A 75-Year-Old Man With Organizing Pneumonia Presenting With Worsening Dyspnea.

Abstract:

CASE PRESENTATION:A 75-year-old man was referred to our institution for worsening dyspnea, decreased activity tolerance, myalgias, and an increase in oxygen requirement. Nine months before the initial referral, the patient presented to an outside hospital for acute hypoxemic respiratory failure requiring a right-sided video-assisted thoracoscopic surgery (VATS) lung biopsy that disclosed organizing pneumonia (OP). He was treated with a prolonged steroid course starting at 1 mg/kg daily and tapered over 6 months to a baseline of 20 mg of prednisone daily and continuous oxygen (2 L/min). Prior attempts to further reduce prednisone resulted in worsening dyspnea, fevers, and myalgias. Despite optimal medical treatment for 3 months, he presented to our institution with progressive dyspnea, an increased oxygen requirement to 6 L/min, fatigue, and muscle weakness.

journal_name

Chest

journal_title

Chest

authors

Tseng S,Olson K,Shamsid-Deen N,Savajiyani S,Sista R,Hodges T,Saggar R

doi

10.1016/j.chest.2019.11.012

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

e161-e164

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(19)34290-4

journal_volume

157

pub_type

相关文献

CHEST文献大全
  • The induction of ventricular arrhythmias in acute myocardial ischemia by atrial pacing with long-short cycle sequences.

    abstract::Recent studies emphasize the importance of heart rate in the genesis of ventricular arrhythmias during myocardial ischemia. The role of alterations in rhythm has not previously been systematically investigated. In 20 dogs subjected to acute myocardial ischemia and crushing of the sinus node, standard electrocardiograp...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.71.5.651

    authors: Hope RR,Lazzara R,Scherlag BJ

    更新日期:1977-05-01 00:00:00

  • Optimizing coronary thrombolysis with i.v. administration of recombinant tissue plasminogen activator. Single bolus vs double bolus vs front-loading.

    abstract::This study was designed to compare the efficacy of coronary thrombolysis obtained with i.v. administration of three dose regimens of recombinant tissue plasminogen activator (rtPA). Although many studies have confirmed the efficacy of thrombolytic therapy in treatment of acute myocardial infarction, few prospective st...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.109.2.510

    authors: Prewitt RM,Schick U,Ducas J

    更新日期:1996-02-01 00:00:00

  • Prospective analysis of cystic fibrosis transmembrane regulator mutations in adults with bronchiectasis or pulmonary nontuberculous mycobacterial infection.

    abstract:BACKGROUND:Bronchiectasis and pulmonary infection with nontuberculous mycobacteria (NTM) may be associated with disease-causing mutations in the cystic fibrosis transmembrane regulator (CFTR). METHODS:Fifty adult patients at Stanford University Medical Center with a diagnosis of bronchiectasis and/or pulmonary NTM inf...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.4.995

    authors: Ziedalski TM,Kao PN,Henig NR,Jacobs SS,Ruoss SJ

    更新日期:2006-10-01 00:00:00

  • Intravegetation antimicrobial distribution in aortic endocarditis analyzed by computer-generated model. Implications for treatment.

    abstract::The distribution of antibiotics into cardiac valvular tissues is incompletely understood. By integrative computer modeling, we have used previously obtained pharmacokinetic data in experimental endocarditis to characterize aminoglycoside distribution within various geographic sectors of aortic vegetations of rabbits a...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.97.3.611

    authors: Bayer AS,Crowell D,Nast CC,Norman DC,Borrelli RL

    更新日期:1990-03-01 00:00:00

  • Effect of Balloon Pulmonary Angioplasty on Respiratory Function in Patients With Chronic Thromboembolic Pulmonary Hypertension.

    abstract:BACKGROUND:Balloon pulmonary angioplasty (BPA) in chronic thromboembolic pulmonary hypertension (CTEPH) improves hemodynamics and exercise capacity. However, its effect on respiratory function is unclear. Our objective was to investigate the effect of BPA on respiratory function. METHODS:We enrolled patients with inop...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2016.10.002

    authors: Akizuki M,Serizawa N,Ueno A,Adachi T,Hagiwara N

    更新日期:2017-03-01 00:00:00

  • Mucoid impaction of upper lobe bronchi in the absence of proximal bronchiectasis.

    abstract::Mucoid impaction is a complication of asthma and is frequently recurrent in patients with allergic bronchopulmonary aspergillosis (ABPA). This report describes a patient with asthma and recurrent bilateral well-circumscribed densities on chest roentgenogram in the absence of ABPA. Recognition of this clinical presenta...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.4.1023

    authors: Anderson WM

    更新日期:1990-10-01 00:00:00

  • Cardiorespiratory effects of pressure controlled ventilation in severe respiratory failure.

