Abstract:
:The aim of the study was to evaluate the genotoxic risk to medical personnel concurrently exposed to ionizing radiation and antineoplastics, using changes in their lymphocyte cell genome as a bioindicator. The study comprised 12 female nurses employed in the nuclear medicine hospital department and an equal number of matched controls. For each examinee, both conventional structural chromosomal aberration analysis and sister chromatid exchange test (SCE) were carried out. According to Student's t-test, neither the incidence of structural chromosomal aberrations (p > 0.6) nor the mean SCE-frequency rate (p > 0.3) were significantly increased among the exposed subjects. Nevertheless, in those exposed, irreparable chromosomal damages and wide SCE-ranges were observed. Such findings suggest the possibility of genotoxic implications of concurrent occupational exposure to ionizing radiation and antineoplastic drugs.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Brumen V,Horvat D,Trosić Idoi
10.1002/ajim.4700270610subject
Has Abstractpub_date
1995-06-01 00:00:00pages
871-6issue
6eissn
0271-3586issn
1097-0274journal_volume
27pub_type
杂志文章abstract::A retrospective exposure assessment study in the automotive parts industry conducted in conjunction with a cancer mortality and respiratory morbidity study [Kennedy et al. (1989): Am J Ind Med 15:627-641; Eisen et al. (1992): Am J Ind Med 22:809-824; Tolbert et al. (1992): Scand J Work Environ Health 18:351-360] descr...
journal_title:American journal of industrial medicine
pub_type: 历史文章,杂志文章
doi:10.1002/ajim.4700260505
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:A major French chlorine chemical plant (chlor-alkali process with diaphragm cell and manufacturing of organochlorine chemicals) has used or produced known or suspected carcinogenic compounds. METHODS:A cohort study, based on the plant occupational health service and the regional cancer registry, analyzed th...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22069
更新日期:2012-09-01 00:00:00
abstract::Since 1988, the National Institute for Occupational Safety and Health (NIOSH) has notified workers who were subjects in occupational epidemiology studies of the study findings ("worker notification"). This paper describes seven notifications and the worker's reactions to them. The chemicals of interest in the studies ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270403
更新日期:1995-04-01 00:00:00
abstract::Objective measures of exposure furnished by dust monitoring are both costly and time consuming and require a sufficient level of technology. However, they are important in demonstrating exposure-response relationships, in furnishing information necessary to establish environmental control levels, and to assess if inte...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240406
更新日期:1993-10-01 00:00:00
abstract:INTRODUCTION:The prevalence of violence to first responders is reported in ranges of approximately 40% to 90%. Pennsylvania has a felonious assault statute to address such violence, but the prosecutorial process has been noted to cause first-responder dissatisfaction. METHODS:An exploratory qualitative study using ind...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23036
更新日期:2019-11-01 00:00:00
abstract::The occupational injury experience of the U.S. and Australian construction industries for 1988-1991 was compared to identify similarities and differences in risk and to share information vital for planning strategies for prevention. There were 4,158 deaths in the U.S. and 264 in the Australian construction industries....
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199608)30:2<202::AID-AJIM1
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:This study sought to identify impacts of compensation system characteristics on doctors in Québec and Ontario. METHODS:(i) Legal analysis; (ii) Qualitative methods applied to documentation and individual and group interviews with doctors (34) and other system participants (31); and (iii) Inter-jurisdictiona...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22651
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:No information exists on the differences between teenagers with work permits and teenagers without work permits in regards to workplace injury, near-miss incidents, and safety training. METHODS:In May 2003, an anonymous questionnaire was administered to 7,506 teens attending high school throughout the five ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20301
更新日期:2006-05-01 00:00:00
abstract::Studies describing respiratory health hazards for workers in swine production facilities have been published in the United States, Sweden, Canada, the Netherlands, and Denmark. Up to 50% of these workers experience bronchitis, organic dust toxic syndrome, hyper-reactive airways disease, chronic mucous membrane irritat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199601)29:1<33::AID-AJIM5>
更新日期:1996-01-01 00:00:00
abstract::Over-exposure to lead was identified among developmentally disabled workers engage in furniture refinishing at two separate sites. The index case was identified at the first site by a public health nurse assigned to provide care to some of the workers. Referral to a regional occupational health clinic initiated an exp...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199808)34:2<191::aid-ajim1
更新日期:1998-08-01 00:00:00
abstract::Lung tissue of a worker in an abrasive manufacturing plant, whose duration of dust exposure was about 10 years, was analyzed by means of bulk analysis and in situ analytical electron microanalysis. The content of the total dust in the lung was 120 mg/g of the dried lung tissue. This value is close to the average conce...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700140205
更新日期:1988-01-01 00:00:00
abstract::A death certificate mortality odds ratio study of seven cancer sites was conducted by using 1979-1984 data on Illinois deaths in white and black males. Cancer sites selected include stomach, pancreas, lung, prostate, bladder, brain, and non-Hodgkin's lymphomas. This surveillance study was undertaken to detect occupati...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700150609
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:A program of medical evaluation for former Savannah River Site (SRS) workers at health effects due to exposures to hazardous or radioactive agents was conducted. METHODS:This study includes data from 1,368 participants aged 45 years or older who were assessed regarding work-history and exposures to industri...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20224
更新日期:2005-11-01 00:00:00
abstract::Asbestos has been widely used in the refinery and petrochemical sector. Mesothelioma has occurred among maintenance employees, and it was hypothesized that mesothelioma is a marker for exposures which might increase lung cancer risk. A death certificate-based case-control study of mesothelioma and lung cancer from 198...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199611)30:5<610::AID-AJIM9
