Phosphodiesterase 4 inhibitors for the treatment of COPD.

abstract：INTRODUCTION:Most experimental studies of orthotopic heart and lung graft failure are complicated by an inability to eliminate the rejection-specific inflammatory mediator from the cardiopulmonary bypass. METHODS:The following model was developed in our laboratory to investigate the feasibility of performing an orthot...

journal_title：Chest

authors： Otaki M,Inoue T,Matsumoto T,Kitayama H,Oku H

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Pulmonary disease due to Mycobacterium avium complex (MAC-PD) radiographically resembles that due to tuberculosis; it preferentially affects elderly white men with predisposing pulmonary disorders (PDPD). METHODS:Twenty-nine patients with MAC-PD were identified from a community-based population, and the med...

journal_title：Chest

authors： Reich JM,Johnson RE

更新日期：1992-06-01 00:00:00

abstract：:Extrapulmonary tuberculosis refers to Mycobacterium tuberculosis involving organs other than the lungs (eg, pleura, lymph nodes, genitourinary tract, abdomen, skin, joints and bones, or meninges). In non-HIV-endemic areas, where reactivation is the predominant mechanism of tuberculosis, pleural involvement occurs in 4...

journal_title：Chest

authors： Gleason JB,Tashtoush B,Mehta J,Savage E,Martinez F,Mehta AC

更新日期：2016-10-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the incidence and clinical factors related to the persistence of infarct-associated pericardial effusion (PE) after primary angioplasty. DESIGN:Consecutive case-series analysis. SETTING:Coronary care unit in a university hospital. PATIENTS:Three hundred ninety-one consecutive patients wit...

journal_title：Chest

authors： Sugiura T,Nakamura S,Kudo Y,Okumiya T,Yamasaki F,Iwasaka T

更新日期：2005-08-01 00:00:00

abstract：:Sacrococcygeal teratoma is rarely diagnosed in adults. Pulmonary mass as the presenting clinical form of the malignant variety of this germ-cell tumor is exceptional. We report herein such a case with the noticeable peculiarity of showing the air meniscus sign on chest roentgenographic examination. ...

journal_title：Chest

authors： Roig J,Aguilar X,Maestre J,Domingo C,Morera J

更新日期：1991-08-01 00:00:00

abstract：:In two patients with acute dissection of the ascending aorta, the diagnosis was made with two-dimensional echocardiography and confirmed by aortography. The echocardiograms localized the intimal flap and false channel in both cases. Although clinical evaluation and indicated radiologic studies remain the primary modal...

journal_title：Chest

authors： Rubenson DS,Fowles RE,Miller DC,Guthaner DF,Popp RL

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Our laboratory uses pH paper rather than a blood gas analyzer to measure pleural fluid pH to decrease cost and avoid analyzer malfunction due to viscous fluids. METHODS:To compare these two methods of determining pleural fluid pH, 42 patients undergoing diagnostic or therapeutic thoracentesis had two 1-mL a...

journal_title：Chest

authors： Lesho EP,Roth BJ

更新日期：1997-11-05 00:00:00

abstract：BACKGROUND:Increased right ventricular afterload leads to left ventricular diastolic dysfunction due to ventricular interdependence. Increased right ventricular afterload is frequently present in patients with COPD. The purpose of this study was to determine whether left ventricular diastolic dysfunction could be detec...

journal_title：Chest

authors： Funk GC,Lang I,Schenk P,Valipour A,Hartl S,Burghuber OC

更新日期：2008-06-01 00:00:00

abstract：CASE PRESENTATION:A 34-year-old woman presented for evaluation of several months of a hoarse voice and dyspnea on exertion that progressed over the last 3 years. She had a clinical diagnosis of asthma that had been treated with bronchodilators and inhaled corticosteroids for a few years. She continued to use her inhale...

journal_title：Chest

authors： Jalil BA,Smith JS,El-Kersh K

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Lidocaine is used to alleviate procedural pain but paradoxically increases pain during injection. Pain perception can be modulated by non-noxious stimuli such as temperature or touch according to the gate control theory of pain. We postulated that lidocaine dripped onto the skin prior to injection would cool...

journal_title：Chest

authors： Patel BK,Wendlandt BN,Wolfe KS,Patel SB,Doman ER,Pohlman AS,Hall JB,Kress JP

