Abstract:
:Nanoparticles are being used in ever increasing numbers in a range of industrial and medical products. Questions surrounding their potential to cause toxic effects in humans have been raised. Although animal experiments predict that nanoparticles are more toxic than their larger counterparts there are few descriptions in the literature of human exposure. A case described in 1994 has been re-examined from a pathology perspective. The subject, a 38-year-old previously healthy male, inhaled nanoparticles of nickel while spraying nickel onto bushes for turbine bearings using a metal arc process. He died 13 days after being exposed and the cause of death at autopsy was adult respiratory distress syndrome (ARDS). Nickel particles <25 nm in diameter were identified in lung macrophages using transmission electron microscopy. High levels of nickel were measured in his urine and his kidneys showed evidence of acute tubular necrosis.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Phillips JI,Green FY,Davies JC,Murray Jdoi
10.1002/ajim.20855subject
Has Abstractpub_date
2010-08-01 00:00:00pages
763-7issue
8eissn
0271-3586issn
1097-0274journal_volume
53pub_type
杂志文章abstract:BACKGROUND:Correctional Officers (COs) have among the highest injury rates and poorest health of all the public safety occupations. The HITEC-2 (Health Improvement Through Employee Control-2) study uses Participatory Action Research (PAR) to design and implement interventions to improve health and safety of COs. METHO...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22593
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:The roles of age, length of service and job in various work-related injury types are unknown and deserve investigations among female workers. This study assessed their roles in the occurrence of injury. METHODS:Three-year prospective study of all 22,952 permanently employed women at the French national rail...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22259
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Approximately 25-30% of nursing personnel experience knee pain (KP). We sought to identify physical and psychosocial work exposures, and personal factors related to prevalent, incident, and persistent KP 5-8 years after safe resident handing program (SRHP) implementation in nursing homes. METHODS:Health and ex...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22902
更新日期:2018-10-01 00:00:00
abstract::We reviewed 8,502 deaths registered at the Salt River state mortuary, Cape Town (medical examiner records) for an 18-month period (1/1/90-6/30/91). When fatal occupational injuries located from this data source were matched with the records of the occupational safety inspectorate of the Department of Manpower, it was ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260409
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVE:To assess whether unionization prevents deterioration in self-reported health and depressive symptoms in late career transitions. METHODS:Data come from the Health and Retirement Study (N = 6475). The change in self-perceived health (SPH) and depressive symptoms (CESD) between wave 11 and wave 12 is explaine...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22877
更新日期:2018-06-28 00:00:00
abstract::The evidence from animal studies indicates that organic extracts of diesel particulate are mutagenic and carcinogenic. Of four animal inhalation studies, two have been positive and two have been largely negative. The most recent data indicate that inhalation studies may be positive only with high doses of exhaust. Hum...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700100208
更新日期:1986-01-01 00:00:00
abstract::To determine the nature of respiratory functional impairment caused by asbestos-induced visceral pleural fibrosis (VPF) and to discover which pulmonary physiological variable best reveals it, we examined 59 asbestos-exposed construction workers having asbestos-related changes on chest radiographs. Computed tomography ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280306
更新日期:1995-09-01 00:00:00
abstract::The National Research Council's report "Protecting Youth at Work" addresses the health and safety consequences of work by youth in the United States. The report finds that a higher proportion of U.S. youth work than in any other developed nation and that as much as 80% of youth will have worked during their high schoo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199911)36:5<579::aid-ajim1
更新日期:1999-11-01 00:00:00
abstract::A death certificate mortality odds ratio study of seven cancer sites was conducted by using 1979-1984 data on Illinois deaths in white and black males. Cancer sites selected include stomach, pancreas, lung, prostate, bladder, brain, and non-Hodgkin's lymphomas. This surveillance study was undertaken to detect occupati...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700150609
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Studies comparing different forms of asbestos are rare, and limited by the failure to compare results with unexposed populations. We compare autoimmune responses among former workers and residents of the crocidolite mining and milling town of Wittenoom, Western Australia, with an unexposed population. METHO...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22863
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Hospital workers are a diverse population with high rates of musculoskeletal disorders (MSDs). The risk of MSD leading to workers' compensation (WC) claims is likely to show a gradient by socioeconomic status (SES) that may be partly explained by working conditions. METHODS:A single community hospital provi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20702
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate cancer incidence in the membership a largely Hispanic farmworker labor union in California, the United Farmworkers of America (UFW) and to examine cancer-site specific distributions as well as histology and stage of cancer at diagnosis in this group. METHODS:An elec...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1125
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Correct identification of wayside signal colors is critical for safe operation of railway equipment. However, evaluating color discrimination using just a screening test may not be occupationally relevant. METHODS:A lantern test (CNLAN) was designed to provide a functional assessment of color discrimination...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/1097-0274(200012)38:6<681::aid-ajim8>3.0.c
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:Many newly constructed green buildings (GB) are certified using the United States Green Building Council (USGBC) Leadership in Energy and Environmental Design (LEED) rating system for new construction and major renovation which focuses on architectural and mechanical design to conserve energy, reduce environ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22166
