Living cytology: A new diagnostic technique for malignant pleural effusions.

Abstract:

:The efficacy of a new tissue-culture technique for the diagnosis of malignant pleural effusions was contrasted with conventional cytologic methods. The new technique is based on the ability of the tissue-culture medium to transform mesothelial cells into fibroblasts while not sustaining lymphoreticular cells. Against a background of fibroblasts, islets of adenocarcinoma are easily identified. Of 20 patients with pleural effusions and solid tumors, the tissue-culture technique correctly diagnosed eight (40 percent), compated to seven (35 percent) for conventional cytologic methods. Of 27 pleural effusions in patients without malignant neoplasms, there was only one probable false-positive.

journal_name

Chest

journal_title

Chest

authors

Monif GR,Stewart BN,Block AJ

doi

10.1378/chest.69.5.626

subject

Has Abstract

pub_date

1976-05-01 00:00:00

pages

626-9

issue

5

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)38259-9

journal_volume

69

pub_type

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