The use of learning resource centers in the teaching of pulmonary medicine.

abstract：STUDY OBJECTIVES:We investigated the role of two leukotriene B4 (LTB4) receptors, BLT1 and peroxisome proliferator-activated receptor (PPAR)-alpha, in conferring the susceptibility to develop COPD in smokers. Proinflammatory LTB4 activities are mediated by BLT1, while the inactivation of LTB4 is promoted by PPARalpha. ...

journal_title：Chest

authors： Marian E,Baraldo S,Visentin A,Papi A,Saetta M,Fabbri LM,Maestrelli P

更新日期：2006-06-01 00:00:00

abstract：:POC testing provides an opportunity for clinicians and laboratorians to work together to consider how best to serve the patients within an individual institution. Each health system has unique characteristics relative to patient population, as well as a unique laboratory structure. If physicians, nurses, laboratorians...

journal_title：Chest

authors： Kost GJ,Ehrmeyer SS,Chernow B,Winkelman JW,Zaloga GP,Dellinger RP,Shirey T

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Interferon-γ release assays (IGRAs) have been incorporated into several national guidelines for latent TB infection (LTBI) diagnosis. However, their optimal application is still controversial and evolving. The aim of this study is to evaluate the performance of confirmatory IGRAs in addition to tuberculin sk...

journal_title：Chest

authors： Song S,Jeon D,Kim JW,Kim YD,Kim SP,Cho JS,Lee SE,Cho WH,Park HK,Kim YS,Lee MK,Lee JH

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Among patients hospitalized for community-acquired pneumonia (CAP), the risk factors for short-term hospital readmission after discharge are unknown. METHODS:We conducted a prospective observational study of 1,117 patients who had been discharged alive after hospitalization for CAP. We collected variables a...

journal_title：Chest

authors： Capelastegui A,España Yandiola PP,Quintana JM,Bilbao A,Diez R,Pascual S,Pulido E,Egurrola M

更新日期：2009-10-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the effectiveness of treatment with corticosteroids in patients with COPD. METHODS:In this study, we investigated the effect of a 2-year treatment with corticosteroids on clinical symptoms and the decline of lung function in 58 nonallergic patients with COPD. Subjects were treated in a dou...

journal_title：Chest

authors： Renkema TE,Schouten JP,Koëter GH,Postma DS

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Lung cancer screening, despite its proven mortality benefit, remains vastly underutilized. Previous studies examined knowledge, attitudes, and beliefs to better understand the reasons underlying the low screening rates. These investigations may have limited generalizability because of traditional participant...

journal_title：Chest

authors： Monu J,Triplette M,Wood DE,Wolff EM,Lavallee DC,Flum DR,Farjah F

更新日期：2020-07-01 00:00:00

abstract：:The factors that influence decision making among surgeons are not well understood. We evaluated how tumor stage in patients subjected to potentially curative surgery for lung cancer affects the self-reported follow-up strategies employed by practicing surgeons. Hypothetical patient profiles and a detailed questionnair...

journal_title：Chest

authors： Johnson FE,Naunheim KS,Coplin MA,Virgo KS

更新日期：1997-01-01 00:00:00

abstract：:The role of thoracic radiation therapy in the management of limited-stage small cell lung cancer (SCLC) is reviewed. Although chest irradiation has been used to treat SCLC for over four decades, its standard role in the management of limited-stage disease was established only during the last decade. Multiple prospecti...

journal_title：Chest

authors： Kumar P

更新日期：1997-10-01 00:00:00

abstract：:A 48-year-old man with unipolar depression and a psychosexual problem concerning his body image was injecting his scrotum repeatedly with olive oil to increase the size of his genitals. He developed respiratory failure following accidental intravenous injection of olive oil and was found to have lipogranulomatous lesi...

journal_title：Chest

authors： Bhagat R,Holmes IH,Kulaga A,Murphy F,Cockcroft DW

更新日期：1995-03-01 00:00:00

abstract：:Thirty-eight high-risk patients (forced expiratory volume in one second [FEV1] less than 2.0L or maximum voluntary ventilation [MVV] less than 50 per cent of predicted) were observed for a minimum of one year after pneumonectomy for carcinoma of the lung. Operability was assessed by calculating a predicted postoperati...

