Dimercaptosuccinic acid in the treatment of depression following lead exposure.

Abstract:

:Long-term exposure to lead is known to cause a variety of neurotoxic manifestations, including symptoms of depression. Dimercaptosuccinic acid (DMSA), a recently approved oral chelating agent, can diminish the body burden of lead, but few cases of documented clinical improvement following treatment have been reported. We report a case of moderate to severe depression in a long-term lead worker that appeared to respond dramatically to DMSA. This response suggests a possible therapeutic role for DMSA in the treatment of depression in lead-exposed patients.

journal_name

Am J Ind Med

authors

Frumkin H,Gerr F

doi

10.1002/ajim.4700240606

subject

Has Abstract

pub_date

1993-12-01 00:00:00

pages

701-6

issue

6

eissn

0271-3586

issn

1097-0274

journal_volume

24

pub_type

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