Abstract:
BACKGROUND:Studies comparing different forms of asbestos are rare, and limited by the failure to compare results with unexposed populations. We compare autoimmune responses among former workers and residents of the crocidolite mining and milling town of Wittenoom, Western Australia, with an unexposed population. METHODS:ANA testing using indirect immunofluorescence was performed on randomly selected serum samples from Wittenoom workers or residents and compared with those from participants of another unexposed cohort study. RESULTS:ANA scores were higher in the Wittenoom participants compared with Busselton and the odds of being ANA positive was fivefold greater among Wittenoom participants than Busselton (OR 5.5, 95%CI 2.3-13.0). CONCLUSIONS:This study is the first to report increased ANA positivity among persons exposed exclusively to crocidolite. This finding of a high frequency of positive ANA tests among crocidolite-exposed subjects may be an indicator for an increased risk of systemic autoimmune diseases and needs further scrutiny.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Reid A,Franklin P,de Klerk N,Creaney J,Brims F,Musk B,Pfau Jdoi
10.1002/ajim.22863subject
Has Abstractpub_date
2018-07-01 00:00:00pages
615-620issue
7eissn
0271-3586issn
1097-0274journal_volume
61pub_type
杂志文章abstract::Several studies have indicated an increased risk for cancer of the urinary bladder among hairdressers. In a Danish linkage between census data and cancer register data both male and female hairdressers have an elevated risk for bladder cancer. The risk for lung cancer is close to unity, indicating that occupational fa...
journal_title:American journal of industrial medicine
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journal_title:American journal of industrial medicine
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journal_title:American journal of industrial medicine
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journal_title:American journal of industrial medicine
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更新日期:2005-05-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700030409
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journal_title:American journal of industrial medicine
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更新日期:1997-01-01 00:00:00
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journal_title:American journal of industrial medicine
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
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更新日期:1994-01-01 00:00:00
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更新日期:2004-08-01 00:00:00
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更新日期:2011-11-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700100509
更新日期:1986-01-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22749
更新日期:2017-09-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199908)36:2<317::aid-ajim1
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
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更新日期:1999-03-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
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journal_title:American journal of industrial medicine
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更新日期:1998-10-01 00:00:00
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journal_title:American journal of industrial medicine
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doi:10.1002/ajim.4700080422
更新日期:1985-01-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199809)34:3<220::aid-ajim3
更新日期:1998-09-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/1097-0274(200011)38:5<584::aid-ajim11>3.0.
更新日期:2000-11-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22651
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Exposure to dichloromethane (DCM or methylene chloride - CH₂ Cl₂ ) in paint strippers continues to be an avoidable source of morbidity and mortality. DCM has been under regulatory scrutiny by occupational and consumer product agencies since the identification of its carcinogenicity in the mid-1980s. METHODS...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22167
更新日期:2013-08-01 00:00:00
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journal_title:American journal of industrial medicine
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doi:10.1002/ajim.20425
更新日期:2007-02-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.22448
更新日期:2015-06-01 00:00:00
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journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199901)35:1<9::aid-ajim2>3
更新日期:1999-01-01 00:00:00