Abstract：
:A five-year total community study of lung cancer incidence by occupation revealed that 1) virtually all the cases occurred in smokers; 2) all major histologic types of lung cancer were strongly associated with smoking behavior; 3) in most high-risk occupations the significant elevations of risk were limited to one or two histologic types, a specificity suggestive of the importance of workplace carcinogen exposure; and 4) both sensitivity and specificity of the search for occupations with lung cancer hazards were greatly increased by use of histologic type rates rather than total lung cancer rates. The epidemiologic differences among histologic types suggest that the lung cancers might be a group of neoplastic diseases which share a major risk factor (smoking) in common but which differ in respect to exposure to other carcinogens. Eventual control of our lung cancer epidemic will require the allocation of much greater resources to documentation of the occupational risks.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Morton WE,Treyve ELdoi
10.1002/ajim.4700030409subject
Has Abstractpub_date
1982-01-01 00:00:00pages
441-57issue
4eissn
0271-3586issn
1097-0274journal_volume
3pub_type
杂志文章abstract：BACKGROUND:The Oak Ridge, Tennessee Y-12 plant has operated as a nuclear materials fabrication plant since the 1940s. Given the work environment, and prior findings that lung cancer mortality was elevated among white male Y-12 workers relative to US white males, we investigated whether lung cancer mortality was associa...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20254
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:There are very few published studies evaluating the impact of safety and health training on injury outcomes in the construction industry. The aim of this study was to assess the impact of the training program on injury rates at a major railway construction project. METHODS:The population consisted of 2,795 ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20770
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:This study examines the prevalence of physician-diagnosed respiratory conditions and mental health symptoms in firefighters and emergency medical service workers up to 9 years after rescue/recovery efforts at the World Trade Center (WTC). METHODS:We analyzed Fire Department of New York (FDNY) physician and ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20993
更新日期：2011-09-01 00:00:00
abstract：:Organic acids and bases are among the most frequently used chemicals in the manufacturing industries. However, the toxicology of only a number of them has been fully characterized, and for fewer still have occupational exposure limits been established. This paper reviews the acute and chronic toxicity data of the orga...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：10.1002/ajim.4700180610
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:There are relatively few studies of large national databases that contain information on working hours and health. The current study involved an analysis of data from a quality of work life (QWL) module developed for the 2002 General Social Survey. This module collected work and health data from a representa...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20388
更新日期：2006-11-01 00:00:00
abstract：BACKGROUND:This study explored economic consequences of work-related injuries using a longitudinal data source. METHODS:Data were from the National Longitudinal Survey of Youth, 1979 cohort (n = 12,686). Short-term consequences were measured when the injury was reported. "Difference-in-differences" approach was applie...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22559
更新日期：2016-02-01 00:00:00
abstract：:Objective measures of exposure furnished by dust monitoring are both costly and time consuming and require a sufficient level of technology. However, they are important in demonstrating exposure-response relationships, in furnishing information necessary to establish environmental control levels, and to assess if inte...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700240406
更新日期：1993-10-01 00:00:00
abstract：OBJECTIVES:Few Canadian data sources allow the examination of disparities by ethnicity, language, or immigrant status in occupational exposures or health outcomes. However, it is possible to document the mechanisms that can create disparities, such as the over-representation of population groups in high-risk jobs. We e...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20845
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:This study sought to identify impacts of compensation system characteristics on doctors in Québec and Ontario. METHODS:(i) Legal analysis; (ii) Qualitative methods applied to documentation and individual and group interviews with doctors (34) and other system participants (31); and (iii) Inter-jurisdictiona...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22651
更新日期：2016-12-01 00:00:00
abstract：:Thirty-eight patients with a diagnosis of malignant mesothelioma participated in a semi-structured interview to evaluate asbestos exposure, acquisition of increased risk information, and retrospective reporting of cognitive and behavioral reactions (particularly smoking behavior) to risk information. Twenty-eight pati...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700040306
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND:Biomass cooking fuel is the main source of indoor air pollution in the majority of households in the developing world. Sri Lanka is an island of about 20 million population with urban, rural, and estate population of 14.6%, 80.0%, and 5.4%, respectively. This study describes biomass fuel use for cooking in S...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.21023
更新日期：2012-12-01 00:00:00
abstract：:Process and office workers at a Swedish paper mill (n = 274) and dairy workers (n = 45) were investigated with questionnaires regarding skin symptoms. In the second part of the study, subjects reporting skin symptoms and a random sample of subjects without symptoms were examined and investigated with patch testing. Pr...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700230506
更新日期：1993-05-01 00:00:00
abstract：BACKGROUND:Migrant and seasonal farmworkers are at risk for occupational illnesses from pesticide exposure, and the effectiveness of pesticide safety regulations has not been evaluated. It is important to learn from farmworker safety experiences to develop effective measures to improve agricultural workplace safety. M...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.1042
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:The occupational lung cancer risk in manufacturing and repair of shoes was studied by pooling of two major case-control studies from Germany. METHODS:Some 4184 incident hospital-based cases of primary lung cancer and 4253 population controls, matched for sex, age, and region of residence were intensively in...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(200006)37:6<575::aid-ajim1