journal_title：Chest

authors： Boysen PG,Harris JO,Block AJ,Olsen GN

更新日期：1981-08-01 00:00:00

abstract：:Thirty-three patients with T3,N2,M0 or T4,N2,M0, non-small-cell lung cancer (NSCLC) took part in a phase 2 study in an attempt to evaluate the feasability of neoadjuvant chemotherapy followed by surgery and thoracic radiotherapy. Chemotherapy consisted of daily administration of the following treatment: etoposide, 100...

journal_title：Chest

authors： Pujol JL,Hayot M,Rouanet P,Le Chevalier T,Michel FB

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Failure to reliably diagnose ARDS may be a major driver of negative clinical trials and underrecognition and treatment in clinical practice. We sought to examine the interobserver reliability of the Berlin ARDS definition and examine strategies for improving the reliability of ARDS diagnosis. METHODS:Two hu...

journal_title：Chest

authors： Sjoding MW,Hofer TP,Co I,Courey A,Cooke CR,Iwashyna TJ

更新日期：2018-02-01 00:00:00

abstract：:We studied eight patients with miliary tuberculosis (TB). In all instances, tuberculomatous lesions were demonstrated in the aspirated bone marrow. We conclude that the bone marrow aspiration has great value in diagnosing miliary TB because it provides sufficient material to permit examination of serial sections as ne...

journal_title：Chest

authors： Kinoshita M,Ichikawa Y,Koga H,Sumita S,Oizumi K

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:In patients who have experienced acute myocardial infarction (MI), primary percutaneous coronary intervention (PCI) has been shown to be of benefit in terms of clinical outcomes. However, the value of performing routine PCI in patients with early MI (ie, an MI occurring > 12 h to < or = 7 days before patient...

journal_title：Chest

authors： Yip HK,Wu CJ,Yang CH,Chang HW,Chen SM,Hung WC,Hang CL

更新日期：2004-07-01 00:00:00

abstract：:We evaluated two patients with systemic cholesterol embolization (SCE) associated with the development of pleural effusions. These two patients had evidence of atherosclerosis and presented with livedo reticularis, renal insufficiency, and gangrenous cutaneous changes as manifestations of their SCE. In both cases, clo...

journal_title：Chest

authors： Kollef MH,McCormack MT,Kristo DA,Reddy VV

更新日期：1993-03-01 00:00:00

abstract：:This report describes a 25-year follow-up of angiographically proven bilateral functioning Vineberg grafts. This represents the longest angiographic follow-up found in the literature. The relevance of these grafts in present-day revascularization procedures is discussed. ...

journal_title：Chest

authors： Hughes MM

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Inhaled magnesium (Mg) seemed to have a mild protective (nonbronchodilator) effect against histamine and methacholine. Inhaled sodium metabisulfite (MBS) causes bronchoconstriction in asthma through indirect mechanisms that involve sensory nerve stimulation, and it is extensively used to study airway hyperre...

journal_title：Chest

authors： Nannini LJ Jr,Hofer D

更新日期：1997-04-01 00:00:00

abstract：:We wanted to determine the efficacy of dobutamine infusions and Prbc transfusions on splanchnic tissue oxygen utilization by measuring gastric pHi. Physiologic parameters and pHi measurements via the use of a gastric tonometer were obtained in 21 septic patients before and after the administration of a dobutamine infu...

journal_title：Chest

authors： Silverman HJ,Tuma P

更新日期：1992-07-01 00:00:00

abstract：:A saccular aneurysm arising from the descending thoracic aorta was identified ultrasonically in a 60-year-old man with a subsequent pathologic diagnosis of a Listeria monocytogenes mycotic aneurysm. A cross-sectional scanning technique, which permitted visualization of the descending thoracic aorta in long axis, demon...

journal_title：Chest

authors： Come PC,Sacks B,Vine H,McArdle C,Koretsky S,Weintraub R

更新日期：1981-04-01 00:00:00

abstract：:We studied hypoxic and hypercapnic ventilatory drives in 22 eucapnic obese subjects (14 female and eight male subjects) referred for weight reduction therapy and 23 normal subjects (eight female and 15 male subjects). In the female subjects, both occlusion pressure, currently used as an indicator of ventilatory drive,...

