Bosentan decreases pulmonary vascular resistance and improves exercise capacity in acute hypoxia.

abstract：:The study objective was to assess the widespread applicability of ST/HR slope for the modified Bruce exercise test using a computerized electrocardiogram (ECG); compare the usefulness of the ST/HR slope with standard ECG criteria in detection of coronary artery disease (CAD) and identification of three-vessel or left ...

journal_title：Chest

authors： Sato I,Keta K,Aihara N,Ohe T,Shimomura K,Hasegawa Y

更新日期：1988-10-01 00:00:00

abstract：:Exercise-associated cardiac asystole (EACA) in patients without structural heart disease is uncommonly encountered. Two patients who developed prolonged asystolic arrest associated with exercise are described; both demonstrated a positive head-up tilt table response, absence of underlying heart disease, and a history ...

journal_title：Chest

authors： Tse HF,Lau CP

更新日期：1995-02-01 00:00:00

abstract：:Prosthetic valve endocarditis is a formidable complication following cardiac valve replacement. Surgical intervention has resulted in a significant reduction in mortality when certain complications prevail. We report two such cases of prosthetic valve endocarditis in which the use of transesophageal echocardiography p...

journal_title：Chest

authors： Bruss J,Jacobs LE,Kotler MN,Ioli AW

更新日期：1992-12-01 00:00:00

abstract：:A saccular aneurysm arising from the descending thoracic aorta was identified ultrasonically in a 60-year-old man with a subsequent pathologic diagnosis of a Listeria monocytogenes mycotic aneurysm. A cross-sectional scanning technique, which permitted visualization of the descending thoracic aorta in long axis, demon...

journal_title：Chest

authors： Come PC,Sacks B,Vine H,McArdle C,Koretsky S,Weintraub R

更新日期：1981-04-01 00:00:00

abstract：:There has been dramatic resurgence of interest in surgical treatment of emphysema, particularly "lung volume reduction" procedures. Recent studies have demonstrated improvements in pulmonary function, lung mechanics, exercise tolerance, and quality of life in selected patients following volume reduction procedures. Ho...

journal_title：Chest

authors： Brenner M,Yusen R,McKenna R Jr,Sciurba F,Gelb AF,Fischel R,Swain J,Chen JC,Kafie F,Lefrak SS

更新日期：1996-07-01 00:00:00

abstract：STUDY OBJECTIVES:There have been many studies on the physical characteristics at the time of contraction of a primary spontaneous pneumothorax (PSP), but it has not been shown when and how such physical characteristics develop. These issues were investigated. PATIENTS AND DESIGN:Physical development of 27 male patient...

journal_title：Chest

authors： Fujino S,Inoue S,Tezuka N,Hanaoka J,Sawai S,Ichinose M,Kontani K

更新日期：1999-10-01 00:00:00

abstract：:The prevalence of periodic limb movements (PLM) during sleep and their effect on sleep and daytime alertness were determined in 23 men with severe, stable congestive heart failure (CHF) and 9 healthy control subjects. Each subject had overnight polysomnography and the following day completed a subjective assessment of...

journal_title：Chest

authors： Hanly PJ,Zuberi-Khokhar N

更新日期：1996-06-01 00:00:00

abstract：:We present a case of successfully resected alpha-fetoprotein (AFP)-producing primary lung cancer. AFP in the serum decreased from 289 ng/ml to an undetectable level after a curative operation. The resected tumor was stained positively by the immunohistochemical study for AFP. The histologic appearance of the tumor was...

journal_title：Chest

authors： Saka H,Sakai S,Kondo N,Ito M,Shimokata K

更新日期：1988-10-01 00:00:00

abstract：:Antiphospholipid syndrome is an autoimmune disorder characterized by a hypercoagulable state, leading to arterial and venous thrombosis. We present a 23-year-old patient, suspected of having Budd-Chiari syndrome due to antiphospholipid syndrome, who developed severe and progressive hypoxemia, requiring prolonged mecha...

journal_title：Chest

authors： Bunge JJH,Wiersema US,Moelker A,van Bommel J,Tjwa ETTL

更新日期：2014-11-01 00:00:00

abstract：:Superior vena caval (SVC) syndrome may be caused by extravascular compression or intravascular obstruction. Knowing the mechanism of SVC syndrome enables the physician to choose appropriate treatment. Transesophageal echocardiography (TEE) is a safe bedside procedure that is excellent for evaluating the SVC and its su...

