Abstract:
:There has been dramatic resurgence of interest in surgical treatment of emphysema, particularly "lung volume reduction" procedures. Recent studies have demonstrated improvements in pulmonary function, lung mechanics, exercise tolerance, and quality of life in selected patients following volume reduction procedures. However, considerable uncertainty remains regarding overall benefit, optimal patient selection, operative techniques, and duration of response. This summarizes current approaches to lung volume reduction surgery, available clinical outcome information, selection criteria, and physiologic mechanisms of response, and discusses the potential role for surgical volume reduction in treatment of emphysema. Recent data appear to support the efficacy of bilateral staple lung volume reduction surgery in patients with severe symptomatic heterogeneously distributed emphysema. Further studies will be needed to determine relative value of different operative techniques and benefit in patients with other clinical presentations.
journal_name
Chestjournal_title
Chestauthors
Brenner M,Yusen R,McKenna R Jr,Sciurba F,Gelb AF,Fischel R,Swain J,Chen JC,Kafie F,Lefrak SSdoi
10.1378/chest.110.1.205subject
Has Abstractpub_date
1996-07-01 00:00:00pages
205-18issue
1eissn
0012-3692issn
1931-3543pii
S0012-3692(15)46305-6journal_volume
110pub_type
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