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Production of asbestos-cement products in Brazil started in the 1940s, peaked in the 60-70s and is still an active industry. This study was designed to assess the non-malignant effects of asbestos exposure in the asbestos-cement industry in Brazil. METHODS:A group of 828 former asbestos-cement workers enrol...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1095
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Job-exposure matrices (JEM) are used for exposure assessment in occupational studies, but they can involve errors. We assessed agreement between the Nordic Occupational Cancer Studies JEM (NOCCA-JEM) and aggregate and individual dose estimates for cosmic radiation exposure among Finnish airline personnel. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22705
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:The etiology of breast cancer is not well understood and the role of occupational exposures in breast carcinogenesis is still uncertain. METHODS:The population-based case-control study included 2,386 incident breast cancer cases diagnosed in 2000-2003, and 2,502 controls. Lifetime occupational histories and...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20420
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVES:Few Canadian data sources allow the examination of disparities by ethnicity, language, or immigrant status in occupational exposures or health outcomes. However, it is possible to document the mechanisms that can create disparities, such as the over-representation of population groups in high-risk jobs. We e...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20845
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Farmworkers who delay treatment after workplace injuries may increase injury severity and experience longer recovery times. To understand why farmworkers delay treatment we employed a mixed-methods analysis of 393 farmworker injury narratives from the National Agricultural Workers Survey (NAWS). METHODS:Fir...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22380
更新日期:2015-02-01 00:00:00
abstract::Asbestos has been widely used in the refinery and petrochemical sector. Mesothelioma has occurred among maintenance employees, and it was hypothesized that mesothelioma is a marker for exposures which might increase lung cancer risk. A death certificate-based case-control study of mesothelioma and lung cancer from 198...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199611)30:5<610::AID-AJIM9
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Acoustic neuroma is the intracranial tumor subtype showing the highest relative risk in relation to ionizing radiation but other environmental risk factors are largely unknown. This study was performed to investigate the effect of power frequency magnetic fields. METHOD:A total of 793 cases between 1987 and...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20251
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:The mortality experience of iron and steel workers from modern plants in developing countries has not been extensively described. METHODS:Mortality at two Korean iron and steel manufacturing complexes was analyzed using Poisson regression methods with both direct and indirect standardization. Work histories...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20197
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Use of worker's compensation (WC) as payer underestimates work-related (WR) injuries. We evaluated three methods to identify WR injuries: WC as payer, ICD-9-CM work-status codes E000.0/E000.1, and other ICD-9-CM external cause codes. METHODS:We identified injury-related emergency department visits from Nort...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22984
更新日期:2019-07-01 00:00:00
abstract:METHODS:We used a population-based sample of 403 Parkinson's disease cases and 405 controls to examine risks by occupation. Results were compared to a previous clinic-based analysis. RESULTS:With censoring of jobs held within 10 years of diagnosis, the following had significantly or strongly increased risks: social sc...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22272
更新日期:2014-02-01 00:00:00
abstract::The objective of this study was to examine the endocrine profiles of a group of male workers chronically exposed to trichloroethylene (TCE) in an electronics factory. A total of 124 workers participated in a preliminary study, for which 85 satisfied the selection criteria and were recruited to take part in a more deta...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199709)32:3<217::aid-ajim6
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Although increased attention has been focused on the relationship between occupational health and productivity, solid scientific data on this topic are sparse. The purpose of the present case study was to assess the relationship between productivity and work environment in a storage building. MATERIALS AND ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10119
更新日期:2002-10-01 00:00:00
abstract::Substances referred to as formaldehyde releasers were identified on review of the literature. Information on product categories and typical concentrations for chemical products containing formaldehyde and formaldehyde releasers was obtained from the Danish Product Register Data Base (PROBAS). As of February 1992, 62,0...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240505
更新日期:1993-11-01 00:00:00
abstract::The mortality profile of female nurses and teachers in British Columbia (BC) was examined using age-standardized proportional mortality ratios (PMRs) calculated for the period 1950-1984. Lowered overall mortality among nurses was seen for degenerative heart disease and for cerebrovascular accidents. Significantly elev...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260111
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:The etiologic role of biomechanical factors for low back injury (LBI) needs to be confirmed in prospective studies that control for psychosocial factors. METHODS:Complete baseline information on 1,233 vehicle operators was gathered during medical examinations and by questionnaire. First LBI during 7.5 years...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20094
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Work-related asthma (WRA) is the most common work-associated respiratory disease in developed countries. METHOD:We report shark cartilage dust as a new potential cause of occupational asthma (OA) in the context of other fatal OA case reports. RESULTS:A 38-year-old white male worked for 8 years in a facilit...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.10088
更新日期:2002-07-01 00:00:00