journal_title：Chest

authors： Ayala K,Chandrasekaran K,Karalis DG,Parris TM,Ross JJ Jr

更新日期：1992-03-01 00:00:00

abstract：:Most panels that develop clinical practice guidelines are poorly equipped to address resource allocation or cost issues associated with management options. This risks neglect, arbitrariness, lack of transparency, and methodological flaws in consideration of resource allocation. We provide recommendations for guideline...

journal_title：Chest

authors： Guyatt G,Baumann M,Pauker S,Halperin J,Maurer J,Owens DK,Tosteson AN,Carlin B,Gutterman D,Prins M,Lewis SZ,Schünemann H

更新日期：2006-01-01 00:00:00

abstract：:The purpose of this study was to determine the incidence and severity of obstructive events and oxyhemoglobin desaturation (dSaO2) in 37 patients with paralytic/restrictive ventilatory insufficiency during use of nocturnal ventilatory assistance provided by means of negative-pressure body ventilators (BVs). Thirteen o...

journal_title：Chest

authors： Bach JR,Penek J

更新日期：1991-06-01 00:00:00

abstract：:We describe two patients with AIDS who developed new diffuse pulmonary infiltrates during the course of their hospitalization. In both cases, the infiltrates were attributed to pulmonary hemorrhage complicating an existing condition rather than representing a new pulmonary process. Identification of pulmonary hemorrha...

journal_title：Chest

authors： Koziel H,Haley K,Nasser I,Filderman AE

更新日期：1994-12-01 00:00:00

abstract：:Three sets of guidelines for the management of COPD that are widely recognized (from the European Respiratory Society [ERS], American Thoracic Society [ATS], and British Thoracic Society [BTS]) are reviewed and compared. None of the documents uses classic evidence-based documentation, and, in many instances, the recom...

journal_title：Chest

authors： Ferguson GT

更新日期：2000-02-01 00:00:00

abstract：:We describe the cases of three women with pulmonary involvement in the eosinophilia-myalgia syndrome. The illness was characterized by elevated peripheral blood eosinophil counts, myalgias, fatigue, and dyspnea. Two of three patients had bilateral infiltrates on chest roentgenograms. All three had markedly decreased c...

journal_title：Chest

authors： Catton CK,Elmer JC,Whitehouse AC,Clode JB,Hustrulid RI

更新日期：1991-02-01 00:00:00

abstract：:On the occasion of this Fourth World Conference on Lung Cancer, I am privileged to present the opening keynote address. This presentation has been sponsored by the Ontario Cancer Treatment and Research Foundation. In 1952, the Foundation established an annual lectureship in memory of one of their prominent physicians....

journal_title：Chest

authors： Pearson FG

更新日期：1986-04-01 00:00:00

abstract：:Bronchial epithelial damage and mucus hypersecretion are characteristic features of chronic airway inflammation that can impair mucociliary clearance and can cause recurrent or persistent respiratory infection. In response to chemoattractants produced by damaged or inflamed tissue, neutrophils move through sequential ...

journal_title：Chest

authors： Tamaoki J

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:The literature on preoperative smoking cessation indicates that smoking patients are more likely to have postoperative complications. However, the economic implications of such complications are unclear. In particular, the balance between the cost of a preoperative intervention for smoking cessation (PISC) a...

journal_title：Chest

authors： Hejblum G,Atsou K,Dautzenberg B,Chouaid C

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:It is unclear whether an abnormal swallowing reflex affects COPD exacerbations. This study investigated the prevalence of abnormal swallowing reflexes and its relationship with COPD exacerbation prospectively. We also clarified its association with gastroesophageal reflux disease (GERD) and airway bacterial ...

journal_title：Chest

authors： Terada K,Muro S,Ohara T,Kudo M,Ogawa E,Hoshino Y,Hirai T,Niimi A,Chin K,Mishima M

