Fluid therapy in resuscitated sepsis: less is more.

abstract：BACKGROUND:Current functional assessments do not allow a reliable assessment of small airways, which are a major site of disease in COPD. Single-breath washout (SBW) tests are feasible and reproducible methods for evaluating small airway disease. Their relevance in COPD remains unknown. METHODS:We performed a cross-se...

journal_title：Chest

authors： Boeck L,Gensmer A,Nyilas S,Stieltjes B,Re TJ,Tamm M,Latzin P,Stolz D

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Rhinovirus (RV)-induced pulmonary exacerbations are common in cystic fibrosis (CF) and have been associated with impaired virus clearance by the CF airway epithelium in vitro. Here, we assess in vivo the association of RV prevalence and load with antiviral defense mechanisms, airway inflammation, and lung fu...

journal_title：Chest

authors： Kieninger E,Singer F,Tapparel C,Alves MP,Latzin P,Tan HL,Bossley C,Casaulta C,Bush A,Davies JC,Kaiser L,Regamey N

更新日期：2013-03-01 00:00:00

abstract：:An original method of treatment for main bronchus fistula occurring after pneumonectomy was described in 1961. The operation is performed via a median sternotomy and the carinal region exposed. The main bronchi can then be divided in an area not involved with infection. We describe ten patients who underwent this proc...

journal_title：Chest

authors： Beltrami V

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVES:Primary pulmonary hypertension (PPH) is a pulmonary vasculopathy resulting in exercise intolerance, usually due to dyspnea. We hypothesized that ventilation is increased during exercise in PPH relative to normal because the ventilated lung is underperfused, cardiac output increase is restricted, and arterial...

journal_title：Chest

authors： Yasunobu Y,Oudiz RJ,Sun XG,Hansen JE,Wasserman K

更新日期：2005-05-01 00:00:00

abstract：:Primary pulmonary hypertension (PPH) is a serious pulmonary vascular disease occurring mostly in adult women. Although its occurrence in families was reported within a few years after the original clinical report, PPH was formerly believed rarely to have a genetic basis. Recent progress has not only clarified a basic ...

journal_title：Chest

authors： Loyd JE

更新日期：2002-12-01 00:00:00

abstract：:These data suggest that the alveolar lining layer and lamellar body membranes contain the same saline-insoluble proteins, two of which are unusual in that they contain hydroxyproline and large amounts of glycine. Neither the function nor the origin of these glycopeptides has been established, and we are currently eval...

journal_title：Chest

authors： Passero MA,Bhattacharyya SN,Sahu S,Lynn WS

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Recent studies have implicated the 5-lipoxygenase/leukotriene (LT) pathway in cardiovascular disease (CVD), which may have important implications for asthmatics because several drugs that target this pathway are currently used to treat asthma. We sought to determine whether montelukast, a cysteinyl LT antago...

journal_title：Chest

authors： Allayee H,Hartiala J,Lee W,Mehrabian M,Irvin CG,Conti DV,Lima JJ

更新日期：2007-09-01 00:00:00

abstract：:Due to concerns about the efficacy and safety of using pulmonary artery catheterization to evaluate hemodynamic status, noninvasive diagnostic testing has gained increased importance. This article focuses on both the supportive evidence and the limitations of applying the vascular pedicle width (VPW), which is the med...

journal_title：Chest

authors： Ely EW,Haponik EF

更新日期：2002-03-01 00:00:00

abstract：UNLABELLED:Formoterol solution aerosol has proved to be a fast and long-acting beta 2-sympathicomimetic drug in many clinical trials. The physical stability, however, was such that storage needed to be at 4 degrees C to 8 degrees C before first use; afterwards, the aerosol could be used for another three months at room...

journal_title：Chest

authors： Maesen FP,Nakratzas G,Bantje TA,Prins J,Zweers PG

更新日期：1992-11-01 00:00:00

abstract：:We reviewed results of 78 diagnostic thoracoscopic examinations of patients with lung cancer and homolateral pleural effusion. The study stresses the main locations of pleural metastasis in cases of lung cancer and correlates these data with the pleural spread from extrathoracic primary neoplasms. Also pointed out is ...

