Prostacyclin but not phentolamine increases oxygen consumption and skin microvascular blood flow in patients with sepsis and respiratory failure.

abstract：AIMS:This study investigated whether right ventricular (RV) diastolic function is impaired in pulmonary hypertension (PH) patients, and whether it is related to RV mass and afterload. In addition, the effects of an acute reduction of RV afterload by the oral intake of sildenafil were studied. Finally, we assessed wheth...

journal_title：Chest

authors： Gan CT,Holverda S,Marcus JT,Paulus WJ,Marques KM,Bronzwaer JG,Twisk JW,Boonstra A,Postmus PE,Vonk-Noordegraaf A

更新日期：2007-07-01 00:00:00

abstract：:The aim of this prospective study was to determine the rate of recurrence for spontaneous pneumothorax (SP) after tetracycline pleurodesis (TCP), using that of observation, tube thoracostomy alone, and thoracotomy as references. From 1985 to the end of 1991, 78 patients were treated with tetracycline pleurodesis and 1...

journal_title：Chest

authors： Alfageme I,Moreno L,Huertas C,Vargas A,Hernandez J,Beiztegui A

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Although the physiologic range of pulmonary artery systolic pressure (PASP) has been reported, data on how it is manifested in athletes are limited. The aim of the present study was to explore the full spectrum of PASP and the long-term training impact in a large population of highly trained athletes. METHO...

journal_title：Chest

authors： D'Andrea A,Naeije R,D'Alto M,Argiento P,Golia E,Cocchia R,Riegler L,Scarafile R,Limongelli G,Di Salvo G,Citro R,Caso P,Russo MG,Calabrò R,Bossone E

更新日期：2011-04-01 00:00:00

abstract：:Portopulmonary hypertension (PPHTN) is an uncommon complication of advanced liver disease. Epoprostenol has been effective in the treatment of PPHTN and has been used as a bridge to orthotopic liver transplantation (OLT). The role of OLT in the reversal of PPHTN is unclear. We report a case of severe PPHTN (mean pulmo...

journal_title：Chest

authors： Rafanan AL,Maurer J,Mehta AC,Schilz R

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension, which is related to right ventricular (RV) failure, indicates a poor prognosis in heart failure (HF). Increased ventilatory response and exercise oscillatory ventilation (EOV) also have a negative impact. We hypothesized that the severity classification of HF and risk prediction could...

journal_title：Chest

authors： Guazzi M,Naeije R,Arena R,Corrà U,Ghio S,Forfia P,Rossi A,Cahalin LP,Bandera F,Temporelli P

更新日期：2015-07-01 00:00:00

abstract：:Two patients were treated for AIDS-associated bilateral pneumothoraces which persisted despite prolonged chest tube drainage. Heimlich flutter valves were used to facilitate the outpatient management of these patients. ...

journal_title：Chest

authors： Driver AG,Peden JG,Adams HG,Rumley RL

更新日期：1991-07-01 00:00:00

abstract：:Uhl's disease is a rare disorder originally described in 1952 in an infant with severe diffuse right ventricular dysfunction with total absence of the myocardium. Uhl considered the disease to be congenital in origin. We report a patient with severe dilated congestive cardiomyopathy limited to the right ventricle but ...

journal_title：Chest

authors： Bewick DJ,Chandler BM,Montague TJ

更新日期：1986-08-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the clinical and radiographic findings of nontuberculous mycobacteria (NTM) other than Mycobacterium avium complex (MAC) and Mycobacterium kansasii in AIDS compared with non-AIDS patients. DESIGN:A retrospective chart review of all patients in whom NTM other than MAC complex and M kansasii...

journal_title：Chest

authors： El-Solh AA,Nopper J,Abdul-Khoudoud MR,Sherif SM,Aquilina AT,Grant BJ

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:alpha(1)-Antitrypsin (AAT)-Z deficiency is a risk factor for the development of COPD. Compared to wild-type M, AAT-Z has an increased tendency to polymerize, rendering it inactive as a serine proteinase inhibitor. It has been demonstrated that wild-type M- and Z-deficiency AAT polymers are chemotactic for hu...

journal_title：Chest

authors： Persson C,Subramaniyam D,Stevens T,Janciauskiene S

更新日期：2006-06-01 00:00:00

abstract：:Clonidine was given to patients with essential hypertension, renovascular hypertension, and hypertension with parenchymal renal disease. The drug was effective in all groups but was more effective in patients with high plasma renin concentration. Renal function did not deteriorate when the drug was used, and there was...

