Cognitive effects of chronic exposure to lead and solvents.

Abstract:

BACKGROUND:Occupational exposure to lead and solvents has declined steadily over the past 20 years, however, construction workers continue to be exposed to these neurotoxicants. The purpose of this study was to investigate the cognitive effects of chronic occupational exposure to lead and solvents. METHOD:Based on K-XRF of tibial bone lead and occupational history of solvent exposure, subjects were classified into four exposure groups: lead (N = 40), solvent (N = 39), lead/solvent (N = 45), and control (N = 33). All subjects completed tests to assess concentration, motor skills, memory, and mood. RESULTS:Relative to controls, the lead, solvent, and lead/solvent groups performed significantly more poorly on a test of verbal memory, while the lead and lead/solvent groups were slower than the solvent and control groups on a task of processing speed. Bone lead was a significant predictor of information processing speed and latency of response while solvent exposure was a significant predictor of verbal learning and memory. CONCLUSIONS:Bone lead was associated with slower speed of processing while exposure to lead and/or solvents reduced efficiency of verbal learning.

journal_name

Am J Ind Med

authors

Fiedler N,Weisel C,Lynch R,Kelly-McNeil K,Wedeen R,Jones K,Udasin I,Ohman-Strickland P,Gochfeld M

doi

10.1002/ajim.10287

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

413-23

issue

4

eissn

0271-3586

issn

1097-0274

journal_volume

44

pub_type

杂志文章
  • Relationship of respiratory health status to grain dust in a Witwatersrand grain mill: comparison of workers' exposure assessments with industrial hygiene survey findings.

    abstract::Objective measures of exposure furnished by dust monitoring are both costly and time consuming and require a sufficient level of technology. However, they are important in demonstrating exposure-response relationships, in furnishing information necessary to establish environmental control levels, and to assess if inte...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700240406

    authors: Fonn S,Groeneveld HT,deBeer M,Becklake MR

    更新日期:1993-10-01 00:00:00

  • Serial evaluations at an indium-tin oxide production facility.

    abstract:BACKGROUND:We evaluated the effectiveness of workplace changes to prevent indium lung disease, using 2002-2010 surveillance data collected by an indium-tin oxide production facility. METHODS:We assessed pulmonary function using lower limits of normal. Blood indium concentration and personal air sampling data were used...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22125

    authors: Cummings KJ,Suarthana E,Edwards N,Liang X,Stanton ML,Day GA,Saito R,Kreiss K

    更新日期:2013-03-01 00:00:00

  • Increasing capacity for environmental engineering in Salta, Argentina.

    abstract:BACKGROUND:The Fogarty International Center (FIC) of the United States National Institutes of Health includes the International Training and Research in Environmental and Occupational Health (ITREOH) Program. The "International Training Program in Environmental Toxicology and Public Health" Center, funded in 2002 is ba...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22044

    authors: Rajal VB,Cid AG,Cruz MC,Poma HR,Cacciabue DG,Romano N,Moraga NB,Last JA

    更新日期:2013-01-01 00:00:00

  • Life-span carcinogenicity studies on Sprague-Dawley rats exposed to γ-radiation: design of the project and report on the tumor occurrence after post-natal radiation exposure (6 weeks of age) delivered in a single acute exposure.

    abstract:BACKGROUND:Experimental long-term carcinogenicity bioassays conducted on rats and mice proved that ionizing radiation can induce a variety of tumor types. However few studies have been conducted on rats. METHODS:This report deals with the effects of γ-radiation in groups of 416-1,051 6-weeks old Sprague-Dawley rats ex...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22391

    authors: Soffritti M,Tibaldi E,Bua L,Padovani M,Falcioni L,Lauriola M,Manservigi M,Manservisi F,Belpoggi F

    更新日期:2015-01-01 00:00:00

  • Descriptive evaluation of methods for identifying work-related emergency department injury visits.

    abstract:BACKGROUND:Use of worker's compensation (WC) as payer underestimates work-related (WR) injuries. We evaluated three methods to identify WR injuries: WC as payer, ICD-9-CM work-status codes E000.0/E000.1, and other ICD-9-CM external cause codes. METHODS:We identified injury-related emergency department visits from Nort...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22984

    authors: Harduar Morano L,Richardson D,Proescholdbell S

    更新日期:2019-07-01 00:00:00

  • Detection of occult lung impairment in welders by induced sputum particles and breath oxidation.

