An analysis of in vitro T cell responsiveness in nontuberculous mycobacterial infection.

abstract：:To assess the value of bronchoalveolar lavage (BAL) for diagnosis, understanding, and treatment of amiodarone-associated pneumonitis, we examined the results of BAL total and differential cell counts and phenotyping of lymphocytes in 22 patients with this lung disorder and in 33 normal subjects. Overall, the total cel...

journal_title：Chest

authors： Akoun GM,Cadranel JL,Blanchette G,Milleron BJ,Mayaud CM

更新日期：1991-05-01 00:00:00

abstract：:The self-expandable stainless steel stents (Gianturco, William Cook, Bjaeverskov, Denmark) used extensively in biliary ducts and the vascular system have recently been modified for use in the tracheobronchial tree. Between March 1991 and September 1992, six patients with unresectable tracheobronchial and mediastinal d...

journal_title：Chest

authors： Zannini P,Melloni G,Chiesa G,Carretta A

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Participant retention is a major challenge in clinical research, especially in studies with multiple, longitudinal research assessments. Despite the importance of retention methods, there is little empirical research on how cohort retention efforts are perceived by study participants. RESEARCH QUESTION:To e...

journal_title：Chest

authors： Eakin MN,Eckmann T,Dinglas VD,Akinremi AA,Hosey M,Hopkins RO,Needham DM

更新日期：2020-08-01 00:00:00

abstract：:Pathologic obstruction of the proximal lumen and secondary atrophy of the media of the peripheral small pulmonary arteries were absolute operative contraindications in cases of VSD and/or PDA with severe pulmonary hypertension. Such patients who were operated on died with no decrease in pulmonary arterial pressure. Th...

journal_title：Chest

authors： Yamaki S,Mohri H,Haneda K,Endo M,Akimoto H

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:DVT is common among critically ill patients. A rapid and accurate diagnosis is essential for patient care. We assessed the accuracy and timeliness of intensivist-performed compression ultrasonography studies (IP-CUS) for proximal lower extremity DVT (PLEDVT) by comparing results with the formal vascular stud...

journal_title：Chest

authors： Kory PD,Pellecchia CM,Shiloh AL,Mayo PH,DiBello C,Koenig S

更新日期：2011-03-01 00:00:00

abstract：STUDY OBJECTIVES:Vascular endothelial growth factor (VEGF) signaling may be required for maintenance of the alveolar structures, and alveolar septal cell apoptosis could contribute to the pathogenesis of COPD presenting emphysematous changes; however, the common mutation at position 936 in the 3' untranslated region of...

journal_title：Chest

authors： Sakao S,Tatsumi K,Hashimoto T,Igari H,Shino Y,Shirasawa H,Kuriyama T

更新日期：2003-07-01 00:00:00

abstract：:OSA is associated with significant adverse outcomes with far-reaching health-care implications. OSA is much more common and severe in patients with Down syndrome (DS) than in the general population, yet there is a striking lack of literature in this area. In this review article, we have summarized the current state of...

journal_title：Chest

authors： Lal C,White DR,Joseph JE,van Bakergem K,LaRosa A

更新日期：2015-02-01 00:00:00

abstract：:Morbid obesity is often associated with severe respiratory insufficiency, commonly known as the pickwickian syndrome. This can be divided into the following two primary breathing disorders which can affect patients alone or in combination: the obstructive sleep apnea syndrome (SAS); and the obesity-hypoventilation syn...

journal_title：Chest

authors： Sugerman HJ,Fairman RP,Baron PL,Kwentus JA

更新日期：1986-07-01 00:00:00

abstract：:Elevated endorphin levels in patients with COPD may act to diminish the sensation of dyspnea. Exogenous opioids decrease exertional dyspnea and increase exercise capacity in COPD patients. The purpose of this study was to determine the effects of endogenous opioids on the exercise capacity and control of breathing in ...

journal_title：Chest

authors： Kirsch JL,Muro JR,Stansbury DW,Fischer CE,Monfore R,Light RW

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Clinical resolution of ventilator-associated pneumonia (VAP) determines the duration of treatment and mechanical ventilation. The aim of this study was to evaluate the influence of organisms and their susceptibility to treatment on outcomes. METHODS:Prospective observational study in three teaching ICUs. Si...