journal_title：Chest

authors： Morgan T

更新日期：1983-02-01 00:00:00

abstract：:Endobronchial ultrasonography (EBUS) has become an invaluable tool in the diagnosis of patients with a variety of thoracic abnormalities. The majority of EBUS procedures are used to diagnose and stage mediastinal and hilar abnormalities, as well as peripheral pulmonary targets, with a probe-based technology. Nearly 1,...

journal_title：Chest

authors： Gildea TR,Nicolacakis K

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial infarction, and stroke. METHODS:The methods of this guideline f...

journal_title：Chest

authors： Linkins LA,Dans AL,Moores LK,Bona R,Davidson BL,Schulman S,Crowther M

更新日期：2012-02-01 00:00:00

abstract：:Widespread use of thrombolytic agents in a variety of settings has highlighted the need for measures of safety and efficacy. Previously used laboratory parameters, such as decreasing levels of fibrinogen and increasing levels of fibrin(ogen) degradation products (FDPs), have failed to correlate consistently with hemor...

journal_title：Chest

authors： Hirsch DR,Goldhaber SZ

更新日期：1990-04-01 00:00:00

abstract：:Data on pulmonary function, with particular reference to flow-volumes, were obtained in 760 normal healthy Indians in Bombay, who had never smoked and who had no symptom or history of cardiorespiratory disease. Prediction equations were derived for spirometric parameters and for maximal expiratory flows. The maximal e...

journal_title：Chest

authors： Udwadia FE,Sunavala JD,Shetye VM,Jain PK

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Successful management of chronic cough has varied in the primary research studies in the reported literature. One of the potential reasons relates to a lack of intervention fidelity to the core elements of the diagnostic and/or therapeutic interventions that were meant to be used by the investigators. METHO...

journal_title：Chest

authors： French CT,Diekemper RL,Irwin RS,Adams TM,Altman KW,Barker AF,Birring SS,Blackhall F,Bolser DC,Boulet LP,Braman SS,Brightling C,Callahan-Lyon P,Canning BJ,Chang AB,Coeytaux R,Cowley T,Davenport P,Diekemper RL,Ebihara

更新日期：2015-07-01 00:00:00

abstract：:The ST alternans was recorded during at least one ischemic attack with ST elevation in nine of 65 patients with variant angina. The magnitude and duration of ST elevation during ischemic attacks were significantly greater in patients with than in those without ST alternans. It always appeared during the occlusion phas...

journal_title：Chest

authors： Turitto G,El-Sherif N

更新日期：1988-03-01 00:00:00

abstract：STUDY OBJECTIVES:To assess the incidence of tuberculosis in the native and immigrant populations of southern Israel in the period between 1992 and 1997, and to study the prevalence of drug resistance overall and among these subpopulations in the region in order to create guidelines for empirical antituberculous treatme...

journal_title：Chest

authors： Gilad J,Borer A,Riesenberg K,Peled N,Schlaeffer F

更新日期：2000-03-01 00:00:00

abstract：:If we hope to repair damaged lung tissue associated with a variety of acquired and developmental diseases, we must first gain a full appreciation of normal lung development. As an approach, we have utilized Affymetrix (Santa Clara, CA) high-density, oligonucleotide-based microarrays to generate an expression profile o...

journal_title：Chest

authors： Mariani TJ,Shapiro SD

更新日期：2002-03-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the utility of urinary uric acid excretion as a marker of nocturnal hypoxia in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) before and after the institution of nasal continuous positive airway pressure (CPAP). DESIGN:Prospective, open. SETTING:Sleep Disorders Laboratory, V...

journal_title：Chest

authors： Sahebjani H

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) is considered a useful and minimally invasive modality for treating centrally located early lung cancer. To date, there has been limited information on the long-term outcome of patients treated with PDT, especially those who are medically operable. METHODS:Beginning in 1994, patie...

journal_title：Chest

authors： Endo C,Miyamoto A,Sakurada A,Aikawa H,Sagawa M,Sato M,Saito Y,Kondo T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and health-care-associated pneumonia (HCAP). These infections are associated with significant morbidity, mortality, and cost. The impact of vancomycin minimum inh...

