The clinical profile of unresolved pulmonary embolism.

Abstract:

:Nearly all patients with pulmonary embolism (PE) have complete clinical and hemodynamic and at least near complete roentgenographic and angiographic resolution within four to six weeks of the acute event. To classify the syndrome of unresolved pulmonary embolism we reviewed our experience and that of the English literature to extract 30 well-described cases. The mean age at presentation was 45 years, and most patients were less than 60 years old. Almost all complained of dyspnea, and the majority had at least one clinical event suggestive of PE. Most had clinical evidence of pulmonary hypertension. Roentgenographic, arterial blood gas and electrocardiographic findings were nonspecific, though the perfusion lung scan was always abnormal. Most patients exhibited mild-to-moderate pulmonary hypertension. The severity of pulmonary artery obstruction was quite variable and did not correlate with the magnitude of arterial hypoxemia or pulmonary hypertension. Most patients did not improve with long-term anticoagulation therapy and underwent pulmonary embolectomy with acceptable mortality. Postoperative improvement correlated with improved arterial blood gas levels, abatement of pulmonary hypertension, and more satisfactory pulmonary perfusion.

journal_name

Chest

journal_title

Chest

authors

Benotti JR,Ockene IS,Alpert JS,Dalen JE

doi

10.1378/chest.84.6.669

subject

Has Abstract

pub_date

1983-12-01 00:00:00

pages

669-78

issue

6

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(15)37024-0

journal_volume

84

pub_type

杂志文章

相关文献

CHEST文献大全
  • Doxycycline pleurodesis for pneumothorax in patients with AIDS.

    abstract::Since first described in 1984, nontraumatic pneumothoraces in patients with AIDS has become more common. When compared with spontaneous pneumothorax in the general population, pneumothoraces in patients with AIDS are often complicated by prolonged air leaks as well as higher recurrence rates. Chemical pleurodesis has ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.105.3.823

    authors: Read CA,Reddy VD,O'Mara TE,Richardson MS

    更新日期:1994-03-01 00:00:00

  • Midterm clinical results in myocardial revascularization using the radial artery.

    abstract:STUDY OBJECTIVES:The aim of this study was to evaluate the immediate and midterm results of coronary artery bypass grafting with the radial artery (RA) as a conduit. PATIENTS:Two hundred forty-one patients underwent myocardial revascularization using the RA. In 78.5% of patients, three coronary vessels were involved, ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.122.6.2075

    authors: Beghi C,Nicolini F,Budillon AM,Borrello B,Ballore L,Reverberi C,Gherli T

    更新日期:2002-12-01 00:00:00

  • The Vital Capacity Is Vital: Epidemiology and Clinical Significance of the Restrictive Spirometry Pattern.

    abstract::Epidemiologic research has revealed a substantial portion of the general population with abnormal spirometry results that are characterized by decreased FEV1 and FVC but a preserved FEV1/FVC ratio. This restrictive spirometry pattern (RSP) is inconsistently defined in the literature and not well addressed by current g...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.15-1045

    authors: Godfrey MS,Jankowich MD

    更新日期:2016-01-01 00:00:00

  • Tamponade: Hemodynamic and Echocardiographic Diagnosis.

    abstract::Cardiac tamponade is a medical emergency that can be readily reversed with timely recognition and appropriate intervention. The clinical diagnosis of cardiac tamponade requires synthesis of a constellation of otherwise nonspecific features based on an understanding of the underlying pathophysiological characteristics....

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1016/j.chest.2017.11.003

    authors: Kearns MJ,Walley KR

    更新日期:2018-05-01 00:00:00

  • Lung ultrasound in the diagnosis and follow-up of community-acquired pneumonia: a prospective, multicenter, diagnostic accuracy study.

    abstract:BACKGROUND:The aim of this prospective, multicenter study was to define the accuracy of lung ultrasound (LUS) in the diagnosis of community-acquired pneumonia (CAP). METHODS:Three hundred sixty-two patients with suspected CAP were enrolled in 14 European centers. At baseline, history, clinical examination, laboratory ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1378/chest.12-0364

    authors: Reissig A,Copetti R,Mathis G,Mempel C,Schuler A,Zechner P,Aliberti S,Neumann R,Kroegel C,Hoyer H

    更新日期:2012-10-01 00:00:00

  • Breathlessness in patients with severe chronic airflow limitation. Physiologic correlations.

