Ventilatory effects of doxapram in conscious human subjects.

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with 3 to 5 years' survival. Although FVC is used to assess disease progression and treatment response, identifying predictive circulating blood biomarkers could help identify specific biologic pathways for treatment. An international, prospective, ...

journal_title：Chest

authors： Raghu G,Richeldi L,Jagerschmidt A,Martin V,Subramaniam A,Ozoux ML,Esperet CA,Soubrane C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To highlight the incidence of subglottic stenosis (SGS) as a complication of surgery for congenital heart disease and the role of single-stage laryngotracheoplasty in treating this complication. DESIGN:Retrospective case series. SETTING:University-based referral center specializing in surgery for congenital...

journal_title：Chest

authors： Pereira KD,Mitchell RB,Younis RT,Lazar RH

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Inhaled magnesium (Mg) seemed to have a mild protective (nonbronchodilator) effect against histamine and methacholine. Inhaled sodium metabisulfite (MBS) causes bronchoconstriction in asthma through indirect mechanisms that involve sensory nerve stimulation, and it is extensively used to study airway hyperre...

journal_title：Chest

authors： Nannini LJ Jr,Hofer D

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Clinical resolution of ventilator-associated pneumonia (VAP) determines the duration of treatment and mechanical ventilation. The aim of this study was to evaluate the influence of organisms and their susceptibility to treatment on outcomes. METHODS:Prospective observational study in three teaching ICUs. Si...

journal_title：Chest

authors： Vidaur L,Planas K,Sierra R,Dimopoulos G,Ramirez A,Lisboa T,Rello J

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The World Trade Center (WTC) collapse on September 11, 2001, produced airflow obstruction in a majority of firefighters receiving subspecialty pulmonary evaluation (SPE) within 6.5 years post-September 11, 2001. METHODS:In a cohort of 801 never smokers with normal pre-September 11, 2001, FEV1, we correlated...

journal_title：Chest

authors： Nolan A,Naveed B,Comfort AL,Ferrier N,Hall CB,Kwon S,Kasturiarachchi KJ,Cohen HW,Zeig-Owens R,Glaser MS,Webber MP,Aldrich TK,Rom WN,Kelly K,Prezant DJ,Weiden MD

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Eosinophils contain granule proteins such as eosinophil cationic protein (ECP) that have proinflammatory effects on airways. ECP may be released on activation of eosinophils into the plasma and is widely used as a marker of bronchial hyperreactivity and allergic inflammation. Environmental factors as well as...

journal_title：Chest

authors： Domej W,Schwaberger G,Tilz GP,Földes-Papp Z,Demel U,Lang J,von Duvillard SP

更新日期：2002-04-01 00:00:00

abstract：STUDY OBJECTIVE:To investigate the role of oropharyngeal and cutaneous commensal microorganisms (OCCs) as a cause of ventilator-associated pneumonia (VAP). DESIGN:Retrospective analysis of the medical and microbiological records. SETTING:One medical-surgical ICU. PATIENTS:All VAP episodes recorded during a 10-year p...

journal_title：Chest

authors： Lambotte O,Timsit JF,Garrouste-Orgeas M,Misset B,Benali A,Carlet J

更新日期：2002-10-01 00:00:00

abstract：:Pulmonary hypertension in chronic obstructive pulmonary disease (COPD) is associated with a poor prognosis. Reduction of pulmonary artery pressure in COPD by prolonged oxygen treatment has been shown to be associated with increased survival. In an attempt to find a suitable pharmacologic method of reducing pulmonary a...

journal_title：Chest

authors： Sajkov D,McEvoy RD,Cowie RJ,Bradley JA,Antic R,Morris RG,Frith PA

更新日期：1993-05-01 00:00:00

abstract：:Fifteen patients in the early stages of the adult respiratory distress syndrome with severe hypoxemia who were capable of maintaining adequate spontaneous ventilation were treated with continuous positive airway pressure (CPAP). The optimal level of CPAP was adjusted for each patient to achieve the highest oxygenation...

journal_title：Chest

authors： Venus B,Jacobs HK,Lim L

更新日期：1979-09-01 00:00:00

abstract：:Nearly all patients with pulmonary embolism (PE) have complete clinical and hemodynamic and at least near complete roentgenographic and angiographic resolution within four to six weeks of the acute event. To classify the syndrome of unresolved pulmonary embolism we reviewed our experience and that of the English liter...