更新日期：2000-06-01 00:00:00
abstract：:This retrospective analysis reviews the clinical experience of a major urban referral hospital with diffuse malignant pleural mesothelioma during the 14-year period from 1973 through 1986. Seventy-five cases of definite or equivocal mesothelioma were identified. There were four cases of primary malignant peritoneal me...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700160405
更新日期：1989-01-01 00:00:00
abstract：:We reviewed 8,502 deaths registered at the Salt River state mortuary, Cape Town (medical examiner records) for an 18-month period (1/1/90-6/30/91). When fatal occupational injuries located from this data source were matched with the records of the occupational safety inspectorate of the Department of Manpower, it was ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700260409
更新日期：1994-10-01 00:00:00
abstract：:Measurement of specific organic compounds in exhaled breath has been used as an indicator of recent exposure to pollutants or as an indicator of the health of an individual. A typical application involves the collection of multiple breaths onto a sorbent cartridge or into an evacuated canister with the use of a relati...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700280110
更新日期：1995-07-01 00:00:00
abstract：:In 1982, White et al published an assessment of quantitative leukemia risk associated with lifetime occupational exposure to benzene. At about the same time, IARC (1982) published estimates of quantitative cancer risk associated with industrial chemicals. Benzene was one of the two chemicals selected by IARC for its r...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：10.1002/ajim.4700070507
更新日期：1985-01-01 00:00:00
abstract：:This report describes the reanalysis of a cross-sectional study of asthma in a large cohort of autoworkers with exposure to metalworking fluids (MWF). There is strong evidence from case reports, clinical studies, and medical surveillance data that exposure to MWF can cause asthma, yet no association was found in the o...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199706)31:6<671::aid-ajim1
更新日期：1997-06-01 00:00:00
abstract：BACKGROUND:The Denver International Airport construction project provided a rare opportunity to identify risk factors for injury on a large construction project for which 769 contractors were hired to complete 2,843 construction contracts. Workers' compensation claims and payroll data for individual contracts were reco...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199808)34:2<113::aid-ajim3
更新日期：1998-08-01 00:00:00
abstract：:This case-referent study assesses occupational risk factors associated with lung cancer, utilizing colon and rectum cancer referents. Complete occupational and tobacco use histories were obtained by telephone interview for 5,935 incident lung cancer cases and 3,956 incident colon and rectum cancer referents. The analy...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700190510
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Farmworkers who delay treatment after workplace injuries may increase injury severity and experience longer recovery times. To understand why farmworkers delay treatment we employed a mixed-methods analysis of 393 farmworker injury narratives from the National Agricultural Workers Survey (NAWS). METHODS:Fir...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22380
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:Occupational exposure to vinyl chloride monomer (VCM) has been established as a cause of hepatocellular carcinoma (HCC) and liver angiosarcoma (ASL). However, some controversy remains due to conflicting results on liver cirrhosis, and to evidence on HCC based on few confirmed cases. The aim of the study is t...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22922
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:This study investigated the relationship between weekly working hours and the occurrence of cerebro-cardiovascular diseases using a case-crossover study design. METHODS:We investigated average working hours during the 7 days before the onset of illness (hazard period) and average weekly working hours betwee...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22688
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:The oncogene product EGF-receptor (EGF-R), the tumor suppressor gene product p53, and anti-p53 antibodies are detectable in serum of certain cancer patients. Increased levels of some of these products were reported in lung cancer patients after occupational asbestos exposure, after exposure to polycyclic aro...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,多中心研究
doi：10.1002/(sici)1097-0274(199912)36:6<602::aid-ajim2
更新日期：1999-12-01 00:00:00
abstract：BACKGROUND:Previous epidemiological studies investigating modification of organophosphate (OP) neurotoxicity by xenobiotic metabolizing enzymes (XMEs) polymorphisms have produced inconsistent results. METHODS:A cross-sectional study of 301 emerging farmers was conducted. Neurotoxicity testing included forward and back...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22790
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:A program of medical evaluation for former Savannah River Site (SRS) workers at health effects due to exposures to hazardous or radioactive agents was conducted. METHODS:This study includes data from 1,368 participants aged 45 years or older who were assessed regarding work-history and exposures to industri...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20224
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to evaluate cancer incidence in the membership a largely Hispanic farmworker labor union in California, the United Farmworkers of America (UFW) and to examine cancer-site specific distributions as well as histology and stage of cancer at diagnosis in this group. METHODS:An elec...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.1125
更新日期：2001-11-01 00:00:00
abstract：:While blood lead concentration has been inversely associated with indicators of reproductive health in occupationally exposed male workers, the utility of lead concentration in semen as an indicator of lead exposure to the male reproductive system has not been fully explored. Blood and semen lead concentrations from 8...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199811)34:4<464::aid-ajim2
更新日期：1998-11-01 00:00:00
abstract：BACKGROUND:Many authorities are concerned about the rising use and the potential overuse of opioid pain medications. A study of opioid prevalence and dosage in Ohio's workers' compensation (WC) system was conducted, with comparisons made to opioid use in other WC and non-WC settings. METHODS:Systematic literature revi...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：10.1002/ajim.21021
更新日期：2012-04-01 00:00:00
