Abstract:
BACKGROUND:The peripheral nerve conduction velocity (NCV), distribution of nerve conduction velocities (DCV), somatosensory, visual, and brainstem auditory evoked potentials (SEP, VEP, and BAEP, respectively), event-related potential (P300), computerized static posturography with spectral analysis (postural balance), and electrocardiographic R-R interval variability (CV(RR)) with spectral analysis appear to be promising techniques for assessing subclinical effects of lead on the peripheral, central and autonomic nervous systems. This article presents an overview of research addressing subclinical neurophysiological effects of lead in workers exposed to lead. METHODS:We reviewed 102 articles to examine the effects and dose-effects relationships of lead on peripheral, central, and autonomic nervous system function together with reversibility of the effects, interaction between lead and other metals, and relative sensitivity and specificity of each technique. Background and methodology were also reviewed. RESULTS AND CONCLUSION:Available data suggest that, on a group basis, the reduction in the NCV, together with the effects on the P300 latency, postural balance, and CV(RR), occurs at a mean blood lead concentration (BPb) as low as 30-40 microg/dL; the effects on the latencies of the short-latency SEP, VEP, and BAEP, as well as the DCV, start at a BPb as low as 40-50 microg/dL. Further cross-sectional and preferably prospective studies by using each of those methods are needed to establish more precise dose-effects (and response) relationships of lead.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Araki S,Sato H,Yokoyama K,Murata Kdoi
10.1002/(sici)1097-0274(200002)37:2<193::aid-ajim5subject
Has Abstractpub_date
2000-02-01 00:00:00pages
193-204issue
2eissn
0271-3586issn
1097-0274pii
10.1002/(SICI)1097-0274(200002)37:2<193::AID-AJIM5journal_volume
37pub_type
杂志文章,评审abstract::Blood histamine levels were measured by the bioassay of histamine (on an isolated strip of guinea pig ileum) in workers exposed to cotton dust in a textile mill in Ahmedabad. Byssinotic subjects showed very high levels of blood histamine as compared to nonbyssinotic and control subjects. The blood histamine levels wer...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120409
更新日期:1987-01-01 00:00:00
abstract::To determine the nature of respiratory functional impairment caused by asbestos-induced visceral pleural fibrosis (VPF) and to discover which pulmonary physiological variable best reveals it, we examined 59 asbestos-exposed construction workers having asbestos-related changes on chest radiographs. Computed tomography ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280306
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:The amount of information about hazardous agents in the workplace exceeds the capacity of human memory. There is a need to accurately represent or map this scientific knowledge for digital storage and retrieval. METHODS:A relational database of hazardous chemicals and occupational diseases was constructed b...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20578
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Neck pain is a prevalent musculoskeletal condition among workers in the United States. This study explores a set of workplace psychosocial and organization-related factors for neck pain. METHODS:Data used for this study come from the 2010 National Health Interview Survey which provides a representative samp...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22602
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Exposure to chemicals in polluted soil was studied during the remediation of four polluted sites. They are sawmill areas contaminated with chlorophenols and polychlorinated dibenzo-p-dioxins and furanes (PCDD/F), wood impregnating plants contaminated with polycyclic aromatic hydrocarbons (PAH) from creosote ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1031
更新日期:2001-04-01 00:00:00
abstract::Occupational health standards in the Scandinavian countries are of national concern and may thus vary from country to country. There is an internordic collaboration in the scientific criteria work, but there are also national formal procedures for standard setting. There is a greater tendency to accept eye, nose, or t...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700150602
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Autopsied lungs from 29 hard rock miners were investigated to determine the relationship of the dust content to pathology, radiology, and occupational exposure. METHODS:Each lung was divided horizontally into three sections. Pathological and radiological studies and chemical analyses were carried out on sam...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20589
更新日期:2008-07-01 00:00:00
abstract::We evaluated the cost and yield of a general health surveillance program emphasizing the identification of occupationally related diseases among workers in a high-risk trade. Of approximately 4,000 eligible members of two local plumbers and pipefitters unions, 639 were screened in this program. Screening tests indicat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700130205
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:As the sustainability of the agricultural workforce has been threatened by the high prevalence of back pain, developing effective interventions to reduce its burden within farming will contribute to the long-term health and productivity of workers. Passive back-support exoskeletons are being explored as an i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23180
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:In 2002, a voluntary registry of occupational respiratory diseases was initiated in the test phase in Asturias, Catalonia, and Navarre (Spain). Based on data from the fully implemented voluntary registry, we assessed the differences in the incidence and characteristics of the diseases reported in the three r...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20862
更新日期:2010-09-01 00:00:00
abstract::For various reasons, data on smoking are frequently missing, or only partially available, in retrospective epidemiologic studies of occupational risk factors. In such situations, indirect methods may be used to evaluate the magnitude and direction of the potentially confounding effects of smoking. Such an evaluation c...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700130107
更新日期:1988-01-01 00:00:00
abstract::There have long been case reports linking silica exposure to a variety of autoimmune diseases (systemic sclerosis, rheumatoid arthritis, lupus, chronic renal disease). Evidence of this association in larger epidemiologic studies has been increasing in the last decade. We summarize this evidence here, and present some ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700280505
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:The Mine Safety and Health Administration (MSHA) proposes to issue citations for non-compliance with the exposure limit for respirable coal mine dust when measured exposure exceeds the exposure limit with a "high degree of confidence." This criterion threshold value (CTV) is derived from the sampling and ana...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20318
