Urinary leukotriene E4 levels increase upon exposure to hypobaric hypoxia.

abstract：:We describe two patients who develop torsades de pointes in a temporal relationship to the intravenous administration of erythromycin lactobionate in the absence of other drugs or metabolic abnormalities known to cause the arrhythmia. We also review the current literature regarding this topic, including other case his...

journal_title：Chest

authors： Gitler B,Berger LS,Buffa SD

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Human telomere disease consists of a wide spectrum of disorders, including pulmonary, hepatic, and bone marrow abnormalities. The extent of bone marrow and liver abnormalities in patients with interstitial lung disease (ILD) and short telomeres is unknown. METHODS:The lung transplant clinic established a pr...

journal_title：Chest

authors： George G,Rosas IO,Cui Y,McKane C,Hunninghake GM,Camp PC,Raby BA,Goldberg HJ,El-Chemaly S

更新日期：2015-06-01 00:00:00

abstract：:The effects of one hour exposures of healthy nonsmoking human volunteers to submicrometer H2SO4 droplets via nasal mask on tracheobronchial mucociliary particle clearance were studied using two different sized monodisperse gamma-tagged Fe2O3 test aerosols. The larger sized Fe2O3 aerosol, 7.5 micrometers AMAD, was depo...

journal_title：Chest

authors： Lippmann M,Leikauf G,Spektor D,Schlesinger RB,Albert RE

更新日期：1981-12-01 00:00:00

abstract：:Open-chest direct cardiac compression represents a more potent but highly invasive option for cardiac resuscitation when conventional techniques of closed-chest cardiac resuscitation fail after prolonged cardiac arrest. We postulated that venoarterial extracorporeal circulation might be a more effective intervention w...

journal_title：Chest

authors： Gazmuri RJ,Weil MH,Terwilliger K,Shah DM,Duggal C,Tang W

更新日期：1992-12-01 00:00:00

abstract：STUDY OBJECTIVES:The etiologic role of bacterial pathogens isolated from sputum culture in 40 to 50% of acute exacerbations of chronic bronchitis (AECB) is controversial. If bacterial pathogens cause these AECB, they should be associated with greater neutrophilic airway inflammation than pathogen-negative exacerbations...

journal_title：Chest

authors： Sethi S,Muscarella K,Evans N,Klingman KL,Grant BJ,Murphy TF

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The study documented the emergence of new forms of resistant bacilli (totally drug-resistant [TDR] or super extensively drug-resistant [XDR] tuberculosis [TB] strains) among patients with multidrug-resistant TB (MDR-TB). METHODS:Susceptibility testing against first- and second-line drugs was performed on is...

journal_title：Chest

authors： Velayati AA,Masjedi MR,Farnia P,Tabarsi P,Ghanavi J,ZiaZarifi AH,Hoffner SE

更新日期：2009-08-01 00:00:00

abstract：STUDY OBJECTIVES:To determine and compare the values of positron emission tomography (PET) with F-18 fluorodeoxyglucose (FDG) and CT for predicting clinical outcome of patients with aggressive lymphoma undergoing salvage cytoreductive chemotherapy followed by high-dose chemotherapy and autologous stem-cell transplantat...

journal_title：Chest

authors： Filmont JE,Czernin J,Yap C,Silverman DH,Quon A,Phelps ME,Emmanouilides C

更新日期：2003-08-01 00:00:00

abstract：:Previously, we have reported in 1990 that 35% of carmustine treated patients (6 of 17) who survived childhood brain tumors died of pulmonary fibrosis between 2 and 13 years after treatment. In addition, 8 patients studied in 1989 (13 to 17 years post treatment), had physiologic and biopsy or radiologic evidence of pul...

journal_title：Chest

authors： O'Driscoll BR,Kalra S,Gattamaneni HR,Woodcock AA

更新日期：1995-05-01 00:00:00

abstract：:Aortic intramural hematoma (IMH) is related to but is pathologically distinct from aortic dissection. In this potentially lethal entity, there is hemorrhage into the aortic media in the absence of an intimal tear. Although intimal disruption is not present, the prognosis is similar to that of classic aortic dissection...

journal_title：Chest

authors： Sawhney NS,DeMaria AN,Blanchard DG

更新日期：2001-10-01 00:00:00

abstract：:Fifty-seven patients with rheumatoid arthritis (RA) were treated in hospital for diffuse interstitial lung fibrosis. Although interstitial fibrosis (either on the basis of lung function tests or chest roentgenograms or both) is fairly common among patients with RA, according to this study interstitial fibrosis of suff...