journal_title：Chest

authors： Benotti JR,Ockene IS,Alpert JS,Dalen JE

更新日期：1983-12-01 00:00:00

abstract：:Fluid infusion may be lifesaving in patients with severe sepsis, especially in the earliest phases of treatment. Following initial resuscitation, however, fluid boluses often fail to augment perfusion and may be harmful. In this review, we seek to compare and contrast the impact of fluids in early and later sepsis; sh...

journal_title：Chest

authors： Durairaj L,Schmidt GA

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Little is known about factors determining the pathogenesis and severity of asthma in Latin American countries. Costa Rica, one of the most prosperous Latin American nations, has a very high asthma prevalence. OBJECTIVE:To examine the relation between potential risk factors and childhood asthma in Costa Rica...

journal_title：Chest

authors： Celedón JC,Soto-Quiros ME,Silverman EK,Hanson L,Weiss ST

更新日期：2001-09-01 00:00:00

abstract：:The role of thoracic radiation therapy in the management of limited-stage small cell lung cancer (SCLC) is reviewed. Although chest irradiation has been used to treat SCLC for over four decades, its standard role in the management of limited-stage disease was established only during the last decade. Multiple prospecti...

journal_title：Chest

authors： Kumar P

更新日期：1997-10-01 00:00:00

abstract：:Two patients with the adult respiratory distress syndrome (ARDS) were placed on pressure-controlled inverse-ratio ventilation (IRV) when their condition deteriorated despite optimal treatment with intermittent mandatory ventilation and positive end-expiratory pressure. In the first case, high peak airway pressure was ...

journal_title：Chest

authors： Gurevitch MJ,Van Dyke J,Young ES,Jackson K

更新日期：1986-02-01 00:00:00

abstract：:The effects of erythromycin on the NADPH oxidase activity in the neutrophils of normal subjects and patients with bronchiolitis were investigated. In the patients receiving erythromycin, NADPH oxidase activity was significantly lower in a whole-cell system than that before therapy. Erythromycin was also found to inhib...

journal_title：Chest

authors： Umeki S

更新日期：1993-10-01 00:00:00

abstract：:Persisting symptoms, consisting of palpitations, dizziness, or syncope, were found in 49 of 570 consecutively followed patients (8.6 percent) with permanent pacemakers (PM). Among 540 patients with ventricular PM, 19 had syncope and 24 dizziness; among 30 patients with dual-chamber PM, five had palpitations and one di...

journal_title：Chest

authors： Hoffman A,Jost M,Pfisterer M,Burkart F,Burckhardt D

更新日期：1984-02-01 00:00:00

abstract：:Transient left ventricular (LV) dysfunction syndrome, or Tako-tsubo syndrome, occurs following intense emotional or physical stress and simulates the clinical presentation of an acute myocardial infarction. We report a case of a 77-year-old man with esophageal adenocarcinoma with local invasion of the central airways ...

journal_title：Chest

authors： Guerrero J,Majid A,Ernst A

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:COPD is a heterogeneous disease demonstrating inter-individual variation. A high COPD prevalence in Chinese populations is described, but little is known about disease clusters and prognostic outcomes in the Chinese population across Southeast Asia. We aim to determine if clusters of Chinese patients with CO...

journal_title：Chest

authors： Tiew PY,Ko FWS,Narayana JK,Poh ME,Xu H,Neo HY,Loh LC,Ong CK,Mac Aogáin M,Tan JHY,Kamaruddin NH,Sim GJH,Lapperre TS,Koh MS,Hui DSC,Abisheganaden JA,Tee A,Tsaneva-Atanasova K,Chotirmall SH

更新日期：2020-07-01 00:00:00

abstract：:Diurnal variability of peak expiratory flow rates (PEFRs) was assessed in 1,237 children. The PEFR was measured twice daily over a 1-week period. As an index of variability, the log of a week's mean of daily amplitude was calculated. Linear regression analyses revealed a significant positive association between matern...

journal_title：Chest

authors： Frischer T,Kühr J,Meinert R,Karmaus W,Urbanek R

更新日期：1993-10-01 00:00:00

abstract：:Twenty-one patients presenting with extrapulmonary sarcoidosis, 20 patients with pulmonary sarcoidosis, and 12 healthy volunteers were investigated. They were evaluated for roentgenographic findings, as well as for immunologic marker expression of cells in bronchoalveolar lavage (BAL) fluid. The patients presenting wi...

journal_title：Chest

authors： Hoogsteden HC,van Dongen JJ,Adriaansen HJ,Hooijkaas H,Delahaye M,Hop W,Hilvering C

