Abstract:
:Very sensitive and precise analytical methods for measuring total porphyrin excretion and the relative amounts of different porphyrins in urine are required in order to monitor the biological effects of porphyrinogenic substances in workers and the general population. Many analytical steps of a HPLC method for measuring porphyrins as methyl esters in urine have been perfected. Sensitivity is 0.1 microgram/1 for each type of porphyrin, and average recovery is 92% in the range of 50-450 micrograms/liter porphyrins. The coefficient of variation is 3.4% within a series and 12.5% between series. Chemical oxidation before analysis and appropriate storing of the samples are the key points in achieving high quality results. The urinary excretion of porphyrins in healthy male workers varies within the range 21 to 161 micrograms/liter (95% limits of a group of 78 subjects). Concomitant factors, like drug use or liver disorders, were found to alter urinary porphyrin excretion. The proposed method permits the detection of extremely small alterations in porphyrin excretion resulting from occupational exposure to industrial chemicals such as, for example, mild coproporphyrinuria or early stages of chemical porphyria induced by polyhalogenated arylhydrocarbons.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Colombi A,Maroni M,Ferioli A,Valla C,Coletti G,Foà Vdoi
10.1002/ajim.4700040409subject
Has Abstractpub_date
1983-01-01 00:00:00pages
551-64issue
4eissn
0271-3586issn
1097-0274journal_volume
4pub_type
杂志文章abstract:BACKGROUND:Many newly constructed green buildings (GB) are certified using the United States Green Building Council (USGBC) Leadership in Energy and Environmental Design (LEED) rating system for new construction and major renovation which focuses on architectural and mechanical design to conserve energy, reduce environ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22166
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Several case-control studies have found an association between chronic beryllium disease (CBD) and HLA-DPB1 gene variants. However, the relationship between HLA-DPB1 and beryllium sensitization, and whether the presence of one or two HLA-DPB1(Glu69) alleles is differentially associated with CBD and beryllium...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,多中心研究
doi:10.1002/ajim.20045
更新日期:2004-08-01 00:00:00
abstract::Cause-specific mortality was evaluated by period of hire for 37,682 male chemical workers in order to test the hypothesis that employees hired during World War II (1941-1945) were at increased risk for selected causes of death. One recent study of refinery workers reported that those hired during the war years had exp...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700150308
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Persistent and growing occupation-based disparities related to tobacco pose a serious public health challenge. Tobacco exacts a disproportionate toll on individuals employed in working class occupations, due to higher prevalence of smoking and exposure to secondhand smoke among these workers compared to othe...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20026
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Hexavalent chromium is widely recognized to be a lung carcinogen. However, the U.S. Occupational Safety and Health Administration (OSHA) has failed to reduce the permissible exposure limit (PEL), despite having acknowledged in 1994 that the current limit is too high. In 1993, Public Citizen and the Paper, Al...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10128
更新日期:2002-11-01 00:00:00
abstract::We conducted a comparative study of pulmonary dysfunction among workers who were exposed to silica, asbestos, or coalmine dust. The results showed that all three groups of dust-exposed workers, even those without radiographic signs of pneumoconiosis, had decreased spirometric parameters and diffusing capacity (DLco) i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199705)31:5<495::aid-ajim2
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:The community of Libby, Montana has recently been the focus of national attention secondary to widespread amphibole contamination associated with vermiculite mining and processing. METHODS:Patients who had occupational and non-occupational exposure to amphibole asbestos in Libby, Montana were evaluated for ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20053
更新日期:2004-09-01 00:00:00
abstract::Pathologists eligible for inclusion in the study were identified from the membership lists of the Royal College of Pathologists from 1974 to 1987, establishing a population of 4,512 members. Overall mortality was lower among the study group compared with the general population of England and Wales, although there were...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700200108
更新日期:1991-01-01 00:00:00
abstract::A retrospective exposure assessment study in the automotive parts industry conducted in conjunction with a cancer mortality and respiratory morbidity study [Kennedy et al. (1989): Am J Ind Med 15:627-641; Eisen et al. (1992): Am J Ind Med 22:809-824; Tolbert et al. (1992): Scand J Work Environ Health 18:351-360] descr...
journal_title:American journal of industrial medicine
pub_type: 历史文章,杂志文章
doi:10.1002/ajim.4700260505
更新日期:1994-11-01 00:00:00
abstract::Pesticides may be transformed by chemical and biological processes or transported from the site of application by several processes including runoff, movement through the soil to ground water, volatilization, transport on soil particles, and wind erosion. Contamination of water by pesticide residues is a matter of con...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700180418
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:The prerequisites necessary for attributing lung carcinoma to asbestos, represent a controversial issue. METHODS:Three parameters (occupational history, pleural plaques, and lung asbestos bodies) were investigated in 414 consecutive cases of lung carcinoma, examined at necropsy at the Hospital of Monfalcone...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199909)36:3<360::aid-ajim3
更新日期:1999-09-01 00:00:00
abstract::In a case-control study, 403 male patients with a diagnosis of "bladder tumor" and (as controls) 426 patients suffering from prostate disease were investigated. The results of this study indicate that past employment as a painter was associated with an excess risk of bladder tumor. The relative risk of bladder tumor e...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700190604
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to examine the association between Dupuytren's contracture (DC), repetitive handwork (RHW), heavy handwork (HHW), and/or vibration exposure. METHODS:Frequency and intensity of the three types of handwork were collected and compared between DC patients and controls. Hours of wo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22736
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The aims of this study were to compare job demand-control (JDC) and effort-reward imbalance (ERI) models in examining the association of job stress with work-related musculoskeletal symptoms and to evaluate the utility of a combined model. METHODS:This study analyzed cross-sectional survey data obtained fro...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22274
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:There are relatively few studies of large national databases that contain information on working hours and health. The current study involved an analysis of data from a quality of work life (QWL) module developed for the 2002 General Social Survey. This module collected work and health data from a representa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20388
更新日期:2006-11-01 00:00:00
abstract:Background:Little research has addressed the safety environment of child farmworkers. This analysis examines the work safety culture experienced by Latinx child farmworkers in North Carolina. Methods:Survey interviews were conducted in 2017 with 202 Latinx children aged 10 to 17 years employed on North Carolina farms....
