Comparison of the effects of salmeterol and formoterol in patients with severe asthma.

abstract：:Twelve adult patients with ostium primum atrial septal defects (incomplete endocardial cushion defect) who underwent surgical repair of their lesions were evaluated in the late postoperative period. All had closure of the low-lying atrial septal defect, with suturing of the mitral valve cleft in 11 patients. Although ...

journal_title：Chest

authors： Goodman DJ,Harrison DC,Schroeder JS

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Substance P and the neurokinin-1 (NK-1) receptor are implicated in chronic refractory cough pathophysiology. We assessed the efficacy and safety of orvepitant, a brain-penetrant NK-1 antagonist, in an open-label study in CRC patients with chronic refractory cough. METHODS:Thirteen patients with daytime coug...

journal_title：Chest

authors： Smith J,Allman D,Badri H,Miller R,Morris J,Satia I,Wood A,K Trower M

更新日期：2020-01-01 00:00:00

abstract：:Over the last few years, there has been a renewed interest in patients with characteristics of both asthma and COPD. Although the precise definition of asthma-COPD overlap (ACO) is still controversial, patients with overlapping features are frequently encountered in clinical practice, and may indeed have worse clinica...

journal_title：Chest

authors： Maselli DJ,Hardin M,Christenson SA,Hanania NA,Hersh CP,Adams SG,Anzueto A,Peters JI,Han MK,Martinez FJ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Spontaneous pneumothorax is a complication that is commonly reported in patients with cystic fibrosis (CF). An understanding of the pathophysiology of this complication and its consequences is important for the management of patients with CF. OBJECTIVE:To identify risk factors associated with pneumothorax a...

journal_title：Chest

authors： Flume PA,Strange C,Ye X,Ebeling M,Hulsey T,Clark LL

更新日期：2005-08-01 00:00:00

abstract：:Mucoid impaction is a complication of asthma and is frequently recurrent in patients with allergic bronchopulmonary aspergillosis (ABPA). This report describes a patient with asthma and recurrent bilateral well-circumscribed densities on chest roentgenogram in the absence of ABPA. Recognition of this clinical presenta...

journal_title：Chest

authors： Anderson WM

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:International guidelines advocate a standard approach to asthma management for all, despite its heterogeneity. "Personalized" treatment of inflammatory asthma phenotypes confers superior benefits. We wished to evaluate dose response to inhaled corticosteroids (ICSs) in patients with asthma with an elevated f...

journal_title：Chest

authors： Anderson WJ,Short PM,Williamson PA,Lipworth BJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:In patients who have experienced acute myocardial infarction (MI), primary percutaneous coronary intervention (PCI) has been shown to be of benefit in terms of clinical outcomes. However, the value of performing routine PCI in patients with early MI (ie, an MI occurring > 12 h to < or = 7 days before patient...

journal_title：Chest

authors： Yip HK,Wu CJ,Yang CH,Chang HW,Chen SM,Hung WC,Hang CL

更新日期：2004-07-01 00:00:00

abstract：:To assess the value of bronchoalveolar lavage (BAL) for diagnosis, understanding, and treatment of amiodarone-associated pneumonitis, we examined the results of BAL total and differential cell counts and phenotyping of lymphocytes in 22 patients with this lung disorder and in 33 normal subjects. Overall, the total cel...

journal_title：Chest

authors： Akoun GM,Cadranel JL,Blanchette G,Milleron BJ,Mayaud CM

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:In a rodent model of cardiac arrest and resuscitation in which the inspired gas mixture was enriched with oxygen, resuscitability and survival were unaffected by positive pressure ventilation. In the present study, in a larger animal model, tidal volumes generated during precordial compression and with spont...

journal_title：Chest

authors： Noc M,Weil MH,Tang W,Turner T,Fukui M

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:FEV1 may remain stable while high-resolution CT (HRCT) appearances deteriorate in children with cystic fibrosis (CF). However, spirometry results commonly decline in older age groups. OBJECTIVES:To compare the rate of decline in HRCT abnormalities and spirometry results over time in an adult cohort with CF....

