Abstract：
BACKGROUND:There is growing evidence that exposure to organic solvents can play a role in the etiology of rheumatoid arthritis (RA). This prospective cohort study aimed to investigate the association between RA and toluene exposure. METHODS:The study cohort consisted of Korea Occupational Safety and Health Agency data from male workers exposed to toluene who had undergone a toluene-associated special medical examination at least once between January 1, 2000 and December 31, 2004 (n = 148,870). The morbidity from RA based on hospital admission records was estimated from 2000 to 2005 using National Health Insurance Claim Data. The standardized admission ratio (SAR) for RA was calculated with reference to the general population. Levels of urinary hippuric acid (HA), a metabolite of toluene, were measured and used for exposure assessment. RESULTS:Toluene-exposed workers were at an elevated risk of seropositive rheumatoid arthritis (ICD-10 code M05) with an SAR of 2.38 (95% confidence interval [CI]: 1.14-4.37) and other rheumatoid arthritis (M06) with an SAR of 1.22 (95% CI: 0.91-1.59). When data were stratified according to the duration of toluene exposure and by tertiles of urinary HA level, no significant difference was apparent. CONCLUSION:SARs of the toluene-exposed workers are higher than that of the general reference population, indicating that exposure to toluene may contribute to an increased risk of RA. Further studies of toluene-exposed workers with longer follow-up are needed.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Min YS,Lee S,Kim M,Ahn YSdoi
10.1002/ajim.23226subject
Has Abstractpub_date
2021-01-29 00:00:00eissn
0271-3586issn
1097-0274pub_type
杂志文章abstract：:Since 1988, the National Institute for Occupational Safety and Health (NIOSH) has notified workers who were subjects in occupational epidemiology studies of the study findings ("worker notification"). This paper describes seven notifications and the worker's reactions to them. The chemicals of interest in the studies ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700270403
更新日期：1995-04-01 00:00:00
abstract：:The Bassett Farm Safety and Health Project was started in 1980 when Drs. May and Pratt made clinical observations on respiratory illnesses in farmers. The initial work involved the investigation of clinical syndromes associated with dust exposures and, from there, environmental dust studies. The current scope of work ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700180407
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:The peripheral nerve conduction velocity (NCV), distribution of nerve conduction velocities (DCV), somatosensory, visual, and brainstem auditory evoked potentials (SEP, VEP, and BAEP, respectively), event-related potential (P300), computerized static posturography with spectral analysis (postural balance), a...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：10.1002/(sici)1097-0274(200002)37:2<193::aid-ajim5
更新日期：2000-02-01 00:00:00
abstract：:This retrospective analysis reviews the clinical experience of a major urban referral hospital with diffuse malignant pleural mesothelioma during the 14-year period from 1973 through 1986. Seventy-five cases of definite or equivocal mesothelioma were identified. There were four cases of primary malignant peritoneal me...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700160405
更新日期：1989-01-01 00:00:00
abstract：:In the past 10 years there has been growing awareness among occupational health professionals worldwide of the large burden of illness associated with musculoskeletal disorders of the neck and upper limbs. It has been suggested that these disorders are associated with highly repetitive work and are due, at least in pa...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,meta分析
doi：10.1002/ajim.4700190111
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:Silicosis is a progressive lung disease resulting from the inhalation of respirable crystalline silica. Lung transplantation is the only treatment for end-stage silicosis. The aim of this study was to analyze the survival experience following lung transplantation among patients with silicosis. METHODS:We re...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22687
更新日期：2017-03-01 00:00:00
abstract：:Attitudes of occupational health care professionals toward smoking and their activity to address smoking issues were investigated by a questionnaire survey. Data were also collected on employees' exposure to environmental tobacco smoke and on smoking policies that existed in workplaces. Questionnaires were mailed to a...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199807)34:1<73::aid-ajim10
更新日期：1998-07-01 00:00:00
abstract：AIMS:To examine the pattern of psychosocial risk exposures at work among wage-earners in Spain in 2005 and 2010, and to analyze changes in exposure inequalities by gender and job category. METHODS:Psychosocial exposures were compared using the COPSOQ-ISTAS21 method, based on two surveys representative of the Spanish w...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22334
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:The Fogarty International Center (FIC) of the United States National Institutes of Health includes the International Training and Research in Environmental and Occupational Health (ITREOH) Program. The "International Training Program in Environmental Toxicology and Public Health" Center, funded in 2002 is ba...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22044
更新日期：2013-01-01 00:00:00
abstract：:Methods to collect epidemiologic data include, among other means, self-administered questionnaires and personal and telephone interviews. In some studies, these data collection methods are used simultaneously. However, little is known about the comparability of the data obtained, thus, the validity of pooling data. A ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199705)31:5<653::aid-ajim2
更新日期：1997-05-01 00:00:00
abstract：BACKGROUND:Occupational health problems among home-helpers have been reported in a series of studies, and the need for intervention has been pointed out. To facilitate decisions regarding interventions and to establish baseline values for future evaluation of preventive efforts, the present study aimed to elucidate the...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.10028
更新日期：2002-01-01 00:00:00
abstract：:Nanoparticles are being used in ever increasing numbers in a range of industrial and medical products. Questions surrounding their potential to cause toxic effects in humans have been raised. Although animal experiments predict that nanoparticles are more toxic than their larger counterparts there are few descriptions...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20855
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:Engineering or administrative methods are often insufficient or impractical to control exposure to chemicals in anatomy laboratories. This study explored the feasibility of wearing one or a combination of respirators and goggles used as personal protective equipment (PPE) to control exposure in one such labo...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.10180
更新日期：2003-03-01 00:00:00
abstract：:Pressure from the vinyl chloride (VC) industry on researchers involved in industry-sponsored studies and on regulatory agencies has been documented since 1970s. This commentary describes the influence of a lawsuit pursued by workers of an Italian VC plant on the recent scientific debate on VC exposure and risk of hepa...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20941
更新日期：2011-06-01 00:00:00
abstract：:The oil and gas extraction industry is rapidly growing due to horizontal drilling and high volume hydraulic fracturing (HVHF). This growth has provided new jobs and economic stimulus. The industry occupational fatality rate is 2.5 times higher than the construction industry and 7 times higher than general industry; ho...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：10.1002/ajim.22316
更新日期：2014-07-01 00:00:00
abstract：:This commentary challenges a recently published perception that Dr. Le Roy Upson Gardner had not actually discovered in 1942 that inhaled chrysotile fibers could induce malignant neoplasia in mice. The handwritten laboratory notes and some of Dr. Gardner's slides have recently been found. They verify that the tumors h...