journal_title：Chest

authors： Cantó A,Ferrer G,Romagosa V,Moya J,Bernat R

更新日期：1985-05-01 00:00:00

abstract：:The efficacy of bronchoscopy for the diagnosis of tuberculosis in patients infected with human immunodeficiency virus (HIV) has not been systematically evaluated. We therefore compared the diagnostic yield of bronchoscopy in 67 HIV-infected and 45 non-HIV-infected patients with culture-proven pulmonary tuberculosis. I...

journal_title：Chest

authors： Kennedy DJ,Lewis WP,Barnes PF

更新日期：1992-10-01 00:00:00

abstract：:The clinical course of congestive heart failure (CHF) and mitral valve stenosis (MVS) is accompanied by episodes of dyspnea, wheezing, and cough, symptoms also observed in patients with bronchial hyperreactivity. However, it is still controversial whether bronchial hyperreactivity is demonstrable in patients with chro...

journal_title：Chest

authors： Brunnée T,Graf K,Kastens B,Fleck E,Kunkel G

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the costs, consequences, effectiveness, and safety of ciprofloxacin vs standard antibiotic care in patients with an initial acute exacerbation of chronic bronchitis (AECB) as well as recurrent AECBs over a 1-year period. DESIGN:Randomized, multicenter, parallel-group, open-label study. SETTING:O...

journal_title：Chest

authors： Grossman R,Mukherjee J,Vaughan D,Eastwood C,Cook R,LaForge J,Lampron N

更新日期：1998-01-01 00:00:00

abstract：:The aim of this study was to investigate whether the demonstration of plasma cells (PC), which are normally absent in bronchoalveolar lavage (BAL) fluid, facilitates differentiation among pulmonary disorders. Initial BAL fluid samples of 1,260 patients were analyzed. In 83 of these, PC were found. Of these 83, 47 were...

journal_title：Chest

authors： Drent M,van Velzen-Blad H,Diamant M,Wagenaar SS,Donckerwolck-Bogaert M,van den Bosch JM

更新日期：1993-06-01 00:00:00

abstract：:Renin-angiotensin system activation is suspected of being involved in postcoronary surgery hypertension, but appears to be useful in maintaining blood pressure during anesthesia and cardiopulmonary bypass. To clarify these points, 19 patients were compared: ten as a control group and nine who received captopril during...

journal_title：Chest

authors： Colson P,Grolleau D,Chaptal PA,Ribstein J,Mimran A,Roquefeuil B

更新日期：1988-06-01 00:00:00

abstract：:A case of amiodarone pulmonary toxicity (APT) occurring within days of the start of therapy and presenting with hemoptysis is reported. Both the very early onset and the presenting symptom are highly unusual in this entity. Implications in the diagnosis of APT are discussed. ...

journal_title：Chest

authors： Goldstein I,Topilsky M,Segev D,Isakov A,Heller I

更新日期：1997-05-01 00:00:00

abstract：STUDY OBJECTIVE:Laboratory testing plays a minor role in the assessment of aortic dissection. Its main value is in the exclusion of other diseases. Following an incidental observation, we systematically investigated the relationship between elevated d-dimer levels and acute aortic dissection. DESIGN:We prospectively t...

journal_title：Chest

authors： Weber T,Högler S,Auer J,Berent R,Lassnig E,Kvas E,Eber B

更新日期：2003-05-01 00:00:00

abstract：STUDY OBJECTIVES:Although percutaneous transluminal coronary angioplasty (PTCA) is known to have beneficial effects on exercise capacity, its effects on the cardiovascular response during the onset of exercise have not been clarified. The present study was undertaken to determine the effects of PTCA on the kinetics of ...

journal_title：Chest

authors： Adachi H,Koike A,Niwa A,Sato A,Takamoto T,Marumo F,Hiroe M

更新日期：2000-08-01 00:00:00

abstract：:The Resource-Based Relative Value Scale (RBRVS) is fundamentally undermined by the following foundational errors: (1) The full range of office-based evaluation and management (E/M) activities are not captured by the Current Procedural Terminology (CPT) code choices, (2) it places relatively high values on procedural s...

journal_title：Chest

authors： Kumetz EA,Goodson JD

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) has been reported to be associated with increased values of exhaled nitric oxide (ENO), which could not be entirely explained by the association between CRS and asthma. The aim of this study was to investigate the variables associated with increased ENO in patients with CRS. MET...