    abstract:BACKGROUND:We evaluated particulate matter in combined induced sputum (IS) and oxidation in exhaled breath condensate (EBC) to test whether underlying inflammatory changes are present in asymptomatic welders. METHODS:Thirty welders from the Israel Defense Forces exposed to aluminum/iron (Group 1) or to cadmium/chromiu...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20586

    authors: Fireman E,Lerman Y,Stark M,Schwartz Y,Ganor E,Grinberg N,Frimer R,Landau DA,Zilberberg M,Barenboim E,Jacovovitz R

    更新日期:2008-07-01 00:00:00

  • Decreases in postural change in finger blood flow in ceramic painters chronically exposed to low level lead.

    abstract::To elucidate the effect of low level lead (Pb) exposure on somatic and autonomic peripheral nerve functions in ceramic painters, 58 males and 70 females, aged 29-75 years (mean 53.3 years), with lead concentrations in blood (Pb-B) ranging from 2.1 to 69.5 micrograms/dl (geometric mean 13.3 micrograms/dl), were examine...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0274(199605)29:5<547::AID-AJIM1

    authors: Ishida M,Ishizaki M,Yamada Y

    更新日期:1996-05-01 00:00:00

  • Estimation of the global burden of disease attributable to contaminated sharps injuries among health-care workers.

    abstract:BACKGROUND:The global burden of hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) infection due to percutaneous injuries among health care workers (HCWs) is estimated. METHODS:The incidence of infections attributable to percutaneous injuries in 14 geographical regions on the basis of the pro...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20230

    authors: Prüss-Ustün A,Rapiti E,Hutin Y

    更新日期:2005-12-01 00:00:00

  • Exposures to silica mixed dust and cohort mortality study in tin mines: exposure-response analysis and risk assessment of lung cancer.

    abstract:BACKGROUND:Mineral dusts that contain crystalline silica have been associated directly or indirectly with the development of pneumoconiosis or silicosis, non-malignant respiratory diseases, lung cancer, and other diseases. The health impacts on workers with silica mixed dust exposure in tin mines and dose-response rela...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20248

    authors: Chen W,Yang J,Chen J,Bruch J

    更新日期:2006-02-01 00:00:00

  • Occupational exposure to crystalline silica: estimating the number of workers potentially at high risk in Italy.

    abstract:BACKGROUND:Occupational exposure to free silica is widespread in several economic sectors and is well known to cause silicosis. This study was designed to establish a database of enterprises and workers in industrial sectors involving silica exposure in Italy and to estimate the number of workers potentially at high ri...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20619

    authors: Scarselli A,Binazzi A,Marinaccio A

    更新日期:2008-12-01 00:00:00

  • The health of California's immigrant hired farmworkers.

    abstract:BACKGROUND:Hispanic immigrant workers dominate California's hired farm workforce. Little is known about their health status; even less is known about those lacking employment authorization. METHODS:The California Agricultural Workers Health Survey (CAWHS) was a statewide cross-sectional household survey conducted in 1...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20796

    authors: Villarejo D,McCurdy SA,Bade B,Samuels S,Lighthall D,Williams D 3rd

    更新日期:2010-04-01 00:00:00

  • Comparison of fatal and severe nonfatal traumatic work-related injuries in Washington state.

    abstract:OBJECTIVE:To compare fatal and hospitalized nonfatal work-related traumatic injuries by occupation and cause. METHODS:Fatal and hospitalized nonfatal injuries occurring from 1991-1995 were identified from Washington State workers' compensation claims data. Nonfatal injuries were classified as severe if they had at lea...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199908)36:2<317::aid-ajim1

    authors: Alexander BH,Franklin GM,Fulton-Kehoe D

    更新日期:1999-08-01 00:00:00

  • A proportionate mortality study of granite cutters.

