Association of depression and life-sustaining treatment preferences in patients with COPD.

abstract：:Caveolae are cell plasma membrane microdomains implicated in organizing and concentrating many signaling molecules. In the lung, caveolae are in endothelium, smooth muscle, fibroblasts, and pneumocytes. Caveolin is the main structural protein of caveolae. Caveolin 1 is down-regulated in transformed cells and may be a ...

journal_title：Chest

authors： Achcar RO,Demura Y,Rai PR,Taraseviciene-Stewart L,Kasper M,Voelkel NF,Cool CD

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Clinical resolution of ventilator-associated pneumonia (VAP) determines the duration of treatment and mechanical ventilation. The aim of this study was to evaluate the influence of organisms and their susceptibility to treatment on outcomes. METHODS:Prospective observational study in three teaching ICUs. Si...

journal_title：Chest

authors： Vidaur L,Planas K,Sierra R,Dimopoulos G,Ramirez A,Lisboa T,Rello J

更新日期：2008-03-01 00:00:00

abstract：:This study describes an unusual patient with X-linked Alport syndrome (XLAS) in whom diffuse alveolar hemorrhage (DAH) developed as a complication of alemtuzumab therapy following renal transplantation. A 26-year-old man with XLAS underwent retransplantation with a cadaveric renal allograft. He received alemtuzumab th...

journal_title：Chest

authors： Sachdeva A,Matuschak GM

更新日期：2008-06-01 00:00:00

abstract：STUDY OBJECTIVES:To characterize the prevalence of undiagnosed pulmonary hypertension in patients with limited and diffuse scleroderma. DESIGN:Prospective cross-sectional study. SETTING:University-based outpatient clinic. PATIENTS:Thirty-four consecutive patients with limited (n = 29) or diffuse (n = 5) scleroderma ...

journal_title：Chest

authors： Battle RW,Davitt MA,Cooper SM,Buckley LM,Leib ES,Beglin PA,Tischler MD

更新日期：1996-12-01 00:00:00

abstract：:We reviewed the inpatient records of 139 adult patients with leukemia to determine the incidence of opportunistic infections in immunocompromised patients and the pattern of roentgenographic involvement of such infections. There were 98 parenchymal infiltrates identified, including 43 episodes of local disease and 55 ...

journal_title：Chest

authors： Tenholder MF,Hooper RG

更新日期：1980-09-01 00:00:00

abstract：STUDY OBJECTIVES:We investigated the role of two leukotriene B4 (LTB4) receptors, BLT1 and peroxisome proliferator-activated receptor (PPAR)-alpha, in conferring the susceptibility to develop COPD in smokers. Proinflammatory LTB4 activities are mediated by BLT1, while the inactivation of LTB4 is promoted by PPARalpha. ...

journal_title：Chest

authors： Marian E,Baraldo S,Visentin A,Papi A,Saetta M,Fabbri LM,Maestrelli P

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Pulmonary artery remodeling triggered by alveolar hypoxia is considered the main mechanism of pulmonary hypertension (PH) in COPD patients. We hypothesized that the risk for PH in COPD is increased by an elevation in the proinflammatory cytokines interleukin (IL)-6, monocyte chemoattractant protein-1 (MCP-1)...

journal_title：Chest

authors： Chaouat A,Savale L,Chouaid C,Tu L,Sztrymf B,Canuet M,Maitre B,Housset B,Brandt C,Le Corvoisier P,Weitzenblum E,Eddahibi S,Adnot S

更新日期：2009-09-01 00:00:00

abstract：STUDY OBJECTIVES:This study was conducted to investigate whether intraoperative blood transfusions affect the release of proinflammatory mediators in patients undergoing cardiac surgery. Therefore, we measured plasma levels of bactericidal permeability increasing protein (BPI) as a marker of neutrophil activation, inte...

journal_title：Chest

authors： Fransen E,Maessen J,Dentener M,Senden N,Buurman W

更新日期：1999-11-01 00:00:00

abstract：:Numerous alterations in the sympathetic nervous system have been reported in patients with obstructive sleep apnea. It is unclear whether such alterations can be attributed to the respiratory disturbance itself, the resulting hypoxia, or disruption of sleep. We examined urinary norepinephrine levels in 45 individuals ...