journal_title：Chest

authors： Hakala M

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Symptomatic malignant pleural effusions are common sequelae in patients with certain malignancies. Pleurodesis via bedside thoracostomy is the current treatment option most commonly used. To our knowledge, this is the first prospective randomized trial to examine which agent, bleomycin or talc slurry, is supe...

journal_title：Chest

authors： Zimmer PW,Hill M,Casey K,Harvey E,Low DE

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Critically ill patients who develop ARDS have substantial associated morbidity and mortality. Circulating mitochondrial DNA (mtDNA) released during critical illness causes endothelial dysfunction and lung injury in experimental models. This study hypothesized that elevated plasma mtDNA is associated with ARD...

journal_title：Chest

authors： Faust HE,Reilly JP,Anderson BJ,Ittner CAG,Forker CM,Zhang P,Weaver BA,Holena DN,Lanken PN,Christie JD,Meyer NJ,Mangalmurti NS,Shashaty MGS

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:When evaluating peripheral pulmonary lesions, a 3.0-mm ultrathin bronchoscope (UTB) with a 1.7-mm working channel is advantageous regarding good access to the peripheral airway, whereas a 4.0-mm thin bronchoscope provides a larger 2.0-mm working channel, which allows the use of various instruments including ...

journal_title：Chest

authors： Oki M,Saka H,Asano F,Kitagawa C,Kogure Y,Tsuzuku A,Ando M

更新日期：2019-11-01 00:00:00

abstract：:The efficacy of a nasopharyngeal tube was evaluated in 44 patients with obstructive sleep apnea syndrome. Twenty-four of these patients underwent repeated polysomnographic studies with the nasopharyngeal tube in place. They had a 62.3 percent decrease in apnea index and a 39.2 percent decrease in disordered breathing ...

journal_title：Chest

authors： Nahmias JS,Karetzky MS

更新日期：1988-12-01 00:00:00

abstract：:A unique association of giant lymph node hyperplasia (Castleman's disease) and cardiac tamponade is presented. Although pleural effusions have been previously described with Castleman's disease, the authors believe this to be the first report of pericardial effusion and tamponade with this entity. The development of e...

journal_title：Chest

authors： Nicolosi AC,Almassi GH,Komorowski R

更新日期：1994-02-01 00:00:00

abstract：STUDY OBJECTIVES:To determine whether an association exists between aortic calcification viewed on plain chest radiography and coronary artery disease. METHODS:Retrospective review of all chest radiographs obtained from consecutive patients undergoing coronary angiography at a primary cardiac center during 1999. Plain...

journal_title：Chest

authors： Li J,Galvin HK,Johnson SC,Langston CS,Sclamberg J,Preston CA

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) and histamine type 2 receptor blockers (H2Bs) are used for stress ulcer prophylaxis. Although the PPIs have greater potency for acid suppression, their relative effectiveness for preventing clinically important GI bleeding (CIGIB) has not been established. The goal of this study...

journal_title：Chest

authors： Lilly CM,Aljawadi M,Badawi O,Onukwugha E,Tom SE,Magder LS,Harris I

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:A comprehensive evaluation of temporal trends in the treatment of patients who have DVT may assist with identification of modifiable factors that contribute to short-term outcomes. METHODS:We assessed temporal trends in length of hospital stay and use of pharmacological and interventional therapies among 26...

journal_title：Chest

authors： Morillo R,Jiménez D,Aibar MÁ,Mastroiacovo D,Wells PS,Sampériz Á,Saraiva de Sousa M,Muriel A,Yusen RD,Monreal M,RIETE investigators.

更新日期：2016-08-01 00:00:00

abstract：UNLABELLED:Formoterol solution aerosol has proved to be a fast and long-acting beta 2-sympathicomimetic drug in many clinical trials. The physical stability, however, was such that storage needed to be at 4 degrees C to 8 degrees C before first use; afterwards, the aerosol could be used for another three months at room...

journal_title：Chest

authors： Maesen FP,Nakratzas G,Bantje TA,Prins J,Zweers PG

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Although the physiologic range of pulmonary artery systolic pressure (PASP) has been reported, data on how it is manifested in athletes are limited. The aim of the present study was to explore the full spectrum of PASP and the long-term training impact in a large population of highly trained athletes. METHO...

journal_title：Chest

authors： D'Andrea A,Naeije R,D'Alto M,Argiento P,Golia E,Cocchia R,Riegler L,Scarafile R,Limongelli G,Di Salvo G,Citro R,Caso P,Russo MG,Calabrò R,Bossone E

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a frequent cause of morbidity and mortality in patients with systemic sclerosis (SSc). PAH is generally considered to be a late complication of limited cutaneous SSc. This study identified and investigated a subset of SSc patients with early-onset PAH. METHODS:Clinic...

journal_title：Chest

authors： Hachulla E,Launay D,Mouthon L,Sitbon O,Berezne A,Guillevin L,Hatron PY,Simonneau G,Clerson P,Humbert M,French PAH-SSc Network.