    abstract::Several recent studies (animal and human) have suggested an association between lung cancer and silica exposure. To test the hypothesis, we have studied death benefit records of 1,905 members of the Granite Cutters Union. A proportionate mortality analysis (PMR) was conducted, using U.S. deaths as a comparison populat...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700090210

    authors: Steenland K,Beaumont J

    更新日期:1986-01-01 00:00:00

  • Risk factors for systemic illnesses following agricultural exposures to restricted organophosphates in California, 1984-1988.

    abstract::Organophosphate (OP)-related systemic illnesses reported to the Worker Health and Safety (WH&S) Branch, and restricted OP-related agricultural use data reported to the Information Services Branch at the California Department of Food and Agriculture (CDFA) (now CAL-EPA) during 1984-1988 were used to assess factors asso...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199705)31:5<572::aid-ajim1

    authors: Weinbaum Z,Schenker MB,Gold EB,Samuels SJ,O'Malley MA

    更新日期:1997-05-01 00:00:00

  • Issues in notification: reflections of a public health worker.

    abstract::The objectives of notification are to inform individuals of research results so that they can make informed choices regarding health care and risk reduction behaviors, and to inform workers and employers of results and recommendations in order to take actions to improve workplace health and safety. Many questions conf...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700230109

    authors: Rudolph L

    更新日期:1993-01-01 00:00:00

  • Pulmonary abnormalities associated with occupational exposures at the Savannah River Site.

    abstract:BACKGROUND:A program of medical evaluation for former Savannah River Site (SRS) workers at health effects due to exposures to hazardous or radioactive agents was conducted. METHODS:This study includes data from 1,368 participants aged 45 years or older who were assessed regarding work-history and exposures to industri...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20224

    authors: Makie T,Adcock D,Lackland DT,Hoel DG

    更新日期:2005-11-01 00:00:00

  • Acute traumatic injuries in underground bituminous coal miners.

    abstract::Using injury information from the 1986 Mine Safety and Health Administration database, and demographic information from a 1986 sample survey of the miner population, acute traumatic injury rates for male workers in underground bituminous coal mines were computed by age, current job experience, and total mine work expe...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700230304

    authors: Lee T,Anderson C,Kraus JF

    更新日期:1993-03-01 00:00:00

  • Mortality comparisons of chemical workers hired before, during, and after World War II (1941-1945).

    abstract::Cause-specific mortality was evaluated by period of hire for 37,682 male chemical workers in order to test the hypothesis that employees hired during World War II (1941-1945) were at increased risk for selected causes of death. One recent study of refinery workers reported that those hired during the war years had exp...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700150308

    authors: Bond GG,Lipps TE,Cook RR

    更新日期:1989-01-01 00:00:00

  • Injuries and fatalities to U.S. farmers and farm workers 55 years and older.

    abstract:BACKGROUND:Previous studies have shown that older farmers and farm workers have been identified at high risk for farm fatalities, most notably involving tractor overturns. Older farmers also incur more severe non-fatal injuries. METHODS:Data from two national surveillance systems are presented to describe fatal and no...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20661

    authors: Myers JR,Layne LA,Marsh SM

    更新日期:2009-03-01 00:00:00

  • Lead exposure in ironworkers.

    abstract::In adults, lead toxicity is most commonly caused by occupation in a lead industry. Whereas lead toxicity has been described in workers who are involved in bridge rehabilitation, as of this date there has been no systematic evaluation published regarding the conditions responsible for lead toxicity in ironworkers. This...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199711)32:5<540::aid-ajim1

    authors: Forst L,Persky V,Freels S,Williams R,Conroy L

    更新日期:1997-11-01 00:00:00

  • Pregnancy abnormalities among personnel at a virological laboratory.

    abstract::Observations on an increased spontaneous abortion rate initiated a study among personnel working at a laboratory for diagnostic virology. Personnel at a bacteriological laboratory and at another virological laboratory served as controls. Seventy-seven female employees at the laboratory for virology were interviewed, a...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700010203

    authors: Axelsson G,Jeansson S,Rylander R,Unander M

    更新日期:1980-01-01 00:00:00

  • Incidence of work and non-work related disability claims in Brazil.

