Hydrochlorothiazide-induced noncardiogenic pulmonary edema: BAL fluid analysis.

Abstract:

:Hydrochlorothiazide (HCTZ)-induced pulmonary disease has been described as either an allergic interstitial pneumonitis or a cause of noncardiogenic pulmonary edema. The mechanism of this rare life-threatening side effect is largely unknown. Many patients show peripheral leukopenia and extensive immunologic studies reveal decreased levels of serum immunoglobulins. However, evaluation of the peripheral blood may not reflect local lung changes. Literature reports of bronchoalveolar differentials on such patients are scarce. Bronchoscopy was performed on our patient, and the lavage revealed a significant percentage of neutrophils (70%) and no eosinophils.

journal_name

Chest

journal_title

Chest

authors

Darwish OS,Criley J

doi

10.1378/chest.10-0944

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

193-4

issue

1

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(11)60033-0

journal_volume

139

pub_type

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