Torsades de pointes induced by erythromycin.

Abstract:

:We describe two patients who develop torsades de pointes in a temporal relationship to the intravenous administration of erythromycin lactobionate in the absence of other drugs or metabolic abnormalities known to cause the arrhythmia. We also review the current literature regarding this topic, including other case histories and the evidence for erythromycin's effect on cardiac tissue. Due to the increasing use of erythromycin in clinical practice, we believe it is important that all physicians be made aware of this potential complication, which was not recognized at our institutions until these patients were seen by one of us (B.G.).

journal_name

Chest

journal_title

Chest

authors

Gitler B,Berger LS,Buffa SD

doi

10.1378/chest.105.2.368

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

368-72

issue

2

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)47369-1

journal_volume

105

pub_type

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