Increased proportions of peripheral blood gamma delta T cells in patients with pulmonary tuberculosis.

abstract：BACKGROUND:Obesity hypoventilation syndrome (OHS) conventionally includes awake hypercapnia, but an isolated raised bicarbonate, even in the absence of awake hypercapnia, may represent evidence of "early" OHS. We investigated whether such individuals exhibit certain features characteristic of established OHS. METHODS:...

journal_title：Chest

authors： Manuel ARG,Hart N,Stradling JR

更新日期：2015-02-01 00:00:00

abstract：:Systemic air embolism is a rare but potentially fatal complication of percutaneous transthoracic needle biopsy of the lung. Coronary air embolism can result in myocardial infarction, cardiac arrest, or dysrhythmias. We present the first case of cardiac arrest and myocardial infarction confirmed by ECG and cardiac enzy...

journal_title：Chest

authors： Mokhlesi B,Ansaarie I,Bader M,Tareen M,Boatman J

更新日期：2002-03-01 00:00:00

abstract：:The clinical spectrum of mitochondrial diseases has expanded dramatically in the last decade. Abnormalities of mitochondrial function are now thought to participate in a number of common adult diseases, ranging from exercise intolerance to aging. This review outlines the common presentations of mitochondrial disease i...

journal_title：Chest

authors： Clay AS,Behnia M,Brown KK

更新日期：2001-08-01 00:00:00

abstract：:Disappointing results of surgery and postoperative adjuvant chemotherapy or chemoradiotherapy in stage IIIA (N2) lung cancer have led to a number of phase II trials of induction (neoadjuvant) chemotherapy given prior to surgery. Preliminary results of 2 such studies indicate that mitomycin, vinca alkaloid, and platinu...

journal_title：Chest

authors： Ginsberg RJ

更新日期：1993-04-01 00:00:00

abstract：STUDY OBJECTIVE:Cysteinyl leukotrienes are important proinflammatory mediators in the pathogenesis of asthma. Since bronchial hyperresponsiveness is a noninvasive surrogate marker of asthmatic airway inflammation, we evaluated the bronchoprotection afforded by leukotriene receptor antagonists (LTRAs). DESIGN:Systemati...

journal_title：Chest

authors： Currie GP,Lipworth BJ

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The study documented the emergence of new forms of resistant bacilli (totally drug-resistant [TDR] or super extensively drug-resistant [XDR] tuberculosis [TB] strains) among patients with multidrug-resistant TB (MDR-TB). METHODS:Susceptibility testing against first- and second-line drugs was performed on is...

journal_title：Chest

authors： Velayati AA,Masjedi MR,Farnia P,Tabarsi P,Ghanavi J,ZiaZarifi AH,Hoffner SE

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Disease progression in COPD is associated with a decline in exercise performance over time. We assessed whether tiotropium might mitigate this by determining its effect on treadmill endurance time (ET) over 2 years. METHODS:This was a randomized, double-blind, placebo-controlled trial of tiotropium, 18 μg d...

journal_title：Chest

authors： Cooper CB,Celli BR,Jardim JR,Wise RA,Legg D,Guo J,Kesten S

更新日期：2013-08-01 00:00:00

abstract：:This study addresses the hypothesis that patients with obstructive sleep apnea, who exhibit recurrent episodes of oxygen desaturation at night, have higher hematocrit levels than nonapneic control subjects. We prospectively studied 624 patients referred to the sleep disorders center at St. Michael's Hospital because o...

journal_title：Chest

authors： Hoffstein V,Herridge M,Mateika S,Redline S,Strohl KP

更新日期：1994-09-01 00:00:00

abstract：:In this investigation, we examined changes in exfoliated tracheobronchial cells in sputum in 46 individuals (mean age = 49.2 years; mean packyears = 48.7) who discontinued smoking and 37 individuals (mean age = 54.9 years; mean packyears = 65.2) who continued to smoke over a 12-month period after participation in the ...

journal_title：Chest

authors： Swan GE,Hodgkin JE,Roby T,Mittman C,Jacobo N,Peters J

更新日期：1992-03-01 00:00:00

abstract：:Colonization of the lower respiratory tract by enteric Gram-negative bacilli (EGNB) has been a frequent finding in patients with long-term tracheostomies; however, the association of hospitalization and certain features of serious illness with this phenomenon has not been clearly established. Because such factors can ...