更新日期：2010-02-01 00:00:00

abstract：:Central hemodynamics and gas exchange were studied in six patients with chronic obstructive pulmonary disease (mean age, 60 years). Patients were selected for the study if the volume of blood was 1 L larger than the predicted normal value, if there was no history of infection, and if no drug assumed to influence pulmo...

journal_title：Chest

authors： Gertz I,Hedenstierna G,Wester PO

更新日期：1979-02-01 00:00:00

abstract：:Normal subjects were exposed to an aerosol of Escherichia coli endotoxin. Carbon monoxide diffusion (Dco), spirometry, blood neutrophils, white blood cells, and platelets were determined at various times thereafter. A significant decrease in Dco and an increase in blood neutrophils was found, with a maximum effect 4 t...

journal_title：Chest

authors： Herbert A,Carvalheiro M,Rubenowitz E,Bake B,Rylander R

更新日期：1992-10-01 00:00:00

abstract：:Although the relationship between blood pressure and cardiac performance has been widely recognized, there are few published clinical observations concerning the effect of blood pressure control on cardiac function. We evaluated the effect of prazosin, an antihypertensive agent which also improves hemodynamic measurem...

journal_title：Chest

authors： Massie BM,Chan S

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Little is known about the association between left ventricular (LV) diastolic dysfunction and outcomes in patients with idiopathic or heritable pulmonary arterial hypertension (PAH). Our rationale was to investigate the prevalence of LV diastolic dysfunction, and its association with disease severity and out...

journal_title：Chest

authors： Tonelli AR,Plana JC,Heresi GA,Dweik RA

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is recognized as a stroke risk factor in atrial fibrillation (AF). Patients with diabetes with retinopathy have an increased risk for systemic cardiovascular complications, and severe diabetic retinopathy predisposes to ocular bleeding. We hypothesized that patients with diabetes, retinopat...

journal_title：Chest

authors： Lip GYH,Clementy N,Pierre B,Boyer M,Fauchier L

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:It has been postulated that differences in provocative concentration of methacholine causing a 20% fall in FEV1 (PC20) values between the dosimeter method and tidal breathing method might be due to differences in the dose of agonist delivered to the mouth. The aim of the present study was to determine the in...

journal_title：Chest

authors： Prieto L,Lopez V,Llusar R,Rojas R,Marin J

更新日期：2008-10-01 00:00:00

abstract：:Irradiation therapy for lung cancer is mostly restricted to conventional methods. To improve therapeutic ratio, we have combined a treatment planning and a gene therapy approach. Three-dimensional conformal radiotherapy is described as carried out by methods of gene therapy for radiation protection using the manganese...

journal_title：Chest

authors： Greenberger JS,Bahri S,Jett J,Belani C,Kalend A,Epperly M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:IV fluid represents a basic therapeutic intervention for septic shock. Unfortunately, the optimal administration of IV fluid to maximize patient outcomes and prevent complications is largely unknown. METHODS:Patients with septic shock admitted to the medical ICUs of Barnes-Jewish Hospital (January to Decemb...

journal_title：Chest

authors： Chen C,Kollef MH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:International time trends in asthma mortality have played an important sentinel role in the identification of two epidemics of asthma mortality in some countries in the 1960s and the 1970s and 1980s. Since then, little attention has been paid to the ongoing international time trends. METHODS:Country-specifi...

journal_title：Chest

authors： Wijesinghe M,Weatherall M,Perrin K,Crane J,Beasley R

更新日期：2009-04-01 00:00:00

abstract：:Fluid infusion may be lifesaving in patients with severe sepsis, especially in the earliest phases of treatment. Following initial resuscitation, however, fluid boluses often fail to augment perfusion and may be harmful. In this review, we seek to compare and contrast the impact of fluids in early and later sepsis; sh...

journal_title：Chest

authors： Durairaj L,Schmidt GA

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Male sex is an independent predictor of worse survival in pulmonary arterial hypertension (PAH). This finding might be explained by more severe pulmonary vascular disease, worse right ventricular (RV) function, or different response to therapy. The aim of this study was to investigate the underlying cause of...

journal_title：Chest

authors： Jacobs W,van de Veerdonk MC,Trip P,de Man F,Heymans MW,Marcus JT,Kawut SM,Bogaard HJ,Boonstra A,Vonk Noordegraaf A

更新日期：2014-06-01 00:00:00