    abstract:BACKGROUND:Sickness benefit claims are an important economic burden to society. This study aims to determine the incidence of sickness benefit claims in Brazil in 2008, exploring the role of economic activity. METHODS:Population-based study on sickness claims lasting longer than 15 days of sickness absence granted to ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20974

    authors: Barbosa-Branco A,Souza WR,Steenstra IA

    更新日期:2011-11-01 00:00:00

  • Impact of California's safe patient handling legislation on musculoskeletal injury prevention among nurses.

    abstract:BACKGROUND:This study evaluated the impact of California's safe patient handling (SPH) legislation on musculoskeletal injury prevention among hospital nurses. METHODS:Two serial cross-sectional surveys were conducted using postal and online questionnaires in statewide random samples of California registered nurses in ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22923

    authors: Lee SJ,Lee JH,Harrison R

    更新日期:2019-01-01 00:00:00

  • Pulmonary and systemic toxicity following exposure to nickel nanoparticles.

    abstract::Nanoparticles are being used in ever increasing numbers in a range of industrial and medical products. Questions surrounding their potential to cause toxic effects in humans have been raised. Although animal experiments predict that nanoparticles are more toxic than their larger counterparts there are few descriptions...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20855

    authors: Phillips JI,Green FY,Davies JC,Murray J

    更新日期:2010-08-01 00:00:00

  • A cohort mortality study of construction workers.

    abstract::This report presents a mortality study among the 17,344 members of the Construction Workers' Health Insurance Society of Mie Prefecture in Japan. The study period was between 1973 and 1993. During this period, 480 members died. Age-specific mortality rates of Mie Prefecture were used as comparison standards. Significa...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199707)32:1<35::aid-ajim5>

    authors: Sun J,Shibata E,Hisanaga N,Kamijima M,Ichihara G,Huang J,Toida M,Takeuchi Y

    更新日期:1997-07-01 00:00:00

  • Contribution of biological markers to occupational health.

    abstract::Occupational diseases are now being assessed at the cellular and molecular levels; this presents new opportunities for prevention and control [Calleman et al., 1978; Ong et al., 1987; Stejskal et al., 1989; Welch and Cullen, 1988; Garry et al., 1989]. The key to these opportunities is the ability to detect biological ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章,评审

    doi:10.1002/ajim.4700200402

    authors: Schulte PA

    更新日期:1991-01-01 00:00:00

  • Statistical model for prediction of retrospective exposure to ethylene oxide in an occupational mortality study.

    abstract::Since direct measures of individual exposure seldom exist for the entire period of an occupational mortality study, retrospective exposure estimates are necessary. This is often done in a subjective manner involving a consensus of opinion from a panel of epidemiologists and industrial hygienists. An alternative method...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700250607

    authors: Hornung RW,Greife AL,Stayner LT,Steenland NK,Herrick RF,Elliott LJ,Ringenburg VL,Morawetz J

    更新日期:1994-06-01 00:00:00

  • Parkinson's disease and occupation: differences in associations by case identification method suggest referral bias.

    abstract:METHODS:We used a population-based sample of 403 Parkinson's disease cases and 405 controls to examine risks by occupation. Results were compared to a previous clinic-based analysis. RESULTS:With censoring of jobs held within 10 years of diagnosis, the following had significantly or strongly increased risks: social sc...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22272

    authors: Teschke K,Marion SA,Tsui JK,Shen H,Rugbjerg K,Harris MA

    更新日期:2014-02-01 00:00:00

  • Work safety climate and safety practices among immigrant Latino residential construction workers.

    abstract:BACKGROUND:Latino residential construction workers experience high rates of occupational fatality and injury. Work safety climate is an especially important consideration for improving the safety of these immigrant workers. This analysis describes work safety climate among Latino residential construction workers, delin...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22058

    authors: Arcury TA,Mills T,Marín AJ,Summers P,Quandt SA,Rushing J,Lang W,Grzywacz JG

    更新日期:2012-08-01 00:00:00

  • Non-fatal farm injuries on 117 eastern Ontario beef and dairy farms: a one-year study.

    abstract::A one-year prospective survey was conducted to study the incidence of and potential risk factors for farm-related injuries in Eastern Ontario. One hundred and seventeen dairy and beef farms were surveyed using a personal interview. Information was collected on demographic characteristics of the farm owners, workers, a...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700210503

    authors: Brison RJ,Pickett CW

    更新日期:1992-01-01 00:00:00