journal_title：Chest

authors： Judge EP,Dodd JD,Masterson JB,Gallagher CG

更新日期：2006-11-01 00:00:00

abstract：:The effect of clenbuterol, a beta adrenergic drug, and ambroxol, a secretolytic agent, on regional mucociliary clearance and pulmonary radioaerosol distribution was investigated in two groups of 15 patients with COLD in a double-blind cross-over trial with placebo. Clearance rates of inhaled 99mTc-labelled human serum...

journal_title：Chest

authors： Weiss T,Dorow P,Felix R

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVES:To review statistics on smoking prevalence and to analyze whether the implementation of national tobacco control legislation had an association with the prevalence of smoking, and thereby, with the occurrence of smoking-related lung diseases. DESIGN:Smoking prevalence rates (from 1960 to 2000), lung cancer ...

journal_title：Chest

authors： Heloma A,Nurminen M,Reijula K,Rantanen J

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Inadequate localized drug concentrations and systemic adverse effects are among the concerns when regional infections are treated with systemic antibiotics. We designed and fabricated a poly(D,L)-lactide-co-glycolide (PLGA)-based biodegradable drug delivery system and evaluated the release of antibiotics bot...

journal_title：Chest

authors： Liu KS,Liu SJ,Chen HY,Huang YK,Peng YJ,Wu RC,Ueng SW

更新日期：2012-05-01 00:00:00

abstract：:The literature on pulmonary function testing in sarcoidosis is critically reviewed. The results indicate that pulmonary function tests are not a reliable means for detecting the presence of parenchymal sarcoidosis, nor do they provide an accurate estimate of the extent of parenchymal disease. There are at present no k...

journal_title：Chest

authors： Winterbauer RH,Hutchinson JF

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Excessive sleepiness (ES) is a common symptom of OSA, which often persists despite primary OSA therapy. This phase III randomized withdrawal trial evaluated solriamfetol (JZP-110) for the treatment of ES in adults with OSA. METHODS:After 2 weeks of clinical titration (n = 174) and 2 weeks of stable dose adm...

journal_title：Chest

authors： Strollo PJ Jr,Hedner J,Collop N,Lorch DG Jr,Chen D,Carter LP,Lu Y,Lee L,Black J,Pépin JL,Redline S,Tones 4 Study Investigators.

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Long-acting bronchodilators, including long-acting beta2-agonists (LABA) and the anticholinergic tiotropium, are recommended as initial maintenance therapy in COPD. Studies to date have been limited in size and reported ambivalent results on the comparative risk of cardiovascular, cerebrovascular, and pulmon...

journal_title：Chest

authors： Suissa S,Dell'Aniello S,Ernst P

更新日期：2017-01-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the efficacy of albuterol by metered-dose inhaler (MDI) and spacer compared to a nebulizer. DESIGN:A prospective, open-label study. SETTING:Large urban emergency department (ED). PATIENTS:All consecutive adult asthma patients over a 2.5-year period. INTERVENTIONS:ED personnel used a st...

journal_title：Chest

authors： Newman KB,Milne S,Hamilton C,Hall K

更新日期：2002-04-01 00:00:00

abstract：:On the occasion of this Fourth World Conference on Lung Cancer, I am privileged to present the opening keynote address. This presentation has been sponsored by the Ontario Cancer Treatment and Research Foundation. In 1952, the Foundation established an annual lectureship in memory of one of their prominent physicians....

journal_title：Chest

authors： Pearson FG

更新日期：1986-04-01 00:00:00

abstract：:Between December 1985 and August 1988, there were 115 patients at 13 centers who were entered on a randomized comparison of tetracycline and bleomycin for treatment of malignant pleural effusions. Fifteen patients were not treated, primarily due to rapid progression of systemic cancer. Fifteen patients entered on a hi...

journal_title：Chest

authors： Ruckdeschel JC,Moores D,Lee JY,Einhorn LH,Mandelbaum I,Koeller J,Weiss GR,Losada M,Keller JH

更新日期：1991-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to assess the usefulness of a specific inspiratory muscle training in Duchenne muscular dystrophy (DMD). PATIENTS AND METHODS:Fifteen patients with DMD started 6 months of training the inspiratory muscles and 15 patients served as a control group. Pulmonary and inspiratory muscle func...

