Abstract:
:Health care workers may be occupationally exposed to known and suspected teratogens including viruses, anesthetic gases, sterilants, mercury, and x-radiation. To assess the risk of congenital defects among offspring of health care workers, we analyzed parental occupational histories for 4,915 case babies with congenital defects, registered during the years 1968-1980 by the Metropolitan Atlanta Congenital Defects Program (MACDP) registry, and for 3,027 control babies born without defects during the same period. Offspring of mothers employed in a nursing occupation during the periconceptional period had a modest excess risk of having at least one congenital defect (relative risk [RR] = 1.42; 95% confidence interval [CI] 1.06-1.88); the offspring were at statistically significant increased risk of having anencephaly or spina bifida (RR = 2.00; 95% CI 1.01-4.30), coarctation of the aorta (RR = 2.06; 95% CI 1.10-3.82), genital system defects (RR = 1.61; 95% CI 1.03-2.53), and urinary system defects (RR = 3.43; 95% CI 1.41-8.34). These associations were not confounded by maternal age, education, or alcohol consumption. Offspring of mothers employed in administrative or clerical jobs in the health care industry also had a modest excess risk of defects (RR = 1.35; 95% CI 0.96-1.90), including a statistically significant excess risk of limb defects. We also found associations between neural tube defects and potential exposure to anesthetic gases and to x-radiation, but each association was based on only three case babies of potentially exposed parents. We found no associations between defects and paternal health care employment, except for a few individual defects, and these were based on small numbers of exposed subjects. Only one of five previous studies reviewed found an increased risk of congenital defects among offspring of nurses, but three of the four negative studies had substantially smaller sample sizes than the present study. Detection bias may be a possible explanation for the apparent excess risk of certain defects among offspring of nurses.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Matte TD,Mulinare J,Erickson JDdoi
10.1002/ajim.4700240103subject
Has Abstractpub_date
1993-07-01 00:00:00pages
11-23issue
1eissn
0271-3586issn
1097-0274journal_volume
24pub_type
杂志文章abstract::A series of 206 necropsies in Western Australia (WA) have had routine counts made of asbestos bodies in samples of lung tissue using conventional light microscopy. Thirty-two cases had worked in the asbestos industry at Wittenoom, WA and (log) counts of asbestos bodies in their lung tissue correlated well with estimat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280405
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:An epidemic of asbestos-related diseases is ongoing worldwide. Mortality from malignant pleural neoplasms in Italy was analyzed, to estimate the health impact of asbestos at national and local level. METHODS:Mortality from ICD-9 code 163 was considered, in the time-window 1995-2002, using National Bureau of...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.21015
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Latino residential construction workers experience high rates of occupational fatality and injury. Work safety climate is an especially important consideration for improving the safety of these immigrant workers. This analysis describes work safety climate among Latino residential construction workers, delin...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22058
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Opioid use is rising in the US and may cause special problems in workers compensation cases, including addiction and preventing a return to work after an injury. OBJECTIVE:This study evaluates a physician-level intervention to curb opioid usage. An insurer identified patients with out-of-guideline opioid ut...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22779
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Occupational exposure to lead and solvents has declined steadily over the past 20 years, however, construction workers continue to be exposed to these neurotoxicants. The purpose of this study was to investigate the cognitive effects of chronic occupational exposure to lead and solvents. METHOD:Based on K-X...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10287
更新日期:2003-10-01 00:00:00
abstract::In a survey of chronic respiratory symptoms and airflow obstruction of a rural population aged 20-65 years, the effects of both farming and, in particular, the exposure to grain dust on the respiratory health of the people was examined. Of the 1,892 subjects (82% of the eligible population) studied, 924 were males and...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700150103
更新日期:1989-01-01 00:00:00
abstract::A 5-year prospective analysis tests the hypothesis that coal miners who have impaired respiratory health also experience greater numbers of disability days due to occupational injury. Occupational and respiratory health information collected for the period 1977 through 1981 by the National Institute for Occupational S...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700070409
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Many newly constructed green buildings (GB) are certified using the United States Green Building Council (USGBC) Leadership in Energy and Environmental Design (LEED) rating system for new construction and major renovation which focuses on architectural and mechanical design to conserve energy, reduce environ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22166
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:For truck drivers, distracted driving is a workplace behavior that increases occupational injury risk. We propose safety climate as an appropriate lens through which researchers can examine occupational distracted driving. METHODS:Using a mixed methods study design, we surveyed truck drivers using the Safet...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22473
更新日期:2015-07-01 00:00:00
abstract::In view of the increasing incidence of diseases such as gastritis and ulcers in workers exposed to noise, we assessed whether noise does in fact affect gastric secretion. Then, considering the conflicting findings published on the effects of noise on gastric secretion, we also investigated whether the response was rel...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260310
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:While low dose computed tomography (LDCT) screening for lung cancer is recommended for high-risk smokers, ages 55-74 years, information about asbestos exposure may not be routinely elicited. Asbestos exposure is associated with declining respiratory function over time; however, the effect of a history of asb...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22571
更新日期:2016-03-01 00:00:00
abstract::In adults, lead toxicity is most commonly caused by occupation in a lead industry. Whereas lead toxicity has been described in workers who are involved in bridge rehabilitation, as of this date there has been no systematic evaluation published regarding the conditions responsible for lead toxicity in ironworkers. This...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199711)32:5<540::aid-ajim1
更新日期:1997-11-01 00:00:00
abstract::The relationship between the time-weighted average intensity of exposure to toluene and o-cresol concentration in shift-end urine was investigated in nearly 500 factory workers of both sexes in China, together with a similar number of nonexposed control subjects. Toluene concentration (25 ppm as geometric mean and 550...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250509
更新日期:1994-05-01 00:00:00
abstract::This commentary challenges a recently published perception that Dr. Le Roy Upson Gardner had not actually discovered in 1942 that inhaled chrysotile fibers could induce malignant neoplasia in mice. The handwritten laboratory notes and some of Dr. Gardner's slides have recently been found. They verify that the tumors h...
