Toxic health effects including reversible macrothrombocytosis in workers exposed to asphalt fumes.

Abstract:

:We investigated an outbreak of irritative and neurotoxic symptoms associated with exposure to asphalt fumes in a commercial lighting factory; 27 symptomatic female workers were clinically assessed including hematologic testing. When compared with a laboratory reference group (n = 107), the workers' mean platelet volume (MPV) was significantly higher and mean platelet count was lower (p = 0.013 and p = 0.048, respectively). Five months later, the factory's ventilation system was substantially modified. Follow-up assessments 6 months postmodification on 15 of the original workers documented a significant decline in acute symptoms and a lowering of the subjects' mean MPV towards normal (p = 0.0007 by paired t-test). The findings suggest that reversible macrothrombocytosis (enlarged platelets) can occur among symptomatic workers exposed to asphalt fumes.

journal_name

Am J Ind Med

authors

Chase RM,Liss GM,Cole DC,Heath B

doi

10.1002/ajim.4700250214

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

279-89

issue

2

eissn

0271-3586

issn

1097-0274

journal_volume

25

pub_type

杂志文章
  • Occupational exposure to polycyclic aromatic hydrocarbons: A cross-sectional study in bars and restaurants in Santiago, Chile.

    abstract:OBJECTIVE:To evaluate indoor polycyclic aromatic hydrocarbon (PAH) concentrations in bars and restaurants and identify the main determinants of airborne PAH concentrations. METHODS:This study included 57 bars/restaurants in Santiago, Chile. PAH concentrations (ng/m(3) ) were measured using photoelectric aerosol sensor...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22616

    authors: Muñoz C,Droppelmann A,Erazo M,Aceituno P,Orellana C,Parro J,Mesias S,Marchetti N,Navas-Acien A,Iglesias V

    更新日期:2016-10-01 00:00:00

  • Assessing the accuracy of the death certificate injury at work box for identifying fatal occupational injuries in Michigan.

    abstract:BACKGROUND:Death certificates contain a box labeled "Injury at Work" which is to be marked "Yes" for all fatal occupational injuries. The accuracy of this box in Michigan is not fully characterized. METHODS:The accuracy of the Injury at Work box on the Michigan death certificate was compared to deaths identified from ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.23100

    authors: Oliveri AN,Wang L,Rosenman KD

    更新日期:2020-06-01 00:00:00

  • Smoking as a confounder in case-control studies of occupational bladder cancer in women.

    abstract:BACKGROUND:In studies in men, risk estimates on occupation and bladder cancer are distorted by about 10% when not adjusting for smoking. We examined the degree to which occupational risk estimates for bladder cancer in women are confounded by smoking, and the degree of residual confounding by inadequate control of this...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章,meta分析

    doi:10.1002/(sici)1097-0274(199907)36:1<75::aid-ajim11

    authors: 't Mannetje A,Kogevinas M,Chang-Claude J,Cordier S,González CA,Hours M,Jöckel KH,Bolm-Audorff U,Lynge E,Porru S,Donato F,Ranft U,Serra C,Tzonou A,Vineis P,Wahrendorf J,Boffetta P

    更新日期:1999-07-01 00:00:00

  • Hospitalized nonfatal injuries in the Alaskan construction industry.

    abstract:BACKGROUND:Construction industry workers are exposed to many hazards leading to fatal and nonfatal injuries. Information for nonfatal work-related injury surveillance may be vague and come from a variety of sources. METHODS:The Alaska Trauma Registry (ATR) is used as an injury surveillance tool to focus on hospitalize...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20158

    authors: Husberg BJ,Fosbroke DE,Conway GA,Mode NA

    更新日期:2005-05-01 00:00:00

  • Is self-reported pain an appropriate outcome measure in ergonomic-epidemiologic studies of work-related musculoskeletal disorders?

    abstract::Of the various overlapping approaches used to define outcome in ergonomic-epidemiologic studies of work-related musculoskeletal disorders, the most widely used are clinical diagnostic entities, whose criteria derive either from clinical examination (consisting of clinical tests in conjunction with symptoms and clinica...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章,评审

    doi:10.1002/(SICI)1097-0274(199607)30:1<93::AID-AJIM16

    authors: Schierhout GH,Myers JE

    更新日期:1996-07-01 00:00:00

  • Effect of repeated occupational exposure to lead, cessation of exposure, and chelation on levels of lead in bone.