    abstract::We wished to identify the physiologic abnormalities that distinguish severely breathless (SB) patients with chronic airflow limitation (CAL) from mildly breathless (MB) patients. Thirty-seven patients with stable, advanced CAL (FEV1 = 38 +/- 10 percent predicted, mean +/- SD) were separated into two distinct groups, S...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.3.824

    authors: O'Donnell DE,Webb KA

    更新日期:1992-09-01 00:00:00

  • Predictors of symptoms are different from predictors of severe exacerbations from asthma in children.

    abstract:BACKGROUND:Asthma therapy is typically prescribed and titrated based on patient or parent self-report of symptoms. No longitudinal studies have assessed the relationship between symptoms and severe asthma exacerbations in children. The goal of our study was (1) to assess the association of asthma symptoms with severe a...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1378/chest.10-2794

    authors: Wu AC,Tantisira K,Li L,Schuemann B,Weiss ST,Fuhlbrigge AL,Childhood Asthma Management Program Research Group.

    更新日期:2011-07-01 00:00:00

  • Integration of clinical and hemodynamic parameters in the prediction of long-term survival in patients with pulmonary arterial hypertension.

    abstract:BACKGROUND:Current management guidelines for pulmonary arterial hypertension (PAH) recommend a treatment choice based primarily on World Health Organization (WHO) functional class. This study was designed to assess how the incorporation of readily obtained clinical and test-based information may significantly improve t...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.10-1293

    authors: Kane GC,Maradit-Kremers H,Slusser JP,Scott CG,Frantz RP,McGoon MD

    更新日期:2011-06-01 00:00:00

  • How Common Is Airflow Limitation in Patients With Emphysema on CT Scan of the Chest?

    abstract:BACKGROUND:COPD has traditionally been defined by the presence of irreversible airflow limitation on spirometry using either the GOLD (Global Initiative for Chronic Obstructive Lung Disease) or American Thoracic Society/European Respiratory Society criteria (lower limit of normal [LLN]). We have observed that some pati...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.14-1556

    authors: Lutchmedial SM,Creed WG,Moore AJ,Walsh RR,Gentchos GE,Kaminsky DA

    更新日期:2015-07-01 00:00:00

  • Improved left ventricular relaxation during short-term right ventricular outflow tract compared to apical pacing.

    abstract:STUDY OBJECTIVES:Pacing-induced asynchrony may deteriorate left ventricular function; however, limited data exists in humans. The aim of our study was to compare left ventricular hemodynamics during short-term atrioventricular sequential pacing from the right ventricular apex and from the outflow tract of the right ven...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.117.1.60

    authors: Kolettis TM,Kyriakides ZS,Tsiapras D,Popov T,Paraskevaides IA,Kremastinos DT

    更新日期:2000-01-01 00:00:00

  • Airway cooling and nocturnal asthma.

    abstract::It has long been recognized that asthma often worsens at night. The nature of nocturnal asthma is unclear. Previously we have demonstrated that acute asthma attacks can be induced by exposing the body to cold, and that such attacks can be prevented by breathing warm, humidified air (WHA). Since body temperature begins...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.81.6.675

    authors: Chen WY,Chai H

    更新日期:1982-06-01 00:00:00

  • Development of a giant bulla after lung volume reduction surgery.

    abstract::Lung volume reduction surgery (LVRS) is being evaluated in the treatment of emphysema. The proposed mechanisms of improvement are increased elastic recoil of the lung and improved mechanical efficiency of the muscles of respiration. We report a unique patient with emphysema who developed a giant bulla 3 years subseque...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.116.6.1809

    authors: Iqbal M,Rossoff L,McKeon K,Graver M,Scharf SM

    更新日期:1999-12-01 00:00:00

  • A Randomized Trial of Initiation of Chronic Noninvasive Mechanical Ventilation at Home vs In-Hospital in Patients With Neuromuscular Disease and Thoracic Cage Disorder: The Dutch Homerun Trial.

    abstract:BACKGROUND:There is an increasing demand for home mechanical ventilation (HMV) in patients with chronic respiratory insufficiency. At present, noninvasive ventilation is exclusively initiated in a clinical setting at all four centers for HMV in the Netherlands. In addition to its high societal costs and patient discomf...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.07.007

    authors: van den Biggelaar RJM,Hazenberg A,Cobben NAM,Gaytant MA,Vermeulen KM,Wijkstra PJ

    更新日期:2020-12-01 00:00:00

  • Immunosuppressive therapy in connective tissue diseases-associated pulmonary arterial hypertension.