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:After cryptosporidiosis was reported in three workers caring for preweaned calves at an academic research laboratory, we sought to identify cases, determine risk factors, and implement control measures. METHODS:A cryptosporidiosis case was defined as diarrhea duration ≥72 hr, abdominal cramps, or vomiting i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22630
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Exposure in the dental environment can increase the risk of respiratory disease in dental healthcare workers (HCWs). This study investigated the prevalence of asthma phenotypes in dental HCWs and associated risk factors. METHODS:A cross-sectional study of 454 dental HCWs in five dental institutions in South...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22041
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:Few Canadian data sources allow the examination of disparities by ethnicity, language, or immigrant status in occupational exposures or health outcomes. However, it is possible to document the mechanisms that can create disparities, such as the over-representation of population groups in high-risk jobs. We e...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20845
更新日期:2010-09-01 00:00:00
abstract::Animal studies show that antimony may cause lung cancer and heart and lung disease in rodents. In exposed humans, ECG abnormalities and heart and lung disease have been reported. This mortality study of 1,014 men employed between 1937 and 1971 in a Texas antimony smelter consisted primarily of workers of Spanish ances...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700270510
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:A 5-year longitudinal study examined nonmalignant respiratory effects of wood processing dust exposure. METHODS:Ten study plants, investigator selected from 447 candidate plants, included 1 sawmill-planing-plywood, 1 plywood, 1 milling, 3 cabinet and 4 furniture facilities. Personal dust samples (2363) were...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20594
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Mortality rates associated with total pneumoconiosis, including coal worker's pneumoconiosis (CWP), have remained elevated. METHODS:2003-2013 pneumoconiosis mortality data obtained from National Center for Health Statistics and 2011-2013 Kentucky death certificates were analyzed. RESULTS:Total pneumoconios...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22511
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Work-related asthma (WRA) is the most common work-associated respiratory disease in developed countries. METHOD:We report shark cartilage dust as a new potential cause of occupational asthma (OA) in the context of other fatal OA case reports. RESULTS:A 38-year-old white male worked for 8 years in a facilit...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.10088
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Respirable crystalline silica (RCS) can potentially cause silicosis, lung cancer, and renal failure. The current study estimates the percentages of workers potentially overexposed to concentrations of RCS dust and silicosis proportional mortality rates (PMRs) by industry. METHODS:Occupational Safety and Hea...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23109
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Workers in poultry processing and pork meatpacking have high rates of acute injuries and chronic disease among. The presence of zoonotic pathogens in these workplaces may interact with injury. METHODS:We investigated incidence of worker injuries, lacerations, and infections reported by 10 companies from 200...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22325
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Around the globe, work has a heavy impact on health. To better advise policy makers, we assessed the global burden of disease and injury due to selected occupational hazards. This article presents an overview, and describes the methodology employed in the companion studies. METHODS:Using the World Health Or...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20211
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Occupational eye injuries have been recognized as a serious health risk to workers and are in need of further investigation to develop effective interventions. METHODS:Rhode Island workers' compensation claims of ocular injury between 1998 through 2002 (n=8,877) were examined. The Current Population Survey ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20234
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The healthy survivor effect is a selection process whereby healthy workers are selectively retained in the work force while unhealthy workers are removed. Understanding this phenomenon is integral to the accurate assessment of exposure effects in occupational cohorts. To date, scarce information has been pub...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199904)35:4<343::aid-ajim4
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:Knowledge on intrapulmonary lymph nodes (IPLNs) is still limited. Progress in imaging techniques has enabled easier, more frequent visualization of IPLNs so that a more comprehensive understanding of these nodes is necessary. METHODS:Microscopic slides of lung tissue from 2,337 dust-exposed South African mi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20436
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Exposure to disinfectants among healthcare workers has been associated with respiratory health effects, in particular, asthma. However, most studies are cross-sectional and the role of disinfectant exposures in asthma development requires longitudinal studies. We investigated the association between occupati...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23067
更新日期:2020-01-01 00:00:00
abstract::Thirty-three U.S. Occupational Safety and Health Administration (OSHA) standards contain mandated medical service provisions. The German Berufsgenossenschaften Guidelines for Preventive Occupational Health Examinations currently comprise 38 guidelines, which contain mandated medical service provisions. Based on a prev...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199704)31:4<373::aid-ajim1
更新日期:1997-04-01 00:00:00
abstract::The evidence from animal studies indicates that organic extracts of diesel particulate are mutagenic and carcinogenic. Of four animal inhalation studies, two have been positive and two have been largely negative. The most recent data indicate that inhalation studies may be positive only with high doses of exhaust. Hum...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700100208
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:A study of occupational asthma among workers exposed to 4,4'-Diphenylmethane Diisocyanate (MDI). OBJECTIVE:To demonstrate if serum concentrations of MDI-specific IgG or IgE are sensitive biological markers of disease or of MDI exposure. METHODS:The study group consisted of nine MDI-exposed workers and nine...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199805)33:5<471::aid-ajim6
更新日期:1998-05-01 00:00:00