更新日期：2018-10-01 00:00:00

abstract：:Cardiac dysfunction due to systemic sarcoidosis is most of ten due to severe restrictive pulmonary diseases. Although the diagnosis is frequently missed during life, direct granulomatous infiltration of the myocardium may occur with systemic sarcoidosis and, when present in the heart, is a major cause of death. To exp...

journal_title：Chest

authors： Bulkley BH,Rouleau JR,Whitaker JQ,Strauss HW,Pitt B

更新日期：1977-07-01 00:00:00

abstract：:A 62-year-old woman had had kyphoscoliosis since age 12 years. Respiratory failure developed at age 35 years following a respiratory infection. A tracheostomy was done and she required assisted ventilation using a respiratory (Bird). Many attempts at weaning her from the ventilator were unsuccessful. She has remained ...

journal_title：Chest

authors： Woolf CR

更新日期：1990-11-01 00:00:00

abstract：:Ventilation and gas exchange were studied during sleep and incremental treadmill exercise in 19 patients with severe stable COPD with the primary aim of comparing the pathophysiology of oxygen desaturation in the two conditions. A secondary aim was to determine whether exercise studies could aid in the prediction of s...

journal_title：Chest

authors： Mulloy E,McNicholas WT

更新日期：1996-02-01 00:00:00

abstract：:Platypnea-orthodeoxia is an uncommon syndrome that may occur due to the postpneumonectomy state, cirrhosis of the liver, recurrent pulmonary embolism, and intracardiac shunting. We describe a patient who was found to have a positional change in desaturation after being admitted for dehydration. Workup revealed an atri...

journal_title：Chest

authors： Acharya SS,Kartan R

更新日期：2000-09-01 00:00:00

abstract：:The systemic pressor effects of angiotensin II (ANGII) are well described, whereas relatively little is known regarding its effects on the pulmonary circulation in humans. Doppler echocardiographic measurements were performed in eight normal volunteers after a 30-min control infusion (baseline), after sequential 30 mi...

journal_title：Chest

authors： Lipworth BJ,Dagg KD

更新日期：1994-05-01 00:00:00

abstract：:We present a case of azathioprine-associated alveolitis diagnosed by gallium-67 scanning and transbronchial biopsy. The patient denied respiratory symptoms, exhibited spiking fevers, and had normal chest roentgenograms. Allopurinol inhibition of azathioprine metabolism may have been a contributing factor. ...

journal_title：Chest

authors： Krowka MJ,Breuer RI,Kehoe TJ

更新日期：1983-04-01 00:00:00

abstract：:The echocardiographic diagnosis of acute rupture of a papillary muscle is described. The pertinent findings included (1) decreased systolic motion of the posterior wall, (2) exaggerated septal motion, (3) left ventricular enlargement and pattern suggesting left ventricular diastolic overload, and (4) bizarre flutterin...

journal_title：Chest

authors： Ahmad S,Kleiger RE,Connors J,Krone R

更新日期：1978-02-01 00:00:00

abstract：:Thrombocytopenia is a common problem in cardiovascular patients, but the etiology and management of this condition may be different than those in other populations. Around the time that percutaneous coronary interventions are performed, the drugs most commonly associated with thrombocytopenia are the glycoprotein (GP)...

journal_title：Chest

authors： Matthai WH Jr

更新日期：2005-02-01 00:00:00

abstract：:Twenty-eight patients developed severe, progressive acute respiratory insufficiency despite aggressive application of conventional respiratory therapy. Application of increased PEEP (18 torr or greater) resulted in a significant decrease in QA/QT. Selection of the optimal levle of PEEP for each patient required seria...

journal_title：Chest

authors： Kirby RR,Downs JB,Civetta JM,Modell JH,Dannemiller FJ,Klein EF,Hodges M

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Correctly staging lung cancer is important because the treatment options and prognosis differ significantly by stage. Several noninvasive imaging studies and invasive tests are available. Understanding the accuracy, advantages, and disadvantages of the available methods for staging non-small cell lung cancer...

journal_title：Chest

authors： Silvestri GA,Gonzalez AV,Jantz MA,Margolis ML,Gould MK,Tanoue LT,Harris LJ,Detterbeck FC