更新日期：2009-11-01 00:00:00

abstract：:In the past decade and a half, the introduction of new therapeutic agents has revolutionized the management of pulmonary arterial hypertension (PAH). These new treatment options have improved the quality of life and survival in PAH. With an armamentarium of options available, the identification of unique phenotypes ca...

journal_title：Chest

authors： Medrek SK,Sahay S

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The leading cause of pericardial effusion in urban hospitals is now AIDS-related pathologies. Clinically, these effusions are a diagnostic and management dilemma. In our institution, pericardial biopsy and operative drainage have become part of the diagnostic and management plan. Surgical intervention, howev...

journal_title：Chest

authors： Flum DR,McGinn JT Jr,Tyras DH

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Unlike studies on leg exercise, reports on the regulation of dynamic hyperinflation during arm exercise are scanty. We ascertained the following in patients with COPD: (1) whether and to what extent upper-limb exercise results in dynamic hyperinflation, and (2) the mechanism whereby an arm-training program (...

journal_title：Chest

authors： Gigliotti F,Coli C,Bianchi R,Grazzini M,Stendardi L,Castellani C,Scano G

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The long-term clinical course of asthma in patients with eosinophilic granulomatosis with polyangiitis (EGPA) remains unclear. We aimed to characterize long-term asthma in EGPA and to identify baseline predictors of long-term asthma severity. METHODS:This retrospective cohort study included patients who ful...

journal_title：Chest

authors： Berti A,Cornec D,Casal Moura M,Smyth RJ,Dagna L,Specks U,Keogh KA

更新日期：2020-05-01 00:00:00

abstract：:A 72-year-old physician with myeloid metaplasia developed marked thrombocytosis, pulmonary hypertension, and right heart failure following splenectomy. No cause for the pulmonary hypertension could be found. The pulmonary hypertension and right heart failure returned to normal when hydroxyurea therapy corrected the th...

journal_title：Chest

authors： Marvin KS,Spellberg RD

更新日期：1993-02-01 00:00:00

abstract：STUDY OBJECTIVES:The aim of this study was to evaluate the immediate and midterm results of coronary artery bypass grafting with the radial artery (RA) as a conduit. PATIENTS:Two hundred forty-one patients underwent myocardial revascularization using the RA. In 78.5% of patients, three coronary vessels were involved, ...

journal_title：Chest

authors： Beghi C,Nicolini F,Budillon AM,Borrello B,Ballore L,Reverberi C,Gherli T

更新日期：2002-12-01 00:00:00

abstract：STUDY OBJECTIVE:Laboratory testing plays a minor role in the assessment of aortic dissection. Its main value is in the exclusion of other diseases. Following an incidental observation, we systematically investigated the relationship between elevated d-dimer levels and acute aortic dissection. DESIGN:We prospectively t...

journal_title：Chest

authors： Weber T,Högler S,Auer J,Berent R,Lassnig E,Kvas E,Eber B

更新日期：2003-05-01 00:00:00

abstract：:Lung volume reduction surgery (LVRS) is being evaluated in the treatment of emphysema. The proposed mechanisms of improvement are increased elastic recoil of the lung and improved mechanical efficiency of the muscles of respiration. We report a unique patient with emphysema who developed a giant bulla 3 years subseque...

journal_title：Chest

authors： Iqbal M,Rossoff L,McKeon K,Graver M,Scharf SM

更新日期：1999-12-01 00:00:00

abstract：STUDY OBJECTIVES:To describe the health-related quality of life (HRQL) and mental health of persons with sarcoidosis, as well as to assess physician-patient agreement about the presence of sarcoidosis symptoms. DESIGN AND SETTING:Cross-sectional study at three university medical center outpatient pulmonary clinics. P...

journal_title：Chest

authors： Cox CE,Donohue JF,Brown CD,Kataria YP,Judson MA

更新日期：2004-03-01 00:00:00