Nonsurgical treatment of Histoplasma endocarditis involving a bioprosthetic valve.

Abstract:

:Endocardial involvement associated with disseminated histoplasmosis has been infrequently documented, especially among patients with prosthetic valves. The therapeutic approach to these patients is also not yet clearly defined. A 54-year-old man with prosthetic valve endocarditis due to histoplasmosis was successfully treated with amphotericin B. A review of the literature suggests that the optimal form of therapy is likely a combination of surgical replacement of the involved valve and high dose amphotericin B. Successful therapy with amphotericin B alone may, however, be achieved if surgery is not a viable option.

journal_name

Chest

journal_title

Chest

authors

Kanawaty DS,Stalker MJ,Munt PW

doi

10.1378/chest.99.1.253

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

253-6

issue

1

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)30287-2

journal_volume

99

pub_type

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