspnea (with respect to changes in end-inspiratory and end-expiratory lung volumes), during four different levels of high-intensity constant work rate exercise (CWRE) in patients with severe COPD. DESIGN:Crossover descriptive study with c...

journal_title：Chest

authors： Puente-Maestu L,García de Pedro J,Martínez-Abad Y,Ruíz de Oña JM,Llorente D,Cubillo JM

更新日期：2005-08-01 00:00:00

abstract：:In order to assess the long-term clinical benefits of palliative Nd:YAG laser photoresection, we studied 69 patients with obstructing exophytic tracheobronchial lesions treated with this modality between Oct 25, 1984 and May 8, 1989. In 55 patients, there was greater than 75 percent restoration of the luminal caliber ...

journal_title：Chest

authors： Ross DJ,Mohsenifar Z,Koerner SK

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The "Dutch hypothesis" suggests that asthma and COPD have common genetic determinants. The serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) gene previously has been associated with COPD. We sought to determine whether SERPINE2 is associated with asthma ...

journal_title：Chest

authors： Himes BE,Klanderman B,Ziniti J,Senter-Sylvia J,Soto-Quiros ME,Avila L,Celedón JC,Lange C,Mariani TJ,Lasky-Su J,Hersh CP,Raby BA,Silverman EK,Weiss ST,DeMeo DL

更新日期：2011-09-01 00:00:00

abstract：:Oxygen therapy is an integral part of the treatment of critically ill patients. Maintenance of adequate oxygen delivery to vital organs often requires the administration of supplemental oxygen, sometimes at high concentrations. Although oxygen therapy is lifesaving, it may be associated with deleterious effects when a...

journal_title：Chest

authors： Budinger GRS,Mutlu GM

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To determine the degree to which bioactive penicillin, metronidazole, ceftriaxone, clindamycin, vancomycin, and gentamicin penetrate into empyemic pleural fluid using our new rabbit model of empyema. METHODS:An empyema was created via the intrapleural injection of 10(8)()Pasteurella multocida bacteria into t...

journal_title：Chest

authors： Teixeira LR,Sasse SA,Villarino MA,Nguyen T,Mulligan ME,Light RW

更新日期：2000-06-01 00:00:00

abstract：STUDY OBJECTIVES:To investigate intracranial pressure (ICP) changes and their mechanisms in chronic hypercapnia. DESIGN:After 12 male Wistar rats were maintained in CO2-mixed air (mean PaCO2, 71.0 mm Hg) for 21 weeks, their ICP levels were measured during the breathing of 0, 5, 10, 12, and 14% CO2-mixed air before and...

journal_title：Chest

authors： Kondo T,Kumagai M,Takei F,Ohta Y

更新日期：1999-05-01 00:00:00

abstract：STUDY OBJECTIVES:Whereas pulmonary rehabilitation reduces symptoms and improves the quality of life of patients with COPD and is recommended in management guidelines, few patients have access to rehabilitation services. The purpose of this study was to investigate the effectiveness of increasing access to selected comp...

journal_title：Chest

authors： Coultas D,Frederick J,Barnett B,Singh G,Wludyka P

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:We evaluated the association between hemodynamic parameters of chronic congestive heart failure (CHF) and mediastinal lymphadenopathy (MLA) in heart transplantation (HT) candidates and the effect of HT on MLA. We also described the results of lymph node (LN) biopsies of MLA in the patients. METHODS:Patients...

journal_title：Chest

authors： Pastis NJ Jr,Van Bakel AB,Brand TM,Ravenel JG,Gilbert GE,Silvestri GA,Judson MA

更新日期：2011-06-01 00:00:00

abstract：:This report describes three cases of massive mobile right heart thrombus and reviews the available literature to better define the pathophysiology, natural history and most appropriate therapy of the syndrome. The clinical presentation of most patients has been severe cardiopulmonary dysfunction and the diagnosis has ...

journal_title：Chest

authors： Crowell RH,Adams GS,Koilpillai CJ,McNutt EJ,Montague TJ

更新日期：1988-12-01 00:00:00

abstract：:Each of 100 chest radiographs selected randomly from a hospital population were read by five experienced radiologists. The films were rich in abnormal findings. Disagreement analysis was performed considering the entire content of the interpretation. The disagreements were graded by a panel as to type (false negative,...

journal_title：Chest

authors： Herman PG,Gerson DE,Hessel SJ,Mayer BS,Watnick M,Blesser B,Ozonoff D

更新日期：1975-09-01 00:00:00

abstract：:Acute left ventricular (LV) dysfunction is common in the critical care setting and more frequently affects the elderly and patients with comorbidities. Because of increased mortality and the potential for significant improvement with early revascularization, the practitioner must first consider acute coronary syndrome...

journal_title：Chest

authors： Chockalingam A,Mehra A,Dorairajan S,Dellsperger KC

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The synthetic peptide solnatide is a novel pharmacologic agent that reduces extravascular lung water, blunts reactive oxygen species production, and improves lung function due to its ability to directly activate the epithelial sodium channel. The goal of this study was to investigate the effect of solnatide ...