journal_title:American journal of industrial medicine
pub_type: 传,历史文章,杂志文章
doi:10.1002/ajim.4700270413
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:Harvesting of blueberries is associated with musculoskeletal injury. This study assessed the effects of several alternative designs of the harvesting rake. METHODS:A community-based work team selected rake design for intervention and pilot tested potential design modifications to the blueberry harvesting ra...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20554
更新日期:2008-04-01 00:00:00
abstract::Very sensitive and precise analytical methods for measuring total porphyrin excretion and the relative amounts of different porphyrins in urine are required in order to monitor the biological effects of porphyrinogenic substances in workers and the general population. Many analytical steps of a HPLC method for measuri...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700040409
更新日期:1983-01-01 00:00:00
abstract::Mitoplasts from rabbit bone marrow cells in vitro incubated with benzene metabolites showed a concentration-dependent inhibition of mitochondrial RNA synthesis. The 50% molar inhibitory concentration for each metabolite was determined to be p-benzoquinone, 2 X 10(-6); phenol, 2.5 X 10(-5); hydroquinone, 5 X 10(-5); ca...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700070512
更新日期:1985-01-01 00:00:00
abstract::In the past 10 years there has been growing awareness among occupational health professionals worldwide of the large burden of illness associated with musculoskeletal disorders of the neck and upper limbs. It has been suggested that these disorders are associated with highly repetitive work and are due, at least in pa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,meta分析
doi:10.1002/ajim.4700190111
更新日期:1991-01-01 00:00:00
abstract::We investigated an outbreak of irritative and neurotoxic symptoms associated with exposure to asphalt fumes in a commercial lighting factory; 27 symptomatic female workers were clinically assessed including hematologic testing. When compared with a laboratory reference group (n = 107), the workers' mean platelet volum...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250214
更新日期:1994-02-01 00:00:00
abstract::In conjunction with industrial hygiene surveys, mutagenicity studies were performed for the airborne contaminants in three polyurethane manufacturing plants. Airborne particles were collected on glass-fiber filters with Hi-Vol pumps from different locations in each plant. Gases were collected in multiple-sorbent cartr...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700110410
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:This study explored perspectives of Northeast commercial lobstermen regarding the use of personal flotation devices (PFDs). Researchers sought to identify factors contributing to low PFD use, and motivators that could lead to increased use of PFDs. METHODS:This qualitative research (n = 72) included 25 comm...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22537
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Many authorities are concerned about the rising use and the potential overuse of opioid pain medications. A study of opioid prevalence and dosage in Ohio's workers' compensation (WC) system was conducted, with comparisons made to opioid use in other WC and non-WC settings. METHODS:Systematic literature revi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.21021
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:The Fogarty International Center (FIC) of the United States National Institutes of Health includes the International Training and Research in Environmental and Occupational Health (ITREOH) Program. The "International Training Program in Environmental Toxicology and Public Health" Center, funded in 2002 is ba...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22044
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tubercul...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23066
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Acoustic neuroma is the intracranial tumor subtype showing the highest relative risk in relation to ionizing radiation but other environmental risk factors are largely unknown. This study was performed to investigate the effect of power frequency magnetic fields. METHOD:A total of 793 cases between 1987 and...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20251
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Studies comparing different forms of asbestos are rare, and limited by the failure to compare results with unexposed populations. We compare autoimmune responses among former workers and residents of the crocidolite mining and milling town of Wittenoom, Western Australia, with an unexposed population. METHO...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22863
更新日期:2018-07-01 00:00:00
abstract::Fertility among men working in semiconductor manufacturing during 1984-89 was assessed in a 1990-91 cross-sectional study of eight companies. Men working in wafer fabrication rooms (fabs) (n = 241, 165 births) were compared to men in nonfabrication (nonfab) jobs (n = 447, 300 births). Results showed that 17% of fab me...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280618
更新日期:1995-12-01 00:00:00
abstract:OBJECTIVES:To assess changes in work characteristics, socioeconomic status inequalities in changes in work characteristics, and whether US workplaces are becoming more stressful. METHODS:We analyzed data from 5361 employed participants from the 2002, 2006, 2010, and 2014 NIOSH Quality of Work Life Surveys, based on re...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22971
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Use of worker's compensation (WC) as payer underestimates work-related (WR) injuries. We evaluated three methods to identify WR injuries: WC as payer, ICD-9-CM work-status codes E000.0/E000.1, and other ICD-9-CM external cause codes. METHODS:We identified injury-related emergency department visits from Nort...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22984
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:The healthy survivor effect is a selection process whereby healthy workers are selectively retained in the work force while unhealthy workers are removed. Understanding this phenomenon is integral to the accurate assessment of exposure effects in occupational cohorts. To date, scarce information has been pub...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199904)35:4<343::aid-ajim4
更新日期:1999-04-01 00:00:00