journal_title：Chest

authors： Kunitomo F,Kimura H,Tatsumi K,Kuriyama T,Watanabe S,Honda Y

更新日期：1988-05-01 00:00:00

abstract：PURPOSE:The purpose of this study was to compare the pressure required to abolish apneas as predicted from a previously derived algorithm (Ppred) with the true effective pressure (Peff) determined during a continuous positive airway pressure (CPAP) titration study. SETTING:Sleep clinic of a university hospital. METHO...

journal_title：Chest

authors： Oliver Z,Hoffstein V

更新日期：2000-04-01 00:00:00

abstract：:The mechanisms leading to rapid changes in arterial blood gas values soon after exercise ends have not been well established. To further study these phenomena, we exercised seven normal male volunteers to exhaustion on a cycle ergometer with a 25-W/min ramped protocol measuring arterial blood gas values, and breath-by...

journal_title：Chest

authors： O'Neill AV,Johnson DC

更新日期：1991-05-01 00:00:00

abstract：:The endocrinometabolic effects of the aerosol administration of beclomethasone dipropionate (100 microng four times daily) were evaluated in 20 asthmatic patients (11 corticodependent and nine noncorticodependent) during one month. In the noncorticodependent group, aerosol administration of beclomethasone had no stati...

journal_title：Chest

authors： Yernault JC,Leclercq R,Schandevyl W,Virasoro E,De Coster A,Copinschi G

更新日期：1977-06-01 00:00:00

abstract：:Patients with diffuse interstitial lung diseases (DILD) are challenging to treat. Many patients with DILD have inadequate information about the disease process, an imprecise diagnosis, unsatisfactory treatment or unacceptable side effects associated with therapy, and poorly controlled symptoms of progressive illness. ...

journal_title：Chest

authors： Reynolds HY

更新日期：1998-01-01 00:00:00

abstract：:Complications following open chest massage in patients with porcine xenografts in the mitral location have not been previously described. The authors report a case of cardiac resuscitation following mitral valve replacement with a stented porcine valve. The patient died following brief closed chest, and then, prolonge...

journal_title：Chest

authors： Wild LM,Lajos TZ,Lee AB Jr,Wright J

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVE:An overdiagnosis bias occurs with the diagnosis of a disease that does not produce signs or symptoms before the patient dies from other causes. We sought to determine whether overdiagnosis bias is a factor when screening for squamous cell carcinoma of the lung. DESIGN:Retrospective study of the Miyagi Popula...

journal_title：Chest

authors： Sato M,Saito Y,Endo C,Sakurada A,Feller-Kopman D,Ernst A,Kondo T

更新日期：2004-07-01 00:00:00

abstract：:Pulmonary torsion is very rare, and usually occurs following lung resection. We report a case of spontaneous middle lobe torsion in a patient presenting with a right pleural effusion. The condition was treated by lobectomy through a totally thoracoscopic approach. ...

journal_title：Chest

authors： Raynaud C,Lenoir S,Caliandro R,Raffenne L,Validire P,Gossot D

更新日期：2009-07-01 00:00:00

abstract：:Morbid obesity is often associated with severe respiratory insufficiency, commonly known as the pickwickian syndrome. This can be divided into the following two primary breathing disorders which can affect patients alone or in combination: the obstructive sleep apnea syndrome (SAS); and the obesity-hypoventilation syn...

journal_title：Chest

authors： Sugerman HJ,Fairman RP,Baron PL,Kwentus JA

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:Devices that reduce technical difficulty and anastigmatic time when repairing large vessels such as the thoracic aorta would be beneficial. The aim of this study was to determine if titanium vascular closure staples (3 mm) could be safely and quickly applied in the repair of large vessels such as the thoracic...

journal_title：Chest

authors： Deb S,Martin B,Sun L,Burris D,Wherry D,Pikoulis E,Rhee P

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:To describe the anatomy and neurophysiology of the cough reflex. METHODS:A review of the literature was carried out using PubMed and the ISI Web of Knowledge from 1951 to 2004. Most of the referenced studies were carried out in animals CONCLUSIONS:Studies carried out in animals provide suggestive but incon...

journal_title：Chest

authors： Canning BJ

更新日期：2006-01-01 00:00:00