journal_title：Chest

authors： Haque NZ,Zuniga LC,Peyrani P,Reyes K,Lamerato L,Moore CL,Patel S,Allen M,Peterson E,Wiemken T,Cano E,Mangino JE,Kett DH,Ramirez JA,Zervos MJ,Improving Medicine through Pathway Assessment of Critical Therapy of Hospital-Acqu

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:CD14 is a cell surface glycoprotein expressed mainly on mature monocytes and macrophages. Soluble CD14 (sCD14) is present in normal plasma and is found increased in serum of patients with septicemia, polytrauma, and sarcoidosis. In active sarcoidosis, increased levels of sCD14 in BAL supernatant have been ...

journal_title：Chest

authors： Hoheisel G,Zheng L,Teschler H,Striz I,Costabel U

更新日期：1995-12-01 00:00:00

abstract：STUDY OBJECTIVES:To determine if persistent airway tissue mast cells are associated with treatment failure when patients discontinue inhaled corticosteroids (ICS). DESIGN:Double-blind, randomized, placebo-controlled trial. SETTING:Multicenter, tertiary referral centers. PATIENTS OR PARTICIPANTS:Forty-five subjects w...

journal_title：Chest

authors： Kraft M,Martin RJ,Lazarus SC,Fahy JV,Boushey HA,Lemanske RF Jr,Szefler SJ,Asthma Clinical Research Network.

更新日期：2003-07-01 00:00:00

abstract：:Expired gas and gas leaked via thoracostomy tubes was collected in nine patients with the adult respiratory distress syndrome (ARDS) and bronchopleural fistulas. Mean minute ventilation in the group was 23.9 +/- 7.5 L/min with 31 +/- 23 percent of the gas escaping via the leak. Carbon dioxide was present in the leaked...

journal_title：Chest

authors： Bishop MJ,Benson MS,Pierson DJ

更新日期：1987-03-01 00:00:00

abstract：:Bronchial epithelial damage and mucus hypersecretion are characteristic features of chronic airway inflammation that can impair mucociliary clearance and can cause recurrent or persistent respiratory infection. In response to chemoattractants produced by damaged or inflamed tissue, neutrophils move through sequential ...

journal_title：Chest

authors： Tamaoki J

更新日期：2004-02-01 00:00:00

abstract：:We wished to identify the physiologic abnormalities that distinguish severely breathless (SB) patients with chronic airflow limitation (CAL) from mildly breathless (MB) patients. Thirty-seven patients with stable, advanced CAL (FEV1 = 38 +/- 10 percent predicted, mean +/- SD) were separated into two distinct groups, S...

journal_title：Chest

authors： O'Donnell DE,Webb KA

更新日期：1992-09-01 00:00:00

abstract：:Preclinical studies indicate that allogeneic human mesenchymal stem cells (MSC) may be useful for the treatment of several clinical disorders, including sepsis, acute renal failure, acute myocardial infarction, and more recently, acute lung injury (ALI). This article provides a brief review of the biologic qualities o...

journal_title：Chest

authors： Matthay MA,Thompson BT,Read EJ,McKenna DH Jr,Liu KD,Calfee CS,Lee JW

更新日期：2010-10-01 00:00:00

abstract：:Massive pulmonary emboli is a rare disease in children, with only 39 reported cases in the last 50 years. Almost 50% of the patients died suddenly without receiving medical treatment. Most of the patients who were managed medically (70% of the treated patients) underwent surgical pulmonary embolectomy with 80% surviva...

journal_title：Chest

authors： Eini ZM,Houri S,Cohen I,Sion R,Tamir A,Sasson L,Mandelberg A

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:FEV1 may remain stable while high-resolution CT (HRCT) appearances deteriorate in children with cystic fibrosis (CF). However, spirometry results commonly decline in older age groups. OBJECTIVES:To compare the rate of decline in HRCT abnormalities and spirometry results over time in an adult cohort with CF....

journal_title：Chest

authors： Judge EP,Dodd JD,Masterson JB,Gallagher CG

更新日期：2006-11-01 00:00:00

abstract：STUDY OBJECTIVE:To reevaluate whether it is possible to reliably differentiate malignant mediastinal lymph nodes from benign nodes by size, and to determine the frequency of metastases to normal-sized mediastinal lymph nodes that directly affects the sensitivity for detecting malignant mediastinal lymph nodes (N2 nodes...

journal_title：Chest

authors： Arita T,Matsumoto T,Kuramitsu T,Kawamura M,Matsunaga N,Sugi K,Esato K

更新日期：1996-10-01 00:00:00