Prolonged endurance challenge at moderate altitude: effect on serum eosinophil cationic protein, eosinophil dynamics, and lung function.

abstract：BACKGROUND:Some studies have demonstrated that the function of the growth hormone (GH)-insulin-like growth factor (IGF)-1 axis is significantly impaired in patients with oral corticosteroid (CS)-induced osteoporosis. The aim of study was to investigate the effects of long-term therapy with inhaled CSs (ICSs) on the hyp...

journal_title：Chest

authors： Malerba M,Bossoni S,Radaeli A,Mori E,Bonadonna S,Giustina A,Tantucci C

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Small cell lung carcinoma (SCLC) continues to have a poor prognosis, with a 2-year survival of < 20%. Studies have suggested that SCLC may affect the immune system to allow it to evade immunologic responses. We hypothesized that any such effect would be characterized by a decrease in the lymphoid cells assoc...

journal_title：Chest

authors： Wang W,Hodkinson P,McLaren F,Mackean MJ,Williams L,Howie SEM,Wallace WAH,Sethi T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in patients with COPD. METHODS:Serum SIRT1 protein of all samples was meas...

journal_title：Chest

authors： Yanagisawa S,Papaioannou AI,Papaporfyriou A,Baker JR,Vuppusetty C,Loukides S,Barnes PJ,Ito K

更新日期：2017-08-01 00:00:00

abstract：:Prosthetic valve endocarditis is a formidable complication following cardiac valve replacement. Surgical intervention has resulted in a significant reduction in mortality when certain complications prevail. We report two such cases of prosthetic valve endocarditis in which the use of transesophageal echocardiography p...

journal_title：Chest

authors： Bruss J,Jacobs LE,Kotler MN,Ioli AW

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a well-recognized complication of COPD. The impact of PH on exercise tolerance is largely unknown. We evaluated and compared the circulatory and ventilatory profiles during exercise in patients with COPD without PH, with moderate PH, and with severe PH. METHODS:Forty-seven pat...

journal_title：Chest

authors： Boerrigter BG,Bogaard HJ,Trip P,Groepenhoff H,Rietema H,Holverda S,Boonstra A,Postmus PE,Westerhof N,Vonk-Noordegraaf A

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Altitude exposure is associated with mild pulmonary hypertension and decreased exercise capacity. We tested the hypothesis that pulmonary vascular resistance (PVR) contributes to decreased exercise capacity in hypoxic healthy subjects. METHODS:An incremental cycle ergometer cardiopulmonary exercise test and...

journal_title：Chest

authors： Faoro V,Boldingh S,Moreels M,Martinez S,Lamotte M,Unger P,Brimioulle S,Huez S,Naeije R

更新日期：2009-05-01 00:00:00

abstract：:In this study, pleural calcifications prevailing in the inhabitants of some villages and towns around Diyarbakir, a city in southeast Turkey, have been found to be caused by the inhalation of chrysotile asbestos, the mineral commonly used indiscriminately to paint the walls and floors of houses. There were no industri...

journal_title：Chest

authors： Yazicioglu S

更新日期：1976-07-01 00:00:00

abstract：:Some macrolides have been found to exert anti-inflammatory effects. Lung diseases such as asthma, panbronchiolitis, cystic fibrosis, and bronchiectasis are thought to respond to the immunomodulatory properties of macrolides. We report three cases of idiopathic bronchiolitis obliterans organizing pneumonia, now called ...

journal_title：Chest

authors： Stover DE,Mangino D

更新日期：2005-11-01 00:00:00

abstract：:POC testing provides an opportunity for clinicians and laboratorians to work together to consider how best to serve the patients within an individual institution. Each health system has unique characteristics relative to patient population, as well as a unique laboratory structure. If physicians, nurses, laboratorians...

journal_title：Chest

authors： Kost GJ,Ehrmeyer SS,Chernow B,Winkelman JW,Zaloga GP,Dellinger RP,Shirey T

更新日期：1999-04-01 00:00:00

abstract：CASE PRESENTATION:A 61-year-old Caribbean man presented to the ED with dyspnea that had progressed over the previous week with associated cough and high fevers. Four days prior to admission, his primary care physician noted oral thrush and obtained a chest radiograph that revealed a right middle lobe infiltrate. He was...

