Abstract:
:A sensitive K-X-ray fluorescence (K-XRF) instrument was used to measure lead levels in the tibia and patella on a series of twelve subjects who had relatively well-documented histories of lead exposure and blood lead levels. For some subjects, K-XRF measurements were taken at multiple points in time, and before and after chelation with EDTA (ethylenediamine tetraacetic acid). Results confirm that K-XRF measured bone lead levels correspond to cumulative blood lead indices and not to current blood lead levels. Moreover, the data suggest that bone lead levels; (1) correspond to urinary lead following the EDTA mobilization test unless previous chelation has occurred; (2) rise initially after lead exposure ceases and blood lead levels decrease, probably from redistribution from soft tissue, and then fall; and (3) do not decrease with a 3- to 5-day course of therapeutic EDTA chelation. K-XRF levels in the patella were noted to decrease more rapidly than levels in the tibia after cessation of lead exposure, a finding that probably reflects the greater turnover of lead in trabecular bone than in cortical bone.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Hu H,Pepper L,Goldman Rdoi
10.1002/ajim.4700200603subject
Has Abstractpub_date
1991-01-01 00:00:00pages
723-35issue
6eissn
0271-3586issn
1097-0274journal_volume
20pub_type
杂志文章abstract::Surveillance of cause-specific mortality patterns by occupation and industry through the use of death certificate records is a simple and relatively inexpensive approach to the generation of leads as to potential occupational disease problems. Researchers from the National Institute for Occupational Safety and Health ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700110309
更新日期:1987-01-01 00:00:00
abstract::The aim of the study was to evaluate the genotoxic risk to medical personnel concurrently exposed to ionizing radiation and antineoplastics, using changes in their lymphocyte cell genome as a bioindicator. The study comprised 12 female nurses employed in the nuclear medicine hospital department and an equal number of ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270610
更新日期:1995-06-01 00:00:00
abstract::Exposure to mineral dust was studied among construction workers (N = 437) with the aid of a questionnaire and a chest X-ray examination of the lungs. The results of the questionnaire showed that 81% of the construction workers had been exposed to asbestos. Exposure had occurred in all of the occupational groups studie...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700210411
更新日期:1992-01-01 00:00:00
abstract::The Bassett Farm Safety and Health Project was started in 1980 when Drs. May and Pratt made clinical observations on respiratory illnesses in farmers. The initial work involved the investigation of clinical syndromes associated with dust exposures and, from there, environmental dust studies. The current scope of work ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700180407
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:The ability of workers to accurately recall exposures that occur on the day of their injury is considered a potential limitation of case-crossover studies. This study assessed validity of occupational exposures reported by uninjured workers at a Midwestern meatpacking plant. METHODS:One hundred thirty-six wo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20721
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Diesel exhaust is considered a probable human carcinogen by the International Agency for Research on Cancer (IARC). The epidemiologic evidence rests on studies of lung cancer among truck drivers, bus drivers, shipyard workers, and railroad workers. The general public is exposed to diesel exhaust in ambient a...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199809)34:3<220::aid-ajim3
更新日期:1998-09-01 00:00:00
abstract::To confirm the relationship between exposure to coal tar pitch volatiles and bladder cancer among primary aluminum production workers, we carried out a case-control study among blue-collar workers who had worked more than 1 year between 1950-1979 in a major plant using mostly the Soderberg process in the Province of Q...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270303
更新日期:1995-03-01 00:00:00
abstract::A 5-year prospective analysis tests the hypothesis that coal miners who have impaired respiratory health also experience greater numbers of disability days due to occupational injury. Occupational and respiratory health information collected for the period 1977 through 1981 by the National Institute for Occupational S...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700070409
更新日期:1985-01-01 00:00:00
abstract::Injury is the leading cause of death in adolescence, with the highest rates for 15- to 19-year-olds, an age span also marked, for many, by entry into the workforce. Occupational injuries affecting youth occur in the context of the larger problem of injury affecting children and adolescents. An understanding of the bro...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240307
更新日期:1993-09-01 00:00:00
abstract::A cross-sectional prevalence study of 120 public school custodians was carried out. The purposes were 1) to investigate the prevalence of asbestos-related disease in a group of custodians at risk for asbestos exposure in public schools and 2) to determine the proportion with disease attributable to exposures in school...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700190305
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Exposure to disinfectants among healthcare workers has been associated with respiratory health effects, in particular, asthma. However, most studies are cross-sectional and the role of disinfectant exposures in asthma development requires longitudinal studies. We investigated the association between occupati...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23067
更新日期:2020-01-01 00:00:00
abstract::Respiratory health variables were studied cross-sectionally in 227 employees of a plastics molding facility where numerous complaints had been apparently associated with the use of azodicarbonamide foaming agent in injection molding. Pre- and postshift respiratory status measures and azodicarbonamide concentrations we...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700110109
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Rates of occupational injury among immigrant workers are widely believed to be underestimated. The goal of this study was to enhance understanding of the burden of occupational injury and the work organization factors underlying injury among immigrant Latino residential construction workers. METHODS:Prospec...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22014
更新日期:2012-08-01 00:00:00
