Considerations in optimizing radiation therapy for non-small cell lung cancer.

abstract：:A series of 15 patients with life threatening, massive hemoptysis is reported. Thirteen of these patients underwent immediate operative treatment with only three deaths. One died after bronchoscopic identification of the bleeding site while awaiting elective thoracotomy. The other patient left the hospital against med...

journal_title：Chest

authors： McCollun WB,Mattox KL,Guinn GA,Beall AC Jr

更新日期：1975-02-01 00:00:00

abstract：:Research on dominant oncogenes and tumor suppressor genes has characterized differences in genetic lesions between small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) and identified associations with clinical parameters. More than one half of all lung cancers contain a mutation of the p53 tumor suppre...

journal_title：Chest

authors： Johnson BE,Kelley MJ

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:The improved lung deposition of hydrofluoroalkane-134a beclomethasone dipropionate (HFA-BDP) extrafine aerosol compared with chlorofluorocarbon beclomethasone dipropionate (CFC-BDP) suggests that lower doses of HFA-BDP may be required to provide equivalent asthma control. The present study was undertaken to t...

journal_title：Chest

authors： Gross G,Thompson PJ,Chervinsky P,Vanden Burgt J

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Central venous pressure (CVP) is used almost universally to guide fluid therapy in hospitalized patients. Both historical and recent data suggest that this approach may be flawed. OBJECTIVE:A systematic review of the literature to determine the following: (1) the relationship between CVP and blood volume, (...

journal_title：Chest

authors： Marik PE,Baram M,Vahid B

更新日期：2008-07-01 00:00:00

abstract：STUDY OBJECTIVES:To explore the role of respiratory interactive computer games in teaching spirometry to preschool children, and to examine whether the spirometry data achieved are compatible with acceptable criteria for adults and with published data for healthy preschool children, and whether spirometry at this age c...

journal_title：Chest

authors： Vilozni D,Barak A,Efrati O,Augarten A,Springer C,Yahav Y,Bentur L

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Lung cancer is the most common cause of cancer death in the United States. Cigarette smoking is the main risk factor. Former smokers are at a substantially increased risk for lung cancer compared with lifetime never-smokers. Chemoprevention is the use of specific agents to reverse, suppress, or prevent the p...

journal_title：Chest

authors： Gray J,Mao JT,Szabo E,Kelley M,Kurie J,Bepler G,American College of Chest Physicians.

更新日期：2007-09-01 00:00:00

abstract：STUDY OBJECTIVES:The inhalation of hypoxic gas has been reported to enhance the airway responsiveness to methacholine in some animal models. However, the data on humans have so far been conflicting. We attempted to examine the effect of hypoxic gas inhalation on the airway responsiveness to methacholine. DESIGN:We eva...

journal_title：Chest

authors： Saito H,Nishimura M,Shinano H,Sato F,Miyamoto K,Kawakami Y

更新日期：1999-12-01 00:00:00

abstract：:The efficacy of bronchoscopy for the diagnosis of tuberculosis in patients infected with human immunodeficiency virus (HIV) has not been systematically evaluated. We therefore compared the diagnostic yield of bronchoscopy in 67 HIV-infected and 45 non-HIV-infected patients with culture-proven pulmonary tuberculosis. I...

journal_title：Chest

authors： Kennedy DJ,Lewis WP,Barnes PF

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Among patients awaiting cadaveric lung transplantation, patients with idiopathic interstitial pneumonia (IIP) have been demonstrated to have the highest mortality rate. Contraindications to cadaveric lung transplantation include current high-dose systemic corticosteroid therapy because it may increase airway...

journal_title：Chest

authors： Date H,Tanimoto Y,Goto K,Yamadori I,Aoe M,Sano Y,Shimizu N

更新日期：2005-09-01 00:00:00

abstract：:Forty-eight children with known asthma (ranging in age from 2 to 16 years) were studied during an acute attack. Each received either terbutaline or epinephrine subcutaneously in a random double-blind fashion. Measurement of heart rate, respiratory rate, and systemic arterial systolic and diastolic blood pressures and ...

journal_title：Chest

authors： Davis WJ,Pang LM,Chernack WJ,Mellins RB

更新日期：1977-11-01 00:00:00

abstract：:End-tidal CO2 monitors are used to estimate arterial CO2 pressure (PaCO2), but appropriate use of this noninvasive method of assessing blood gases is unclear. In patients with lung disease, the end-tidal CO2 pressure (PETCO2) can differ from PaCO2 because of ventilation-perfusion (VA/Q) mismatching, and changes in PET...