journal_title：Chest

authors： Zhou Q,Wang D,Liu Y,Yang X,Lucas R,Fischer B

更新日期：2017-03-01 00:00:00

abstract：STUDY OBJECTIVES:Inspiratory capacity (IC) has been proposed as a simple method to assess acute changes in functional residual capacity (FRC) with bronchodilation, assuming that total lung capacity (TLC) is unchanged. This assumption is based on studies using body plethysmography, which may not accurately measure TLC i...

journal_title：Chest

authors： Duranti R,Filippelli M,Bianchi R,Romagnoli I,Pellegrino R,Brusasco V,Scano G

更新日期：2002-12-01 00:00:00

abstract：:In patients with acquired or congenital heart diseases, the systolic pulmonary artery pressure (PAPs) can be predicted using continuous-wave Doppler ultrasound (CWD) measurement of the peak velocity of a tricuspid regurgitation (TR) jet. The aim of this study was to determine whether CWD could be used to accurately es...

journal_title：Chest

authors： Laaban JP,Diebold B,Zelinski R,Lafay M,Raffoul H,Rochemaure J

更新日期：1989-12-01 00:00:00

abstract：:Health systems confronting the coronavirus disease 2019 (COVID-19) pandemic must plan for surges in ICU demand and equitably distribute resources to maximize benefit for critically ill patients and the public during periods of resource scarcity. For example, morbidity and mortality could be mitigated by a proactive re...

journal_title：Chest

authors： Prekker ME,Brunsvold ME,Bohman JK,Fischer G,Gram KL,Litell JM,Saavedra-Romero R,Hick JL

更新日期：2020-08-01 00:00:00

abstract：:Relapsing polychondritis (RP) is a rare disease characterized by recurrent inflammation and destruction of the cartilaginous structures. Tracheobronchial chondritis is a dreaded complication of RP. We wish to report a case of RP of the trachea and bronchi which was treated with nasal continuous positive airway pressur...

journal_title：Chest

authors： Adliff M,Ngato D,Keshavjee S,Brenaman S,Granton JT

更新日期：1997-12-01 00:00:00

abstract：:Bronchial thermoplasty (BT) involves the application of radiofrequency energy to visible proximal airways to selectively ablate airway smooth muscle. BT is the first nonpharmacologic interventional therapy approved by the US Food and Drug Administration (FDA) for severe asthma. This approval was based on the results o...

journal_title：Chest

authors： Iyer VN,Lim KG

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To ascertain the differences in smoking characteristics between a group of smokers with COPD and another group of healthy smokers, both of which were identified in a population-based epidemiologic study. DESIGN AND PARTICIPANTS:This is an epidemiologic, multicenter, population-based study conducted in seven ...

journal_title：Chest

authors： Jiménez-Ruiz CA,Masa F,Miravitlles M,Gabriel R,Viejo JL,Villasante C,Sobradillo V

更新日期：2001-05-01 00:00:00

abstract：:The incidence of distal esophageal adenocarcinoma and primary proximal gastric carcinoma has increased substantially in the past 15 years, particularly in North America and in some European countries. Patients with curatively resected cancer consistently have a 10 to 20% 5-year survival rate. Radiation therapy alone s...

journal_title：Chest

authors： Ajani JA

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Clinicians lack a validated tool for risk stratification in acute exacerbations of COPD (AECOPD). We sought to validate the BAP-65 (elevated BUN, altered mental status, pulse > 109 beats/min, age > 65 years) score for this purpose. METHODS:We analyzed 34,699 admissions to 177 US hospitals (2007) with either...

journal_title：Chest

authors： Shorr AF,Sun X,Johannes RS,Yaitanes A,Tabak YP

更新日期：2011-11-01 00:00:00

abstract：STUDY OBJECTIVE:To reevaluate whether it is possible to reliably differentiate malignant mediastinal lymph nodes from benign nodes by size, and to determine the frequency of metastases to normal-sized mediastinal lymph nodes that directly affects the sensitivity for detecting malignant mediastinal lymph nodes (N2 nodes...

journal_title：Chest

authors： Arita T,Matsumoto T,Kuramitsu T,Kawamura M,Matsunaga N,Sugi K,Esato K

更新日期：1996-10-01 00:00:00

abstract：:Ten patients undergoing pneumonectomy were evaluated with the lateral position test (LPT) in addition to routine pulmonary function tests (PFTs). On the basis of the percentage of ventilation estimated to be contributed by each lung on LPT, predictions were made for expected values for each patient's post-pneumonectom...

journal_title：Chest

authors： Walkup RH,Vossel LF,Griffin JP,Proctor RJ

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Airway inflammation is important in the development and progression of asthma. Activation of inflammatory cells induces a respiratory burst resulting in the production of reactive oxygen species, such as H(2)O(2). The aim of this study was to measure the concentration of H(2)O(2) in exhaled breath condensate...

journal_title：Chest

authors： Emelyanov A,Fedoseev G,Abulimity A,Rudinski K,Fedoulov A,Karabanov A,Barnes PJ

更新日期：2001-10-01 00:00:00

abstract：KEY POINTS:1. Historically, medical ethics focused on the proper conduct of physicians as members of a profession. 2. Bioethics has emerged as a distinct field over the past several decades and has a broader scope than traditional medical ethics. The field of bioethics includes research ethics, public health ethics, or...

journal_title：Chest

authors： Carrese JA,Sugarman J

更新日期：2006-12-01 00:00:00