journal_title：Chest

authors： Dimsdale JE,Coy T,Ancoli-Israel S,Mills P,Clausen J,Ziegler MG

更新日期：1997-03-01 00:00:00

abstract：STUDY OBJECTIVE:The chronically critically ill (CCI) are a subgroup of critically ill patients who have survived an acute critical illness but remain profoundly debilitated and ventilator dependent. We have previously shown that CCI patients have a very high prevalence of bone hyperresorption. The objective of this pre...

journal_title：Chest

authors： Nierman DM,Mechanick JI

更新日期：2000-09-01 00:00:00

abstract：STUDY OBJECTIVES:To describe the prevalence of parental prompting to smoke (eg, parent requests that their child light the parent's cigarette in his/her own mouth) in a sample of families, and to assess the agreement between child and parent reports of the prompting behaviors. DESIGN, SETTING, AND PARTICIPANTS:A total...

journal_title：Chest

authors： Laniado-Laborín R,Candelaria JI,Villaseñor A,Woodruff SI,Sallis JF

更新日期：2004-02-01 00:00:00

abstract：PURPOSES:To determine the diagnostic accuracy of ultrasound in the diagnosis of pneumothorax in patients with COPD with particular regard to false-positive diagnoses. MATERIALS AND METHODS:This was a single-center, prospective, blinded study. Nine patients with pneumothorax, 9 patients with cystic fibrosis, 17 patient...

journal_title：Chest

authors： Slater A,Goodwin M,Anderson KE,Gleeson FV

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:Cognitive impairment increases with age, as do many serious illnesses requiring intensive care. Little is known, however, about physician recognition of preexisting cognitive impairment in the ICU and which patient factors may play a role in physician recognition. DESIGN:Cross-sectional comparative study. ...

journal_title：Chest

authors： Pisani MA,Redlich C,McNicoll L,Ely EW,Inouye SK

更新日期：2003-12-01 00:00:00

abstract：:A pulmonary arteriovenous malformation was embolized in a patient with hereditary hemorrhagic telangiectasia. Several unusual complications, including early deflation of a detachable balloon, migration of a coil, and development of severe pulmonary hypertension, occurred. Pulmonary hypertension was attributed to a coe...

journal_title：Chest

authors： Haitjema T,ten Berg JM,Overtoom TT,Ernst JM,Westermann CJ

更新日期：1996-05-01 00:00:00

abstract：:The relationship between coffee consumption and the prevalence of bronchial asthma has been evaluated using data from the 1983 Italian National Health Survey, based on 72,284 individuals aged over 15 years randomly selected within strata of geographic area, size of the place of residence and of the household in order ...

journal_title：Chest

authors： Pagano R,Negri E,Decarli A,La Vecchia C

更新日期：1988-08-01 00:00:00

abstract：:The current epidemic of acquired immune deficiency syndrome (AIDS) raises numerous public policy concerns for the medical community. The issues can be divided into two groups. Those concerns which require both immediate action and results are referred to as short-term issues. Those issues whose results will not be for...

journal_title：Chest

authors： Panem S

更新日期：1984-03-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the cause of pulmonary hypertension (PH) in systemic sclerosis (SSc) patients since PH can occur because of pulmonary arteriopathy, pulmonary parenchymal destruction, and left ventricular cardiac dysfunction. DESIGN AND SETTING:Consecutive case series in a university hospital. PATIENTS:N...

journal_title：Chest

authors： Strange C,Bolster M,Mazur J,Taylor M,Gossage JR,Silver R

更新日期：2000-10-01 00:00:00

abstract：:In order to determine the effect of electrode placement and standing on the 12-lead electrocardiogram required prior to exercise testing, 104 male patients with stable coronary heart disease were studied. Electrocardiograms were recorded with two different placements of the arm electrodes commonly used for exercise te...

journal_title：Chest

authors： Gamble P,McManus H,Jensen D,Froelicher V

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Some studies have demonstrated that the function of the growth hormone (GH)-insulin-like growth factor (IGF)-1 axis is significantly impaired in patients with oral corticosteroid (CS)-induced osteoporosis. The aim of study was to investigate the effects of long-term therapy with inhaled CSs (ICSs) on the hyp...

journal_title：Chest

authors： Malerba M,Bossoni S,Radaeli A,Mori E,Bonadonna S,Giustina A,Tantucci C

更新日期：2005-02-01 00:00:00

abstract：STUDY OBJECTIVES:To analyze the physiologic effects and tolerance of mechanical insufflation-exsufflation (MI-E) by means of mechanical cough assistance (Cough Assist; JH Emerson Company; Cambridge, MA) for children with neuromuscular disease. DESIGN:Prospective clinical trial. SETTING:Physiology laboratory of a pedi...