更新日期：1988-07-01 00:00:00

abstract：STUDY OBJECTIVE:To obtain information about the diagnosis and management of primary pulmonary hypertension (PPH), especially about the use of epoprostenol (Glaxo-Wellcome; Research Triangle Park, NC) in this patient population. BACKGROUND:Long-term IV epoprostenol therapy was approved recently for use in patients with...

journal_title：Chest

authors： Robbins IM,Christman BW,Newman JH,Matlock R,Loyd JE

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:We evaluated the association between hemodynamic parameters of chronic congestive heart failure (CHF) and mediastinal lymphadenopathy (MLA) in heart transplantation (HT) candidates and the effect of HT on MLA. We also described the results of lymph node (LN) biopsies of MLA in the patients. METHODS:Patients...

journal_title：Chest

authors： Pastis NJ Jr,Van Bakel AB,Brand TM,Ravenel JG,Gilbert GE,Silvestri GA,Judson MA

更新日期：2011-06-01 00:00:00

abstract：:High-frequency jet ventilation (HFJV) is FDA-approved for ventilating patients with bronchopleural fistulae (BPF), yet little is known about its effect on the fistula airleak. We quantitated a patient's BPF airleak during both conventional volume-cycled ventilation and HFJV. The effect of chest-tube suction (CTS) on B...

journal_title：Chest

authors： Roth MD,Wright JW,Bellamy PE

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:In patients with advanced non-small cell lung cancer (NSCLC) treated with chemotherapy, we compared survival in patients with treated central airway obstruction to those who did not have central airway obstruction. METHODS:One hundred forty-four patients with advanced and inoperable NSCLC were included. Thes...

journal_title：Chest

authors： Chhajed PN,Baty F,Pless M,Somandin S,Tamm M,Brutsche MH

更新日期：2006-12-01 00:00:00

abstract：CASE PRESENTATION:A 72-year-old man underwent endoscopic resection of a 10-mm polypoid sessile lesion of the rectum. Histologic examination found a well-differentiated, low-grade (G1), neuroendocrine tumor. A thoracoabdominal CT scan was performed for staging purposes. The chest CT scan revealed a so-called cannonball-...

journal_title：Chest

authors： Scamporlino A,Mengoli MC,Calabrese O,Della Casa G,Aramini B,Spallanzani A,Morandi U,Stefani A

更新日期：2019-10-01 00:00:00

abstract：:Whole-lung lavage is the only efficient treatment in pulmonary alveolar proteinosis. A 36-year-old woman with severe pulmonary alveolar proteinosis confirmed by video-assisted thoracoscopic lung biopsies underwent repetitive whole-lung lavages without improvement. A modified technique consisting of manual ventilation ...

journal_title：Chest

authors： Bingisser R,Kaplan V,Zollinger A,Russi EW

更新日期：1998-06-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate gas exchange, pulmonary function, and lung histology during gas ventilation of the perfluorocarbon-filled lung compared with gas ventilation of the gas-filled lung in severe respiratory failure. STUDY DESIGN:Application of gas (GV) or partial liquid (PLV) ventilation in lung-injured sheep. ...

journal_title：Chest

authors： Hirschl RB,Tooley R,Parent AC,Johnson K,Bartlett RH

更新日期：1995-08-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the prevalence of thrombocytopenia in an ICU and assess which factors were associated with thrombocytopenia. DESIGN:A review of the medical records of patients admitted during 3 separate months during 1 academic year. Patients must have survived at least 12 h in the ICU. SETTING:A medical...

journal_title：Chest

authors： Baughman RP,Lower EE,Flessa HC,Tollerud DJ

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:The measurement of esophageal pressure (Pes) is the conventional method for the evaluation of the forces applied to the respiratory system by the respiratory muscles. As an alternative to Pes measurement, we propose the calculation of the instantaneous net pressure applied by the respiratory muscles [Pmusc(t)...

journal_title：Chest

authors： Iotti GA,Braschi A,Brunner JX,Palo A,Olivei MC

更新日期：1995-07-01 00:00:00

abstract：:Photoradiation therapy is a new technique being investigated for the treatment of solid malignant tumors. In this study, 17 patients with advanced, recurrent, biopsy-proven malignant lesions of the trachea or main-stem bronchus were treated by photoradiation therapy. Patients received hematoporphyrin derivative intrav...

journal_title：Chest

authors： Vincent RG,Dougherty TJ,Rao U,Boyle DG,Potter WR

更新日期：1984-01-01 00:00:00