    abstract::A sensitive K-X-ray fluorescence (K-XRF) instrument was used to measure lead levels in the tibia and patella on a series of twelve subjects who had relatively well-documented histories of lead exposure and blood lead levels. For some subjects, K-XRF measurements were taken at multiple points in time, and before and af...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700200603

    authors: Hu H,Pepper L,Goldman R

    更新日期:1991-01-01 00:00:00

  • Chronology of asbestos cancer discoveries: experimental studies of the Saranac Laboratory.

    abstract::This commentary challenges a recently published perception that Dr. Le Roy Upson Gardner had not actually discovered in 1942 that inhaled chrysotile fibers could induce malignant neoplasia in mice. The handwritten laboratory notes and some of Dr. Gardner's slides have recently been found. They verify that the tumors h...

    journal_title:American journal of industrial medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1002/ajim.4700270413

    authors: Schepers GW

    更新日期:1995-04-01 00:00:00

  • Assessment of occupational eye injury risk and severity: an analysis of Rhode Island workers' compensation data 1998-2002.

    abstract:BACKGROUND:Occupational eye injuries have been recognized as a serious health risk to workers and are in need of further investigation to develop effective interventions. METHODS:Rhode Island workers' compensation claims of ocular injury between 1998 through 2002 (n=8,877) were examined. The Current Population Survey ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20234

    authors: McCall BP,Horwitz IB

    更新日期:2006-01-01 00:00:00

  • Asbestos-induced visceral pleural fibrosis reduces pulmonary compliance.

    abstract::To determine the nature of respiratory functional impairment caused by asbestos-induced visceral pleural fibrosis (VPF) and to discover which pulmonary physiological variable best reveals it, we examined 59 asbestos-exposed construction workers having asbestos-related changes on chest radiographs. Computed tomography ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700280306

    authors: Valkila EH,Nieminen MM,Moilanen AK,Kuusisto PA,Lahdensuo AH,Karvonen JI

    更新日期:1995-09-01 00:00:00

  • Dying for work: The magnitude of US mortality from selected causes of death associated with occupation.

    abstract:BACKGROUND:Deaths due to occupational disease and injury place a heavy burden on society in terms of economic costs and human suffering. METHODS:We estimate the annual deaths due to selected diseases for which an occupational association is reasonably well established and quantifiable, by calculation of attributable f...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章,评审

    doi:10.1002/ajim.10216

    authors: Steenland K,Burnett C,Lalich N,Ward E,Hurrell J

    更新日期:2003-05-01 00:00:00

  • Change in prevalence of asbestos-related disease among sheet metal workers 1986 to 2016.

    abstract:BACKGROUND:A medical screening program began in 1986 for sheet metal workers exposed to asbestos, primarily while working alongside insulators applying spray-on asbestos materials, a practice banned in 1973. Exposure continues during maintenance, renovation, and repair. METHODS:Radiographic abnormalities among 26 397 ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22998

    authors: West GH,Sokas RK,Welch LS

    更新日期:2019-07-01 00:00:00

  • Identification of formaldehyde releasers and occurrence of formaldehyde and formaldehyde releasers in registered chemical products.

    abstract::Substances referred to as formaldehyde releasers were identified on review of the literature. Information on product categories and typical concentrations for chemical products containing formaldehyde and formaldehyde releasers was obtained from the Danish Product Register Data Base (PROBAS). As of February 1992, 62,0...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700240505

    authors: Flyvholm MA,Andersen P

    更新日期:1993-11-01 00:00:00

  • Exposure-outcome relationships between organic solvent exposure and neuropsychiatric disorders: results from a Dutch case-control study.

    abstract::In this article the material collected for a case-control study is analyzed in order to evaluate the existence of relationships between organic solvent exposure and the entitlement to disability benefits due to neuropsychiatric disorders. Questionnaires were used to collect information on 252 cases receiving compensat...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700160610

    authors: van Vliet C,Swaen GM,Volovics A,Slangen JJ,Meijers JM,de Boorder T,Sturmans F

    更新日期:1989-01-01 00:00:00

  • Efficiency of autocoding programs for converting job descriptors into standard occupational classification (SOC) codes.

    abstract:BACKGROUND:Existing datasets often lack job exposure data. Standard Occupational Classification (SOC) codes can link work exposure data to health outcomes via a Job Exposure Matrix, but manually assigning SOC codes is laborious. We explored the utility of two SOC autocoding programs. METHODS:We entered industry and oc...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22928

    authors: Buckner-Petty S,Dale AM,Evanoff BA

    更新日期:2019-01-01 00:00:00

  • Patterns and predictors of employer risk-reduction activities (ERRAs) in response to a work-related upper extremity cumulative trauma disorder (UECTD): reports from workers' compensation claimants.