journal_title：Chest

authors： Yamanaka MK,Sue DY

更新日期：1987-11-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the impact on survival and clinical correlates of pulmonary hypertension (PH) occurring in patients with idiopathic pulmonary fibrosis (IPF). DESIGN:Retrospective study. SETTING:Tertiary care, referral medical center. PATIENTS:Among 487 consecutive patients with IPF, we identified 136 p...

journal_title：Chest

authors： Nadrous HF,Pellikka PA,Krowka MJ,Swanson KL,Chaowalit N,Decker PA,Ryu JH

更新日期：2005-10-01 00:00:00

abstract：:Acute hypoxemic respiratory failure (AHRF) can result from diverse lung insults. Toxic oxygen metabolites have been implicated in this clinical condition and in animal models of pulmonary edema. Hydrogen peroxide (H2O2), an oxygen metabolite, mediates tissue injury. We measured H2O2 levels by a spectrophotometric tech...

journal_title：Chest

authors： Sznajder JI,Fraiman A,Hall JB,Sanders W,Schmidt G,Crawford G,Nahum A,Factor P,Wood LD

更新日期：1989-09-01 00:00:00

abstract：:The results of previously published studies indicate that calcium channel blockers are capable of competitively inhibiting cytochrome P-450 activity in hepatic microsomes, the pathway of theophylline metabolism. In addition, case reports have suggested that theophylline serum concentrations change when a calcium chann...

journal_title：Chest

authors： Christopher MA,Harman E,Hendeles L

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:A pulmonary right-to-left shunt (RLS) carries the risk of cerebral paradoxical embolization and severe neurologic complications. Recognizing patients at risk is important to facilitate appropriate management strategies, but a direct relation between pulmonary shunt size and risk of complications remains cont...

journal_title：Chest

authors： Velthuis S,Buscarini E,van Gent MWF,Gazzaniga P,Manfredi G,Danesino C,Schonewille WJ,Westermann CJJ,Snijder RJ,Mager JJ,Post MC

更新日期：2013-08-01 00:00:00

abstract：:In experimental animals, conditions which drastically decrease cardiac output may reduce the strength and endurance of respiratory muscles leading to hypercapnic respiratory failure. Because patients with chronic CHF have reduced cardiac output and vital capacity (FVC), we measured PImax and PEmax and maximal handgrip...

journal_title：Chest

authors： Hammond MD,Bauer KA,Sharp JT,Rocha RD

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVES:To evaluate the additional information provided by pulse transit time (PTT), a noninvasive tool, when using during polysomnography for the diagnosis of sleep breathing disorders in a pediatric population. MAIN FINDINGS:Respiratory and microarousals events were scored twice. The first scoring was performed u...

journal_title：Chest

authors： Pépin JL,Delavie N,Pin I,Deschaux C,Argod J,Bost M,Levy P

更新日期：2005-03-01 00:00:00

abstract：:To clarify changes in beta-adrenergic receptor (BAR) density in spontaneously occurring acute asthma, BAR binding studies were performed on peripheral blood lymphocytes in eight asthmatic and ten normal subjects. Spirometry also was performed. Maximum binding capacity (Bmax) of BAR in acute asthma was significantly lo...

journal_title：Chest

authors： Hataoka I,Okayama M,Sugi M,Inoue H,Takishima T,Shirato K

更新日期：1993-08-01 00:00:00

abstract：:We report a case of pleural dissemination of invasive thymoma, which was successfully treated with intrathoracic chemothermotherapy following panpleuropneumonectomy. Intrathoracic chemothermotherapy in combination with surgery may be a hopeful adjuvant treatment to control pleural disseminated lesions of invasive thym...

journal_title：Chest

authors： Higashiyama M,Doi O,Kodama K,Yokouchi H

更新日期：1994-06-01 00:00:00

abstract：:In this investigation, we examined changes in exfoliated tracheobronchial cells in sputum in 46 individuals (mean age = 49.2 years; mean packyears = 48.7) who discontinued smoking and 37 individuals (mean age = 54.9 years; mean packyears = 65.2) who continued to smoke over a 12-month period after participation in the ...

journal_title：Chest

authors： Swan GE,Hodgkin JE,Roby T,Mittman C,Jacobo N,Peters J

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Little information exists about the expected time to death after terminal withdrawal of mechanical ventilation. We sought to determine the independent predictors of time to death after withdrawal of mechanical ventilation. METHODS:We conducted a secondary analysis from a cluster randomized trial of an end-o...

