Abstract:
BACKGROUND:Experimental long-term carcinogenicity bioassays conducted on rats and mice proved that ionizing radiation can induce a variety of tumor types. However few studies have been conducted on rats. METHODS:This report deals with the effects of γ-radiation in groups of 416-1,051 6-weeks old Sprague-Dawley rats exposed to 0, 0.1, 1, or 3 Gy of γ-radiation delivered in a single acute exposure. The experiment lasted for the animals' lifespan and all were necropsied and underwent full histopathological evaluation. RESULTS:The results confirm the dose-related carcinogenic effects of γ-radiation for several organs and tissues. Moreover they indicate that exposure to 0.1 Gy induces a statistically significant increased incidence in Zymbal gland carcinomas and pancreas islet cell carcinomas in females. CONCLUSIONS:Our data show that exposure to γ-radiation induces carcinogenic effects at all tested doses.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Soffritti M,Tibaldi E,Bua L,Padovani M,Falcioni L,Lauriola M,Manservigi M,Manservisi F,Belpoggi Fdoi
10.1002/ajim.22391subject
Has Abstractpub_date
2015-01-01 00:00:00pages
46-60issue
1eissn
0271-3586issn
1097-0274journal_volume
58pub_type
杂志文章abstract:BACKGROUND:Knowledge on intrapulmonary lymph nodes (IPLNs) is still limited. Progress in imaging techniques has enabled easier, more frequent visualization of IPLNs so that a more comprehensive understanding of these nodes is necessary. METHODS:Microscopic slides of lung tissue from 2,337 dust-exposed South African mi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20436
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Use of surrogate responders often needs to be considered in case-control studies with a high case fatality. METHODS:Agreement between 98 colon cancer patients and their closest relative was expressed as a percentage of the exact agreement and by Kappa coefficients and intra-class correlation coefficients. ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10266
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:This study explored perspectives of Northeast commercial lobstermen regarding the use of personal flotation devices (PFDs). Researchers sought to identify factors contributing to low PFD use, and motivators that could lead to increased use of PFDs. METHODS:This qualitative research (n = 72) included 25 comm...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22537
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:The prevalence of violence to first responders is reported in ranges of approximately 40% to 90%. Pennsylvania has a felonious assault statute to address such violence, but the prosecutorial process has been noted to cause first-responder dissatisfaction. METHODS:An exploratory qualitative study using ind...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23036
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Occupational bladder cancer mortality among minority racial/ethnic groups is not well described compared to occupational bladder cancer mortality among non-minority males in the United States. METHODS:Race/ethnicity- and sex-specific bladder cancer mortality (1985-1992) of workers employed in 21 states was ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/1097-0274(200007)38:1<90::aid-ajim10>3.0.c
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Hospital workers are a diverse population with high rates of musculoskeletal disorders (MSDs). The risk of MSD leading to workers' compensation (WC) claims is likely to show a gradient by socioeconomic status (SES) that may be partly explained by working conditions. METHODS:A single community hospital provi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20702
更新日期:2009-07-01 00:00:00
abstract::Semen analysis has proven useful in the clinical diagnosis of infertility and is the most widely used method of monitoring the effects of occupational exposure on male fertility. Collection and analysis of semen samples in a field setting, however, require a highly motivated population and excellent technical resource...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700200209
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Autopsied lungs from 29 hard rock miners were investigated to determine the relationship of the dust content to pathology, radiology, and occupational exposure. METHODS:Each lung was divided horizontally into three sections. Pathological and radiological studies and chemical analyses were carried out on sam...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20589
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Use of worker's compensation (WC) as payer underestimates work-related (WR) injuries. We evaluated three methods to identify WR injuries: WC as payer, ICD-9-CM work-status codes E000.0/E000.1, and other ICD-9-CM external cause codes. METHODS:We identified injury-related emergency department visits from Nort...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22984
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Asbestos fibers are known to accumulate in lung parenchyma and thoracic lymph nodes, but their presence and translocation into the extrapulmonary tissues need clarification. We assessed the presence of asbestos in the para-aortic (PA) and mesenteric (ME) lymph nodes. METHODS:PA and ME lymph nodes and lung t...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20694
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:In recent decades, the use of artificial nails including methacrylates (MAs) has increased. This study presents the first two clinical cases of occupational asthma (OA) caused by sculptured nails containing MAs. METHODS:In both cases, OA was diagnosed on the basis of a work simulation test combined with the...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20633
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:From 1970 through 1997, 17 intracranial neoplasms were identified among 6,800 employees of a petrochemical research facility. This investigation describes the case-series. METHODS:The intracranial neoplasms were identified by self reports and record linkages, and were confirmed by medical records and a path...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199910)36:4<450::aid-ajim6
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:This study compared floor laying using new working methods involving standing up, to the traditional methods involving working on one's knees. METHODS:The study group, 216 subjects, completed a training class in the use of the new floor-laying methods, and received free tools and advice in their use. The co...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20808
更新日期:2010-06-01 00:00:00
abstract::Currently available computerized hospital records from four hospitals in Southwest Oregon were utilized for occupational health surveillance by administering brief occupational questionnaires to hospitalized male patients. Patients with occupational exposure to the lumber and wood products industries showed statistica...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700040605