journal_title：American journal of industrial medicine
pub_type： 传,历史文章,杂志文章
doi：10.1002/ajim.4700270413
更新日期：1995-04-01 00:00:00
abstract：BACKGROUND:Per a Congressional directive and funding, this study describes worker and workplace characteristics of emergency department (ED) patients who reported their injury/illness to their employer. The study also responds to Congress's request to enumerate injured/ill self-employed workers and workers with chronic...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22607
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Hispanic immigrant workers dominate California's hired farm workforce. Little is known about their health status; even less is known about those lacking employment authorization. METHODS:The California Agricultural Workers Health Survey (CAWHS) was a statewide cross-sectional household survey conducted in 1...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20796
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Around the globe, work has a heavy impact on health. To better advise policy makers, we assessed the global burden of disease and injury due to selected occupational hazards. This article presents an overview, and describes the methodology employed in the companion studies. METHODS:Using the World Health Or...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20211
更新日期：2005-12-01 00:00:00
abstract：:The relationship between the time-weighted average intensity of exposure to toluene and o-cresol concentration in shift-end urine was investigated in nearly 500 factory workers of both sexes in China, together with a similar number of nonexposed control subjects. Toluene concentration (25 ppm as geometric mean and 550...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700250509
更新日期：1994-05-01 00:00:00
abstract：:We investigated an outbreak of irritative and neurotoxic symptoms associated with exposure to asphalt fumes in a commercial lighting factory; 27 symptomatic female workers were clinically assessed including hematologic testing. When compared with a laboratory reference group (n = 107), the workers' mean platelet volum...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700250214
更新日期：1994-02-01 00:00:00
abstract：:Pathologists eligible for inclusion in the study were identified from the membership lists of the Royal College of Pathologists from 1974 to 1987, establishing a population of 4,512 members. Overall mortality was lower among the study group compared with the general population of England and Wales, although there were...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700200108
更新日期：1991-01-01 00:00:00
abstract：:Very sensitive and precise analytical methods for measuring total porphyrin excretion and the relative amounts of different porphyrins in urine are required in order to monitor the biological effects of porphyrinogenic substances in workers and the general population. Many analytical steps of a HPLC method for measuri...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700040409
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND:A program of medical evaluation for former Savannah River Site (SRS) workers at health effects due to exposures to hazardous or radioactive agents was conducted. METHODS:This study includes data from 1,368 participants aged 45 years or older who were assessed regarding work-history and exposures to industri...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20224
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:Hotel room cleaners have physically demanding jobs that place them at high risk for shoulder pain. Psychosocial work factors may also play a role in shoulder pain, but their independent role has not been studied in this group. METHODS:Seventy-four percent (941 of 1,276) of hotel room cleaners from five Las ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20832
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:A 5-year longitudinal study examined nonmalignant respiratory effects of wood processing dust exposure. METHODS:Ten study plants, investigator selected from 447 candidate plants, included 1 sawmill-planing-plywood, 1 plywood, 1 milling, 3 cabinet and 4 furniture facilities. Personal dust samples (2363) were...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20594
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:The global burden of hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) infection due to percutaneous injuries among health care workers (HCWs) is estimated. METHODS:The incidence of infections attributable to percutaneous injuries in 14 geographical regions on the basis of the pro...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20230
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Hospital workers are a diverse population with high rates of musculoskeletal disorders (MSDs). The risk of MSD leading to workers' compensation (WC) claims is likely to show a gradient by socioeconomic status (SES) that may be partly explained by working conditions. METHODS:A single community hospital provi...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20702
更新日期：2009-07-01 00:00:00
abstract：INTRODUCTION:Live-in formal caregivers spend consecutive days in patients' homes, raising questions about their ability to secure adequate sleep while on duty. Few studies have examined sleeping conditions and outcomes for this growing workforce. METHODS:We collected weeklong sleep logs and interview data from 32 Fili...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22647
更新日期：2016-12-01 00:00:00
abstract：:We evaluated the cost and yield of a general health surveillance program emphasizing the identification of occupationally related diseases among workers in a high-risk trade. Of approximately 4,000 eligible members of two local plumbers and pipefitters unions, 639 were screened in this program. Screening tests indicat...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700130205
更新日期：1988-01-01 00:00:00