journal_title：Chest

authors： Cooke CR,Hotchkin DL,Engelberg RA,Rubinson L,Curtis JR

更新日期：2010-08-01 00:00:00

abstract：:A 75-year-old man with a history of resected colon carcinoma presented to his primary care physician because of a new onset of coughing. The patient had expectorated a small piece of solid tissue; pathologic examination of the tissue found it to be consistent with metastatic colon adenocarcinoma. After further work-up...

journal_title：Chest

authors： Zias EA,Owen RP,Borczuk A,Reichel J,Frater RW

更新日期：1998-01-01 00:00:00

abstract：:POC testing provides an opportunity for clinicians and laboratorians to work together to consider how best to serve the patients within an individual institution. Each health system has unique characteristics relative to patient population, as well as a unique laboratory structure. If physicians, nurses, laboratorians...

journal_title：Chest

authors： Kost GJ,Ehrmeyer SS,Chernow B,Winkelman JW,Zaloga GP,Dellinger RP,Shirey T

更新日期：1999-04-01 00:00:00

abstract：STUDY OBJECTIVES:To determine whether the quantitative evaluation of hemomediastinum using transesophageal echocardiography (TEE) is predictive of the presence of a traumatic disruption of the thoracic aorta (TDA) or its branches in patients who have sustained severe blunt chest trauma. DESIGN:Retrospective study. SE...

journal_title：Chest

authors： Vignon P,Rambaud G,François B,Preux PM,Lang RM,Gastinne H

更新日期：1998-06-01 00:00:00

abstract：STUDY OBJECTIVE:To examine the relation between left atrial (LA) function and exercise performance. DESIGN AND SETTING:Retrospective study at a referral cardiopulmonary exercise laboratory in a university hospital. PATIENTS:Forty-one patients with recent myocardial infarction. INTERVENTIONS:M-mode echocardiography a...

journal_title：Chest

authors： Jikuhara T,Sumimoto T,Tarumi N,Yuasa F,Hattori T,Sugiura T,Iwasaka T

更新日期：1997-04-01 00:00:00

abstract：:Long-term treatment with inhaled beta 2-agonists may be associated with a deterioration in asthma control, potentially due to tolerance. Regular use of short-acting beta 2-agonists has been shown to induce tolerance to allergen or adenosine 5'-monophosphate challenge. The aim of the study was to detect the efficacy of...

journal_title：Chest

authors： Giannini D,Carletti A,Dente FL,Bacci E,Di Franco A,Vagaggini B,Paggiaro PL

更新日期：1996-12-01 00:00:00

abstract：:The results of computed chest tomograms (CT) and chest roentgenograms (CR) were compared in 32 patients who presented with hemoptysis. The CT demonstrated roentgenographic abnormalities more often than CR (p less than 0.01), providing new diagnostic information in 15 patients (46.9 percent), and clarifying CR abnormal...

journal_title：Chest

authors： Haponik EF,Britt EJ,Smith PL,Bleecker ER

更新日期：1987-01-01 00:00:00

abstract：:Allergic bronchopulmonary aspergillosis (ABPA) is an immunologic pulmonary disorder caused by hypersensitivity to Aspergillus fumigatus. Clinically, a patient presents with chronic asthma, recurrent pulmonary infiltrates, and bronchiectasis. The population prevalence of ABPA is not clearly known, but the prevalence in...

journal_title：Chest

authors： Agarwal R

更新日期：2009-03-01 00:00:00

abstract：:Familial Mediterranean fever (FMF) is an autosomal recessive disease affecting predominantly populations surrounding the Mediterranean basin. It is the most prevalent hereditary periodic fever syndrome characterized mainly by recurrent and short attacks of fever and serositis (pleuritis, arthritis, peritonitis). Unila...

journal_title：Chest

authors： Katsenos S,Mermigkis C,Psathakis K,Tsintiris K,Polychronopoulos V,Panagou P,Ritis K,Light RW

更新日期：2008-04-01 00:00:00

abstract：:As the actual mortality and morbidity of obstructive sleep apnea syndrome (OSAS) have been unknown heretofore, we undertook a follow-up study of 198 OSAS patients seen at the Stanford Sleep Disorders Clinic between 1972 and 1980, for whom either tracheostomy (71 patients) or weight loss (127 patients) had been recomme...

journal_title：Chest

authors： Partinen M,Jamieson A,Guilleminault C

更新日期：1988-12-01 00:00:00