    abstract:BACKGROUND:Despite being preventable, work-related upper extremity cumulative trauma disorders (UECTDs) remain problematic. This study is unique in its focus on predictors of employer risk-reduction activities (ERRAs) in response to a UECTD case. METHODS:Workers' compensation claimants (N = 537) completed a telephone ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/1097-0274(200011)38:5<489::aid-ajim1>3.0.c

    authors: Keogh JP,Gucer PW,Gordon JL,Nuwayhid I

    更新日期:2000-11-01 00:00:00

  • Reliability of data from next-of-kin: results from a case-control study of occupational and lifestyle risk factors for cancer.

    abstract:BACKGROUND:Use of surrogate responders often needs to be considered in case-control studies with a high case fatality. METHODS:Agreement between 98 colon cancer patients and their closest relative was expressed as a percentage of the exact agreement and by Kappa coefficients and intra-class correlation coefficients. ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.10266

    authors: Kaerlev L,Lynge E,Sabroe S,Olsen J

    更新日期:2003-09-01 00:00:00

  • Occupational laryngitis caused by formaldehyde: a case report.

    abstract::Formaldehyde is commonly accepted to be an allergen and irritant. However, specifically diagnosed occupational respiratory diseases caused by formaldehyde are relatively rare. Occupational laryngitis was diagnosed in a 47-year-old dairy foreman. He had been exposed for 9 years to formaldehyde emitted from a milk-packi...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章,评审

    doi:10.1002/(SICI)1097-0274(199603)29:3<275::AID-AJIM7

    authors: Roto P,Sala E

    更新日期:1996-03-01 00:00:00

  • Interleukin 1α and 1β gene variations are associated with tuberculosis in silica exposed subjects.

    abstract:INTRODUCTION:Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tubercul...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.23066

    authors: Salum KCR,de Castro MCS,Moreira VB,Nani ASF,Kohlrausch FB

    更新日期:2020-01-01 00:00:00

  • Minnesota Highway Maintenance Worker Study: cancer mortality.

    abstract::Highway maintenance workers (HMWs) have been exposed to a broad range of potentially toxic substances, including diesel fuels and exhaust, asphalts and tars, herbicides, gasoline, polynuclear aromatic hydrocarbons, benzene, and lead. The number of current and former state, county, and municipal HMWs in the United Stat...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700150507

    authors: Bender AP,Parker DL,Johnson RA,Scharber WK,Williams AN,Marbury MC,Mandel JS

    更新日期:1989-01-01 00:00:00

  • Beryllium sensitivity among workers at a Norwegian aluminum smelter.

    abstract:BACKGROUND:Sensitivity to beryllium was investigated among workers at an aluminum smelter in Norway as a consequence of the findings in an occupational exposure survey. METHODS:Three hundred and sixty-two employees and 31 reference persons were tested for sensitization to beryllium with the beryllium lymphocyte prolif...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20816

    authors: Nilsen AM,Vik R,Behrens C,Drabløs PA,Espevik T

    更新日期:2010-07-01 00:00:00

  • Occupational health outcomes for workers in the agriculture, forestry and fishing sector: implications for immigrant workers in the southeastern US.

    abstract:BACKGROUND:Workers in the Agriculture, Forestry, and Fisheries (AgFF) sector experience exposures directly related to the work itself, as well as the physical environment in which the work occurs. Health outcomes vary from immediate to delayed, and from acute to chronic. METHODS:We reviewed existing literature on the ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章,评审

    doi:10.1002/ajim.22170

    authors: Quandt SA,Kucera KL,Haynes C,Klein BG,Langley R,Agnew M,Levin JL,Howard T,Nussbaum MA

    更新日期:2013-08-01 00:00:00

  • The role of ergonomic and psychosocial workplace factors in the reporting of back injuries among U.S. home health aides.

    abstract:BACKGROUND:Due to the aging population and a shift to patient home care, home health aides (HHAs) are a fast-growing occupation. Since little is known about workplace risk factors for back injuries among HHAs, we examined the role of ergonomic and psychosocial factors in injury reporting among HHAs. METHODS:We used th...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22197

    authors: Arlinghaus A,Caban-Martinez AJ,Marino M,Reme SE

    更新日期:2013-10-01 00:00:00

  • Solubility of endotoxins from Escherichia coli and Pseudomonas aeruginosa.

