当前位置： SCI文献检索 > CHEST期刊下所有文献 > Left atrial function as a reliable predictor of exercise capacity in patients with recent myocardial infarction.

Left atrial function as a reliable predictor of exercise capacity in patients with recent myocardial infarction.

Abstract：

STUDY OBJECTIVE:To examine the relation between left atrial (LA) function and exercise performance. DESIGN AND SETTING:Retrospective study at a referral cardiopulmonary exercise laboratory in a university hospital. PATIENTS:Forty-one patients with recent myocardial infarction. INTERVENTIONS:M-mode echocardiography and cardiopulmonary exercise testing combined with radionuclide ventriculography. MEASUREMENTS AND RESULTS:Hemodynamic measurements were obtained at rest and peak exercise. LA fractional shortening at rest was used as an index of global LA function. LA fractional shortening had fair correlations with peak oxygen consumption (r=0.67, p<0.01) and exercise duration (r=0.71, p<0.01). Although there were no significant relations between LA fractional shortening and hemodynamic measurements at rest, LA fractional shortening was positively related to peak cardiac output (r=0.61, p<0.01) and peak stroke volume (r=0.57, p<0.01), and negatively related to peak pulmonary arterial wedge pressure (r=-0.44, p<0.05). In addition, LA fractional shortening correlated significantly with an increase in left ventricular (LV) end-diastolic volume from rest to peak exercise (r=0.48, p<0.02), but did not correlate with the changes in ejection fraction and end-systolic volume during exercise. An increase in LV end-diastolic volume during exercise was significantly related to peak oxygen consumption (r=0.46, p<0.02), peak cardiac output (r=0.60, p<0.01), and peak stroke volume (r=0.53, p<0.01), whereas the changes in ejection fraction and end-systolic volume during exercise were not related to these indexes. CONCLUSIONS:Exercise capacity and LV performance during exercise were mainly dependent on LV diastolic filling rather than systolic contraction during exercise. LA fractional shortening at rest reflected LV diastolic filling during exercise and, therefore, predicted cardiac output and stroke volume responses to exercise and exercise capacity in patients with recent myocardial infarction.

journal_name

Chest

journal_title

Chest

authors

Jikuhara T,Sumimoto T,Tarumi N,Yuasa F,Hattori T,Sugiura T,Iwasaka T

doi

10.1378/chest.111.4.922

subject

Has Abstract

pub_date

1997-04-01 00:00:00

pages

922-8

issue

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)46916-8

journal_volume

111

pub_type

杂志文章

在线工具

Left atrial function as a reliable predictor of exercise capacity in patients with recent myocardial infarction.