journal_title：Chest

authors： Guida G,Rolla G,Badiu I,Marsico P,Pizzimenti S,Bommarito L,De Stefani A,Usai A,Bugiani M,Malinovschi A,Bucca C,Heffler E

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The use of both heroin and cocaine has been associated with asthma exacerbations. However, the magnitude of this effect has not been adequately described. The purpose of this study was to examine the association between cocaine or heroin use and asthma severity. METHODS:We conducted a retrospective chart re...

journal_title：Chest

authors： Levine M,Iliescu ME,Margellos-Anast H,Estarziau M,Ansell DA

更新日期：2005-10-01 00:00:00

abstract：:The clinical, roentgenographic and laboratory findings, their relationship to each other and to the subsequent hospital course are reported for 14 victims of gaseous ammonia inhalation. Initial physical examination enabled differentiation of a mildly affected from a moderately affected group, but patients in both grou...

journal_title：Chest

authors： Montague TJ,Macneil AR

更新日期：1980-04-01 00:00:00

abstract：:An unruptured aneurysm of the left sinus of Valsalva was diagnosed by angiography in a 16-year-old male subject 19 years ago. A recent repeated angiographic study documented no change in the aneurysm over the 19-year interval, and the patient has remained asymptomatic. We are aware of no other long-term follow-up repo...

journal_title：Chest

authors： Martin LW,Hsu I,Schwartz H,Wasserman AG

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Pleural effusions frequently accumulate in patients with left-sided heart failure. However, our recent study in patients with idiopathic and heritable pulmonary arterial hypertension (PAH) demonstrated that pleural effusions frequently occur in patients with isolated right-sided heart failure (RHF). The obje...

journal_title：Chest

authors： Luo YF,Robbins IM,Karatas M,Brixey AG,Rice TW,Light RW

更新日期：2011-07-01 00:00:00

abstract：STUDY OBJECTIVE:We conducted the first randomized controlled study to assess the effects of short-term 28% and 100% oxygen on PaCO(2) and peak expiratory flow rate (PEFR) in patients with acute severe asthma. PATIENTS AND INTERVENTIONS:Seventy-four patients (mean age, 37.9 +/- 9.7 years [+/- SD]; PEFR, 41.0 +/- 12.1% ...

journal_title：Chest

authors： Rodrigo GJ,Rodriquez Verde M,Peregalli V,Rodrigo C

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Changes in Paco(2) have not been described during thoracoscopy under sedation-assisted local anesthesia. We hypothesized that hypoventilation might occur secondary to administration of sedatives and decreased ventilation in one lung. AIM:Prospectively measure cutaneous carbon dioxide tension (Pcco(2)) in ad...

journal_title：Chest

authors： Chhajed PN,Kaegi B,Rajasekaran R,Tamm M

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:To compare the systemic bioavailability (assessed by cortisol suppression) of high-dose budesonide when given by four inhaler devices and orally. Also studied are the relative systemic potencies of three inhaled steroids (budesonide, fluticasone propionate, and beclomethasone dipropionate) when given by mete...

journal_title：Chest

authors： Wales D,Makker H,Kane J,McDowell P,O'Driscoll BR

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with 3 to 5 years' survival. Although FVC is used to assess disease progression and treatment response, identifying predictive circulating blood biomarkers could help identify specific biologic pathways for treatment. An international, prospective, ...

journal_title：Chest

authors： Raghu G,Richeldi L,Jagerschmidt A,Martin V,Subramaniam A,Ozoux ML,Esperet CA,Soubrane C

更新日期：2018-12-01 00:00:00

abstract：:A retrospective study of 34 patients (33 male and one female) was conducted to evaluate a potential correlation between patient survival, propensity to metastasize and specific subtypes of pulmonary adenocarcinomas as determined by ultrastructural examination. Previous electron microscopic studies of pulmonary adenoca...

journal_title：Chest

authors： Herrera GA,Alexander CB,DeMoraes HP

更新日期：1983-11-01 00:00:00

abstract：:We tested the response characteristics of a dual transcutaneous (tc) PO2/PCO2 monitoring system in healthy subjects who breathed various gas mixtures, and we compared steady-state tc readings to simultaneous arterial blood gas analysis in 20 stable respiratory outpatients. The electrodes were simple to apply, required...

journal_title：Chest

authors： Kesten S,Chapman KR,Rebuck AS

更新日期：1991-05-01 00:00:00