journal_title：Chest

authors： Gong J,Melamud A,Koenig S

更新日期：2018-07-01 00:00:00

abstract：:To determine if a regimen of intravenous and oral corticosteroids reduces the relapse rate after treatment of decompensated COPD in the ED, 30 patients were studied. Forty-five visits in which intravenous and oral corticosteroids were given (T visits) were compared with an equal number of matched visits in which they ...

journal_title：Chest

authors： Murata GH,Gorby MS,Chick TW,Halperin AK

更新日期：1990-10-01 00:00:00

abstract：:Direct mechanical ventricular actuation (DMVA) is a non-blood-contacting method of biventricular cardiac massage which may be applied expediently for total circulatory support. The purpose of this study was to assess the feasibility of DMVA application for patients suffering refractory cardiac arrest. Following inform...

journal_title：Chest

authors： Anstadt MP,Bartlett RL,Malone JP,Brown GR,Martin S,Nolan DJ,Oberheu KH,Anstadt GL

更新日期：1991-07-01 00:00:00

abstract：:In summary, this is a patient who presented with respiratory acidosis and cor pulmonale. The major diagnostic challenge was in differentiating primary cardiopulmonary disease from a central abnormality of ventilatory drive. The arterial blood gases showed a normal A-a gradient suggesting hypoventilation as the etiolog...

journal_title：Chest

authors： Klepper M,Barnard P,Eschenbacher W

更新日期：1991-09-01 00:00:00

abstract：:The assessment of the structure and function of the subvalvular apparatus (SVA) in patients with rheumatic mitral stenosis (MS) is complex, yet is of major importance prior to therapeutic decision making. Currently available methods of assessment are neither sufficiently accurate nor feasible. We review anatomic and f...

journal_title：Chest

authors： Turgeman Y,Atar S,Rosenfeld T

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Vasodilatory shock refractory to catecholamine vasopressors and arginine vasopressin is highly morbid and responsible for significant mortality. Synthetic angiotensin II is a potent vasoconstrictor that may be suitable for use in these patients. RESEARCH QUESTION:What is the safety and effectiveness of angi...

journal_title：Chest

authors： Wieruszewski PM,Wittwer ED,Kashani KB,Brown DR,Butler SO,Clark AM,Cooper CJ,Davison DL,Gajic O,Gunnerson KJ,Tendler R,Mara KC,Barreto EF

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and health-care-associated pneumonia (HCAP). These infections are associated with significant morbidity, mortality, and cost. The impact of vancomycin minimum inh...

journal_title：Chest

authors： Haque NZ,Zuniga LC,Peyrani P,Reyes K,Lamerato L,Moore CL,Patel S,Allen M,Peterson E,Wiemken T,Cano E,Mangino JE,Kett DH,Ramirez JA,Zervos MJ,Improving Medicine through Pathway Assessment of Critical Therapy of Hospital-Acqu

更新日期：2010-12-01 00:00:00

abstract：STUDY OBJECTIVES:COPD patients run a risk of developing nocturnal oxygen desaturation. When evaluating patients with nocturnal hypoxemia, an unfamiliar hospital environment and the monitoring equipment may cause sleep disturbances. It was hypothesized that increased sleep disruption will lead to fewer instances of desa...

journal_title：Chest

authors： Brijker F,van den Elshout FJ,Heijdra YF,Folgering HT

更新日期：2001-06-01 00:00:00

abstract：:We describe an elderly patient with an unusual presentation of hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber disease) involving the lung. He had recurrent "pneumonia" caused by massive hemorrhage from endobronchial telangiectases. When stable, he was normoxic, had no evidence of right-to-left shunting, and ...

journal_title：Chest

authors： Lincoln MJ,Shigeoka JW

更新日期：1988-05-01 00:00:00

abstract：:The role of thoracic radiation therapy in the management of limited-stage small cell lung cancer (SCLC) is reviewed. Although chest irradiation has been used to treat SCLC for over four decades, its standard role in the management of limited-stage disease was established only during the last decade. Multiple prospecti...

journal_title：Chest

authors： Kumar P

更新日期：1997-10-01 00:00:00

abstract：:We wished to identify the physiologic abnormalities that distinguish severely breathless (SB) patients with chronic airflow limitation (CAL) from mildly breathless (MB) patients. Thirty-seven patients with stable, advanced CAL (FEV1 = 38 +/- 10 percent predicted, mean +/- SD) were separated into two distinct groups, S...

