Mid-systolic sound associated with aortic insufficiency and bisferiens pulse.

abstract：BACKGROUND:Children with Down syndrome (DS) are at high risk for OSA. Increasing elevation is known to exacerbate underlying respiratory disorders and worsen sleep quality in people without DS, but whether altitude modulates the severity of OSA in DS is uncertain. In this study, we evaluate the impact of elevation (≤ 1...

journal_title：Chest

authors： Jensen KM,Sevick CJ,Seewald LAS,Halbower AC,Davis MM,McCabe ERB,Kempe A,Abman SH

更新日期：2015-05-01 00:00:00

abstract：:Fever, dyspnea, dry cough and interstitial fibrosis occurred in a man with prostate carcinoma treated with nilutamide and buserelin for two and one-half months. The diagnosis of drug-induced fibrosis was established on the basis of chronologic and semiologic events. This is the first such case reported. ...

journal_title：Chest

authors： Seigneur J,Trechot PF,Hubert J,Lamy P

更新日期：1988-05-01 00:00:00

abstract：:To facilitate the studies in cell biology and drug sensitivity of non-small cell lung cancer, cell samples from 55 patients have been used to establish cell lines in culture using a chemically defined medium (ACL-4). A total of 20 cell lines (36 percent) were directly established and characterized: 14 (44 percent) fro...

journal_title：Chest

authors： Masuda N,Fukuoka M,Takada M,Kudoh S,Kusunoki Y

更新日期：1991-08-01 00:00:00

abstract：:Forty-four patients with newly discovered biopsy-proven pulmonary sarcoidosis in roentgenographic stage II (adenopathy and interstitial abnormalities) who also had abnormal pulmonary function (TLC and/or DCO less than 80 percent predicted) were assigned in alternate sequence to either a daily or alternate day predniso...

journal_title：Chest

authors： Spratling L,Tenholder MF,Underwood GH,Feaster BL,Requa RK

更新日期：1985-11-01 00:00:00

abstract：:OSA is associated with significant adverse outcomes with far-reaching health-care implications. OSA is much more common and severe in patients with Down syndrome (DS) than in the general population, yet there is a striking lack of literature in this area. In this review article, we have summarized the current state of...

journal_title：Chest

authors： Lal C,White DR,Joseph JE,van Bakergem K,LaRosa A

更新日期：2015-02-01 00:00:00

abstract：STUDY OBJECTIVES:To describe the risk factors for the development of and mortality resulting from acute respiratory failure (ARF) in a large patient population. DESIGN:A substudy of a prospective, multicenter, observational cohort study, which was designed to validate the sequential organ failure assessment score. SE...

journal_title：Chest

authors： Vincent JL,Akça S,De Mendonça A,Haji-Michael P,Sprung C,Moreno R,Antonelli M,Suter PM,SOFA Working Group. Sequntial organ failure assessment.

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:There is an increasing demand for home mechanical ventilation (HMV) in patients with chronic respiratory insufficiency. At present, noninvasive ventilation is exclusively initiated in a clinical setting at all four centers for HMV in the Netherlands. In addition to its high societal costs and patient discomf...

journal_title：Chest

authors： van den Biggelaar RJM,Hazenberg A,Cobben NAM,Gaytant MA,Vermeulen KM,Wijkstra PJ

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Continuous administration of aerosolized beta 2-agonists has been suggested as an effective treatment for severe reversible airways disease. To facilitate continuous therapy and avoid a feed system for small-volume nebulizers (SVNs), a large-volume medication nebulizer (Vortran HEART) was deve...

journal_title：Chest

authors： McPeck M,Tandon R,Hughes K,Smaldone GC

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension, which is related to right ventricular (RV) failure, indicates a poor prognosis in heart failure (HF). Increased ventilatory response and exercise oscillatory ventilation (EOV) also have a negative impact. We hypothesized that the severity classification of HF and risk prediction could...

journal_title：Chest

authors： Guazzi M,Naeije R,Arena R,Corrà U,Ghio S,Forfia P,Rossi A,Cahalin LP,Bandera F,Temporelli P

更新日期：2015-07-01 00:00:00

abstract：:The hypothetic benefit of CPAP on cardiac performance and on a reduction in VO2 was tested in a patient before heart transplantation after acute myocardial infarction using continuous SvO2 monitoring. The CPAP added to inotropic support (enoximone plus dobutamine) and intraaortic balloon pumping dramatically increased...

