Effects of exposure to a circularly polarized 50-Hz magnetic field on plasma and pineal melatonin levels in rats.

Abstract:

:We sought to determine whether a 6-week exposure to a 50-Hz rotating magnetic field influences melatonin synthesis by 11-18 week-old Wistar-King male rats. Rats were exposed continuously to a rotating magnetic field at 1, 5, 50, or 250 microT (spatial vector rms) for 6 weeks, except for twice-weekly breaks of about 2 h for cleaning of cages and feeding. The rats were housed in exposure and sham-exposure facilities, which were located in the same room, under a 12:12 light-dark photoperiod (lights on at 06:00 h). The room was constantly illuminated by 4 small, dim red lights (< 0.07 lux in dark period). Levels of plasma and pineal gland melatonin were determined by radioimmunoassay. A significant decrease of melatonin was observed between the control group and groups exposed to a magnetic field at a flux density in excess of 1 microT during the night time, but no statistical differences were found among the exposed groups. These results indicate that subchronic exposure of albino rats to a 50-Hz rotating magnetic field influences melatonin production and secretion by the pineal gland.

journal_name

Bioelectromagnetics

journal_title

Bioelectromagnetics

authors

Kato M,Honma K,Shigemitsu T,Shiga Y

doi

10.1002/bem.2250140203

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

97-106

issue

2

eissn

0197-8462

issn

1521-186X

journal_volume

14

pub_type

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