abstract::In an epidemiologic study of 6,359 oil shale workers, 1,664 (46.7%) of 3,566 survivors were investigated. No excess of skin disease (as reported in response to a questionnaire) was found in men exposed to oil or dust, whether compared to men who were not exposed to oil or dust or to coalminers. A low prevalence of sim...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700090503
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Work-related musculoskeletal disorders (MSDs) of the upper extremities are a major problem globally, though most relevant studies have been reported from high income countries. AIMS AND METHODS:The prevalence of neck and shoulder pain and its association with work-related physical and psychosocial factors a...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20562
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Hospitalization-based estimates of trends in injury incidence are also affected by trends in health care practices and payer coverage that may differentially impact minor injuries. This study assessed whether implementing a severity threshold would improve occupational injury surveillance. METHODS:Hospital ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22329
更新日期:2014-08-01 00:00:00
abstract::An analysis of reported birth record variables by parental occupation suggests that certain birth outcomes may identify toxic or carcinogenic occupational exposures of the parents. Fathers coded to an asbestos and insulation worker rubric sired fewer plural births, and more stillbirths than expected. A number of other...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700160214
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Occupational safety and health (OSH) programs are a strategy for protecting workers' health, yet there are few peer-reviewed reports on methods for assessing them, or on the prevalent characteristics of OSH programs, especially in small businesses. METHODS:We adapted an occupational safety and health admini...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10336
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Following the 1990-1991 Gulf War, Gulf War veterans (veterans) reported health symptoms more commonly than non-deployed groups. This article examines symptom persistence, incidence and prevalence 20 years on. METHODS:In 2000-2003 and 2011-2012, a 63-item symptom checklist was administered to 697 veterans an...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22490
更新日期:2015-12-01 00:00:00
abstract::This commentary challenges a recently published perception that Dr. Le Roy Upson Gardner had not actually discovered in 1942 that inhaled chrysotile fibers could induce malignant neoplasia in mice. The handwritten laboratory notes and some of Dr. Gardner's slides have recently been found. They verify that the tumors h...
journal_title:American journal of industrial medicine
pub_type: 传,历史文章,杂志文章
doi:10.1002/ajim.4700270413
更新日期:1995-04-01 00:00:00
abstract::Several studies have indicated an increased risk for cancer of the urinary bladder among hairdressers. In a Danish linkage between census data and cancer register data both male and female hairdressers have an elevated risk for bladder cancer. The risk for lung cancer is close to unity, indicating that occupational fa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700170206
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:We developed a systematic, data-driven approach to estimate metrics of occupational exposure to lead to aid in epidemiologic analyses in a case-control study of kidney cancer. METHODS:Probability of exposure to ten lead sources was assigned using decision rules developed from an extensive literature review ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22912
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVES:Few Canadian data sources allow the examination of disparities by ethnicity, language, or immigrant status in occupational exposures or health outcomes. However, it is possible to document the mechanisms that can create disparities, such as the over-representation of population groups in high-risk jobs. We e...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20845
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Field-portable instruments can offer expeditious analytical results to health professionals in field settings and in areas lacking laboratory infrastructure. This study further evaluated an electroanalytical field-portable instrument, which rapidly analyzes blood lead concentrations. METHODS:A portable anod...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20096
更新日期:2004-12-01 00:00:00
abstract::Several studies on the mortality of chemists have revealed a lower overall mortality but an excess of deaths from certain diseases, in particular, cancers. This study determined the causes of mortality of 4,012 chemists among 14,884 members of The Royal Society of Chemistry who were followed for a period of 25 years. ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230409
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND:From 1970 through 1997, 17 intracranial neoplasms were identified among 6,800 employees of a petrochemical research facility. This investigation describes the case-series. METHODS:The intracranial neoplasms were identified by self reports and record linkages, and were confirmed by medical records and a path...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199910)36:4<450::aid-ajim6
更新日期:1999-10-01 00:00:00
abstract::Skin symptoms of "yusho" and their change thereafter are described. In the early stage, skin eruptions were the most prominent and impressive features of yusho. Acneiform eruptions and pigmentation were most conspicuous. With the passage of time, there is some improvement and most patients now have few eruptions, exce...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:Farmers have been previously reported to have higher rates of depression and suicide compared to other occupations. Comparisons of depressive symptoms and risk factors for states should increase understanding of depression in farmers. METHODS:Representative samples of 385 Iowa and 470 Colorado male principa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(200004)37:4<382::aid-ajim8
更新日期:2000-04-01 00:00:00
abstract:AIMS:To examine the pattern of psychosocial risk exposures at work among wage-earners in Spain in 2005 and 2010, and to analyze changes in exposure inequalities by gender and job category. METHODS:Psychosocial exposures were compared using the COPSOQ-ISTAS21 method, based on two surveys representative of the Spanish w...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22334
更新日期:2014-09-01 00:00:00
abstract::In the course of a health screening for construction carpenters, 127 subjects underwent blood lead testing, administration of detailed questionnaires, and in vivo measurement of bone lead levels with a 109Cd K-X-ray fluorescence (K-XRF) instrument. The mean age of subjects was 48.5 (SD = 9.8) years. Blood lead levels ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260211
更新日期:1994-08-01 00:00:00