Fentanyl attenuates porcine coronary arterial contraction through M3-muscarinic antagonism.

abstract：BACKGROUND:β3 containing γ-aminobutyric acid type A receptors (GABA(A)-Rs) mediate behavioral end points of IV anesthetics such as immobility and hypnosis. A knockout mouse with targeted forebrain deletion of the β3 subunit of the GABA(A)-R shows reduced sensitivity to the hypnotic effect of etomidate, as measured by t...

journal_title：Anesthesia and analgesia

authors： Rau V,Oh I,Liao M,Bodarky C,Fanselow MS,Homanics GE,Sonner JM,Eger EI 2nd

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Although studies have compared safety and outcomes of radial artery cannulation with other arterial catheterization locations, there is insufficient information describing brachial artery catheterization. In this study, we characterized the perioperative use patterns and the complication rates associated wit...

journal_title：Anesthesia and analgesia

authors： Handlogten KS,Wilson GA,Clifford L,Nuttall GA,Kor DJ

更新日期：2014-02-01 00:00:00

abstract：:Large doses of morphine sulfate have been reported to cause myocardial lactate production and reduction in coronary blood flow in animals. Similar effects with clinical doses in man would significantly alter the management of cardiac patients. Eleven adult patients with significant coronary arterial disease and normal...

journal_title：Anesthesia and analgesia

authors： Sethna DH,Moffitt EA,Gray RJ,Bussell J,Raymond M,Conklin C,Shell WE,Matloff JM

更新日期：1982-02-01 00:00:00

abstract：:The purpose of this study was to examine the effects of alfentanil applied to the surface of the spinal cord and the effects of intravenously administered alfentanil on noxiously evoked activity of dorsal horn neurons. Extracellular single neuron recordings were obtained from wide dynamic range neurons in 26 decerebra...

journal_title：Anesthesia and analgesia

authors： Matsumoto M,Collins JG,Kitahata LM,Yuge O,Tanaka A

更新日期：1986-02-01 00:00:00

abstract：:To determine whether concentrations of diethylaminoethanol (DEAE) and procaine below those that reduce the amplitude of action potentials might alter the excitability of brain cells, a single microelectrode intracellular recording technique was used to measure firing threshold and action potential amplitude of pyramid...

journal_title：Anesthesia and analgesia

authors： Butterworth JF 4th,Cole LR

更新日期：1990-10-01 00:00:00

abstract：:Including positive end-expiratory pressure (PEEP) in the manual resuscitation bag (MRB) may render manual hyperinflation (MHI) ineffective as a secretion maneuver technique in mechanically ventilated patients. In this study we aimed to determine the effect of increased PEEP or decreased compliance on peak expiratory f...

journal_title：Anesthesia and analgesia

authors： Savian C,Chan P,Paratz J

更新日期：2005-04-01 00:00:00

abstract：:Cerebral computer tomography is a recently introduced neuroradiologic procedure involving tomographic x-rays of horizontal brain sections. Although most adults undergo the procedure without anesthesia, children and uncooperative adults must be given general anesthesia for absolute immobility. Of 84 procedures under ge...

journal_title：Anesthesia and analgesia

authors： Ferrer-Brechner T,Winter J

更新日期：1977-05-01 00:00:00

abstract：:The purpose of this study was to determine if the addition of sufentanil would improve the quality of analgesia obtained with 0.125% epidural bupivacaine infusions given to women in active labor. Forty healthy laboring women were randomly assigned to two equal groups. Group 1 had epidural analgesia instituted with the...

journal_title：Anesthesia and analgesia

authors： Phillips G

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Because children's anxiety influences pain perception, perioperative anxiety should be evaluated in clinical practice with a unique, useful, and valid tool to optimize pain management. In this study, we evaluated psychometric properties of the visual analog scale (VAS)-anxiety for children and to study its p...

journal_title：Anesthesia and analgesia

authors： Bringuier S,Dadure C,Raux O,Dubois A,Picot MC,Capdevila X

更新日期：2009-09-01 00:00:00

abstract：:Preoperative local anesthetic blockade of somatosensory pathways involved with skin incision and other noxious perioperative stimuli may "preempt" or attenuate the postoperative pain response. Since the Pfannenstiel incision lies within the L1 dermatome, bilateral ilioinguinal, iliohypogastric nerve blocks (IINBs) sho...