journal_title：Chest

authors： Pery N,Payen D,Pinsky MR

更新日期：1991-02-01 00:00:00

abstract：STUDY OBJECTIVES:The aim of this study was to explore the relationship between quality of life and measures of asthma, such as lung function, reversibility to bronchodilation, exhaled nitric oxide (NO), and bronchial responsiveness to direct and indirect stimulus in patients with mild asthma in a primary care setting. ...

journal_title：Chest

authors： Ehrs PO,Sundblad BM,Larsson K

更新日期：2006-03-01 00:00:00

abstract：:Volatile organic compounds (VOCs) are produced by virtually all metabolic processes of the body. As such, they have potential to serve as noninvasive metabolic biomarkers. Since exhaled VOCs are either derived from the respiratory tract itself or have passed the lungs from the circulation, they are candidate biomarker...

journal_title：Chest

authors： van der Schee MP,Paff T,Brinkman P,van Aalderen WMC,Haarman EG,Sterk PJ

更新日期：2015-01-01 00:00:00

abstract：:Bronchodilator responses to both nebulized albuterol (salbutamol) and ipratropium bromide and aerosol delivery to the tracheobronchial tree have been assessed in eight patients with chronic stable asthma (mean baseline FEV1, 50 percent; reversibility greater than 20 percent). Two commercially available nebulizer syste...

journal_title：Chest

authors： Johnson MA,Newman SP,Bloom R,Talaee N,Clarke SW

更新日期：1989-07-01 00:00:00

abstract：STUDY OBJECTIVES:Salmeterol (S) and montelukast (M) individually inhibit the obstructive consequences of thermal stimuli such as exercise and hyperventilation (HV), but there is no information on whether these drugs can interact positively. DESIGN:Randomized trial. SETTING:University teaching hospital. PARTICIPANTS:...

journal_title：Chest

authors： Coreno A,Skowronski M,West E,El-Ekiaby A,McFadden ER Jr

更新日期：2005-05-01 00:00:00

abstract：:A tracheoesophageal fistula was successfully closed with a fibrin adhesive applied by means of a fiberoptic bronchoscope, instead of by esophagoscopy. To facilitate closure of the fistula, the technique was combined with decontamination of the oral cavity, to avoid bacterial contamination. The procedure is proposed as...

journal_title：Chest

authors： Antonelli M,Cicconetti F,Vivino G,Gasparetto A

更新日期：1991-08-01 00:00:00

abstract：:A CO2 rebreathing method for the measurement of cardiac output was evaluated by comparison with the direct Fick O2 method in 26 studies performed in 18 patients who were critically ill. The method requires measurement of CO2 output by collection of expired gas, of arterial PCO2, and of mixed venous PCO2 by rebreathing...

journal_title：Chest

authors： Davis CC,Jones NL,Sealey BJ

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Glutathione S-transferase (GST) genes are involved in the management of oxidative stress in the lungs. We aimed to determine whether they modify the associations between early life smoke exposure and adverse lung health outcomes. METHODS:The Melbourne Atopy Cohort study (a high-risk birth cohort) enrolled 6...

journal_title：Chest

authors： Dai X,Dharmage SC,Bowatte G,Waidyatillake NT,Perret JL,Hui J,Erbas B,Abramson MJ,Lowe AJ,Burgess JA,Svanes C,Lodge CJ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:COPD has traditionally been defined by the presence of irreversible airflow limitation on spirometry using either the GOLD (Global Initiative for Chronic Obstructive Lung Disease) or American Thoracic Society/European Respiratory Society criteria (lower limit of normal [LLN]). We have observed that some pati...

journal_title：Chest

authors： Lutchmedial SM,Creed WG,Moore AJ,Walsh RR,Gentchos GE,Kaminsky DA

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Linear endobronchial ultrasound (EBUS) allows real-time guidance of transbronchial needle aspiration of thoracic structures and has become an increasingly important diagnostic tool for chest physicians. Little has been published about the learning experience of operators with this technology. The purpose of ...

journal_title：Chest

authors： Wahidi MM,Hulett C,Pastis N,Shepherd RW,Shofer SL,Mahmood K,Lee H,Malhotra R,Moser B,Silvestri GA

更新日期：2014-03-01 00:00:00

abstract：:Selection of patients with lung cancer who are most likely to benefit from chemotherapeutic treatment would be a substantial step forward. Therefore, a prospective study in predictive chemosensitivity testing in vitro using the fast green assay (FGA) as developed by Weisenthal et al was carried out. Sixty-six pretreat...