    abstract::Cardiorespiratory values were measured in ten patients with severe respiratory failure on volume controlled and pressure controlled ventilation. Tidal volume, respirator rate, PEEP, auto-PEEP, inspiratory:expiratory ratio (1:2) and FIo2 were maintained at the same value for both ventilatory modalities. Changing from V...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.98.6.1445

    authors: Abraham E,Yoshihara G

    更新日期:1990-12-01 00:00:00

  • Brief questionnaires for patient-reported outcomes in asthma: validation and usefulness in a primary care setting.

    abstract:UNLABELLED:STUDY OBJECTIVES AND DESIGN: Health-related quality of life (QoL) instruments are generally used for studies of asthma in specialized settings. For primary care use, there is a need for brief and simple questionnaires for structured patient-reported outcomes. We validated the Mini-Asthma Quality of Life Ques...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.129.4.925

    authors: Ehrs PO,Nokela M,Ställberg B,Hjemdahl P,Wikström Jonsson E

    更新日期:2006-04-01 00:00:00

  • Unilateral lymphocytic pleuritis as a manifestation of familial Mediterranean fever.

    abstract::Familial Mediterranean fever (FMF) is an autosomal recessive disease affecting predominantly populations surrounding the Mediterranean basin. It is the most prevalent hereditary periodic fever syndrome characterized mainly by recurrent and short attacks of fever and serositis (pleuritis, arthritis, peritonitis). Unila...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.07-1736

    authors: Katsenos S,Mermigkis C,Psathakis K,Tsintiris K,Polychronopoulos V,Panagou P,Ritis K,Light RW

    更新日期:2008-04-01 00:00:00

  • Feasibility of the detection of the sentinel lymph node in peripheral non-small cell lung cancer with radio isotopic and blue dye techniques.

    abstract:STUDY OBJECTIVES:The objective of this study was to evaluate the feasibility of the sentinel lymph node (SLN) biopsy in peripheral clinically stage I or II non-small cell lung cancer (NSCLC) using (99m)Tc colloid and a hand-held gamma detection probe, associated with a blue dye technique. DESIGN:Prospective study. SE...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.127.2.443

    authors: Tiffet O,Nicholson AG,Khaddage A,Prévot N,Ladas G,Dubois F,Goldstraw P

    更新日期:2005-02-01 00:00:00

  • Löffler's syndrome secondary to crack cocaine.

    abstract::Eosinophilic pulmonary infiltration is an uncommon presentation from cocaine abuse. We present a patient with migratory pulmonary infiltrates and eosinophilia consistent with Löffler's syndrome. Our review uncovered two other similar patients. The importance of early recognition is stressed in our report. Either absti...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.105.5.1599

    authors: Nadeem S,Nasir N,Israel RH

    更新日期:1994-05-01 00:00:00

  • Patient-focused care: using the right tools.

    abstract::Patient-focused or patient-centered care is not a new concept, but its value has been overlooked in preference to the technology-based, disease-centered model that has prevailed in medicine for the last 50 years. Patient-focused care includes four broad areas of intervention: communication with patients, partnerships,...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.130.1_suppl.73S

    authors: Irwin RS,Richardson ND

    更新日期:2006-07-01 00:00:00

  • Asystole and ventricular fibrillation associated with cocaine intoxication.

    abstract::We discuss a patient with cocaine intoxication in whom the initial presentation was that of asystole and ventricular fibrillation. Cocaine has a direct toxic action on the heart and also sensitizes cardiac tissue to the action of catecholamines. Cocaine intoxication should be considered in any patient with unexplained...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.85.1.132

    authors: Nanji AA,Filipenko JD

    更新日期:1984-01-01 00:00:00

  • Oxidant-antioxidant balance in granulocytes during ARDS. Effect of N-acetylcysteine.

    abstract::The production of cytotoxic oxygen radicals by activated granulocytes is a proposed mechanism of lung injury in ARDS. Protective effects of N-acetylcysteine (NAC) have been described in experimental and clinical ARDS. NAC could act in part by replenishing the intracellular stores of glutathione (GSH) in activated gran...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.109.1.163

    authors: Laurent T,Markert M,Feihl F,Schaller MD,Perret C

    更新日期:1996-01-01 00:00:00

  • Angiographic evidence of myocardial squeezing accompanying tachyarrhythmia as a possible cause of myocardial infarction.