journal_title：Chest

authors： Wanke T,Toifl K,Merkle M,Formanek D,Lahrmann H,Zwick H

更新日期：1994-02-01 00:00:00

abstract：:The acute pulmonary responses of athletes after short-term exposure to ambient concentrations of NO2 during heavy exercise have been examined. Intercollegiate male athletes were screened for history of cardiac disease, respiratory disease, allergic conditions and extensive exposure to pollutants. After completion of s...

journal_title：Chest

authors： Kim SU,Koenig JQ,Pierson WE,Hanley QS

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Physicians are often asked about complementary therapies by patients with cancer, and data show that the interest in and use of these therapies among patients with cancer is common. Therefore, it is important to assess the current evidence base on the benefits and risks of complementary therapies (modalities...

journal_title：Chest

authors： Deng GE,Rausch SM,Jones LW,Gulati A,Kumar NB,Greenlee H,Pietanza MC,Cassileth BR

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Pulmonary vascular capacitance (PVC) is reduced in pulmonary arterial hypertension (PAH). In normal lung, PVC is largely a function of vascular compliance. In PAH, increased pulmonary vascular resistance (PVR) arises from the arterioles. PVR and PVC share pressure and volume variables. The dependency between...

journal_title：Chest

authors： Newman JH,Brittain EL,Robbins IM,Hemnes AR

更新日期：2015-04-01 00:00:00

abstract：:The relationship between changes in cardiac output and intrapulmonary shunt associated with mechanical ventilation was evaluated in 20 patients with the adult respiratory distress syndrome (ARDS). The distribution of ventilation-perfusion (VA/Q) ratios and the level of intrapulmonary shunt was determined by the multip...

journal_title：Chest

authors： Dantzker DR,Lynch JP,Weg JG

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:The relationships among systolic pulmonary artery pressure (SPAP), diastolic pulmonary artery pressure (DPAP), and mean pulmonary artery pressure (MPAP) have been found to be constant in humans breathing air, at rest, while supine. It would be important for those studying the pulmonary circulation if this re...

journal_title：Chest

authors： Syyed R,Reeves JT,Welsh D,Raeside D,Johnson MK,Peacock AJ

更新日期：2008-03-01 00:00:00

abstract：:Percutaneous cannulation of the internal jugular vein is commonly performed to obtain central venous access. We report the first case of massive hemoptysis occurring during cannulation of the internal jugular vein. ...

journal_title：Chest

authors： Friedman Y,Tilly E,Rackow EC,Weil MH

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a common complication of sarcoidosis that is associated with increased mortality. The pathogenesis of PH in sarcoidosis is uncertain, and the role of pulmonary arterial hypertension (PAH)-specific therapies remains to be determined. METHODS:We conducted a retrospective study o...

journal_title：Chest

authors： Barnett CF,Bonura EJ,Nathan SD,Ahmad S,Shlobin OA,Osei K,Zaiman AL,Hassoun PM,Moller DR,Barnett SD,Girgis RE

更新日期：2009-06-01 00:00:00

abstract：:These data suggest that the alveolar lining layer and lamellar body membranes contain the same saline-insoluble proteins, two of which are unusual in that they contain hydroxyproline and large amounts of glycine. Neither the function nor the origin of these glycopeptides has been established, and we are currently eval...

journal_title：Chest

authors： Passero MA,Bhattacharyya SN,Sahu S,Lynn WS

更新日期：1975-02-01 00:00:00

abstract：:We have assessed right and left ventricular function by multigated radionuclide ventriculography in 12 consecutive patients with acquired immunodeficiency syndrome (AIDS) grouped according to the CDC classification system for HIV infection. Results were correlated with clinical, electrocardiographic and echocardiograp...

journal_title：Chest

authors： Raffanti SP,Chiaramida AJ,Sen P,Wright P,Middleton JR,Chiaramida S

更新日期：1988-03-01 00:00:00

abstract：:We describe two patients with histologically proven pulmonary Langerhans' cell histiocytosis in whom radiologic improvement occurred following smoking cessation. The patients had 23- and 25-pack-year smoking histories, respectively. High-resolution CT revealed multiple small nodules, located predominantly in the upper...

journal_title：Chest

authors： Mogulkoc N,Veral A,Bishop PW,Bayindir U,Pickering CA,Egan JJ

更新日期：1999-05-01 00:00:00