journal_title：Chest

authors： Vidaur L,Planas K,Sierra R,Dimopoulos G,Ramirez A,Lisboa T,Rello J

更新日期：2008-03-01 00:00:00

abstract：:A six-month-old girl with an aberrant systemic arterial supply from the descending thoracic aorta to the left lower lobe had congestive heart failure. Although the pulmonary parenchyma was normal, there was an absence of normal pulmonary arterial supply to the left lower lobe. Main pulmonary arterial and aortic cinean...

journal_title：Chest

authors： Yabek SM,Burstein J,Berman W Jr,Dillon T

更新日期：1981-11-01 00:00:00

abstract：:alpha 1-Antitrypsin (alpha 1-AT) accumulates in the rough endoplasmic reticulum through a mechanism of polymerization. Polymerization is favored by the incorrect tertiary structure of the alpha 1-AT caused by a point mutation at position 342 of the protein. Accumulation of alpha 1-AT in the liver cells (and in hepatoc...

journal_title：Chest

authors： Massi G

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:We recently showed that administration of the combination of the noradrenergic drug atomoxetine plus the antimuscarinic oxybutynin (ato-oxy) prior to sleep greatly reduced OSA severity, likely by increasing upper airway dilator muscle activity during sleep. In patients with OSA who performed the ato-oxy tria...

journal_title：Chest

authors： Taranto-Montemurro L,Messineo L,Azarbarzin A,Vena D,Hess LB,Calianese NA,White DP,Wellman A,Sands SA

更新日期：2020-06-01 00:00:00

abstract：:This study demonstrates that when the heart is markedly displaced posteriorly to the left, or perhaps to the right, the posterior approach may make echocardiographic evaluation possible. Thus, in a patient with congenital unilateral absence of the left pulmonary artery, with marked displacement of the heart posteriorl...

journal_title：Chest

authors： Borgeson E,Vogel JH

更新日期：1980-01-01 00:00:00

abstract：:In this pilot study, murine monoclonal anti-TNF antibody (2 mg/kg) was administered to ten patients within 24 h of septic shock which persisted after initial resuscitation with intravenous fluids and adrenergic agents. This treatment resulted in a reduction in heart rate (from 122 +/- 10 to 113 +/- 10 beats per minute...

journal_title：Chest

authors： Vincent JL,Bakker J,Marécaux G,Schandene L,Kahn RJ,Dupont E

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVES:Studies documenting the increased incidence of exercise-induced bronchospasm (EIB) in figure skaters have employed a method that incorporates on-ice exercise with rink-side spirometry. The literature suggests that bronchial provocation challenge testing is better than exercise testing for identifying EIB. To...

journal_title：Chest

authors： Mannix ET,Manfredi F,Farber MO

更新日期：1999-03-01 00:00:00

abstract：:This study compared the bronchodilator effect in experimental canine asthma of dyphylline administered by aerosol and intravenous routes in doses producing equivalent concentrations of the drug in the plasma. Pulmonary resistance (RL) was calculated from simultaneous measurements of pressure and flow during fixed-volu...

journal_title：Chest

authors： Hirshman CA,Lawyer C,Downes H,Farbood A,Rodgers R,Gerber N

更新日期：1981-04-01 00:00:00

abstract：:Forty-three consecutive patients requiring endotracheal intubation in an emergency room were studied prospectively to define the complications associated with intubation and the survival of these patients, and to evaluate emergency room policies. The indications for intubation were acute respiratory failure (ARF) in 2...

journal_title：Chest

authors： Taryle DA,Chandler JE,Good JT Jr,Potts DE,Sahn SA

更新日期：1979-05-01 00:00:00

abstract：:A 32-year-old man who presented with symptoms suggesting empyema was found at thoracotomy to have infarction of an extralobar pulmonary sequestration. He was completely relieved by excision of the sequestration after securing the systemic vascular pedicle which had undergone torsion. Recognition of the anomalous blood...

journal_title：Chest

authors： Maull KI,McElvein RB

更新日期：1975-07-01 00:00:00

abstract：:The role of infection in exacerbations of COPD remains controversial and incompletely understood. Although some investigators believe that bacteria are not important for patients with exacerbation, we disagree and believe that patients with at least two of the three cardinal symptoms of exacerbation should receive ant...

journal_title：Chest

authors： Murphy TF,Sethi S,Niederman MS

更新日期：2000-07-01 00:00:00

abstract：:We performed autonomic function testing in 68 patients, 34 with diabetes mellitus (group A) and 34 without (group B), at 72 h after a first acute myocardial infarction (MI) to determine the prevalence of autonomic dysfunction in these patients. Heart rate (HR) variation during 6 breaths/min obtained from mean of longe...