    abstract::The coronary arteriogram of a 52-year-old man with Basedow's disease and who was suffering from myocardial infarction following rapid atrial fibrillation, showed severe myocardial squeezing without organic stenosis. Angiographically, the functional obstructive lesion was always observed both at systole and diastole du...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.73.3.431

    authors: Endo M,Lee YW,Hayashi H,Wada J

    更新日期:1978-03-01 00:00:00

  • Determinants of exhaled nitric oxide in chronic rhinosinusitis.

    abstract:BACKGROUND:Chronic rhinosinusitis (CRS) has been reported to be associated with increased values of exhaled nitric oxide (ENO), which could not be entirely explained by the association between CRS and asthma. The aim of this study was to investigate the variables associated with increased ENO in patients with CRS. MET...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.09-0667

    authors: Guida G,Rolla G,Badiu I,Marsico P,Pizzimenti S,Bommarito L,De Stefani A,Usai A,Bugiani M,Malinovschi A,Bucca C,Heffler E

    更新日期:2010-03-01 00:00:00

  • Epidemiology and outcomes of clostridium difficile-associated disease among patients on prolonged acute mechanical ventilation.

    abstract:PURPOSES:Patients receiving prolonged acute mechanical ventilation (PAMV), although comprising a third of all mechanical ventilation (MV) patients, consume two-thirds of all the resources allocated to MV, and their numbers are projected to double by 2020. By virtue of their prolonged hospital length of stay (median LOS...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.09-0596

    authors: Zilberberg MD,Nathanson BH,Sadigov S,Higgins TL,Kollef MH,Shorr AF

    更新日期:2009-09-01 00:00:00

  • Radiographic fibrosis score predicts survival in hypersensitivity pneumonitis.

    abstract:BACKGROUND:It is unknown if the radiographic fibrosis score predicts mortality in persistent hypersensitivity pneumonitis (HP) and if survival is similar to that observed in idiopathic pulmonary fibrosis (IPF) when adjusting for the extent of radiographic fibrosis. METHODS:We reviewed records from 177 patients with HP...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-2623

    authors: Mooney JJ,Elicker BM,Urbania TH,Agarwal MR,Ryerson CJ,Nguyen MLT,Woodruff PG,Jones KD,Collard HR,King TE Jr,Koth LL

    更新日期:2013-08-01 00:00:00

  • Minimal effect of alcohol ingestion on breathing during the sleep of postmenopausal women.

    abstract::Eighteen asymptomatic postmenopausal women volunteered to ingest 2 ml of 100-proof vodka per kg of body weight in orange juice on one night and a placebo on another. Overnight sleep monitoring was performed immediately thereafter. Alcohol ingestion caused reduction in total sleep time from 329 to 281 minutes and a dec...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.88.2.181

    authors: Block AJ,Hellard DW,Slayton PC

    更新日期:1985-08-01 00:00:00

  • Hematocrit levels in sleep apnea.

    abstract::This study addresses the hypothesis that patients with obstructive sleep apnea, who exhibit recurrent episodes of oxygen desaturation at night, have higher hematocrit levels than nonapneic control subjects. We prospectively studied 624 patients referred to the sleep disorders center at St. Michael's Hospital because o...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.3.787

    authors: Hoffstein V,Herridge M,Mateika S,Redline S,Strohl KP

    更新日期:1994-09-01 00:00:00

  • Massive pulmonary emboli in children: does fiber-optic-guided embolectomy have a role? Review of the literature and report of two cases.

    abstract::Massive pulmonary emboli is a rare disease in children, with only 39 reported cases in the last 50 years. Almost 50% of the patients died suddenly without receiving medical treatment. Most of the patients who were managed medically (70% of the treated patients) underwent surgical pulmonary embolectomy with 80% surviva...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.11-2759

    authors: Eini ZM,Houri S,Cohen I,Sion R,Tamir A,Sasson L,Mandelberg A

    更新日期:2013-02-01 00:00:00

  • Influence of maternal smoking on variability of peak expiratory flow rate in school children.

    abstract::Diurnal variability of peak expiratory flow rates (PEFRs) was assessed in 1,237 children. The PEFR was measured twice daily over a 1-week period. As an index of variability, the log of a week's mean of daily amplitude was calculated. Linear regression analyses revealed a significant positive association between matern...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.104.4.1133

    authors: Frischer T,Kühr J,Meinert R,Karmaus W,Urbanek R

    更新日期:1993-10-01 00:00:00

  • Endoscopic ultrasound/fine-needle aspiration diagnosis of a malignant subcarinal lymph node in a patient with lung cancer and a negative positron emission tomography scan.