journal_title：Chest

authors： Niederman MS,Ferranti RD,Zeigler A,Merrill WW,Reynolds HY

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Epidemiologic investigations of acute lung injury (ALI) and ARDS have focused on mechanically ventilated patients in ICUs, and have reported high mortality rates. We sought to determine the incidence and lethality of these syndromes in the respiratory isolation areas of general wards, a non-ICU setting that ...

journal_title：Chest

authors： Quartin AA,Campos MA,Maldonado DA,Ashkin D,Cely CM,Schein RMH

更新日期：2009-02-01 00:00:00

abstract：:Nineteen patients were treated at the Los Angeles County Harbor/UCLA Medical Center between 1971 and 1986 for tuberculosis of the spine. Fourteen were immigrants, a high-risk group. A high index of suspicion is required for Pott's disease, which occurs in fewer than 1 percent of patients with tuberculosis, often prese...

journal_title：Chest

authors： Omari B,Robertson JM,Nelson RJ,Chiu LC

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Prolonged mechanical ventilation (MV) is associated with high morbidity, mortality, and cost. However, few and limited data are available on the prediction of duration of MV. We conducted an observational cohort study to seek predictive criteria. METHODS:The study was performed in a surgical ICU (SICU) in a...

journal_title：Chest

authors： Troché G,Moine P

更新日期：1997-09-01 00:00:00

abstract：:COPD and OSA are both highly prevalent, which implies that both disorders occurring together (overlap syndrome) is likely to be common based on chance association alone. However, different clinical COPD phenotypes influence the likelihood of coexisting OSA in that the increased lung volumes and low BMI associated with...

journal_title：Chest

authors： McNicholas WT

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Portable monitoring is a convenient means for diagnosing sleep apnea. However, data on whether one night of monitoring is sufficiently precise for the diagnosis of sleep apnea are limited. RESEARCH QUESTION:The current study sought to determine the variability and misclassification in disease severity over ...

journal_title：Chest

authors： Punjabi NM,Patil S,Crainiceanu C,Aurora RN

更新日期：2020-07-01 00:00:00

abstract：:The narcotic antagonists naloxone and naltrexone were used as respiratory stimulants in two patients failing traditional medical therapy for COPD. Both patients demonstrated improvement while receiving the drugs, but developed respiratory failure when they were discontinued abruptly. In selected patients with COPD, na...

journal_title：Chest

authors： Reents SB,Beck CA Jr

更新日期：1988-01-01 00:00:00

abstract：STUDY OBJECTIVE:The primary objective of this study was to test whether an elevated systolic pulmonary artery (PA) pressure or an elevated pulmonary dead space fraction (Vd/Vt) in early acute lung injury (ALI) is associated with poor clinical outcomes in the era of lung-protective ventilation. DESIGN:Prospective obser...

journal_title：Chest

authors： Cepkova M,Kapur V,Ren X,Quinn T,Zhuo H,Foster E,Liu KD,Matthay MA

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:There is a growing understanding of the prevalence and impact of psychological disorders on COPD. However, the role of these disorders in early readmission is unclear. METHODS:We analyzed data from 5% fee-for-service Medicare beneficiaries diagnosed with COPD (International Classification of Diseases, Ninth...

journal_title：Chest

authors： Singh G,Zhang W,Kuo YF,Sharma G

更新日期：2016-04-01 00:00:00

abstract：:A 26-year-old man developed coccidioidomycosis which resulted in myocarditis associated with congestive heart failure. A pericardial effusion developed and progressed to constrictive pericarditis. A pericardiectomy was performed and revealed that the pericarditis was due to Coccidioides immitis. The patient was subseq...

journal_title：Chest

authors： Schwartz EL,Waldmann EB,Payne RM,Goldfarb D,Kinard SA

更新日期：1976-11-01 00:00:00

abstract：:Histochemical quantification of goblet cells and measurements of the epithelial thickness were made in the trachea of male and female rats exposed to fresh whole tobacco smoke for 30 consecutive days. Exposure to tobacco smoke resulted in an increase in the total goblet cell count in both sexes, with the female rats d...

journal_title：Chest

authors： Hayashi M,Sornberger GC,Huber GL

更新日期：1978-04-01 00:00:00

abstract：:Increased (more positive) end-expiratory and decreased (more negative) end-inspiratory values for intrapleural pressure (PpI) invariably accompany acute bronchoconstriction. We hypothesize that both the increase in vital capacity (VC) and the decrease in residual volume (RV) observed after dilation of the central airw...