journal_title：Chest

authors： Bhatnagar SK,Al-Yusuf AR,Al-Asfoor AR

更新日期：1987-11-01 00:00:00

abstract：:To evaluate bronchoalveolar lavage (BAL) findings in patients infected with human immunodeficiency virus (HIV), 39 patients seropositive for the virus but with no history of opportunistic infection were studied. Opportunistic organisms such as Pneumocystis carinii were not found in any of the 35 BAL fluids sent for sp...

journal_title：Chest

authors： Johnson JE,Anders GT,Hawkes CE,LaHatte LJ,Blanton HM

更新日期：1990-05-01 00:00:00

abstract：:The levels of soluble IL-2R were measured in pleural fluid from patients with tuberculosis pleurisy. There were significantly elevated soluble IL-2R values in tuberculous pleural fluid as compared with pleural fluid of nontuberculous etiology including malignant, bacterial and transudative pleural effusions. In patien...

journal_title：Chest

authors： Ito M,Kojiro N,Shirasaka T,Moriwaki Y,Tachibana I,Kokubu T

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Clinical practice guidelines recommend enteral over parenteral nutrition in critical illness and do not recommend early initiation. Few data are available on parenteral nutrition use or timing of initiation in the ICU or how this use may have changed over time. METHODS:We used the Project IMPACT database to...

journal_title：Chest

authors： Gershengorn HB,Kahn JM,Wunsch H

更新日期：2014-03-01 00:00:00

abstract：:Because T-piece breathing may impair oxygenation, the best airway pressure from which to extubate ventilated patients is controversial. We compared the effects of extubation after 1 h of either CPAP 5 and T-piece/ZEEP. Once weaned from mechanical ventilation and breathing spontaneously, 106 patients were randomized to...

journal_title：Chest

authors： Jones DP,Byrne P,Morgan C,Fraser I,Hyland R

更新日期：1991-12-01 00:00:00

abstract：:Hydrochlorothiazide (HCTZ)-induced pulmonary disease has been described as either an allergic interstitial pneumonitis or a cause of noncardiogenic pulmonary edema. The mechanism of this rare life-threatening side effect is largely unknown. Many patients show peripheral leukopenia and extensive immunologic studies rev...

journal_title：Chest

authors： Darwish OS,Criley J

更新日期：2011-01-01 00:00:00

abstract：STUDY OBJECTIVES:To determine whether the quantitative evaluation of hemomediastinum using transesophageal echocardiography (TEE) is predictive of the presence of a traumatic disruption of the thoracic aorta (TDA) or its branches in patients who have sustained severe blunt chest trauma. DESIGN:Retrospective study. SE...

journal_title：Chest

authors： Vignon P,Rambaud G,François B,Preux PM,Lang RM,Gastinne H

更新日期：1998-06-01 00:00:00

abstract：:Because of its greater ease and rapidity of insertion, the percutaneous intraaortic balloon in many institutions has become the primary method for implementing counterpulsation. We report the results and complications of 113 attempted procedures in a variety of clinical settings. We had a high (93.8 percent) insertion...

journal_title：Chest

authors： Hauser AM,Gordon S,Gangadharan V,Ramos RG,Westveer DC,Garg AK,Timmis GC

更新日期：1982-10-01 00:00:00

abstract：STUDY OBJECTIVES:To determine whether the nuclear accumulation of p53 in patients with early bronchial neoplasia represents an altered susceptibility for the development of lung cancer. PATIENTS AND MEASUREMENTS:We evaluated the percentage of cells accumulating nuclear p53 immunohistochemically in squamous cell carcin...

journal_title：Chest

authors： Piyathilake CJ,Frost AR,Manne U,Weiss H,Heimburger DC,Grizzle WE

更新日期：2003-01-01 00:00:00

abstract：STUDY OBJECTIVES:We investigated the role of two leukotriene B4 (LTB4) receptors, BLT1 and peroxisome proliferator-activated receptor (PPAR)-alpha, in conferring the susceptibility to develop COPD in smokers. Proinflammatory LTB4 activities are mediated by BLT1, while the inactivation of LTB4 is promoted by PPARalpha. ...

journal_title：Chest

authors： Marian E,Baraldo S,Visentin A,Papi A,Saetta M,Fabbri LM,Maestrelli P

更新日期：2006-06-01 00:00:00