    abstract:STUDY OBJECTIVE:Immune and inflammatory mechanisms could play a significant role in pulmonary arterial hypertension (PAH) genesis or progression, especially in patients with connective tissue diseases. Immunosuppressive therapy should be better evaluated in this setting. STUDY DESIGN:Monocentric retrospective study. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.130.1.182

    authors: Sanchez O,Sitbon O,Jaïs X,Simonneau G,Humbert M

    更新日期:2006-07-01 00:00:00

  • Hypoxemia in acute pulmonary embolism.

    abstract::Most patients with severe, acute pulmonary embolism (PE) have arterial hypoxemia. To further define the respective roles of ventilation to perfusion (VA/Q) mismatch and intrapulmonary shunt in the mechanism of hypoxemia, we used both right heart catheterization and the six inert gas elimination technique in seven pati...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.88.6.829

    authors: Huet Y,Lemaire F,Brun-Buisson C,Knaus WA,Teisseire B,Payen D,Mathieu D

    更新日期:1985-12-01 00:00:00

  • Differences in end-of-life care in the ICU across patients cared for by medicine, surgery, neurology, and neurosurgery physicians.

    abstract:BACKGROUND:Some of the challenges in the delivery of high-quality end-of-life care in the ICU include the variability in the characteristics of patients with certain illnesses and the practice of critical care by different specialties. METHODS:We examined whether ICU attending specialty was associated with quality of ...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.13-1351

    authors: Kross EK,Engelberg RA,Downey L,Cuschieri J,Hallman MR,Longstreth WT Jr,Tirschwell DL,Curtis JR

    更新日期:2014-02-01 00:00:00

  • Threshold pressure training, breathing pattern, and exercise performance in chronic airflow obstruction.

    abstract::The effects of six weeks of threshold pressure inspiratory muscle training (IMT) on inspiratory muscle performance, breathing pattern and exercise performance were studied in eight patients with severe airflow obstruction. The results indicated that IMT improved inspiratory muscle performance but did not affect exerci...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.95.3.535

    authors: Flynn MG,Barter CE,Nosworthy JC,Pretto JJ,Rochford PD,Pierce RJ

    更新日期:1989-03-01 00:00:00

  • Sleep Duration and Efficiency Associated With Better Functional Exercise Capacity in Black Smokers at Risk for COPD.

    abstract:BACKGROUND:Black smokers have earlier development of lung disease as well as poorer sleep health than whites. RESEARCH QUESTION:In a sample of black smokers, to what extent does sleep health modify the association between smoking level and functional exercise capacity? DESIGN AND METHODS:Cross-sectional data from 209...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2020.03.070

    authors: Gangemi AJ,Satti A,Zantah M,Blair R,Brewer B,Ma G,Grandner MA,Davey A,Criner GJ,Patterson F

    更新日期:2020-10-01 00:00:00

  • Pseudopseudotumor of the lung. Hepatic herniation into the right major fissure imitating a pseudotumor on chest roentgenogram.

    abstract::A young man presented to us with an asymptomatic ovoid mass which appeared to be in the right major fissure. The roentgenographic appearance of the lesion was that of a pseudotumor. The computerized tomography scan suggested tissue density leading to exploration. At surgery, we found the mass to be a portion of liver ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.78.2.346

    authors: Fanta CH,Kacoyanis GP,Koster JK Jr,McFadden ER Jr

    更新日期:1980-08-01 00:00:00

  • Lack of efficacy for a cervicomandibular support collar in the management of obstructive sleep apnea.

    abstract:STUDY OBJECTIVES:The effect of therapy using a cervicomandibular support collar (CMSC) to manage obstructive sleep apnea (OSA) was compared with standard therapy, nasal continuous positive airway pressure (nCPAP). DESIGN:Subjects received treatment with CMSC or nCPAP each for 1 month in random order. The study was ana...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.125.1.118

    authors: Skinner MA,Kingshott RN,Jones DR,Taylor DR

    更新日期:2004-01-01 00:00:00

  • International trends in asthma mortality rates in the 5- to 34-year age group: a call for closer surveillance.

    abstract:BACKGROUND:International time trends in asthma mortality have played an important sentinel role in the identification of two epidemics of asthma mortality in some countries in the 1960s and the 1970s and 1980s. Since then, little attention has been paid to the ongoing international time trends. METHODS:Country-specifi...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.08-2082

    authors: Wijesinghe M,Weatherall M,Perrin K,Crane J,Beasley R

    更新日期:2009-04-01 00:00:00

  • Early diagnosis and estimation of pulmonary congestion and edema in patients with left-sided heart diseases from histogram of pulmonary CT number.

