Abstract:
:Studies describing respiratory health hazards for workers in swine production facilities have been published in the United States, Sweden, Canada, the Netherlands, and Denmark. Up to 50% of these workers experience bronchitis, organic dust toxic syndrome, hyper-reactive airways disease, chronic mucous membrane irritation, and other respiratory effects. These studies clearly point to the fact that this occupational environment poses a significant health risk hazard, and that control methods are needed to protect the worker. Before precise control strategies can be developed, implemented, and evaluated, dose-response studies are required to determine acceptable target levels for exposure. A previous manuscript described the development of multiple regression equations characterizing the relationships between environmental exposures and pulmonary response in a cohort of 207 swine producers. Baseline pulmonary function was included as a significant predictor of cross-shift decrements in pulmonary function in addition to personal measurements of dust, endotoxin, and ammonia concentrations. These equations were then used to predict specific exposure levels of dust and ammonia that could be expected to elicit significant decrements in cross-shift pulmonary function. This paper presents the results from analysis of follow-up data obtained on this same cohort 2 years after the initial measurements. At the second measurement period of the study (time-2), swine workers were found to have a mean cross-shift decrease in FEV1 of 2%. Cross-shift change in FEV1 was significantly correlated with personal exposures to total dust, total endotoxin, respirable endotoxin, and ammonia. The magnitude of the decrease in FEV1 was associated with increasing airborne concentrations of these environmental parameters thus confirming the dose-response relationship observed in the initial study (time-1). The correlation of dust with FEV1 changes in workers with more than 6 years of exposure (time-1 data) and more than 10 years of exposure (time-2 data) suggests that dust exposure is an important factor in chronic respiratory disease. Additionally, the correlation of endotoxins with FEV1 changes in the group with less than 6 years exposure (time-2 data) suggests endotoxins may have more significance for subacute respiratory effects. The agreement between observed cross-shift FEV1 changes measured in time-2 with changes predicted using regression equations derived from time-1 data demonstrates a consistent dose-response relationship over time for this cohort of swine production workers. This finding provides further support for conclusions of the previous study that levels of 2.5 mg/m3 (total dust) and 7.5 ppm (ammonia) are reasonable guidelines for occupational exposure limits in this environment.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Reynolds SJ,Donham KJ,Whitten P,Merchant JA,Burmeister LF,Popendorf WJdoi
10.1002/(SICI)1097-0274(199601)29:1<33::AID-AJIM5>subject
Has Abstractpub_date
1996-01-01 00:00:00pages
33-40issue
1eissn
0271-3586issn
1097-0274pii
10.1002/(SICI)1097-0274(199601)29:1<33::AID-AJIM5>journal_volume
29pub_type
杂志文章abstract:OBJECTIVES:Few Canadian data sources allow the examination of disparities by ethnicity, language, or immigrant status in occupational exposures or health outcomes. However, it is possible to document the mechanisms that can create disparities, such as the over-representation of population groups in high-risk jobs. We e...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20845
更新日期:2010-09-01 00:00:00
abstract::In the past 10 years there has been growing awareness among occupational health professionals worldwide of the large burden of illness associated with musculoskeletal disorders of the neck and upper limbs. It has been suggested that these disorders are associated with highly repetitive work and are due, at least in pa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,meta分析
doi:10.1002/ajim.4700190111
更新日期:1991-01-01 00:00:00
abstract::This study assesses the causes of medical surveillance changes leading to specialist referral from one isocyanate-using company where 39 workers (about 20% of all employees) were referred to a hospital occupational clinic during a 5-year period for concerns regarding their surveillance respiratory questionnaire or spi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199901)35:1<87::aid-ajim12
更新日期:1999-01-01 00:00:00
abstract:INTRODUCTION:Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tubercul...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23066
更新日期:2020-01-01 00:00:00
abstract::The most daunting problem in community-based studies of occupational cancer is retrospective exposure assessment. To avoid the error involved in using job title as the exposure variable or self-report of exposure, our team developed an approach based on expert judgment applied to job descriptions obtained by interview...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199703)31:3<280::aid-ajim3
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:Construction is a hazardous occupation, with Latino (Hispanic) workers at a greater risk for death than other ethnicities/races. Latinos accounted for over half of construction injuries involving days away from work in Nevada in 2006. METHODS:This study recruited 30 Latino construction workers from three So...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20735
更新日期:2010-02-01 00:00:00
abstract::In August, 1990, a regional transit authority began removing paint on two overhead bridges on a commuter railroad line running through a residential neighborhood of Lynn, Massachusetts, an industrial city north of Boston. The contracted work involved the sandblasting of existing bridge paint to prepare the surface for...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230126
更新日期:1993-01-01 00:00:00
abstract::Occupational diseases are now being assessed at the cellular and molecular levels; this presents new opportunities for prevention and control [Calleman et al., 1978; Ong et al., 1987; Stejskal et al., 1989; Welch and Cullen, 1988; Garry et al., 1989]. The key to these opportunities is the ability to detect biological ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700200402
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Farmworkers who delay treatment after workplace injuries may increase injury severity and experience longer recovery times. To understand why farmworkers delay treatment we employed a mixed-methods analysis of 393 farmworker injury narratives from the National Agricultural Workers Survey (NAWS). METHODS:Fir...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22380
更新日期:2015-02-01 00:00:00
abstract::Long-term exposure to lead is known to cause a variety of neurotoxic manifestations, including symptoms of depression. Dimercaptosuccinic acid (DMSA), a recently approved oral chelating agent, can diminish the body burden of lead, but few cases of documented clinical improvement following treatment have been reported....