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Previous epidemiological studies investigating modification of organophosphate (OP) neurotoxicity by xenobiotic metabolizing enzymes (XMEs) polymorphisms have produced inconsistent results. METHODS:A cross-sectional study of 301 emerging farmers was conducted. Neurotoxicity testing included forward and back...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22790
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Occupational exposure to vinyl chloride monomer (VCM) has been established as a cause of hepatocellular carcinoma (HCC) and liver angiosarcoma (ASL). However, some controversy remains due to conflicting results on liver cirrhosis, and to evidence on HCC based on few confirmed cases. The aim of the study is t...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22922
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Autopsied lungs from 29 hard rock miners were investigated to determine the relationship of the dust content to pathology, radiology, and occupational exposure. METHODS:Each lung was divided horizontally into three sections. Pathological and radiological studies and chemical analyses were carried out on sam...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20589
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:In recent decades, the use of artificial nails including methacrylates (MAs) has increased. This study presents the first two clinical cases of occupational asthma (OA) caused by sculptured nails containing MAs. METHODS:In both cases, OA was diagnosed on the basis of a work simulation test combined with the...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20633
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:The US military is a large, well-defined occupational cohort offering tremendous opportunities to study risk factors for important health outcomes. This article describes our nested case-control methods to evaluate risk factors for fatal motor vehicle crashes (MVC) within all Service branches in a 1991 Gulf ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20190
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Workers in the Agriculture, Forestry, and Fisheries (AgFF) sector experience exposures directly related to the work itself, as well as the physical environment in which the work occurs. Health outcomes vary from immediate to delayed, and from acute to chronic. METHODS:We reviewed existing literature on the ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.22170
更新日期:2013-08-01 00:00:00
abstract::Substances referred to as formaldehyde releasers were identified on review of the literature. Information on product categories and typical concentrations for chemical products containing formaldehyde and formaldehyde releasers was obtained from the Danish Product Register Data Base (PROBAS). As of February 1992, 62,0...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240505
更新日期:1993-11-01 00:00:00
abstract:METHODS:We used a population-based sample of 403 Parkinson's disease cases and 405 controls to examine risks by occupation. Results were compared to a previous clinic-based analysis. RESULTS:With censoring of jobs held within 10 years of diagnosis, the following had significantly or strongly increased risks: social sc...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22272
更新日期:2014-02-01 00:00:00
abstract::Organophosphate (OP)-related systemic illnesses reported to the Worker Health and Safety (WH&S) Branch, and restricted OP-related agricultural use data reported to the Information Services Branch at the California Department of Food and Agriculture (CDFA) (now CAL-EPA) during 1984-1988 were used to assess factors asso...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199705)31:5<572::aid-ajim1
更新日期:1997-05-01 00:00:00
abstract::Very sensitive and precise analytical methods for measuring total porphyrin excretion and the relative amounts of different porphyrins in urine are required in order to monitor the biological effects of porphyrinogenic substances in workers and the general population. Many analytical steps of a HPLC method for measuri...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700040409
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Several case-control studies have found an association between chronic beryllium disease (CBD) and HLA-DPB1 gene variants. However, the relationship between HLA-DPB1 and beryllium sensitization, and whether the presence of one or two HLA-DPB1(Glu69) alleles is differentially associated with CBD and beryllium...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,多中心研究
doi:10.1002/ajim.20045
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Production of asbestos-cement products in Brazil started in the 1940s, peaked in the 60-70s and is still an active industry. This study was designed to assess the non-malignant effects of asbestos exposure in the asbestos-cement industry in Brazil. METHODS:A group of 828 former asbestos-cement workers enrol...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1095
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:After cryptosporidiosis was reported in three workers caring for preweaned calves at an academic research laboratory, we sought to identify cases, determine risk factors, and implement control measures. METHODS:A cryptosporidiosis case was defined as diarrhea duration ≥72 hr, abdominal cramps, or vomiting i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22630
更新日期:2017-02-01 00:00:00
abstract::Several studies have indicated an increased risk for cancer of the urinary bladder among hairdressers. In a Danish linkage between census data and cancer register data both male and female hairdressers have an elevated risk for bladder cancer. The risk for lung cancer is close to unity, indicating that occupational fa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700170206
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Potential confounding or effect modification by employment status is frequently overlooked in pregnancy outcome studies. METHODS:To characterize how employed and non-employed women differ, we compared demographics, behaviors, and reproductive histories by maternal employment status for 8,343 mothers of cont...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22700
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Commercial fishing is a global industry that has been frequently classified as high-risk. The use of detailed surveillance data is critical in identifying hazards. METHODS:The purpose of this study was to provide updated statistics for the entire US fishing industry during 2010-2014, generate fleet-specific...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22761
更新日期:2018-01-01 00:00:00