    abstract:BACKGROUND:The Limulus amebocyte lysate (LAL) assay may underestimate endotoxins because only soluble endotoxins are determined. The solubility of endotoxins was, therefore, studied in two species of Gram-negative bacteria. METHODS:Cultures were grown in serum broth, cells were harvested by centrifugation and washed i...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20089

    authors: Eduard W,Westby MH,Larsson L

    更新日期:2004-10-01 00:00:00

  • Injuries due to assaults on psychiatric hospital employees in Washington State.

    abstract::In order to estimate rates and identify risk factors for assaults on employees of a state psychiatric hospital, we examined workers' compensation claims, hospital-recorded incident reports, and data collected in a survey of ward staff. Results revealed 13.8 workers' compensation claims due to assault per 100 employees...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0274(199701)31:1<92::aid-ajim14

    authors: Bensley L,Nelson N,Kaufman J,Silverstein B,Kalat J,Shields JW

    更新日期:1997-01-01 00:00:00

  • Estimation of occupational cosmic radiation exposure among airline personnel: Agreement between a job-exposure matrix, aggregate, and individual dose estimates.

    abstract:BACKGROUND:Job-exposure matrices (JEM) are used for exposure assessment in occupational studies, but they can involve errors. We assessed agreement between the Nordic Occupational Cancer Studies JEM (NOCCA-JEM) and aggregate and individual dose estimates for cosmic radiation exposure among Finnish airline personnel. M...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22705

    authors: Talibov M,Salmelin R,Lehtinen-Jacks S,Auvinen A

    更新日期:2017-04-01 00:00:00

  • Histologic differences in occupational risks of lung cancer incidence.

    abstract::A five-year total community study of lung cancer incidence by occupation revealed that 1) virtually all the cases occurred in smokers; 2) all major histologic types of lung cancer were strongly associated with smoking behavior; 3) in most high-risk occupations the significant elevations of risk were limited to one or ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700030409

    authors: Morton WE,Treyve EL

    更新日期:1982-01-01 00:00:00

  • Epidemiologic studies of Scottish oil shale workers: I. Prevalence of skin disease and pneumoconiosis.

    abstract::In an epidemiologic study of 6,359 oil shale workers, 1,664 (46.7%) of 3,566 survivors were investigated. No excess of skin disease (as reported in response to a questionnaire) was found in men exposed to oil or dust, whether compared to men who were not exposed to oil or dust or to coalminers. A low prevalence of sim...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.4700090503

    authors: Seaton A,Louw SJ,Cowie HA

    更新日期:1986-01-01 00:00:00

  • Lung cancer risk among construction workers in California, 1988-2007.

    abstract:BACKGROUND:Although lung cancer risks can vary by race/ethnicity and by construction occupation, these risks have not been examined extensively. METHODS:This study analyzed 110,937 lung cancer cases identified from the California Cancer Registry between 1988 and 2007. Mean age at diagnosis, proportion diagnosed at an ...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22010

    authors: Calvert GM,Luckhaupt S,Lee SJ,Cress R,Schumacher P,Shen R,Tak S,Deapen D

    更新日期:2012-05-01 00:00:00

  • Parkinson's disease and occupation: differences in associations by case identification method suggest referral bias.

    abstract:METHODS:We used a population-based sample of 403 Parkinson's disease cases and 405 controls to examine risks by occupation. Results were compared to a previous clinic-based analysis. RESULTS:With censoring of jobs held within 10 years of diagnosis, the following had significantly or strongly increased risks: social sc...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.22272

    authors: Teschke K,Marion SA,Tsui JK,Shen H,Rugbjerg K,Harris MA

    更新日期:2014-02-01 00:00:00

  • Reducing occupation-based disparities related to tobacco: roles for occupational health and organized labor.

    abstract:BACKGROUND:Persistent and growing occupation-based disparities related to tobacco pose a serious public health challenge. Tobacco exacts a disproportionate toll on individuals employed in working class occupations, due to higher prevalence of smoking and exposure to secondhand smoke among these workers compared to othe...

    journal_title:American journal of industrial medicine

    pub_type: 杂志文章

    doi:10.1002/ajim.20026

    authors: Barbeau EM,McLellan D,Levenstein C,DeLaurier GF,Kelder G,Sorensen G

    更新日期:2004-08-01 00:00:00