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240606
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND:Thoroughbred horse farm workers self-report a high frequency of work-related injuries and pain. However, an analysis of Thoroughbred horse farm workers' compensation injury claims is absent from the literature, yet may benefit worker safety. METHODS:We analyzed workers' compensation insurance firm data cont...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23159
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Production of asbestos-cement products in Brazil started in the 1940s, peaked in the 60-70s and is still an active industry. This study was designed to assess the non-malignant effects of asbestos exposure in the asbestos-cement industry in Brazil. METHODS:A group of 828 former asbestos-cement workers enrol...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1095
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:We sought to gain insight into workers' knowledge, beliefs, and attitudes on the subject of testing for genetic susceptibility to beryllium. METHODS:Five focus groups were held with 30 current and former beryllium workers and nine family members. Audio recordings were transcribed and assessed by hierarchica...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20962
更新日期:2011-07-01 00:00:00
abstract::Blood histamine levels were measured by the bioassay of histamine (on an isolated strip of guinea pig ileum) in workers exposed to cotton dust in a textile mill in Ahmedabad. Byssinotic subjects showed very high levels of blood histamine as compared to nonbyssinotic and control subjects. The blood histamine levels wer...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120409
更新日期:1987-01-01 00:00:00
abstract::Several studies on the mortality of chemists have revealed a lower overall mortality but an excess of deaths from certain diseases, in particular, cancers. This study determined the causes of mortality of 4,012 chemists among 14,884 members of The Royal Society of Chemistry who were followed for a period of 25 years. ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230409
更新日期:1993-04-01 00:00:00
abstract::This study examined the association between exposure to occupational hazards and pregnancy outcomes using data from a case-control study conducted in 29 hospitals in Shanghai, China. The sample included 1,875 perinatal deaths and newborns with birth defects and the same number of controls. Information on mother's expo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700210312
更新日期:1992-01-01 00:00:00
abstract::A model was created to assess occupational exposure to extremely low-frequency magnetic fields (ELF-MF) among semiconductor fabrication-room (fab) workers. This model was based on the assumption that each subject's exposure arose from being near identifiable ELF-MF sources or being in areas with high ELF-MF levels. To...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280608
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND:A major French chlorine chemical plant (chlor-alkali process with diaphragm cell and manufacturing of organochlorine chemicals) has used or produced known or suspected carcinogenic compounds. METHODS:A cohort study, based on the plant occupational health service and the regional cancer registry, analyzed th...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22069
更新日期:2012-09-01 00:00:00
abstract::A death certificate based case-control study of lung cancer in two Ontario cities was performed to estimate the risk of lung cancer attributable to occupation in Ontario, and to estimate the proportion of occupational lung cancers receiving compensation from the Workers' Compensation Board. Occupation and industry wer...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270112
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Many professional emergency responders (ERs) who belong to the Korean National Emergency Management Agency (NEMA) have been cross-trained and serve multiple roles. As such, firefighters and other ERs in Korea are exposed to similar occupational hazards. This study was conducted to estimate cancer morbidity i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22068
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Occupational Cancer Monitoring (OCCAM) is an Italian organization that monitors occupational cancers, by area and industrial sector, by retrieving cases and employment history from official databases. OCCAM previously estimated a relative risk (RR) of lung cancer of about 1.32 among "metal treatment" workers...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.21004
更新日期:2012-01-01 00:00:00
abstract::This study uses the National Mortality Followback Survey of 1986 to identify the top five Sentinel Health Events Occupational [SHE(O)s], the five leading causes of death, and to ascertain the primary occupations and industries associated with these. We found that, as expected, cardiovascular diseases were four of the ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270205
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:Opioid use is rising in the US and may cause special problems in workers compensation cases, including addiction and preventing a return to work after an injury. OBJECTIVE:This study evaluates a physician-level intervention to curb opioid usage. An insurer identified patients with out-of-guideline opioid ut...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22779
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Although there are many studies on working adolescents, information on youth who simultaneously hold jobs on both a farm and in other sectors of the economy is lacking. METHODS:Six high schools in rural Minnesota were evaluated for adolescent work practices and injury incidence. A 20-page self-administered ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10095
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:Many authorities are concerned about the rising use and the potential overuse of opioid pain medications. A study of opioid prevalence and dosage in Ohio's workers' compensation (WC) system was conducted, with comparisons made to opioid use in other WC and non-WC settings. METHODS:Systematic literature revi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.21021
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:While low dose computed tomography (LDCT) screening for lung cancer is recommended for high-risk smokers, ages 55-74 years, information about asbestos exposure may not be routinely elicited. Asbestos exposure is associated with declining respiratory function over time; however, the effect of a history of asb...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22571
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Evidence regarding the unequal burden of occupational injuries between workers employed by temporary agencies and those in standard employment arrangements is unclear. Studies range from no significant differences in risk to substantial increased risk for temporary workers. The purpose of this study is to co...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20728
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Silicosis is a progressive lung disease resulting from the inhalation of respirable crystalline silica. Lung transplantation is the only treatment for end-stage silicosis. The aim of this study was to analyze the survival experience following lung transplantation among patients with silicosis. METHODS:We re...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22687
更新日期:2017-03-01 00:00:00
abstract::In view of the increasing incidence of diseases such as gastritis and ulcers in workers exposed to noise, we assessed whether noise does in fact affect gastric secretion. Then, considering the conflicting findings published on the effects of noise on gastric secretion, we also investigated whether the response was rel...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260310
更新日期:1994-09-01 00:00:00
abstract::The aim of this study is to determine the validity of the ICD-9 for diagnostic classification of soft tissue disorders of the neck and upper limb, using routinely collected data at a large steel company. The documentation in the clinical chart served as the gold standard. First, the overall accuracy of identifying the...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199602)29:2<171::AID-AJIM7
更新日期:1996-02-01 00:00:00