Abstract:
:Familial Mediterranean fever (FMF) is an autosomal recessive disease affecting predominantly populations surrounding the Mediterranean basin. It is the most prevalent hereditary periodic fever syndrome characterized mainly by recurrent and short attacks of fever and serositis (pleuritis, arthritis, peritonitis). Unilateral polymorphonuclear exudative pleuritis associated with fever has been reported as the solitary manifestation of the first FMF attack, in < 10% of patients. This case study describes a 30-year-old Greek man with recurrent episodes of lymphocytic exudative pleuritis associated with fever. After a thorough workup (clinical criteria and molecular genetic testing identifying homozygosity polymorphisms of the FMF gene), the diagnosis of FMF was established. Treatment with colchicine, 2 mg/d, eliminated FMF attacks. To our knowledge, this is the first well-documented case report of a patient with FMF presenting with a lymphocytic exudative pleural effusion.
journal_name
Chestjournal_title
Chestauthors
Katsenos S,Mermigkis C,Psathakis K,Tsintiris K,Polychronopoulos V,Panagou P,Ritis K,Light RWdoi
10.1378/chest.07-1736subject
Has Abstractpub_date
2008-04-01 00:00:00pages
999-1001issue
4eissn
0012-3692issn
1931-3543pii
S0012-3692(15)49691-6journal_volume
133pub_type
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