journal_title：Chest

authors： O'Donnell DE,Webb KA

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:Stenosis and occlusion rates of internal mammary artery (IMA) and saphenous vein (SV) coronary artery bypass grafts (CABGs) are markedly different, which result from respective disparities in vascular remodeling. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) regulate vascu...

journal_title：Chest

authors： Anstadt MP,Franga DL,Portik-Dobos V,Pennathur A,Bannan M,Mawulawde K,Ergul A

更新日期：2004-05-01 00:00:00

abstract：:The "elimination" of the left atrial appendage (LAA) seems to be an attractive alternative to oral anticoagulation in the treatment of atrial fibrillation, especially in patients with contraindications to oral anticoagulation therapy. The LAA, however, plays an important role in the maintenance and regulation of the c...

journal_title：Chest

authors： Stöllberger C,Schneider B,Finsterer J

更新日期：2003-12-01 00:00:00

abstract：:There is now a new pathway and examination for sleep medicine, sponsored by the American Board of Internal Medicine, and a number of accredited sleep medicine fellowship programs through the Accreditation Council for Graduate Medical Education. This review takes an historical approach to discuss the process of educati...

journal_title：Chest

authors： Strohl KP

更新日期：2011-05-01 00:00:00

abstract：:To elucidate the effect of oxitropium bromide (OTB), an anticholinergic drug, on dyspnea and gas exchange during exercise in patients with chronic obstructive pulmonary disease (COPD), we performed the cycle exercise test on 19 patients with COPD (mean age, 72.0 +/- 1.9 years; mean FEV1, 1.28 +/- 0.07 L) before and af...

journal_title：Chest

authors： Teramoto S,Fukuchi Y,Orimo H

更新日期：1993-06-01 00:00:00

abstract：:To investigate the effects of the autonomic nervous system on control of breathing, the neuromuscular (mouth occlusion pressure at 0.1 s after onset of inspiration [P0.1]) and ventilatory (minute ventilation [VE]) response to progressive hyperoxic hypercapnia was assessed in diabetic patients with autonomic dysfunctio...

journal_title：Chest

authors： Tantucci C,Scionti L,Bottini P,Dottorini ML,Puxeddu E,Casucci G,Sorbini CA

更新日期：1997-07-01 00:00:00

abstract：:We evaluated the effects of a new semisynthetic macrolide antibiotic, roxithromycin, on the bronchial hyperresponsiveness to histamine in children with asthma. Twelve hospitalized asthmatic children, aged 11 to 15 years (mean age, 12.9 years), were enrolled in this study. They were treated with 150 mg of roxithromycin...

journal_title：Chest

authors： Shimizu T,Kato M,Mochizuki H,Tokuyama K,Morikawa A,Kuroume T

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Single breath diffusing capacity for carbon monoxide (Dco) is commonly used as a simple method of assessing overall pulmonary gas exchange properties. Studies of Dco in bronchial asthma have yielded conflicting results. OBJECTIVE:To study Dco and to determine the factors influencing Dco in patients with ast...

journal_title：Chest

authors： Collard P,Njinou B,Nejadnik B,Keyeux A,Frans A

更新日期：1994-05-01 00:00:00

abstract：:Long-term oxygen is the only therapy that has been shown to improve survival in patients with chronic obstructive pulmonary disease. The aim of this study was to assess the predictors of survival in such patients treated with long-term oxygen therapy. We studied 179 patients who were assessed for long-term oxygen ther...

journal_title：Chest

authors： Skwarski K,MacNee W,Wraith PK,Sliwinski P,Zielinski J

更新日期：1991-12-01 00:00:00

abstract：:Over a 20-year period, 83 patients underwent operative pleurodesis with resection of pulmonary blebs for spontaneous pneumothorax. Follow-up for all patients was between 5 and 25 years, with a mean of 9.1 years. There were five early (5.6 percent) and three late recurrences (3.6 percent). There were no deaths or need ...

journal_title：Chest

authors： Donahue DM,Wright CD,Viale G,Mathisen DJ

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Acute myopathy following mechanical ventilation for near-fatal asthma (NFA) has been described recently, and some researchers have suggested that this complication is related to the use of neuromuscular blocking agents (NMBAs) and corticosteroids (CSs). OBJECTIVES:To determine the incidence of acute myopath...

journal_title：Chest

authors： Behbehani NA,Al-Mane F,D'yachkova Y,Paré P,FitzGerald JM

更新日期：1999-06-01 00:00:00