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Population-based studies have documented an association between obesity and an increased prevalence of asthma in women. METHODS:We prospectively studied 58 obese women with a body mass index of > 30 kg/m(2), 24 of whom had asthma, who were enrolled in an intensive 6-month weight loss program to determine wh...

journal_title：Chest

authors： Aaron SD,Fergusson D,Dent R,Chen Y,Vandemheen KL,Dales RE

更新日期：2004-06-01 00:00:00

abstract：STUDY OBJECTIVE:We assessed whether transpleural methods for diagnosing peripheral lung cancer, such as needle aspiration or tumor excision, affect relapse and prognosis, because these techniques have potential to spread malignant cells from the tumor. DESIGN:A retrospective study. SETTING:National referral hospital....

journal_title：Chest

authors： Sawabata N,Maeda H,Ohta M,Hayakawa M

更新日期：2001-11-01 00:00:00

abstract：STUDY OBJECTIVES:Whereas pulmonary rehabilitation reduces symptoms and improves the quality of life of patients with COPD and is recommended in management guidelines, few patients have access to rehabilitation services. The purpose of this study was to investigate the effectiveness of increasing access to selected comp...

journal_title：Chest

authors： Coultas D,Frederick J,Barnett B,Singh G,Wludyka P

更新日期：2005-10-01 00:00:00

abstract：INTRODUCTION:Osteoporosis is a common condition in patients with end-stage lung disease, but little attention has been given to bone disease in patients with primary pulmonary hypertension (PPH). The purposes of this study were as follows: (1) to determine the prevalence of osteoporosis in patients with severe PPH befo...

journal_title：Chest

authors： Tschopp O,Schmid C,Speich R,Seifert B,Russi EW,Boehler A

更新日期：2006-04-01 00:00:00

abstract：STUDY OBJECTIVES:Autopsy evaluation of tracheobronchomalacia (TBM) in patients with Duchenne muscular dystrophy (DMD) who were receiving long-term ventilation through uncuffed tracheostomies. DESIGN:Necropsies were performed in seven patients with DMD who had received positive-pressure ventilation through uncuffed tra...

journal_title：Chest

authors： Baydur A,Kanel G

更新日期：2003-04-01 00:00:00

abstract：:We studied the reproducibility of tests of RM performance in normal elderly subjects and compared their performance with that of patients with COPD. The RM strength was measured as MIP and MEP. The RM endurance was measured using a two-minute incremental threshold loading test. The max load, the average Ppk as %MIP at...

journal_title：Chest

authors： Morrison NJ,Richardson J,Dunn L,Pardy RL

更新日期：1989-01-01 00:00:00

abstract：STUDY OBJECTIVES:Preoperative renal dysfunction is a risk factor for adverse events in cardiac surgery. This study compared creatinine clearance (ClCr), estimated from the Cockroft and Gault formula, and plasma creatinine level as predictors of outcome after cardiac surgery. DESIGN:Prospective, observational. SETTING...

journal_title：Chest

authors： Wang F,Dupuis JY,Nathan H,Williams K

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Lymph node status is a major determinant of stage and survival in patients with lung cancer; however, little information is available about the expected yield of a mediastinal lymphadenectomy. METHODS:The American College of Surgeons Oncology Group Z0030 prospective, randomized trial of mediastinal lymph no...

journal_title：Chest

authors： Darling GE,Allen MS,Decker PA,Ballman K,Malthaner RA,Inculet RI,Jones DR,McKenna RJ,Landreneau RJ,Putnam JB Jr

更新日期：2011-05-01 00:00:00

abstract：STUDY OBJECTIVES:Surgical resection remains the treatment of choice for anatomically resectable non-small cell lung cancer. However, the presence of associated comorbid conditions increases the risk of death and surgical complications. Several studies have evaluated the usefulness of preoperative exercise testing for p...

journal_title：Chest

authors： Win T,Jackson A,Sharples L,Groves AM,Wells FC,Ritchie AJ,Laroche CM

更新日期：2005-04-01 00:00:00

abstract：:The history holds the central role in distinguishing among asthma, chronic bronchitis, and emphysema. A personal or family history of atopy, a history of seasonal worsening of disease in response to a known environmental agent, perhaps seasonal, and marked variability in the severity of airflow obstruction, often with...

journal_title：Chest

authors： Snider GL

更新日期：1985-01-01 00:00:00