journal_title：Anesthesia and analgesia

authors： Huffnagle HJ,Norris MC,Leighton BL,Arkoosh VA

更新日期：1996-01-01 00:00:00

abstract：:The effects of gestational age (GA) and plasma protein concentrations on the plasma protein binding of fentanyl and alfentanil were studied in preterm and term neonates. Binding experiments were performed using split-cell equilibrium dialysis. Fentanyl and alfentanil concentrations were measured using specific radioim...

journal_title：Anesthesia and analgesia

authors： Wilson AS,Stiller RL,Davis PJ,Fedel G,Chakravorti S,Israel BA,McGowan FX Jr

更新日期：1997-02-01 00:00:00

abstract：:We evaluated the effects of adding clonidine for continuous peripheral nerve infusions. Sixty patients undergoing total knee arthroplasty under combined single-injection sciatic block and continuous femoral infusion were randomly allocated to three groups: block induction with 0.75% ropivacaine followed by 0.2% ropiva...

journal_title：Anesthesia and analgesia

authors： Casati A,Vinciguerra F,Cappelleri G,Aldegheri G,Fanelli G,Putzu M,Chelly JE

更新日期：2005-03-01 00:00:00

abstract：:Two concentrations of etidocaine (1 and 1.5%) and of pH-adjusted bupivacaine (0.5 and 0.75%, pH 6.8), all fortified with hyaluronidase, were compared as local anesthetics in regional ophthalmic surgery for cataract extraction. The series comprised 160 patients assigned randomly to four groups (n = 40). Each patient re...

journal_title：Anesthesia and analgesia

authors： Sarvela PJ

更新日期：1993-07-01 00:00:00

abstract：:The nucleus raphe magnus (NRM) is an important descending pain inhibitory system. We postulated that the analgesic action of supraspinally administered opiates results from increased descending inhibitory control of the NRM. We tested whether fentanyl activates NRM neurons in the rat slice preparation using extra-cell...

journal_title：Anesthesia and analgesia

authors： Ohta Y,Alojado ME,Kemmotsu O

更新日期：1995-05-01 00:00:00

abstract：:The purpose of this study was to measure and compare the relationship of cardiovascular depression and dose during equal potent levels of halothane and isoflurane anesthesia in neonates (n = 19) (16.7 +/- 6.9 days) and infants (n = 54) (6.1 +/- 3.1 mo). Seventy-three children had heart rate, arterial blood pressure, a...

journal_title：Anesthesia and analgesia

authors： Murray DJ,Forbes RB,Mahoney LT

更新日期：1992-03-01 00:00:00

abstract：:Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery. Fifty-six patients scheduled for coronary artery bypass grafting (CABG), were included in a randomized, double-blind study. The patients were anesthetized wit...

journal_title：Anesthesia and analgesia

authors： Sellevold OF,Berg EM,Levang OW

更新日期：1995-11-01 00:00:00

abstract：:Using a standardized technique, spinal anesthesia was induced in 50 term parturients to study the correlation between patient height, weight, and body mass index (BMI) and the spread of sensory blockade. All patients received 12 mg hyperbaric bupivacaine while in the right lateral decubitus position on a horizontal op...

journal_title：Anesthesia and analgesia

authors： Norris MC

更新日期：1988-06-01 00:00:00

abstract：IMPLICATIONS:The performance of regional blockade on a patient with a preexisting neurologic condition or a history of neurologic complications after regional anesthesia is controversial. We present a case of recurring brachial plexus neuropathy in a diabetic patient after two shoulder procedures performed 4 mo apart. ...

journal_title：Anesthesia and analgesia

authors： Horlocker TT,O'Driscoll SW,Dinapoli RP

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:In this study, we hypothesized that leg positioning and distal tourniquet application, when compared with neutral positioning of the leg, alters the efficacy of sciatic nerve block performed by the double-stimulation technique. METHODS:Ninety randomized, consecutive, ASA physical status I to III patients un...

journal_title：Anesthesia and analgesia

authors： Sertoz N,Deniz MN,Ayanoglu HO

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Cannabinoid agonists induce norepinephrine release in central, spinal, and peripheral sites. Previous studies suggest an interaction between the cannabinoid and adrenergic systems on antinociception. In this study, we sought to verify whether the CB1 and CB2 cannabinoid receptor agonists anandamide and N-pal...

journal_title：Anesthesia and analgesia

authors： Romero TR,Resende LC,Guzzo LS,Duarte ID

更新日期：2013-02-01 00:00:00

abstract：:The common treatment for postoperative pain is prescription opioids. Yet, these drugs have limited effect in preventing chronic pain from surgical intervention and have in part contributed to the opioid epidemic. Recently, preemptive analgesia and multimodal analgesia have been proposed with widely gained acceptance i...

