Unilateral lymphocytic pleuritis as a manifestation of familial Mediterranean fever.

Abstract:

:Familial Mediterranean fever (FMF) is an autosomal recessive disease affecting predominantly populations surrounding the Mediterranean basin. It is the most prevalent hereditary periodic fever syndrome characterized mainly by recurrent and short attacks of fever and serositis (pleuritis, arthritis, peritonitis). Unilateral polymorphonuclear exudative pleuritis associated with fever has been reported as the solitary manifestation of the first FMF attack, in < 10% of patients. This case study describes a 30-year-old Greek man with recurrent episodes of lymphocytic exudative pleuritis associated with fever. After a thorough workup (clinical criteria and molecular genetic testing identifying homozygosity polymorphisms of the FMF gene), the diagnosis of FMF was established. Treatment with colchicine, 2 mg/d, eliminated FMF attacks. To our knowledge, this is the first well-documented case report of a patient with FMF presenting with a lymphocytic exudative pleural effusion.

journal_name

Chest

journal_title

Chest

authors

Katsenos S,Mermigkis C,Psathakis K,Tsintiris K,Polychronopoulos V,Panagou P,Ritis K,Light RW

doi

10.1378/chest.07-1736

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

999-1001

issue

4

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)49691-6

journal_volume

133

pub_type

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