journal_title：Chest

authors： Fauroux B,Guillemot N,Aubertin G,Nathan N,Labit A,Clément A,Lofaso F

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Severe pneumonia requiring ICU admission has not been well characterized with respect to long-term outcomes or predictors thereof. We examined the association between premorbid functional status and mortality in patients with severe pneumonia. METHODS:From 2000 to 2002, a population-based cohort of adults w...

journal_title：Chest

authors： Sligl WI,Eurich DT,Marrie TJ,Majumdar SR

更新日期：2011-01-01 00:00:00

abstract：:Seventy-two consecutive adult asthmatic patients seen in the Pulmonary Clinic at Rhode Island Hospital were tested for atopy by prick test with 14 standard aeroallergens and by in vitro total and specific IgE determinations (FAST). A total of 58.3 percent of patients were found to be atopic by these tests. There was a...

journal_title：Chest

authors： Kalliel JN,Goldstein BM,Braman SS,Settipane GA

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Interest in airways inflammatory disease has increasingly focused on innate immunity. We investigated several components of innate immunity in induced sputum of patients with cystic fibrosis (CF), COPD, and asthma, and healthy control subjects. METHODS:Twenty eight patients with mild CF lung disease (age > ...

journal_title：Chest

authors： Xiao W,Hsu YP,Ishizaka A,Kirikae T,Moss RB

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Precapillary pulmonary hypertension (PH) is a complication of pulmonary Langerhans cell histiocytosis (PLCH) associated with increased mortality. However, outcomes and efficacy of pulmonary arterial hypertension (PAH) therapies in patients with PH complicating PLCH(PLCH-PH) remain unknown. METHODS:Consecuti...

journal_title：Chest

authors： Le Pavec J,Lorillon G,Jaïs X,Tcherakian C,Feuillet S,Dorfmüller P,Simonneau G,Humbert M,Tazi A

更新日期：2012-11-01 00:00:00

abstract：:A 66-year-old woman was cared for at two referral institutions following a witnessed cardiac arrest in a local emergency department. Despite aggressive initial care, she failed to regain consciousness during a 28-day course. Based on an erroneous neurologic diagnosis of anoxic encephalopathy, pessimism regarding likel...

journal_title：Chest

authors： Dunn WF,Adams SC,Adams RW

更新日期：2008-05-01 00:00:00

abstract：:An unusual site and cause of disabling inspiratory and expiratory airflow limitation mimicking fixed upper airway obstruction is reported in two patients with sarcoidosis who had stenosis of almost the entire lengths of both main bronchi. The observed flows were consistent with a cross sectional airway diameter of 3 m...

journal_title：Chest

authors： Miller A,Brown LK,Teirstein AS

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Studies evaluating the dose of epinephrine required to optimize return of spontaneous circulation and survival after CPR have shown that doses greater than recommended by advanced cardiac life support (ACLS) improve coronary perfusion pressure and short-term resuscitation rates. Since survival has not improv...

journal_title：Chest

authors： Rivers EP,Wortsman J,Rady MY,Blake HC,McGeorge FT,Buderer NM

更新日期：1994-11-01 00:00:00

abstract：:The association between pulmonary impairment and all-cause mortality was investigated among white subjects in a follow-up study of a large national cohort. Pulmonary function was measured during the National Health and Nutrition Examination Survey (NHANESI) (1971 to 1975); subsequent mortality information was obtained...

journal_title：Chest

authors： Bang KM,Gergen PJ,Kramer R,Cohen B

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Patients with usual interstitial pneumonia (UIP) associated with collagen vascular disease (CVD) have been reported to have a better prognosis than those with idiopathic pulmonary fibrosis with a UIP pattern (IPF/UIP) seen on histology. The aim of this study was to evaluate the pathologic and radiologic diff...

journal_title：Chest

authors： Song JW,Do KH,Kim MY,Jang SJ,Colby TV,Kim DS

更新日期：2009-07-01 00:00:00

abstract：:Lung scans with technetium sulfur colloid were performed in ten patients with life-threatening hemoptysis and nondiagnostic chest roentgenograms. Localized deposition of radionuclide was demonstrated in five of the six patients who were studied during active bleeding. These abnormalities were confirmed bronchoscopical...

journal_title：Chest

authors： Haponik EF,Rothfeld B,Britt EJ,Bleecker ER

更新日期：1984-08-01 00:00:00