    abstract::Transesophageal, endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) and positron emission tomography (PET) scanning are new modalities for staging non-small cell lung cancer (NSCLC), the roles of which are still being defined. A 78-year-old man with a right lower lobe (RLL) mass and mediastinal adenopathy...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.122.3.1091

    authors: Rosenberg JM,Perricone A,Savides TJ

    更新日期:2002-09-01 00:00:00

  • Gastroesophageal reflux disease and asthma: a longitudinal study in UK general practice.

    abstract:STUDY OBJECTIVES:Gastroesophageal reflux disease (GERD) and asthma are common causes for consultation in primary care, but the relationship between the two remains unclear. The aim of our study was to investigate the temporal relationship between first diagnoses of GERD and asthma in general practice. METHODS:We used ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.128.1.85

    authors: Ruigómez A,Rodríguez LA,Wallander MA,Johansson S,Thomas M,Price D

    更新日期:2005-07-01 00:00:00

  • Relationship of vancomycin minimum inhibitory concentration to mortality in patients with methicillin-resistant Staphylococcus aureus hospital-acquired, ventilator-associated, or health-care-associated pneumonia.

    abstract:BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and health-care-associated pneumonia (HCAP). These infections are associated with significant morbidity, mortality, and cost. The impact of vancomycin minimum inh...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.09-2453

    authors: Haque NZ,Zuniga LC,Peyrani P,Reyes K,Lamerato L,Moore CL,Patel S,Allen M,Peterson E,Wiemken T,Cano E,Mangino JE,Kett DH,Ramirez JA,Zervos MJ,Improving Medicine through Pathway Assessment of Critical Therapy of Hospital-Acqu

    更新日期:2010-12-01 00:00:00

  • A comprehensive, national survey of spirometry in Spain: current bottlenecks and future directions in primary and secondary care.

    abstract:BACKGROUND:We aimed to evaluate the availability and practice of spirometry, training of technicians, and spirometer features and maintenance in Spain in both primary care (PC) and secondary care (SC) centers. METHODS:We used a nationwide, cross-sectional, 36-item telephone survey of health-care centers in Spain to ta...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.12-2690

    authors: López-Campos JL,Soriano JB,Calle M,Encuesta de Espirometría en España (3E) Project.

    更新日期:2013-08-01 00:00:00

  • Urinary leukotriene E4 levels increase upon exposure to hypobaric hypoxia.

    abstract:STUDY OBJECTIVE:To determine whether urinary leukotriene E4 (uLTE4) levels increase upon exposure to high altitude, and also to ascertain the relationship between uLTE4 levels and symptoms of acute mountain sickness (AMS). DESIGN:Prospective, unblinded, single-factor (altitude) experimental study. SETTINGS:US Army re...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.110.4.946

    authors: Roach JM,Muza SR,Rock PB,Lyons TP,Lilly CM,Drazen JM,Cymerman A

    更新日期:1996-10-01 00:00:00

  • Diaphragm muscle thinning in patients who are mechanically ventilated.

    abstract:BACKGROUND:Approximately 40% of patients in medical ICUs require mechanical ventilation (MV). Approximately 20% to 25% of these patients will encounter difficulties in discontinuing MV. Multiple studies have suggested that MV has an unloading effect on the respiratory muscles that leads to diaphragmatic atrophy and dys...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.11-1638

    authors: Grosu HB,Lee YI,Lee J,Eden E,Eikermann M,Rose KM

    更新日期:2012-12-01 00:00:00

  • Occupational risk factors for sarcoidosis in African-American siblings.

    abstract:OBJECTIVES:To determine whether certain occupations and occupationally related exposures were associated with a history of sarcoidosis in African-American siblings. METHODS:We collected occupational data from 921 African Americans in 273 sibships that had been identified through a sarcoidosis case. Among the 648 sibli...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.123.5.1527

    authors: Kucera GP,Rybicki BA,Kirkey KL,Coon SW,Major ML,Maliarik MJ,Iannuzzi MC

    更新日期:2003-05-01 00:00:00

  • Implications of lower- and upper-limb training procedures in patients with chronic airway obstruction.

    abstract::In assessing the effectiveness of lower-limb and upper-limb nonspecific physical training, we have considered 3 objectives in this study: (1) determination of clinical and functional actual state in patients with chronic airway obstruction (CAO), before and after training; (2) determination of the tests, level of work...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.101.5_supplement.279s

    authors: Gimenez M,Predine E,Marchand M,Servera E,Ponz JL,Polu JM

    更新日期:1992-05-01 00:00:00