    abstract::To establish an early diagnosis and have a quantitative estimation of congestion or edema, pulmonary CT scans were performed to detect the increase of regional lung water volume of patients with congestive heart failure. CT scanning of the upper, middle, and lower lung fields at maximum inspiration and hemodynamic ana...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.109.6.1439

    authors: Kato S,Nakamoto T,Iizuka M

    更新日期:1996-06-01 00:00:00

  • The effects of macrolides on inflammatory cells.

    abstract::Bronchial epithelial damage and mucus hypersecretion are characteristic features of chronic airway inflammation that can impair mucociliary clearance and can cause recurrent or persistent respiratory infection. In response to chemoattractants produced by damaged or inflamed tissue, neutrophils move through sequential ...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.125.2_suppl.41s

    authors: Tamaoki J

    更新日期:2004-02-01 00:00:00

  • An unusual cause of respiratory alkalosis.

    abstract::A 56-year-old man with a longstanding tracheostomy presented to the hospital with upper GI bleeding and was found to have a profound respiratory alkalosis. The cause of this patient's involuntary hyperventilation was hiccuping complicated by the absence of glottic closure. ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.100.4.1159

    authors: Campbell LA,Schwartz SH

    更新日期:1991-10-01 00:00:00

  • Relationship between ICU design and mortality.

    abstract:BACKGROUND:Architectural design of health-care facilities can influence patient safety; however, it is unknown whether patient outcomes are significantly affected by ICU design. METHODS:Six hundred sixty-four patients admitted to the medical ICU (MICU) of Columbia University Medical Center during 2008 were included in...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.09-1458

    authors: Leaf DE,Homel P,Factor PH

    更新日期:2010-05-01 00:00:00

  • A simplified insertion technique for tracheobronchial silicone stents.

    abstract::In many patients with central airway obstruction due to extrinsic compression or malacia, insertion of tracheobronchial stents can provide effective and permanent relief. Of the various types of prostheses described, the silicone Dumon-Artemis stents (Medicore, Brussels, Belgium) are probably the most efficient. The u...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.106.2.520

    authors: Noppen M,Dhondt E,Meysman M,Monsieur I,Gepts E,Vincken WG

    更新日期:1994-08-01 00:00:00

  • Transient superior vena cava syndrome due to propylthiouracil therapy in intrathoracic goiter.

    abstract::Intrathoracic goiter is a rare cause of superior vena cava syndrome. We present the findings in a patient in whom the syndrome was precipitated by therapy with propylthiouracil and remitted on withdrawal of the medication. The superior vena cava syndrome did not recur on medical management, suggesting that surgery is ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.79.3.356

    authors: Hershey CO,McVeigh RC,Miller RP

    更新日期:1981-03-01 00:00:00

  • Liposarcoma of the posterior mediastinum in a child.

    abstract::Liposarcoma is rare in children and rarely occurs in the posterior mediastinum in any age group. A massive intrathoracic tumor in a 17-year-old young man was a diagnostic dilemma; preoperative radiographic evaluation and biopsy led us to believe it was a teratoma. At operation, a poorly differentiated myxoid liposarco...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.106.4.1288

    authors: Mikkilineni RS,Bhat S,Cheng AW,Prevosti LG

    更新日期:1994-10-01 00:00:00

  • CA-125 in Disease Progression and Treatment of Lymphangioleiomyomatosis.

    abstract:BACKGROUND:Lymphangioleiomyomatosis (LAM) is a destructive lung disease of women caused by proliferation of neoplastic-like LAM cells, with mutations in the TSC1/2 tumor suppressor genes. Based on case reports, levels of cancer antigen 125 (CA-125), an ovarian cancer biomarker, can be elevated in patients with LAM. We ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1016/j.chest.2017.05.018

    authors: Glasgow CG,Pacheco-Rodriguez G,Steagall WK,Haughey ME,Julien-Williams PA,Stylianou MP,Gochuico BR,Moss J

    更新日期:2018-02-01 00:00:00

  • Tuberculous pneumonia with the syndrome of inappropriate secretion of antidiuretic hormone: cause of the adult respiratory distress syndrome.

    abstract::Bilateral tuberculous pneumonia with the syndrome of inappropriate secretion of antidiuretic hormone was the cause of the adult respiratory distress syndrome in an elderly patient. Early recognition and prompt therapy enabled the patient to make a complete recovery without the necessity for mechanical ventilation. Wit...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.72.5.678

    authors: Sahn SA,Skeff KM

    更新日期:1977-11-01 00:00:00