journal_title：Anesthesia and analgesia

authors： Horn A,Kaneshiro K,Tsui BCH

更新日期：2020-03-01 00:00:00

abstract：UNLABELLED:Morbidly obese (MO) patients undergoing laparoscopy have lower PaO(2) compared with normal-weight (NW) patients. We hypothesized that increases in tidal volume (V(T)) or respiratory rate (RR) would improve oxygenation. All measurements were performed at: 1) baseline: V(T) 600-700 mL and 10 breaths/min, 2) do...

journal_title：Anesthesia and analgesia

authors： Sprung J,Whalley DG,Falcone T,Wilks W,Navratil JE,Bourke DL

更新日期：2003-07-01 00:00:00

abstract：:A new mode of pulmonary ventilation called intratracheal pulmonary ventilation (ITPV) was studied. Briefly, a continuous flow of air/oxygen is introduced through a small catheter, the tip of which is positioned at the carina, with a diffuser mounted at its distal end. A timed expiration valve, when closed, provides fo...

journal_title：Anesthesia and analgesia

authors： Kolobow T,Powers T,Mandava S,Aprigliano M,Kawaguchi A,Tsuno K,Mueller E

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Neonatal exposure to sevoflurane induces neurobehavioral and neuroendocrine abnormalities in exposed male rats (generation F0) and neurobehavioral, but not neuroendocrine, abnormalities in their male, but not female, offspring (generation F1). These effects of sevoflurane are accompanied by a hypermethylated...

journal_title：Anesthesia and analgesia

authors： Xu N,Lei L,Lin Y,Ju LS,Morey TE,Gravenstein N,Yang J,Martynyuk AE

更新日期：2020-10-01 00:00:00

abstract：UNLABELLED:Nitric oxide (NO) may play an important role in central and peripheral nociceptive processes. However, its contribution to peripheral antinociception is still not clear. In the present study, we investigated the effect of peripherally administered FK409, a spontaneous NO releaser, and its interaction with pe...

journal_title：Anesthesia and analgesia

authors： Nozaki-Taguchi N,Yamamoto T

更新日期：1998-02-01 00:00:00

abstract：:The effects of commercial and crystalline solutions of chloroprocaine (CP) (1.6 X 10(-3)-0.4 X 10(-3)M) and sodium bisulfite (SB) (0.8 X 10(-3)-0.08 X 10(-3)M) were studied on the multiplication of human neuroblastoma cells. These cells were chosen because of putative neurotoxicity associated with CP; cell multiplicat...

journal_title：Anesthesia and analgesia

authors： Seravalli E,Lear E

更新日期：1987-10-01 00:00:00

abstract：:Children have increased anxiety during the preoperative period. The administration of oral premedication to children is often met with apprehension, reluctance, or refusal. We sought to determine whether giving a small toy to the children would decrease the anxiety associated with taking oral premedication. This was a...

journal_title：Anesthesia and analgesia

authors： Golden L,Pagala M,Sukhavasi S,Nagpal D,Ahmad A,Mahanta A

更新日期：2006-04-01 00:00:00

abstract：:Education is the fundamental process used to develop and maintain the professional skills of physicians. Medical students, residents, and fellows are expected to learn considerable amounts of information as they progress toward board certification. Established practitioners must continue to learn in an effort to remai...

journal_title：Anesthesia and analgesia

authors： Weidman J,Baker K

更新日期：2015-12-01 00:00:00

abstract：:This randomized, prospective clinical study investigated the effects of supplemental inspired oxygen on arterial hemoglobin desaturation and myocardial ischemia in premedicated patients who have critical coronary artery stenosis, identified predictors for these adverse events, and examined the temporal relationship be...

journal_title：Anesthesia and analgesia

authors： Kavanagh BP,Cheng DC,Sandler AN,Chung F,Lawson S,Ong D

更新日期：1993-05-01 00:00:00

abstract：:Previous studies have suggested that shocks of 5-10 J are required for direct ventricular defibrillation during open heart surgery. However, the efficacy of shocks of less than 5 J, the effects of thermal, biochemical, and temporal factors, and the influence of disease process on defibrillation have not been fully inv...

journal_title：Anesthesia and analgesia

authors： Lake CL,Sellers TD,Nolan SP,Crosby IK,Wellons HA Jr,Crampton RS

更新日期：1984-08-01 00:00:00