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23161
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Pulmonary tuberculosis and HIV incidence, mortality, and the progression of silicosis and lung function impairment are described over a 1-year period in migrant ex-gold miners from Lesotho. METHODS:Seven hundred seventy-nine Basotho miners were followed for 1 year starting 18 months after lay-off from a Sou...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20767
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Hotel room cleaners have physically demanding jobs that place them at high risk for shoulder pain. Psychosocial work factors may also play a role in shoulder pain, but their independent role has not been studied in this group. METHODS:Seventy-four percent (941 of 1,276) of hotel room cleaners from five Las ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20832
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:In the city of Petrópolis, Brazil, artisans carve souvenirs from a variety of silica-containing minerals. The finding of pulmonary massive fibrosis in one of the workers motivated an investigation of the prevalence of silicosis in this group. METHODS:Between January 2000 and June 2002, a cross-sectional stu...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10331
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Work-related mortality is a relatively new concept which aims to widen occupational health and safety; to take into account not only recognized fatal occupational accidents and diseases but also other work-related deaths. Few countries in the world have a register for work-related diseases. METHODS:Estimate...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20411
更新日期:2007-01-01 00:00:00
abstract::Formaldehyde is commonly accepted to be an allergen and irritant. However, specifically diagnosed occupational respiratory diseases caused by formaldehyde are relatively rare. Occupational laryngitis was diagnosed in a 47-year-old dairy foreman. He had been exposed for 9 years to formaldehyde emitted from a milk-packi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0274(199603)29:3<275::AID-AJIM7
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Rates of musculoskeletal disorders in construction remain high. Few studies have described barriers and facilitators to the use of available ergonomic solutions. This paper describes these barriers and facilitators and their relationship to the level of adoption. METHODS:Three analysts rated 16 proposed erg...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22693
更新日期:2017-03-01 00:00:00
abstract::In view of the increasing incidence of diseases such as gastritis and ulcers in workers exposed to noise, we assessed whether noise does in fact affect gastric secretion. Then, considering the conflicting findings published on the effects of noise on gastric secretion, we also investigated whether the response was rel...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700260310
更新日期:1994-09-01 00:00:00
abstract::Assessing the health risks of complex mixtures of polynuclear aromatic hydrocarbons such as diesel fumes and asphalt or bitumen continues to be a major challenge for occupational and environmental health scientists. The special Asphalt issue of the American Journal of Industrial Medicine (Cancer Mortality Among Europe...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10215
更新日期:2003-03-01 00:00:00
abstract::This retrospective analysis reviews the clinical experience of a major urban referral hospital with diffuse malignant pleural mesothelioma during the 14-year period from 1973 through 1986. Seventy-five cases of definite or equivocal mesothelioma were identified. There were four cases of primary malignant peritoneal me...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700160405
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:A number of employees at an aircraft factory were accidentally exposed to hydrogen sulfide. Because of concern that this may have resulted in lung injury, forty-seven workers were referred for clinical and physiological evaluation. METHODS:Comprehensive pulmonary function tests were performed including spir...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0274(200003)37:3<296::aid-ajim8
更新日期:2000-03-01 00:00:00
abstract::In 1979, a pilot survey defined respiratory status and unmet health care needs of retired and former male asbestos workers in Hawaii. Of 1,401 identified subjects, 741 were contacted and 411 were interviewed. Forty-five subjects were between 39 and 54 years of age; 208, between 55 and 64; and 158, age 65 or more. They...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700060208
更新日期:1984-01-01 00:00:00
abstract::Artificial intelligence (AI) is a broad transdisciplinary field with roots in logic, statistics, cognitive psychology, decision theory, neuroscience, linguistics, cybernetics, and computer engineering. The modern field of AI began at a small summer workshop at Dartmouth College in 1956. Since then, AI applications mad...
journal_title:American journal of industrial medicine
pub_type: 历史文章,杂志文章,评审
doi:10.1002/ajim.23037
更新日期:2019-11-01 00:00:00
abstract::The objectives of this study were 1) to summarize in a clinically meaningful way information on occupational risk factors for carpal tunnel syndrome (CTS), and 2) to test a questionnaire on risk factors that could be used by physicians with their patients. For the two objectives, a systematic literature review was per...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0274(199803)33:3<224::aid-ajim3
更新日期:1998-03-01 00:00:00
abstract::Seven cases of fiberglass dermatitis among production operators in the electronics industry are reported. This was due to the repeated daily handling of printed circuit boards (PRCBs). The predominant complaint of the workers was itch of the lateral aspects of the fingers and finger webs. In six workers, unroofed vesi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700210208
更新日期:1992-01-01 00:00:00