journal_title：Chest

authors： Smit EF,de Vries EG,Meijer C,Mulder NH,Postmus PE

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Approximately 40% of patients in medical ICUs require mechanical ventilation (MV). Approximately 20% to 25% of these patients will encounter difficulties in discontinuing MV. Multiple studies have suggested that MV has an unloading effect on the respiratory muscles that leads to diaphragmatic atrophy and dys...

journal_title：Chest

authors： Grosu HB,Lee YI,Lee J,Eden E,Eikermann M,Rose KM

更新日期：2012-12-01 00:00:00

abstract：:Unilateral pulmonary edema is a distinctly unusual clinical entity, often misdiagnosed initially as one of the more common causes of focal lung disease. Predominantly lobar pulmonary edema is rarer still. We report a case of right upper lobe pulmonary edema caused by the acute onset of severe mitral regurgitation. In ...

journal_title：Chest

authors： Roach JM,Stajduhar KC,Torrington KG

更新日期：1993-04-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the long-term clinical course of patients with idiopathic pulmonary fibrosis (IPF) complicated with pulmonary arterial hypertension. DESIGN:Prospective analysis of consecutive IPF patients undergoing initial workup with right-heart catheterization (RHC) and pulmonary function testing (PFT)...

journal_title：Chest

authors： Hamada K,Nagai S,Tanaka S,Handa T,Shigematsu M,Nagao T,Mishima M,Kitaichi M,Izumi T

更新日期：2007-03-01 00:00:00

abstract：:The upregulation of nitric oxide (NO) by inflammatory cytokines and mediators in central and peripheral airway sites can be monitored easily in exhaled air. It is now possible to estimate the predominant site of increased fraction of exhaled NO (FeNO) and its potential pathologic and physiologic role in various pulmon...

journal_title：Chest

authors： Barnes PJ,Dweik RA,Gelb AF,Gibson PG,George SC,Grasemann H,Pavord ID,Ratjen F,Silkoff PE,Taylor DR,Zamel N

更新日期：2010-09-01 00:00:00

abstract：:In order to test the ability of magnetic resonance (MR) in the detection of pathologic flow conditions in man, we imaged 10 normal volunteers and 10 patients with congestive heart failure (CHF) with ECG-gated MR. We used a single spin-echo sequence on a transverse plane through the main vessels of the upper chest. The...

journal_title：Chest

authors： Casolo GC,Bucciolini M,Giani M,Bisi G

更新日期：1987-10-01 00:00:00

abstract：:Surfactant replacement therapy (SRT) has a proven role in the treatment of neonatal respiratory distress syndrome and severe meconium aspiration syndrome in infants, and may have a role in the treatment of pediatric patients with ARDS. Although newer delivery mechanisms and strategies are being studied, the classic su...

journal_title：Chest

authors： Stevens TP,Sinkin RA

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:There remains debate over the best invasive diagnostic modality for mediastinal nodal evaluation. Prior studies have limited generalizability and insufficient power to detect differences in rare adverse events. We compared the risks and costs of endobronchial ultrasound (EBUS)-guided nodal aspiration and med...

journal_title：Chest

authors： Verdial FC,Berfield KS,Wood DE,Mulligan MS,Roth JA,Francis DO,Farjah F

更新日期：2020-03-01 00:00:00

abstract：:Irradiation therapy for lung cancer is mostly restricted to conventional methods. To improve therapeutic ratio, we have combined a treatment planning and a gene therapy approach. Three-dimensional conformal radiotherapy is described as carried out by methods of gene therapy for radiation protection using the manganese...

journal_title：Chest

authors： Greenberger JS,Bahri S,Jett J,Belani C,Kalend A,Epperly M

更新日期：1998-01-01 00:00:00

abstract：:Benign thymic hyperplasia (BTH) is a known feature of hyperthyroidism, but is infrequently appreciated by clinicians. In most cases thymic enlargement is minimal; however, it may occasionally present as an appreciable anterior mediastinal mass. While surgical resection is a common approach to such a mass, recognition ...

journal_title：Chest

authors： White SR,Hall JB,Little A

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Unlike studies on leg exercise, reports on the regulation of dynamic hyperinflation during arm exercise are scanty. We ascertained the following in patients with COPD: (1) whether and to what extent upper-limb exercise results in dynamic hyperinflation, and (2) the mechanism whereby an arm-training program (...

journal_title：Chest

authors： Gigliotti F,Coli C,Bianchi R,Grazzini M,Stendardi L,Castellani C,Scano G

更新日期：2005-09-01 00:00:00