journal_title：Chest

authors： Lavietes MH,Taylor DW

更新日期：1979-10-01 00:00:00

abstract：STUDY OBJECTIVES:Previous studies have reported that magnesium (Mg) deficiency is associated with coronary spasm. However, little is known about the preventive effect of Mg on coronary spasm. The present study investigated whether Mg prevents coronary spasm in patients with vasospastic angina (VSA). DESIGN:Effectivene...

journal_title：Chest

authors： Teragawa H,Kato M,Yamagata T,Matsuura H,Kajiyama G

更新日期：2000-12-01 00:00:00

abstract：:Activated charcoal usually provides effective and safe treatment for drug overdose. We describe a patient who developed bronchiolitis obliterans and respiratory failure following aspiration of activated charcoal. This patient had a markedly reduced vital capacity with roentgenographic evidence of airtrapping. Chest ro...

journal_title：Chest

authors： Elliott CG,Colby TV,Kelly TM,Hicks HG

更新日期：1989-09-01 00:00:00

abstract：:Paclitaxel, the first of the taxanes, has exhibited unique and encouraging single-agent activity in the treatment of non-small cell lung cancer (NSCLC). Yet, with single-agent response rates approaching 25%, it was logical to examine the impact of paclitaxel in combination chemotherapy regimens. In trials evaluating t...

journal_title：Chest

authors： Belani CP

更新日期：2000-04-01 00:00:00

abstract：STUDY OBJECTIVES:This multicenter study was undertaken to characterize the population of ventilator-dependent patients admitted to long-term care hospitals (LTCHs) with weaning programs, and to report treatments, complications, weaning outcome, discharge disposition, and survival in these patients. DESIGN:Observationa...

journal_title：Chest

authors： Scheinhorn DJ,Hassenpflug MS,Votto JJ,Chao DC,Epstein SK,Doig GS,Knight EB,Petrak RA,Ventilation Outcomes Study Group.

更新日期：2007-01-01 00:00:00

abstract：UNLABELLED:Protected specimen brush (PSB) is considered to be one of the standard methods for the diagnosis of ventilator-associated pneumonia, but to our knowledge, intraindividual variability in results has not been reported previously. PURPOSE:To compare the results of two PSB performed in the same subsegment on pa...

journal_title：Chest

authors： Timsit JF,Misset B,Francoual S,Goldstein FW,Vaury P,Carlet J

更新日期：1993-07-01 00:00:00

abstract：:We retrospectively studied the acute toxicity of corticosteroid therapy in 23 episodes of PCP occurring in the setting of AIDS and determined the incidence of HIV-related complications following these and 16 other contemporaneous episodes of AIDS-related PCP treated with antimicrobials alone. The mean duration of cort...

journal_title：Chest

authors： Lambertus MW,Goetz MB,Murthy AR,Mathisen GE

更新日期：1990-07-01 00:00:00

abstract：:To evaluate the effect of inhaled diuretics, furosemide and amiloride, on cough induced by acid inhalation challenge in asthmatic children, a double-blind, randomized, placebo-controlled study was conducted. On separate days, 12 asthmatic children (10.3 +/- 0.7 [SEM] years) underwent acetic acid (AD) inhalation challe...

journal_title：Chest

authors： Mochizuki H,Shimizu T,Morikawa A,Kuroume T

更新日期：1995-02-01 00:00:00

abstract：:The chest radiograph of a woman with acute asthma showed signs of obstructive emphysema of the left lung. Fiberoptic bronchoscopy excluded obstruction of a large bronchus. The signs disappeared after antiasthmatic treatment, suggesting that they were caused by airway closure. In usual asthma, airway closure affects bo...

journal_title：Chest

authors： DiFrancia M,Barbier D,Orehek J

更新日期：1993-12-01 00:00:00

abstract：:Combination chemotherapy has dramatically improved the prognosis of patients with intermediate and high grade histologic subtypes of non-Hodgkin's lymphomas. Treatment-related complications, however, are considerable, and a common problem encountered is respiratory distress or respiratory insufficiency. Usually these ...

journal_title：Chest

authors： Glenn LD,Armitage JO,Goldsmith JC,Sorensen S,Howe D,Weisenberger DD

更新日期：1988-09-01 00:00:00