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Community Participatory Approach to Measuring Farmworker Pesticide Exposure, PACE3, used a longitudinal design to document pesticide biomarkers among farmworkers. This article presents an overview of PACE3 and provides a descriptive analysis of participant characteristics and one set of pesticide biomarkers,...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20703
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Radiographic shadows of coal workers' pneumoconiosis (CWP) are commonly described as predominantly in the upper lung zones. METHODS:We evaluated the lung distribution of small opacities on surveillance chest radiographs (CXRs) taken between 1981 and 2010 among 2,467 underground US coal miners. All had evide...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22049
更新日期:2012-09-01 00:00:00
abstract::In order to determine the possible actual exposure to benzene in the shoe industry from industrially used solvents, glues, and paints containing benzene as a nondeclared constituent, phenol in urine and benzene in blood, as indices of internal exposure to benzene, were measured in workers (N = 33). Since toluene, in c...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120507
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:We evaluated the effectiveness of workplace changes to prevent indium lung disease, using 2002-2010 surveillance data collected by an indium-tin oxide production facility. METHODS:We assessed pulmonary function using lower limits of normal. Blood indium concentration and personal air sampling data were used...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22125
更新日期:2013-03-01 00:00:00
abstract::Roll-over protective structures (ROPS) on farm tractors could significantly reduce the rate of fatal occupational injury on farms, but comparatively few tractors have them. Many of the policy discussions have focused on trying to identify the percentage of tractors that do not have ROPS, even though such a focus proba...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199610)30:4<447::AID-AJIM1
更新日期:1996-10-01 00:00:00
abstract::Asbestos has been widely used in the refinery and petrochemical sector. Mesothelioma has occurred among maintenance employees, and it was hypothesized that mesothelioma is a marker for exposures which might increase lung cancer risk. A death certificate-based case-control study of mesothelioma and lung cancer from 198...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199611)30:5<610::AID-AJIM9
更新日期:1996-11-01 00:00:00
abstract::Several recent studies (animal and human) have suggested an association between lung cancer and silica exposure. To test the hypothesis, we have studied death benefit records of 1,905 members of the Granite Cutters Union. A proportionate mortality analysis (PMR) was conducted, using U.S. deaths as a comparison populat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700090210
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Cattle are responsible for more injuries and fatalities than any farm animal, and cattle-related nonfatal injuries are some of the costliest, requiring more time off work than other injuries. Though research has improved our understanding of cattle behavior, developed low-stress handling practices, and deter...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23043
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The occupational lung cancer risk in manufacturing and repair of shoes was studied by pooling of two major case-control studies from Germany. METHODS:Some 4184 incident hospital-based cases of primary lung cancer and 4253 population controls, matched for sex, age, and region of residence were intensively in...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(200006)37:6<575::aid-ajim1
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Migrant and seasonal farmworkers are at risk for occupational illnesses from pesticide exposure, and the effectiveness of pesticide safety regulations has not been evaluated. It is important to learn from farmworker safety experiences to develop effective measures to improve agricultural workplace safety. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1042
更新日期:2001-05-01 00:00:00
abstract::Pathologists eligible for inclusion in the study were identified from the membership lists of the Royal College of Pathologists from 1974 to 1987, establishing a population of 4,512 members. Overall mortality was lower among the study group compared with the general population of England and Wales, although there were...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700200108
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The Limulus amebocyte lysate (LAL) assay may underestimate endotoxins because only soluble endotoxins are determined. The solubility of endotoxins was, therefore, studied in two species of Gram-negative bacteria. METHODS:Cultures were grown in serum broth, cells were harvested by centrifugation and washed i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20089
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:An epidemic of asbestos-related diseases is ongoing worldwide. Mortality from malignant pleural neoplasms in Italy was analyzed, to estimate the health impact of asbestos at national and local level. METHODS:Mortality from ICD-9 code 163 was considered, in the time-window 1995-2002, using National Bureau of...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.21015
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate cancer incidence in the membership a largely Hispanic farmworker labor union in California, the United Farmworkers of America (UFW) and to examine cancer-site specific distributions as well as histology and stage of cancer at diagnosis in this group. METHODS:An elec...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1125
更新日期:2001-11-01 00:00:00
abstract::Potential exposures to extremely low frequency (ELF) magnetic fields were investigated in response to worker concerns about an apparent increased spontaneous abortion risk in a payroll office environment. Concern in this office centered on the use of video display terminals (VDTs), which have been investigated as a po...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250204
更新日期:1994-02-01 00:00:00
abstract::Isasbest Ltd., an asbestos-cement factory in Israel, has established dust-preventive measures, maintained high ecological and medical standards, and assisted afflicted workers suffering from asbestos-related diseases. The problems of the handling of asbestos and its relationship to health should be approached accordin...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700100509
更新日期:1986-01-01 00:00:00